DE60010921D1 - Künstliche chromosomen, die die genetische information für die bildung von rekombinantem rna-virus enthalten - Google Patents

Künstliche chromosomen, die die genetische information für die bildung von rekombinantem rna-virus enthalten

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Publication number
DE60010921D1
DE60010921D1 DE60010921T DE60010921T DE60010921D1 DE 60010921 D1 DE60010921 D1 DE 60010921D1 DE 60010921 T DE60010921 T DE 60010921T DE 60010921 T DE60010921 T DE 60010921T DE 60010921 D1 DE60010921 D1 DE 60010921D1
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DE
Germany
Prior art keywords
formation
genetic information
rna virus
artificial chromosomes
recombinant rna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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DE60010921T
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English (en)
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DE60010921T2 (de
DE60010921T3 (de
Inventor
Sanchez Luis Enjuanes
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Consejo Superior de Investigaciones Cientificas CSIC
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Consejo Superior de Investigaciones Cientificas CSIC
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Publication of DE60010921D1 publication Critical patent/DE60010921D1/de
Publication of DE60010921T2 publication Critical patent/DE60010921T2/de
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Publication of DE60010921T3 publication Critical patent/DE60010921T3/de
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/215—Coronaviridae, e.g. avian infectious bronchitis virus
    • A61K39/225—Porcine transmissible gastroenteritis virus
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P11/00—Drugs for disorders of the respiratory system
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20041—Use of virus, viral particle or viral elements as a vector
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    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
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    • C12N2800/00—Nucleic acids vectors
    • C12N2800/20—Pseudochromosomes, minichrosomosomes
    • C12N2800/204—Pseudochromosomes, minichrosomosomes of bacterial origin, e.g. BAC
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    • C12N2800/00—Nucleic acids vectors
    • C12N2800/80—Vectors containing sites for inducing double-stranded breaks, e.g. meganuclease restriction sites

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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE60010921T 1999-12-03 2000-11-30 Künstliche chromosomen, die die genetische information für die bildung von rekombinantem rna-virus enthalten Expired - Lifetime DE60010921T3 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES009902673A ES2170622B1 (es) 1999-12-03 1999-12-03 Clones y vectores infectivos derivados de coronavirus y sus aplicaciones.
ES9902673 1999-12-03
PCT/EP2000/012063 WO2001039797A2 (en) 1999-12-03 2000-11-30 Artificial chromosome constructs containing nucleic acid sequences capable of directing the formation of a recombinant rna-virus

Publications (3)

Publication Number Publication Date
DE60010921D1 true DE60010921D1 (de) 2004-06-24
DE60010921T2 DE60010921T2 (de) 2006-05-11
DE60010921T3 DE60010921T3 (de) 2011-01-05

Family

ID=8310818

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Application Number Title Priority Date Filing Date
DE60010921T Expired - Lifetime DE60010921T3 (de) 1999-12-03 2000-11-30 Künstliche chromosomen, die die genetische information für die bildung von rekombinantem rna-virus enthalten

Country Status (27)

Country Link
US (4) US7445928B2 (de)
EP (2) EP1234024B2 (de)
JP (1) JP4637432B2 (de)
KR (1) KR100755814B1 (de)
CN (3) CN1616670A (de)
AR (1) AR027893A1 (de)
AT (1) ATE267246T1 (de)
AU (2) AU785081B2 (de)
BR (1) BR0016145A (de)
CA (1) CA2393325A1 (de)
CZ (1) CZ302785B6 (de)
DE (1) DE60010921T3 (de)
DK (1) DK1234024T4 (de)
ES (2) ES2170622B1 (de)
HU (1) HU228205B1 (de)
IL (2) IL149859A0 (de)
MX (1) MXPA02005525A (de)
NO (1) NO331812B1 (de)
NZ (1) NZ518990A (de)
PL (1) PL206816B1 (de)
PT (1) PT1234024E (de)
RS (1) RS50372B (de)
SI (1) SI1234024T2 (de)
SK (1) SK7612002A3 (de)
TR (1) TR200401186T4 (de)
WO (1) WO2001039797A2 (de)
ZA (1) ZA200203560B (de)

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AU2015259470A1 (en) * 2014-05-16 2016-11-10 Yale University Virus like vesicles (VLVs) based vaccines to prevent or treat chronic hepatitis B virus (HBV) infection
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CN107190022B (zh) * 2017-06-28 2020-10-30 浙江大学 一种快速构建禽传染性支气管炎病毒反向遗传株的方法
US11254953B2 (en) * 2018-04-18 2022-02-22 Utah State University Compositions and methods for zika virus characterization and vaccine development
KR102119875B1 (ko) * 2019-03-19 2020-06-05 한국화학연구원 한국형 중동호흡기증후군 코로나바이러스 감염성 변이 유전자 및 이의 용도
CN110468113A (zh) * 2019-08-07 2019-11-19 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） 重组修饰的猪传染性胃肠炎病毒强毒株及其应用
CN110656120A (zh) * 2019-10-16 2020-01-07 中国医学科学院医学生物学研究所 一种乙脑病毒sa14-14-2的克隆方法及应用
CN111662885A (zh) * 2020-06-22 2020-09-15 扬州大学 两株基因组高度同源猪繁殖与呼吸综合征病毒强弱毒株感染性克隆构建、拯救与应用
CN112852873B (zh) * 2021-02-04 2023-03-24 华中农业大学 一种猪δ冠状病毒感染性克隆质粒的构建方法
CN115094142B (zh) * 2022-07-19 2024-05-28 中国医学科学院肿瘤医院 用于诊断肺肠型腺癌的甲基化标志物

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US20040086846A1 (en) 2004-05-06
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