DE3882739D1 - Matrix-zubereitungen mit verzoegerter freisetzung. - Google Patents

Matrix-zubereitungen mit verzoegerter freisetzung.

Info

Publication number
DE3882739D1
DE3882739D1 DE8888301684T DE3882739T DE3882739D1 DE 3882739 D1 DE3882739 D1 DE 3882739D1 DE 8888301684 T DE8888301684 T DE 8888301684T DE 3882739 T DE3882739 T DE 3882739T DE 3882739 D1 DE3882739 D1 DE 3882739D1
Authority
DE
Germany
Prior art keywords
delayed release
matrix preparations
preparations
matrix
delayed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8888301684T
Other languages
English (en)
Other versions
DE3882739T2 (de
Inventor
Peter Lloyd Oren
Werner Max Karl Seidler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of DE3882739D1 publication Critical patent/DE3882739D1/de
Application granted granted Critical
Publication of DE3882739T2 publication Critical patent/DE3882739T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
DE88301684T 1987-02-27 1988-02-26 Matrix-Zubereitungen mit verzögerter Freisetzung. Expired - Lifetime DE3882739T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1991587A 1987-02-27 1987-02-27

Publications (2)

Publication Number Publication Date
DE3882739D1 true DE3882739D1 (de) 1993-09-16
DE3882739T2 DE3882739T2 (de) 1994-02-17

Family

ID=21795732

Family Applications (2)

Application Number Title Priority Date Filing Date
DE198888301684T Pending DE280571T1 (de) 1987-02-27 1988-02-26 Matrix-zubereitungen mit verzoegerter freisetzung.
DE88301684T Expired - Lifetime DE3882739T2 (de) 1987-02-27 1988-02-26 Matrix-Zubereitungen mit verzögerter Freisetzung.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE198888301684T Pending DE280571T1 (de) 1987-02-27 1988-02-26 Matrix-zubereitungen mit verzoegerter freisetzung.

Country Status (26)

Country Link
EP (1) EP0280571B1 (de)
JP (1) JPH082793B2 (de)
KR (1) KR960005140B1 (de)
CN (1) CN1023765C (de)
AR (1) AR243376A1 (de)
AT (1) ATE92309T1 (de)
AU (1) AU604849B2 (de)
CA (1) CA1316110C (de)
CY (1) CY1741A (de)
DE (2) DE280571T1 (de)
DK (1) DK175620B1 (de)
EG (1) EG18523A (de)
ES (1) ES2044825T3 (de)
GR (1) GR930300027T1 (de)
HK (1) HK125793A (de)
HU (1) HU202747B (de)
IE (1) IE61419B1 (de)
IL (1) IL85538A (de)
LV (1) LV10184B (de)
MX (1) MX10558A (de)
NZ (1) NZ223619A (de)
PH (1) PH24358A (de)
PT (1) PT86831B (de)
RU (1) RU1831337C (de)
UA (1) UA18251A (de)
ZA (1) ZA881301B (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU210497B (en) * 1990-05-04 1995-04-28 Perio Prod Ltd Process for production of modified pectin
IL98087A (en) * 1990-05-04 1996-11-14 Perio Prod Ltd Preparation for dispensing drugs in the colon
FR2667242B1 (fr) * 1990-09-28 1994-11-25 Rhone Poulenc Sante Nouvelles formes orales a liberation prolongee avec un temps de latence au niveau stomacal amoindri.
IT1250654B (it) * 1991-07-08 1995-04-21 Farcon Ag Metodo per la preparazione di forme farmaceutiche orali a rilascio prolungato contenenti sostanze attive a solubilita' dipendente dal valore di ph.
WO1995011043A1 (fr) * 1993-10-22 1995-04-27 Tsumura & Co. Base pour preparation a liberation entretenue, preparation a liberation entretenue, et procede de production d'une telle preparation
US5695781A (en) * 1995-03-01 1997-12-09 Hallmark Pharmaceuticals, Inc. Sustained release formulation containing three different types of polymers
US5840332A (en) * 1996-01-18 1998-11-24 Perio Products Ltd. Gastrointestinal drug delivery system
WO1997042941A2 (en) 1996-05-13 1997-11-20 Novartis Consumer Health S.A. Buccal delivery system
CA2209868C (en) * 1997-08-15 2001-08-14 Bernard Charles Sherman Pharmaceutical compositions comprising cefuroxime axetil
WO1999044614A1 (en) * 1998-03-03 1999-09-10 Daewoong Pharmaceutical Co., Ltd. Pharmaceutical composition containing cefuroxime axetil stable for moisture absorption
KR100296413B1 (ko) * 1998-04-01 2001-11-14 김선진 세파클러함유서방성정제
AT413647B (de) 1998-11-26 2006-04-15 Sandoz Ag Verwendung eines copolymerisats aus 1-vinyl-2-pyrrolidon und vinylacetat zur herstellung von cefuroximaxetil-hältigen tabletten
EP1027885B1 (de) * 1999-02-09 2008-07-09 Pfizer Products Inc. Zusammensetzungen basischer Arzneistoffe mit verbesserter Bioverfügbarkeit
KR100647901B1 (ko) * 1999-07-09 2006-11-17 보령제약 주식회사 세파클러-함유 서방성 약제조성물 및 그의 제조방법
AT500063A1 (de) * 1999-11-23 2005-10-15 Sandoz Ag Beschichtete tablettenkerne
AU774993B2 (en) 1999-12-28 2004-07-15 Kimberly-Clark Worldwide, Inc. Use-dependent indicator system for absorbent articles
EP1255640B1 (de) 1999-12-28 2008-05-21 Kimberly-Clark Worldwide, Inc. Antimikrobielles wischtuch mit kontrollierter abgabe für harte oberflächen
US6372252B1 (en) * 2000-04-28 2002-04-16 Adams Laboratories, Inc. Guaifenesin sustained release formulation and tablets
US6419954B1 (en) * 2000-05-19 2002-07-16 Yamanouchi Pharmaceutical Co., Ltd. Tablets and methods for modified release of hydrophilic and other active agents
EP1330250B1 (de) 2000-10-30 2004-05-12 Lupin Limited Schnell zerfallende cefuroxim axetil enthaltende arzneizusammensetzung mit verzögerter wirkstoffabgabe
EP1589951B1 (de) * 2003-01-03 2017-08-09 Supernus Pharmaceuticals, Inc. Verwendung eines gemisches aus zwei oder mehr enterischen stoffen zur regulierung der arzneimittelfreisetzung über eine membran oder matrix für systemische therapeutika
DE102005019458A1 (de) 2005-04-25 2006-10-26 Grünenthal GmbH Darreichungsform mit verbesserter Freisetzung von Cefuroximaxetil
EP1837020A1 (de) * 2006-03-24 2007-09-26 Bioalliance Pharma Bioadhäsive Schleimhautträger zur langsamen Verabreichung von aktiven Substanzen
DE602007012236D1 (de) 2006-04-26 2011-03-10 Supernus Pharmaceuticals Inc Oxcarbazepin-zubereitungen für kontrollierte freisetzung mit sigmoidalem freisetzungsprofil
JP5245175B2 (ja) * 2006-11-13 2013-07-24 杏林製薬株式会社 持続放出型錠剤の製造方法
CA2756428A1 (en) 2009-03-27 2010-09-30 Mamoru Fukuda Matrix-type sustained release preparation containing basic additive
US20120040008A1 (en) * 2010-08-11 2012-02-16 Ashish Chatterji Pharmaceutical compositions of metabotropic glutamate 5 receptor (mglu5) antagonists
US20120039999A1 (en) * 2010-08-11 2012-02-16 Ashish Chatterji Pharmaceutical compositions of metabotropic glutamate 5 receptor (mglu5) antagonists
CN101912373B (zh) * 2010-08-24 2012-01-04 北京京丰制药有限公司 稳定的头孢克洛分散片及其制备方法
KR20170015315A (ko) * 2014-06-10 2017-02-08 라이온 가부시키가이샤 청주 효모를 함유하는 정제
JP7426685B2 (ja) * 2018-06-14 2024-02-02 株式会社東洋新薬 錠剤

