DE59104870D1 - Orale Arzneiform und Überzugsmittel, enthaltend ein im Colon abbaubares Polysaccharid. - Google Patents

Orale Arzneiform und Überzugsmittel, enthaltend ein im Colon abbaubares Polysaccharid.

Info

Publication number
DE59104870D1
DE59104870D1 DE59104870T DE59104870T DE59104870D1 DE 59104870 D1 DE59104870 D1 DE 59104870D1 DE 59104870 T DE59104870 T DE 59104870T DE 59104870 T DE59104870 T DE 59104870T DE 59104870 D1 DE59104870 D1 DE 59104870D1
Authority
DE
Germany
Prior art keywords
colon
degradable
polysaccharide
dosage form
coating agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE59104870T
Other languages
English (en)
Inventor
Klaus Dr Lehmann
Dieter Dreher
Pascali Giuseppe De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roehm GmbH Darmstadt
Original Assignee
Roehm GmbH Darmstadt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6859318&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE59104870(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Roehm GmbH Darmstadt filed Critical Roehm GmbH Darmstadt
Priority to DE59104870T priority Critical patent/DE59104870D1/de
Application granted granted Critical
Publication of DE59104870D1 publication Critical patent/DE59104870D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE59104870T 1990-11-14 1991-11-04 Orale Arzneiform und Überzugsmittel, enthaltend ein im Colon abbaubares Polysaccharid. Expired - Fee Related DE59104870D1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE59104870T DE59104870D1 (de) 1990-11-14 1991-11-04 Orale Arzneiform und Überzugsmittel, enthaltend ein im Colon abbaubares Polysaccharid.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE9015551U DE9015551U1 (de) 1990-11-14 1990-11-14
DE59104870T DE59104870D1 (de) 1990-11-14 1991-11-04 Orale Arzneiform und Überzugsmittel, enthaltend ein im Colon abbaubares Polysaccharid.

Publications (1)

Publication Number Publication Date
DE59104870D1 true DE59104870D1 (de) 1995-04-13

Family

ID=6859318

Family Applications (2)

Application Number Title Priority Date Filing Date
DE9015551U Expired - Lifetime DE9015551U1 (de) 1990-11-14 1990-11-14
DE59104870T Expired - Fee Related DE59104870D1 (de) 1990-11-14 1991-11-04 Orale Arzneiform und Überzugsmittel, enthaltend ein im Colon abbaubares Polysaccharid.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE9015551U Expired - Lifetime DE9015551U1 (de) 1990-11-14 1990-11-14

Country Status (5)

Country Link
EP (1) EP0485840B2 (de)
AT (1) ATE119389T1 (de)
DE (2) DE9015551U1 (de)
DK (1) DK0485840T4 (de)
ES (1) ES2071889T5 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4236025A1 (de) * 1992-10-24 1994-04-28 Merck Patent Gmbh Orale Arzneiformen
EP0670717B1 (de) * 1992-11-30 1998-11-25 Pfizer Inc. Verabreichungsvorrichtungen mit gestützten flüssigen membranen
US5656290A (en) * 1993-02-26 1997-08-12 The Procter & Gamble Company Bisacodyl dosage form with multiple enteric polymer coatings for colonic delivery
US5843479A (en) * 1993-02-26 1998-12-01 The Procter & Gamble Company Bisacodyl dosage form with multiple enteric polymer coatings for colonic delivery
DE4332394A1 (de) * 1993-09-23 1995-03-30 Falk Pharma Gmbh Budesonid-Pellets mit kontrolliertem Freigabeprofil und Verfahren zu ihrer Herstellung
US5849327A (en) * 1994-07-29 1998-12-15 Advanced Polymer Systems, Inc. Delivery of drugs to the lower gastrointestinal tract
US5811388A (en) * 1995-06-07 1998-09-22 Cibus Pharmaceutical, Inc. Delivery of drugs to the lower GI tract
US5656294A (en) * 1995-06-07 1997-08-12 Cibus Pharmaceutical, Inc. Colonic delivery of drugs
US5840332A (en) * 1996-01-18 1998-11-24 Perio Products Ltd. Gastrointestinal drug delivery system
AU1751997A (en) * 1996-01-30 1997-08-22 Advanced Polymer Systems Inc. Targeted delivery of drugs to the lower gastrointestinal tract
KR100219918B1 (ko) * 1997-07-03 1999-09-01 김윤 대장선택적 약물전달용 조성물
DE19732903A1 (de) 1997-07-30 1999-02-04 Falk Pharma Gmbh Pellet-Formulierung zur Behandlung des Intestinaltraktes
KR20000011247A (ko) * 1998-07-23 2000-02-25 김윤 다당류를이용한대장선택성약물전달조성물및약학제제
US6531152B1 (en) 1998-09-30 2003-03-11 Dexcel Pharma Technologies Ltd. Immediate release gastrointestinal drug delivery system
US6632451B2 (en) 1999-06-04 2003-10-14 Dexcel Pharma Technologies Ltd. Delayed total release two pulse gastrointestinal drug delivery system
GB2367002A (en) * 2000-09-25 2002-03-27 British Sugar Plc Coating composition
US6590059B2 (en) 2001-05-11 2003-07-08 Ap Pharma, Inc. Bioerodible polyorthoesters from dioxolane-based diketene acetals
DE10209979A1 (de) * 2002-03-07 2003-09-25 Ratiopharm Gmbh Arzneimittel mit Cholesterolspiegel-senkenden Wirkstoffen mit zeitverzögerter Wirkstofffreisetzung
MX2011003595A (es) 2008-10-03 2011-07-28 Falk Pharma Gmbh Composiciones y metodos para el tratamiento de enfermedades intestinales con mesalamina granulada.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3405378A1 (de) * 1984-02-15 1985-08-22 Röhm GmbH, 6100 Darmstadt Arzneimittelueberzug
DE3827561C1 (de) * 1988-08-13 1989-12-28 Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De
FR2663222A1 (fr) * 1990-06-13 1991-12-20 Medgenix Group Sa Microcapsule de liquide huileux.

Also Published As

Publication number Publication date
ES2071889T3 (es) 1995-07-01
ATE119389T1 (de) 1995-03-15
EP0485840B1 (de) 1995-03-08
ES2071889T5 (es) 1999-07-01
DE9015551U1 (de) 1992-03-12
DK0485840T3 (da) 1995-06-06
EP0485840B2 (de) 1999-03-03
EP0485840A3 (en) 1992-11-25
DK0485840T4 (da) 1999-10-04
EP0485840A2 (de) 1992-05-20

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings
8327 Change in the person/name/address of the patent owner

Owner name: ROEHM GMBH & CO. KG, 64293 DARMSTADT, DE

8327 Change in the person/name/address of the patent owner

Owner name: ROEHM GMBH, 64293 DARMSTADT, DE

8327 Change in the person/name/address of the patent owner

Owner name: EVONIK ROEHM GMBH, 64293 DARMSTADT, DE

8339 Ceased/non-payment of the annual fee