DE3855449T2 - DNS-Klone von menschlichem Thrombomodulin - Google Patents
DNS-Klone von menschlichem ThrombomodulinInfo
- Publication number
- DE3855449T2 DE3855449T2 DE3855449T DE3855449T DE3855449T2 DE 3855449 T2 DE3855449 T2 DE 3855449T2 DE 3855449 T DE3855449 T DE 3855449T DE 3855449 T DE3855449 T DE 3855449T DE 3855449 T2 DE3855449 T2 DE 3855449T2
- Authority
- DE
- Germany
- Prior art keywords
- human thrombomodulin
- dna clones
- thrombomodulin
- human
- clones
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Revoked
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/7455—Thrombomodulin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/047,246 US4912207A (en) | 1987-05-06 | 1987-05-06 | DNA clone of human thrombomodulin and portions thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3855449D1 DE3855449D1 (de) | 1996-09-05 |
DE3855449T2 true DE3855449T2 (de) | 1997-01-23 |
Family
ID=21947884
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3855449T Revoked DE3855449T2 (de) | 1987-05-06 | 1988-05-05 | DNS-Klone von menschlichem Thrombomodulin |
Country Status (10)
Country | Link |
---|---|
US (1) | US4912207A (de) |
EP (1) | EP0290419B1 (de) |
JP (1) | JP2896143B2 (de) |
AT (1) | ATE140962T1 (de) |
AU (1) | AU608602B2 (de) |
CA (1) | CA1338470C (de) |
DE (1) | DE3855449T2 (de) |
ES (1) | ES2090018T3 (de) |
GR (1) | GR3021063T3 (de) |
ZA (1) | ZA883245B (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE180496T1 (de) * | 1987-01-08 | 1999-06-15 | Asahi Chemical Ind | Peptid zur beschleunigung der wirkung des proteins-c mit thrombin |
JPH0720997B2 (ja) * | 1988-08-29 | 1995-03-08 | 興和株式会社 | 新規なトロンビン結合性物質及びその製法 |
US5202421A (en) * | 1988-12-27 | 1993-04-13 | Mochida Pharmaceutical Co., Ltd. | Anticoagulant substance obtained from urine and process for the preparation thereof |
JPH04505554A (ja) * | 1989-02-17 | 1992-10-01 | コドン | 可溶性トロンボモジュリン類似体 |
US5256770A (en) * | 1990-04-09 | 1993-10-26 | Schering Ag | Oxidation resistant thrombomodulin analogs |
US6063763A (en) * | 1989-04-28 | 2000-05-16 | Schering Aktiengesellschaft | Protease-resistant thrombomodulin analogs |
EP0445304A4 (en) * | 1989-09-25 | 1992-10-07 | Asahi Kasei Kogyo Kabushiki Kaisha | Isolated, physiologically active human thrombomodulin polypeptide |
AU6528790A (en) * | 1989-10-18 | 1991-05-16 | Daiichi Pharmaceutical Co., Ltd. | Recombinant human thrombomodulin |
EP0489180A4 (en) * | 1990-06-27 | 1993-03-31 | Mochida Pharmaceutical Co., Ltd. | Anticoagulant polypeptides |
AU8723391A (en) * | 1990-08-15 | 1992-03-17 | Schering Aktiengesellschaft | Superior thrombomodulin analogs for pharmaceutical use |
JPH05310787A (ja) * | 1992-05-01 | 1993-11-22 | Asahi Chem Ind Co Ltd | 新規なポリペプチド |
US5583102A (en) * | 1993-12-03 | 1996-12-10 | University Of Iowa Research Foundation | Human thrombomodulin in wound healing |
US5639625A (en) * | 1994-09-26 | 1997-06-17 | Oklahoma Medical Research Foundation | Method for detecting antibodies to thrombomodulin in patients |
ES2281137T3 (es) | 1997-10-15 | 2007-09-16 | Asahi Kasei Pharma Corporation | Metodo para mantener la calidad de un preparado de inyeccion acuoso de trombomodulina durante su almacenamiento y transporte. |
CN1314915A (zh) * | 1998-06-30 | 2001-09-26 | 持田制药株式会社 | 新的糖链连接的凝血调节蛋白样肽 |
US7259253B2 (en) * | 1999-05-14 | 2007-08-21 | Quark Biotech, Inc. | Genes associated with mechanical stress, expression products therefrom, and uses thereof |
CA2447629A1 (en) * | 2001-05-25 | 2002-12-05 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw | The lectin-like domain of thrombomodulin and its therapeutic use |
US6706068B2 (en) | 2002-04-23 | 2004-03-16 | Bret A. Ferree | Artificial disc replacements with natural kinematics |
US7579000B2 (en) | 2002-05-01 | 2009-08-25 | Bayer Schering Pharma Ag | Tissue factor targeted antibodies as anticoagulants |
PT1549341E (pt) * | 2002-05-01 | 2009-05-29 | Bayer Schering Pharma Ag | Anticorpos dirigidos contra o factor tecidual como anticoagulantes |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE180496T1 (de) * | 1987-01-08 | 1999-06-15 | Asahi Chemical Ind | Peptid zur beschleunigung der wirkung des proteins-c mit thrombin |
DK299087D0 (da) * | 1987-06-12 | 1987-06-12 | Novo Industri As | Proteins and derivatives thereof |
-
1987
- 1987-05-06 US US07/047,246 patent/US4912207A/en not_active Expired - Lifetime
-
1988
- 1988-05-02 JP JP63109816A patent/JP2896143B2/ja not_active Expired - Fee Related
- 1988-05-05 DE DE3855449T patent/DE3855449T2/de not_active Revoked
- 1988-05-05 ES ES88870079T patent/ES2090018T3/es not_active Expired - Lifetime
- 1988-05-05 ZA ZA883245A patent/ZA883245B/xx unknown
- 1988-05-05 AT AT88870079T patent/ATE140962T1/de not_active IP Right Cessation
- 1988-05-05 EP EP88870079A patent/EP0290419B1/de not_active Revoked
- 1988-05-05 AU AU15629/88A patent/AU608602B2/en not_active Ceased
- 1988-05-05 CA CA000566048A patent/CA1338470C/en not_active Expired - Fee Related
-
1996
- 1996-09-18 GR GR960402431T patent/GR3021063T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
GR3021063T3 (en) | 1996-12-31 |
EP0290419B1 (de) | 1996-07-31 |
AU608602B2 (en) | 1991-04-11 |
ZA883245B (en) | 1989-02-22 |
JP2896143B2 (ja) | 1999-05-31 |
ATE140962T1 (de) | 1996-08-15 |
EP0290419A2 (de) | 1988-11-09 |
ES2090018T3 (es) | 1996-10-16 |
CA1338470C (en) | 1996-07-23 |
JPS63301791A (ja) | 1988-12-08 |
AU1562988A (en) | 1988-11-10 |
EP0290419A3 (en) | 1989-11-23 |
US4912207A (en) | 1990-03-27 |
DE3855449D1 (de) | 1996-09-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE3855449D1 (de) | DNS-Klone von menschlichem Thrombomodulin | |
ATE142258T1 (de) | Menschlicher gefässpermeabilitätsfaktor | |
DE3872495D1 (de) | Herstellung von 3,3,3-trifluoropropen. | |
DE3887625T2 (de) | Verfahren zur Herstellung von 1,1,1-Trifluorodichlorethan und von 1,1,1,2-Tetrafluorchlorethan. | |
DE3889393T2 (de) | Verfahren zur Herstellung von 2,2,6,6-Tetramethyl-4-piperidylaminen. | |
ATE58529T1 (de) | Verfahren zur herstellung von 2,2,6,6,-tetraalkyl-4-piperidylamine. | |
ATE60583T1 (de) | Verfahren zur herstellung von 2,2,6,6-tetraalkyl- 4-piperidylaminen. | |
ATE111439T1 (de) | Verfahren zur herstellung von levodopa. | |
DK627687D0 (da) | Hirudinvariant | |
ATE41773T1 (de) | 4,5-dihydro-4-oxo-2((2-transphenylcyclopropyl)amino>-3-furancarbonsaeuren und derivate davon. | |
DE68911257T2 (de) | Verfahren zur Herstellung von 2,6-Dimethylnaphthalin. | |
DE58901165D1 (de) | Verfahren zur herstellung von 2,4-dihydroxybenzoesaeure. | |
DE3888543D1 (de) | Zusammensetzungen zur herstellung von gasdurchlässigen kontaktlinsen. | |
DE68906465T2 (de) | Verfahren zur Herstellung von 2,3-Dimethoxy-5-Methylbenzochinon. | |
DE68914950T2 (de) | Aminsalze von 1,4,2-Oxazaphospholidin-2-alkoxy-2-oxid-4-essigsäuren. | |
ATE57912T1 (de) | Verfahren zur herstellung von anilinofumarat und 2,3-chinolindicarbonsaeure. | |
DE3881103T2 (de) | Verfahren zur Herstellung von 1,3,2-Oxazaphosphorinan. | |
DE68913685D1 (de) | Verfahren zur Herstellung von 2,2'-Bis-defla2-oxazolin. | |
DE3682046D1 (de) | Verfahren zur herstellung von 4,4'-stilbendialdehyden. | |
ATE53010T1 (de) | Verfahren zur herstellung von 2,2,-dibrom-3oxonitrilen. | |
ATE47824T1 (de) | Verfahren zur herstellung von stickstoffduengern. | |
ATE44526T1 (de) | Verfahren zur herstellung von benzoylharnstoffen. | |
ATE62024T1 (de) | Verfahren zur herstellung von stickstoffmonoxid. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent | ||
8331 | Complete revocation |