DE60017133D1 - Naphthoquinone derivatives and their use in the treatment and control of tuberculosis - Google Patents

Naphthoquinone derivatives and their use in the treatment and control of tuberculosis

Info

Publication number
DE60017133D1
DE60017133D1 DE60017133T DE60017133T DE60017133D1 DE 60017133 D1 DE60017133 D1 DE 60017133D1 DE 60017133 T DE60017133 T DE 60017133T DE 60017133 T DE60017133 T DE 60017133T DE 60017133 D1 DE60017133 D1 DE 60017133D1
Authority
DE
Germany
Prior art keywords
tuberculosis
treatment
control
naphthoquinone derivatives
naphthoquinone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60017133T
Other languages
German (de)
Other versions
DE60017133T2 (en
Inventor
Jacobus Johannes Marion Meyer
Namrita Lall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
South African Medical Research Council
University of Pretoria
Medical Research Council of South Africa
Original Assignee
South African Medical Research Council
University of Pretoria
Medical Research Council of South Africa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by South African Medical Research Council, University of Pretoria, Medical Research Council of South Africa filed Critical South African Medical Research Council
Application granted granted Critical
Publication of DE60017133D1 publication Critical patent/DE60017133D1/en
Publication of DE60017133T2 publication Critical patent/DE60017133T2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60017133T 1999-06-24 2000-06-22 Naphthoquinone derivatives and their use in the treatment and control of tuberculosis Expired - Fee Related DE60017133T2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ZA994176 1999-06-24
ZA9904176 1999-06-24
PCT/IB2000/000837 WO2001000554A2 (en) 1999-06-24 2000-06-22 Naphthoquinone derivatives and their use in the treatment and control of tuberculosis

Publications (2)

Publication Number Publication Date
DE60017133D1 true DE60017133D1 (en) 2005-02-03
DE60017133T2 DE60017133T2 (en) 2005-06-16

Family

ID=25587788

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60017133T Expired - Fee Related DE60017133T2 (en) 1999-06-24 2000-06-22 Naphthoquinone derivatives and their use in the treatment and control of tuberculosis

Country Status (9)

Country Link
US (1) US6835755B1 (en)
EP (1) EP1194137B1 (en)
JP (1) JP2003531813A (en)
CN (1) CN1192768C (en)
AP (1) AP1377A (en)
AU (1) AU5240700A (en)
DE (1) DE60017133T2 (en)
RU (1) RU2246299C2 (en)
WO (1) WO2001000554A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2864955B1 (en) * 2004-01-08 2006-03-10 Centre Nat Rech Scient GOSSYPOL DERIVATIVES, METHOD FOR OBTAINING THEM AND USES THEREOF
US8410109B2 (en) * 2005-07-29 2013-04-02 Resverlogix Corp. Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
WO2008092231A1 (en) 2007-02-01 2008-08-07 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular diseases
AU2009262252B2 (en) 2008-06-26 2013-05-02 Resverlogix Corp. Methods of preparing quinazolinone derivatives
ES2463097T3 (en) 2009-01-08 2014-05-27 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular diseases
JP5795304B2 (en) 2009-03-18 2015-10-14 レスバーロジックス コーポレイション New anti-inflammatory agent
KR102215167B1 (en) 2009-04-22 2021-02-16 리스버로직스 코퍼레이션 Novel anti-inflammatory agents
CN101669927B (en) * 2009-09-22 2012-02-29 中山大学 Application of anthraquinone ZSU-H85 for preparing mycobacterium smegmatis resistant drugs
PT2773354T (en) 2011-11-01 2019-07-17 Resverlogix Corp Oral immediate release formulations for substituted quinazolinones
WO2014080290A2 (en) 2012-11-21 2014-05-30 Rvx Therapeutics Inc. Cyclic amines as bromodomain inhibitors
US9765039B2 (en) 2012-11-21 2017-09-19 Zenith Epigenetics Ltd. Biaryl derivatives as bromodomain inhibitors
WO2014096965A2 (en) 2012-12-21 2014-06-26 Rvx Therapeutics Inc. Novel heterocyclic compounds as bromodomain inhibitors
EP3268007B1 (en) 2015-03-13 2022-11-09 Resverlogix Corp. Compositions and therapeutic methods for the treatment of complement-associated diseases
CN106176709B (en) * 2015-05-26 2020-02-07 顺天乡大学校产学协力团 Pharmaceutical composition for treating tuberculosis and preparation method thereof
KR101851377B1 (en) * 2015-05-26 2018-06-05 순천향대학교 산학협력단 Composition containing compound for tuberculosis therapeutics and preparation method for the same
CN109730984A (en) * 2019-01-18 2019-05-10 天津国际生物医药联合研究院 Application of the 1,4- naphthoquinones in Killing Mycobacterium Tuberculosis infection
CN110075095A (en) * 2019-04-15 2019-08-02 天津国际生物医药联合研究院 Application of the 1,4- naphthoquinones in Killing Mycobacterium Tuberculosis infection

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4837399A (en) * 1988-05-10 1989-06-06 The United States Of America As Represented By The Secretary Of Agriculture Napthoquinone antibiotics from fuserium solani

Also Published As

Publication number Publication date
EP1194137A2 (en) 2002-04-10
AP1377A (en) 2005-03-18
CN1372464A (en) 2002-10-02
JP2003531813A (en) 2003-10-28
AP2002002393A0 (en) 2002-03-31
US6835755B1 (en) 2004-12-28
EP1194137B1 (en) 2004-12-29
DE60017133T2 (en) 2005-06-16
AU5240700A (en) 2001-01-31
RU2246299C2 (en) 2005-02-20
WO2001000554A3 (en) 2001-07-05
CN1192768C (en) 2005-03-16
WO2001000554A2 (en) 2001-01-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee