DE3878835D1 - Antibakterielle 9-deoxy-9a-allyl und propargyl-9a-aza-9a-homoerythromycin-a-derivate. - Google Patents

Antibakterielle 9-deoxy-9a-allyl und propargyl-9a-aza-9a-homoerythromycin-a-derivate.

Info

Publication number
DE3878835D1
DE3878835D1 DE8888310465T DE3878835T DE3878835D1 DE 3878835 D1 DE3878835 D1 DE 3878835D1 DE 8888310465 T DE8888310465 T DE 8888310465T DE 3878835 T DE3878835 T DE 3878835T DE 3878835 D1 DE3878835 D1 DE 3878835D1
Authority
DE
Germany
Prior art keywords
propargyl
allyl
antibacterial
homoerythromycin
aza
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888310465T
Other languages
English (en)
Other versions
DE3878835T2 (de
Inventor
Gene Michael Bright
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of DE3878835D1 publication Critical patent/DE3878835D1/de
Publication of DE3878835T2 publication Critical patent/DE3878835T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
DE8888310465T 1987-11-10 1988-11-07 Antibakterielle 9-deoxy-9a-allyl und propargyl-9a-aza-9a-homoerythromycin-a-derivate. Expired - Fee Related DE3878835T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1987/002938 WO1989004167A1 (en) 1987-11-10 1987-11-10 Antibacterial 9-deoxo-9a-allyl and propargyl-9a-aza-9a-homoerythromycin a derivatives

Publications (2)

Publication Number Publication Date
DE3878835D1 true DE3878835D1 (de) 1993-04-08
DE3878835T2 DE3878835T2 (de) 1993-06-09

Family

ID=22202658

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888310465T Expired - Fee Related DE3878835T2 (de) 1987-11-10 1988-11-07 Antibakterielle 9-deoxy-9a-allyl und propargyl-9a-aza-9a-homoerythromycin-a-derivate.

Country Status (24)

Country Link
EP (1) EP0316128B1 (de)
JP (1) JPH0631301B2 (de)
KR (1) KR900008676B1 (de)
CN (1) CN1018648B (de)
AT (1) ATE86259T1 (de)
AU (1) AU597194B2 (de)
CA (1) CA1323026C (de)
CS (1) CS272243B2 (de)
DD (1) DD275871A5 (de)
DE (1) DE3878835T2 (de)
DK (1) DK623888A (de)
ES (1) ES2053765T3 (de)
GR (1) GR3007218T3 (de)
IE (1) IE61282B1 (de)
IL (1) IL88280A (de)
MX (1) MX13723A (de)
MY (1) MY104109A (de)
NZ (1) NZ226907A (de)
PH (1) PH25188A (de)
PL (1) PL158151B1 (de)
PT (1) PT88957B (de)
WO (1) WO1989004167A1 (de)
YU (1) YU46708B (de)
ZA (1) ZA888364B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5912331A (en) * 1991-03-15 1999-06-15 Merck & Co., Inc. Process for the preparation of 9-deoxo-9(Z)-hydroxyiminoerythromycin A
US5985844A (en) * 1992-03-26 1999-11-16 Merck & Co., Inc. Homoerythromycin A derivatives modified at the 4"-and 8A-positions
US5189159A (en) * 1992-04-02 1993-02-23 Merck & Co., Inc. 8a-AZA-8a-homoerythromycin cyclic iminoethers
US5210235A (en) * 1992-08-26 1993-05-11 Merck & Co., Inc. Methods of elaborating erythromycin fragments into amine-containing fragments of azalide antibiotics
US5332807A (en) * 1993-04-14 1994-07-26 Merck & Co., Inc. Process of producing 8A- and 9A-azalide antibiotics
HRP970714B1 (en) * 1997-12-31 2003-08-31 Pliva Pharm & Chem Works Beta,beta-disubstituted derivatives of 9-deoxo-9a-n-ethenyl-9a-aza-9a-homoerythromycin a
HRP20020885B1 (en) 2002-11-11 2007-05-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. SUBSTITUTED 9a-N-{N'-[4-(SULFONYL)PHENYLCARBAMOYL]}DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHROMYCIN A AND 5-O-DESOZAMINYL-9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHRONOLIDE A
HRP20020991A2 (en) 2002-12-12 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. N"-Substituted 9a-N-(N'-carbamoyl-Gamma-aminopropyl), 9a-N-(N'? -thiocarbamoyl-Gamma-aminopropyl), 9a-N-(N'-((Beta-cyanoethyl)-N'-carbamoyl-Gamma? -aminopropyl) and 9a-N-(N'-(Beta-cyanoethyl)-N'-thiocarbamoyl-Gamma? -aminopropyl) derivatives of 9-de
CN103072186B (zh) * 2012-12-21 2015-04-01 山东大学 一种高阻尼性机床构件的精密成型方法
CN103669417B (zh) * 2013-12-17 2016-05-11 中国建筑第八工程局有限公司 预制地下室外墙接缝处环氧树脂水泥混凝土及其施工方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
US4464527A (en) * 1983-06-30 1984-08-07 Pfizer Inc. Antibacterial 9-deoxo-9a-alkyl-9a-aza-9a-homoerythromycin A derivatives and intermediates therefore
US4465674A (en) * 1983-09-06 1984-08-14 Pfizer Inc. Azahomoerythromycin D derivative and intermediates therefor

Also Published As

Publication number Publication date
ZA888364B (en) 1990-06-27
EP0316128B1 (de) 1993-03-03
GR3007218T3 (de) 1993-07-30
CS272243B2 (en) 1991-01-15
WO1989004167A1 (en) 1989-05-18
CS740288A2 (en) 1990-03-14
JPH01153632A (ja) 1989-06-15
JPH0631301B2 (ja) 1994-04-27
MX13723A (es) 1993-05-01
PH25188A (en) 1991-03-27
PT88957A (pt) 1988-12-01
IE883365L (en) 1989-05-10
YU46708B (sh) 1994-04-05
PL275690A1 (en) 1989-06-12
CN1038453A (zh) 1990-01-03
ATE86259T1 (de) 1993-03-15
KR900008676B1 (ko) 1990-11-26
DK623888D0 (da) 1988-11-09
DE3878835T2 (de) 1993-06-09
YU208788A (en) 1990-02-28
DD275871A5 (de) 1990-02-07
EP0316128A2 (de) 1989-05-17
NZ226907A (en) 1990-09-26
PT88957B (pt) 1993-02-26
CN1018648B (zh) 1992-10-14
PL158151B1 (en) 1992-08-31
CA1323026C (en) 1993-10-12
ES2053765T3 (es) 1994-08-01
AU597194B2 (en) 1990-05-24
EP0316128A3 (en) 1989-11-08
IL88280A0 (en) 1989-06-30
IE61282B1 (en) 1994-10-19
DK623888A (da) 1989-07-25
AU2496888A (en) 1989-05-11
MY104109A (en) 1993-12-31
KR890008136A (ko) 1989-07-10
IL88280A (en) 1993-08-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee