DE3872621D1 - - Google Patents

Info

Publication number
DE3872621D1
DE3872621D1 DE88307273T DE3872621T DE3872621D1 DE 3872621 D1 DE3872621 D1 DE 3872621D1 DE 88307273 T DE88307273 T DE 88307273T DE 3872621 T DE3872621 T DE 3872621T DE 3872621 D1 DE3872621 D1 DE 3872621D1
Authority
DE
Germany
Prior art keywords
ligand
sample
support
analyte
analytes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE88307273T
Other languages
English (en)
Other versions
DE3872621T2 (de
Inventor
Roger Philip Dorking Surrey Gb Ekins
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Multilyte Ltd
Original Assignee
Multilyte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10631410&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3872621(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from PCT/GB1987/000558 external-priority patent/WO1988001058A1/en
Application filed by Multilyte Ltd filed Critical Multilyte Ltd
Application granted granted Critical
Publication of DE3872621D1 publication Critical patent/DE3872621D1/de
Publication of DE3872621T2 publication Critical patent/DE3872621T2/de
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/973—Simultaneous determination of more than one analyte

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • External Artificial Organs (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
DE8888307273T 1987-08-06 1988-08-05 Nachweis von umgebenden konzentrationen mehrerer analyten. Ceased DE3872621T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/GB1987/000558 WO1988001058A1 (en) 1986-08-06 1987-08-06 Determination of analyte concentration using two labelling markers
GB888803000A GB8803000D0 (en) 1988-02-10 1988-02-10 Determination of ambient concentrations of several analytes

Publications (2)

Publication Number Publication Date
DE3872621D1 true DE3872621D1 (de) 1992-08-13
DE3872621T2 DE3872621T2 (de) 1993-02-18

Family

ID=10631410

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888307273T Ceased DE3872621T2 (de) 1987-08-06 1988-08-05 Nachweis von umgebenden konzentrationen mehrerer analyten.

Country Status (18)

Country Link
US (1) US5432099A (de)
EP (2) EP0375700A1 (de)
JP (1) JP2562194B2 (de)
KR (1) KR970007079B1 (de)
AT (1) ATE78101T1 (de)
AU (1) AU625052B2 (de)
BR (1) BR8807644A (de)
CA (1) CA1334278C (de)
DE (1) DE3872621T2 (de)
DK (1) DK164944C (de)
ES (1) ES2034245T3 (de)
FI (1) FI92110C (de)
GB (1) GB8803000D0 (de)
GR (1) GR3005905T3 (de)
HU (1) HU884720D0 (de)
NO (1) NO177205C (de)
WO (1) WO1989001157A1 (de)
ZA (1) ZA885825B (de)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5807755A (en) * 1987-08-06 1998-09-15 Multilyte Limited Determination of ambient concentrations of several analytes
GB8810400D0 (en) 1988-05-03 1988-06-08 Southern E Analysing polynucleotide sequences
US7811751B2 (en) 1988-05-03 2010-10-12 Oxford Gene Technology Limited Analysing polynucleotide sequences
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US6416952B1 (en) 1989-06-07 2002-07-09 Affymetrix, Inc. Photolithographic and other means for manufacturing arrays
US6551784B2 (en) 1989-06-07 2003-04-22 Affymetrix Inc Method of comparing nucleic acid sequences
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5800992A (en) 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US5656207A (en) * 1989-06-24 1997-08-12 Gen Probe Incorporated Detecting or quantifying multiple analytes using labelling techniques
WO1992010588A1 (en) * 1990-12-06 1992-06-25 Affymax Technologies N.V. Sequencing by hybridization of a target nucleic acid to a matrix of defined oligonucleotides
WO1993008472A1 (en) * 1991-10-15 1993-04-29 Multilyte Limited Binding assay employing labelled reagent
US6943034B1 (en) * 1991-11-22 2005-09-13 Affymetrix, Inc. Combinatorial strategies for polymer synthesis
US5395752A (en) * 1993-03-19 1995-03-07 Ciba Corning Diagnostics Corp. Long emission wavelength chemiluminescent compounds and their use in test assays
US6893816B1 (en) 1993-10-28 2005-05-17 Houston Advanced Research Center Microfabricated, flowthrough porous apparatus for discrete detection of binding reactions
GB9326450D0 (en) * 1993-12-24 1994-02-23 Multilyte Ltd Binding assay
GB9326451D0 (en) * 1993-12-24 1994-02-23 Multilyte Ltd Binding assay
US7625697B2 (en) 1994-06-17 2009-12-01 The Board Of Trustees Of The Leland Stanford Junior University Methods for constructing subarrays and subarrays made thereby
US6207369B1 (en) * 1995-03-10 2001-03-27 Meso Scale Technologies, Llc Multi-array, multi-specific electrochemiluminescence testing
US6416714B1 (en) * 1995-04-25 2002-07-09 Discovery Partners International, Inc. Remotely programmable matrices with memories
GB9602323D0 (en) * 1996-02-06 1996-04-03 Boehringer Mannheim Gmbh Materials and methods relating to binding assays
US5874216A (en) 1996-02-23 1999-02-23 Ensys Environmental Products, Inc. Indirect label assay device for detecting small molecules and method of use thereof
EP0904542B1 (de) * 1996-03-01 2005-06-29 Beckman Coulter, Inc. System zur gleichzeitigen durchführung von mehrfachligandenbindungstests
US6821707B2 (en) 1996-03-11 2004-11-23 Matsushita Electric Industrial Co., Ltd. Optical information recording medium, producing method thereof and method of recording/erasing/reproducing information
US6586193B2 (en) * 1996-04-25 2003-07-01 Genicon Sciences Corporation Analyte assay using particulate labels
AU736340B2 (en) 1996-04-25 2001-07-26 Genicon Sciences Corporation Analyte assay using particulate labels
WO1997043611A1 (en) * 1996-05-16 1997-11-20 Affymetrix, Inc. Systems and methods for detection of labeled materials
EP0874242B2 (de) * 1997-04-21 2009-06-03 Randox Laboratories Ltd. Vorrichtung und Apparat zur gleichzeitigen Detektion von mehreren Analyten
CZ297165B6 (cs) * 1997-04-21 2006-09-13 Randox Laboratories Ltd. A British Company Of Ardmore Zpusob výroby zarízení s pevnou fází k provádení multianalytních rozboru
DE19731465A1 (de) * 1997-07-22 1999-01-28 Boehringer Mannheim Gmbh Verwendung von Kontrollflächen zur Detektion von Störproben in einem Nachweisverfahren
JPH11134720A (ja) 1997-08-28 1999-05-21 Matsushita Electric Ind Co Ltd 光学的情報記録媒体及びその記録再生方法
US6343062B1 (en) 1997-09-26 2002-01-29 Matsushita Electric Industrial Co., Ltd Optical disk device and optical disk for recording and reproducing high-density signals
US7157234B2 (en) 1997-10-24 2007-01-02 Beckman Coulter, Inc. Detection of very low quantities of analyte bound to a solid phase
DE19748489A1 (de) 1997-11-03 1999-05-06 Roche Diagnostics Gmbh Polyethylenglykol-derivatisierte Biomoleküle und deren Verwendung in heterogenen Nachweisverfahren
US6242246B1 (en) * 1997-12-15 2001-06-05 Somalogic, Inc. Nucleic acid ligand diagnostic Biochip
US20070166741A1 (en) 1998-12-14 2007-07-19 Somalogic, Incorporated Multiplexed analyses of test samples
WO1999040434A1 (en) 1998-02-04 1999-08-12 Invitrogen Corporation Microarrays and uses therefor
US6576478B1 (en) * 1998-07-14 2003-06-10 Zyomyx, Inc. Microdevices for high-throughput screening of biomolecules
TW448443B (en) 1998-08-05 2001-08-01 Matsushita Electric Ind Co Ltd Optical information storage media and production method as well as the storage reproducing method and device
US7708945B1 (en) 1999-08-13 2010-05-04 Bayer Technology Services Gmbh Device and method for determining multiple analytes
US6623936B1 (en) 1999-09-24 2003-09-23 Imgenex Compositions and methods for improved detection and classification of neoplasms
JP2004511753A (ja) * 2000-05-04 2004-04-15 イエール　ユニバーシティー タンパク質活性のスクリーニング用タンパク質チップ
US20030138208A1 (en) * 2000-05-06 2003-07-24 Michael Pawlak Grating optical waveguide structure for multi-analyte determinations and the use thereof
AU2001274068A1 (en) * 2000-06-02 2001-12-11 Zeptosens Ag Kit and method for determining a plurality of analytes
US7354721B2 (en) 2000-09-22 2008-04-08 Clontech Laboratories, Inc. Highly sensitive proteomic analysis methods, and kits and systems for practicing the same
US20040058385A1 (en) * 2000-11-17 2004-03-25 Abel Andreas Peter Kit and method for determining multiple analytes, with provisions for refrencing the density of immobilised recognition elements
GB0102357D0 (en) 2001-01-30 2001-03-14 Randox Lab Ltd Imaging method
WO2002068932A2 (en) * 2001-02-23 2002-09-06 Genicon Sciences Corporation Methods for providing extended dynamic range in analyte assays
US20030013208A1 (en) * 2001-07-13 2003-01-16 Milagen, Inc. Information enhanced antibody arrays
US20040253596A1 (en) * 2001-08-27 2004-12-16 Michael Pawlak Bioanalytical recognition surface with optimized recognition element density
JP2005517456A (ja) * 2002-02-15 2005-06-16 ソマロジック・インコーポレーテッド 核酸リガンドによる標的結合を検出する方法および試薬
WO2003096018A2 (de) * 2002-05-13 2003-11-20 Zeptosens Ag Kit zur assay-entwicklung und für serien-analysen
US20040248323A1 (en) * 2003-06-09 2004-12-09 Protometrix, Inc. Methods for conducting assays for enzyme activity on protein microarrays
US20050079507A1 (en) * 2003-10-09 2005-04-14 Ye Fang Target evaluation using biological membrane arrays
US20050141843A1 (en) * 2003-12-31 2005-06-30 Invitrogen Corporation Waveguide comprising scattered light detectable particles
GB0409775D0 (en) * 2004-04-30 2004-06-09 Mabtech Ab Assay
GB0409771D0 (en) * 2004-04-30 2004-06-09 Mabtech Ab Assay
EP1626279B1 (de) * 2004-08-12 2008-04-16 Roche Diagnostics GmbH Verfahren zur Diagnose von Leberfibrose
EP1626280B1 (de) * 2004-08-12 2007-02-14 Roche Diagnostics GmbH Verfahren zur Diagnose von Leberfibrose.
GB0421838D0 (en) 2004-09-30 2004-11-03 Congenia S R L Cancer markers
DE102004052729A1 (de) * 2004-10-30 2006-05-04 Roche Diagnostics Gmbh Immunkomplex-spezifsicher Antikörper zur Reduktion des Nullwerts beim Nachweis von Antigen-spezifisch gebundenen Antikörpern einer bestimmten Immunglobulinklasse in Array-Testformaten
CA2850323A1 (en) 2004-11-12 2006-12-28 Asuragen, Inc. Methods and compositions involving mirna and mirna inhibitor molecules
AU2006239534B2 (en) * 2005-04-26 2012-05-31 Bayer Intellectual Property Gmbh Novel equipment and method for coating substrates for analyte detection by way of an affinity assay method
US20080311679A1 (en) * 2005-12-23 2008-12-18 Koninklijke Philips Electronics N.V. Biosensor Device
SI1994171T1 (sl) * 2006-01-17 2015-07-31 Somalogic, Inc. Multipleksirane analize testnih vzorcev
EP2145001A2 (de) 2006-09-19 2010-01-20 Asuragen, Inc. Von mir-15, mir-26, mir -31,mir -145, mir-147, mir-188, mir-215, mir-216 mir-331, mmu-mir-292-3p regulierte gene und stoffwechselwege als ziele für einen therapeutischen eingriff
US20110136099A1 (en) 2007-01-16 2011-06-09 Somalogic, Inc. Multiplexed Analyses of Test Samples
US7855054B2 (en) * 2007-01-16 2010-12-21 Somalogic, Inc. Multiplexed analyses of test samples
US8906700B2 (en) 2007-11-06 2014-12-09 Ambergen, Inc. Methods and compositions for phototransfer
US8304255B1 (en) 2008-02-11 2012-11-06 Access Medical Systems, Ltd. Immunoassay cuvettes
WO2012022774A1 (en) 2010-08-19 2012-02-23 Roche Diagnostics Gmbh An assay for measurement of antibodies binding to a therapeutic monoclonal antibody
GB201016403D0 (en) 2010-09-29 2010-11-10 Bath Ventures Novel interaction between staphylococcus aureus Sbi and C3d protiens
EP2970909A4 (de) 2013-03-15 2017-02-15 The University of Chicago Verfahren und zusammensetzungen in zusammenhang mit t-zell aktivität