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN151913B (de) * 1980-01-11 1983-09-03 Boots Co Ltd
JPS6024765B2 (ja) * 1981-11-27 1985-06-14 辰巳化学株式会社 セフアレキシンの持続性製剤の製造方法
JPS601128A (ja) * 1983-06-15 1985-01-07 Shionogi & Co Ltd 作用持続型セフアクロル製剤
LU85058A1 (fr) * 1983-10-24 1985-06-19 Pharlyse Comprimes pharmaceutiques a liberation prolongee,leur preparation et leur utilisation
US4520009A (en) * 1983-11-28 1985-05-28 Verex Laboratories, Inc. Sustained released aspirin formulation
US4680323A (en) * 1983-12-01 1987-07-14 Hans Lowey Method and composition for the preparation of controlled long-acting pharmaceuticals for oral administration
JPS61286330A (ja) * 1985-06-11 1986-12-16 Teijin Ltd 経口徐放性製剤
JPS62120315A (ja) * 1985-11-20 1987-06-01 Shin Etsu Chem Co Ltd 経口投与型徐放性錠剤の製造方法

Also Published As

Publication number Publication date
EP0280571A2 (de) 1988-08-31
EP0280571A3 (en) 1989-01-04
DK98088D0 (da) 1988-02-25
AR243376A1 (es) 1993-08-31
LV10184A (lv) 1994-10-20
UA18251A (uk) 1997-12-25
CN88101062A (zh) 1988-09-07
ES2044825T1 (es) 1994-01-16
IE61419B1 (en) 1994-11-02
LV10184B (en) 1995-04-20
DK98088A (da) 1988-08-28
HUT46531A (en) 1988-11-28
CN1023765C (zh) 1994-02-16
CA1316110C (en) 1993-04-13
DK175620B1 (da) 2004-12-27
DE3882739T2 (de) 1994-02-17
NZ223619A (en) 1990-10-26
PT86831B (pt) 1992-05-29
EP0280571B1 (de) 1993-08-04
KR960005140B1 (ko) 1996-04-22
JPS63227519A (ja) 1988-09-21
JPH082793B2 (ja) 1996-01-17
GR930300027T1 (de) 1993-05-24
EG18523A (en) 1993-04-30
KR880009639A (ko) 1988-10-04
PT86831A (pt) 1988-03-01
PH24358A (en) 1990-06-13
IL85538A (en) 1991-09-16
AU1219388A (en) 1988-09-01
ATE92309T1 (de) 1993-08-15
DE280571T1 (de) 1993-08-12
ES2044825T3 (es) 1994-11-16
IL85538A0 (en) 1988-08-31
AU604849B2 (en) 1991-01-03
ZA881301B (en) 1989-10-25
IE880545L (en) 1988-08-27
RU1831337C (ru) 1993-07-30
MX10558A (es) 1993-11-01
CY1741A (en) 1995-02-17
HU202747B (en) 1991-04-29
HK125793A (en) 1993-11-19

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition