DE60018744D1 - Komplex von Eletriptan und Sulfobutylether-cyclodextrin und dessen Verwendung zur Behandlung von Migräne - Google Patents

Komplex von Eletriptan und Sulfobutylether-cyclodextrin und dessen Verwendung zur Behandlung von Migräne

Info

Publication number
DE60018744D1
DE60018744D1 DE60018744T DE60018744T DE60018744D1 DE 60018744 D1 DE60018744 D1 DE 60018744D1 DE 60018744 T DE60018744 T DE 60018744T DE 60018744 T DE60018744 T DE 60018744T DE 60018744 D1 DE60018744 D1 DE 60018744D1
Authority
DE
Germany
Prior art keywords
eletriptan
migraine
complex
treatment
sulfobutyl ether
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60018744T
Other languages
English (en)
Other versions
DE60018744T2 (de
Inventor
Anne Billotte
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of DE60018744D1 publication Critical patent/DE60018744D1/de
Application granted granted Critical
Publication of DE60018744T2 publication Critical patent/DE60018744T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Nanotechnology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Addiction (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60018744T 1999-06-29 2000-06-02 Komplex von Eletriptan und Sulfobutylether-cyclodextrin und dessen Verwendung zur Behandlung von Migräne Expired - Lifetime DE60018744T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9915231 1999-06-29
GBGB9915231.6A GB9915231D0 (en) 1999-06-29 1999-06-29 Pharmaceutical complex
PCT/IB2000/000746 WO2001000243A1 (en) 1999-06-29 2000-06-02 Pharmaceutical complex

Publications (2)

Publication Number Publication Date
DE60018744D1 true DE60018744D1 (de) 2005-04-21
DE60018744T2 DE60018744T2 (de) 2006-05-18

Family

ID=10856302

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60018744T Expired - Lifetime DE60018744T2 (de) 1999-06-29 2000-06-02 Komplex von Eletriptan und Sulfobutylether-cyclodextrin und dessen Verwendung zur Behandlung von Migräne

Country Status (44)

Country Link
US (2) US6713461B1 (de)
EP (1) EP1189640B1 (de)
JP (2) JP4454900B2 (de)
KR (1) KR20020015067A (de)
CN (1) CN1198654C (de)
AP (1) AP2001002369A0 (de)
AR (1) AR033337A1 (de)
AT (1) ATE290884T1 (de)
AU (1) AU770169B2 (de)
BG (1) BG106151A (de)
BR (1) BR0011845A (de)
CA (1) CA2376847C (de)
CO (1) CO5170494A1 (de)
CZ (1) CZ20014572A3 (de)
DE (1) DE60018744T2 (de)
DZ (1) DZ3320A1 (de)
EA (1) EA003908B1 (de)
EC (1) ECSP003551A (de)
EE (1) EE200100697A (de)
ES (1) ES2235879T3 (de)
GB (1) GB9915231D0 (de)
GE (1) GEP20043377B (de)
GT (1) GT200000102A (de)
HR (1) HRP20010951A2 (de)
HU (1) HUP0201629A3 (de)
IL (1) IL146341A0 (de)
IS (1) IS6163A (de)
MA (1) MA26801A1 (de)
MX (1) MXPA01013274A (de)
NO (1) NO20016430L (de)
NZ (1) NZ515235A (de)
OA (1) OA11964A (de)
PA (1) PA8496801A1 (de)
PE (1) PE20010346A1 (de)
PL (1) PL352902A1 (de)
SK (1) SK18932001A3 (de)
SV (1) SV2002000112A (de)
TN (1) TNSN00142A1 (de)
TR (1) TR200103827T2 (de)
UA (1) UA66932C2 (de)
UY (1) UY26224A1 (de)
WO (1) WO2001000243A1 (de)
YU (1) YU87501A (de)
ZA (1) ZA200110454B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9915231D0 (en) * 1999-06-29 1999-09-01 Pfizer Ltd Pharmaceutical complex
RU2342931C2 (ru) * 2002-08-20 2009-01-10 Бристол-Маерс Сквибб Компани Состав на основе комплекса арипипразола
GB0329918D0 (en) * 2003-12-24 2004-01-28 West Pharm Serv Drug Res Ltd Intranasal compositions
CN1296391C (zh) * 2004-03-04 2007-01-24 中国人民解放军第二军医大学 氟代羧烷基环糊精醚类化合物及其制备方法和应用
GB0613925D0 (en) 2006-07-13 2006-08-23 Unilever Plc Improvements relating to nanodispersions
CN101957330B (zh) * 2010-06-12 2013-10-09 南京巨环医药科技开发有限公司 磺丁基倍他环糊精含量的测定方法
WO2017122161A1 (en) * 2016-01-15 2017-07-20 Cadila Healthcare Limited An intranasal composition comprising 5ht1b/1d receptor agonists
WO2019143925A1 (en) * 2018-01-22 2019-07-25 Insys Development Company, Inc. Liquid rizatriptan compositions

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995024221A1 (en) 1986-08-18 1995-09-14 The Dow Chemical Company Bioactive and/or targeted dendrimer conjugates
KR0166088B1 (ko) * 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5376645A (en) * 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
HU210921B (en) 1990-03-28 1995-09-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing inclusion complexes of n-ethoxycarbonyl-3-morpholino-sydnonimine formed with cyclodextrines and pharmaceutical compositions containing them
HU212730B (en) 1990-03-28 1996-10-28 Chinoin Gyogyszer Es Vegyeszet Process for producing inclusion complexes of cyclodextrine or its derivative and 3-morpholino-sydnonimine or its salt or its tautomer and pharmaceutical compositions containing them
AU651637B2 (en) 1990-10-15 1994-07-28 Pfizer Inc. Indole derivatives
US5665767A (en) 1993-03-05 1997-09-09 Hexal Pharma Gmbh Crystalline cyclodextrin complexes of ranitidine hydrochloride, process for their preparation and pharmaceutical compositions containing the same
GB9417310D0 (en) 1994-08-27 1994-10-19 Pfizer Ltd Therapeutic agents
EP1024833A1 (de) 1996-07-11 2000-08-09 Farmarc Nederland B.V. Pharmazeutische zusammensetzung mit saurem zusatzsalz der basischen droge
US5998462A (en) 1996-12-16 1999-12-07 Allelix Biopharmaceuticals Inc. 5-alkyl indole compounds
GB9704498D0 (en) 1997-03-05 1997-04-23 Glaxo Wellcome Spa Chemical compound
WO1999001135A1 (en) 1997-07-03 1999-01-14 Pfizer Limited Pharmaceutical compositions containing eletriptan hemisulphate and caffeine
GB9816556D0 (en) * 1998-07-30 1998-09-30 Pfizer Ltd Therapy
GB9915231D0 (en) * 1999-06-29 1999-09-01 Pfizer Ltd Pharmaceutical complex

Also Published As

Publication number Publication date
AU770169B2 (en) 2004-02-12
AP2001002369A0 (en) 2001-12-31
SV2002000112A (es) 2002-02-05
IS6163A (is) 2001-11-16
NO20016430L (no) 2002-02-26
CZ20014572A3 (cs) 2002-08-14
BG106151A (en) 2002-05-31
AR033337A1 (es) 2003-12-17
EA200101106A1 (ru) 2002-06-27
DZ3320A1 (fr) 2001-01-04
JP2003503364A (ja) 2003-01-28
PL352902A1 (en) 2003-09-22
US20040186076A1 (en) 2004-09-23
JP2006257091A (ja) 2006-09-28
NZ515235A (en) 2003-08-29
PE20010346A1 (es) 2001-03-26
IL146341A0 (en) 2002-07-25
EA003908B1 (ru) 2003-10-30
EP1189640B1 (de) 2005-03-16
ATE290884T1 (de) 2005-04-15
PA8496801A1 (es) 2002-02-21
KR20020015067A (ko) 2002-02-27
OA11964A (en) 2006-04-17
HRP20010951A2 (en) 2005-04-30
CA2376847A1 (en) 2001-01-04
MXPA01013274A (es) 2002-06-04
DE60018744T2 (de) 2006-05-18
EP1189640A1 (de) 2002-03-27
CN1359303A (zh) 2002-07-17
UY26224A1 (es) 2001-01-31
AU4774100A (en) 2001-01-31
UA66932C2 (en) 2004-06-15
GB9915231D0 (en) 1999-09-01
YU87501A (sh) 2004-05-12
HUP0201629A3 (en) 2003-11-28
ECSP003551A (es) 2002-01-25
TNSN00142A1 (fr) 2005-11-10
SK18932001A3 (sk) 2002-09-10
WO2001000243A1 (en) 2001-01-04
TR200103827T2 (tr) 2002-05-21
NO20016430D0 (no) 2001-12-28
CN1198654C (zh) 2005-04-27
ES2235879T3 (es) 2005-07-16
US6713461B1 (en) 2004-03-30
BR0011845A (pt) 2002-03-05
JP4454900B2 (ja) 2010-04-21
EE200100697A (et) 2003-02-17
MA26801A1 (fr) 2004-12-20
CA2376847C (en) 2007-09-25
ZA200110454B (en) 2002-12-20
CO5170494A1 (es) 2002-06-27
GT200000102A (es) 2001-12-14
GEP20043377B (en) 2004-04-13
HUP0201629A2 (hu) 2003-03-28

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