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4292296A (en) * 1978-09-12 1981-09-29 Baxter Travenol Laboratories, Inc. Diagnostic method
AR231590A1 (es) * 1981-04-29 1984-12-28 Ciba Geigy Ag Dispositivo de analisis inmunologico y procedimiento para obtenerlo
EP0134215B1 (de) * 1982-08-27 1989-10-25 EKINS, Roger Philip Messung der analytkonzentration
US4591570A (en) * 1983-02-02 1986-05-27 Centocor, Inc. Matrix of antibody-coated spots for determination of antigens
GB8421318D0 (en) * 1984-08-22 1984-09-26 Ekins R P Potentiating antibodies/other macro-molecules
US5096807A (en) * 1985-03-06 1992-03-17 Murex Corporation Imaging immunoassay detection system with background compensation and its use
AU614935B2 (en) * 1986-08-06 1991-09-19 Multilyte Limited Determination of analyte concentration using two labelling markers

Also Published As

Publication number Publication date
DK29390A (da) 1990-04-05
BR8807644A (pt) 1990-08-07
DK164944B (da) 1992-09-14
FI92110C (fi) 1994-09-26
US5432099A (en) 1995-07-11
EP0304202A1 (de) 1989-02-22
EP0304202B1 (de) 1992-07-08
JPH03503081A (ja) 1991-07-11
NO900534L (no) 1990-02-05
ES2034245T3 (es) 1993-04-01
FI92110B (fi) 1994-06-15
DE3872621T2 (de) 1993-02-18
ATE78101T1 (de) 1992-07-15
AU2253488A (en) 1989-03-01
FI900557A0 (fi) 1990-02-05
KR890702033A (ko) 1989-12-22
KR970007079B1 (ko) 1997-05-02
GB8803000D0 (en) 1988-03-09
DK164944C (da) 1993-02-01
GR3005905T3 (de) 1993-06-07
EP0375700A1 (de) 1990-07-04
WO1989001157A1 (en) 1989-02-09
CA1334278C (en) 1995-02-07
HU884720D0 (en) 1990-09-28
NO900534D0 (no) 1990-02-05
DK29390D0 (da) 1990-02-05
AU625052B2 (en) 1992-07-02
NO177205B (no) 1995-04-24
NO177205C (no) 1995-08-02
ZA885825B (en) 1989-04-26
JP2562194B2 (ja) 1996-12-11

Similar Documents

Publication Publication Date Title
DE3872621D1 (de)
GR3003073T3 (en) Solid phase assay employing capillary flow
ATE140539T1 (de) Festphasen-system für ligand-rezeptor- bestimmungen
EP0361729A3 (de) Fühler und Messverfahren unter Benutzung von transversalen Oberflächenwellen
CA2177362A1 (en) Sensor device for sandwich assay
GR3005303T3 (de)
LV10538A (lv) Imunologiski saistamas vielas noteiksanas panemiens biologiska skidruma un diagnostikas lidzeklis
AU4926085A (en) Immunoassays for protein analytes, particularly HB A1c, involving sample denaturation
NO175657C (no) Fremgangsmåte for utförelse av en immunologisk bestemmelse av et antigen i en væskepröve samt reagens for bruk til dette
DE59409947D1 (de) Verringerung des Hook-Effekts in Immuntests mit teilchenförmigem Trägermaterial
IL65767A (en) Method for assaying antigenantibody reactions and reagent therefor
AU5752186A (en) Method for measuring free ligands in biological fluids, and assay for measuring same
MY106963A (en) Agglutination assay.
EP0375439A3 (de) Geminale Diphenyl-Derivate und ihre Verwendung in Immunotests
EP0173973A3 (de) Verfahren zur Bestimmung des thyroid-stimulierenden Hormons
EP0250119A3 (de) Atherosclerotischer anti-idiotypischer Antikörper, Immunotest und Reagenzien
NO881998L (no) Fremgangsmaate til kvantitativ bestemmelse av serumproteiner i kroppsvaesker og middel til gjennomfoering av fremgangsmaaten.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8310 Action for declaration of annulment
8311 Complete invalidation