DE3852561D1 - Monoklonaler Antikörper, Hybridomen, ihre Herstellung und ihre Verwendung. - Google Patents
Monoklonaler Antikörper, Hybridomen, ihre Herstellung und ihre Verwendung.Info
- Publication number
- DE3852561D1 DE3852561D1 DE3852561T DE3852561T DE3852561D1 DE 3852561 D1 DE3852561 D1 DE 3852561D1 DE 3852561 T DE3852561 T DE 3852561T DE 3852561 T DE3852561 T DE 3852561T DE 3852561 D1 DE3852561 D1 DE 3852561D1
- Authority
- DE
- Germany
- Prior art keywords
- hybridomas
- production
- monoclonal antibodies
- bfgf
- monoclonal antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 210000004408 hybridoma Anatomy 0.000 title abstract 2
- 102000003974 Fibroblast growth factor 2 Human genes 0.000 abstract 4
- 108090000379 Fibroblast growth factor 2 Proteins 0.000 abstract 4
- 238000003556 assay Methods 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
- C07K14/503—Fibroblast growth factor [FGF] basic FGF [bFGF]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/55—IL-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4975987 | 1987-03-03 | ||
JP21159987 | 1987-08-26 | ||
JP63016260A JP2526965B2 (ja) | 1987-02-24 | 1988-01-26 | ムテイン,dnaおよびその用途 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3852561D1 true DE3852561D1 (de) | 1995-02-09 |
DE3852561T2 DE3852561T2 (de) | 1995-07-13 |
Family
ID=27281323
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3852561T Expired - Lifetime DE3852561T2 (de) | 1987-03-03 | 1988-03-01 | Monoklonaler Antikörper, Hybridomen, ihre Herstellung und ihre Verwendung. |
Country Status (4)
Country | Link |
---|---|
US (2) | US5478740A (de) |
EP (1) | EP0288687B1 (de) |
AT (1) | ATE116373T1 (de) |
DE (1) | DE3852561T2 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5981197A (en) * | 1987-02-24 | 1999-11-09 | Takeda Chemical Industries, Ltd. | Monoclonal antibody, hybridoma, their production and use thereof |
US5852177A (en) * | 1987-02-24 | 1998-12-22 | Takeda Chemical Industries, Ltd. | Basic fibroblast growth factor (bFGF) muteins |
WO1988010269A1 (en) * | 1987-06-18 | 1988-12-29 | Monash University | Growth factors |
EP0387777A3 (de) * | 1989-03-15 | 1992-01-02 | Takeda Chemical Industries, Ltd. | Verfahren zum Nachweis von FGF und zur Diagnose von Tumoren |
EP0420081A1 (de) * | 1989-09-26 | 1991-04-03 | Takeda Chemical Industries, Ltd. | Monoklonaler Antikörper gegen sauren FGF, seine Herstellung und Verwendung |
WO1991006668A1 (en) * | 1989-10-27 | 1991-05-16 | The Du Pont Merck Pharmaceutical Company | Monoclonal antibodies to basic fibroblast growth factor that inhibit its biological activity |
WO1991009875A1 (en) | 1989-12-28 | 1991-07-11 | Takeda Chemical Industries, Ltd. | Monoclonal antibody, hybridomas, their production and use |
DE69224983T2 (de) * | 1991-01-17 | 1998-07-30 | Univ Washington | Anti-wachstumsfaktor antikörper in der behandlung von gefässstenose |
US5492894A (en) * | 1991-03-21 | 1996-02-20 | The Procter & Gamble Company | Compositions for treating wrinkles comprising a peptide |
AU3141495A (en) * | 1994-08-01 | 1996-03-04 | Board Of Regents, The University Of Texas System | Methods and compositions for the expression of a bone and prostate derived growth factor |
WO2003087318A2 (en) * | 2002-04-08 | 2003-10-23 | Eugene Levin | Truncated 24 kda basic fibroblast growth factor |
JP2005071556A (ja) * | 2003-08-28 | 2005-03-17 | Renesas Technology Corp | 半導体記憶装置および半導体集積回路装置 |
WO2008111281A1 (ja) * | 2007-03-12 | 2008-09-18 | The University Of Tokushima | アレルギー疾患の判定方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0789936B2 (ja) * | 1985-09-12 | 1995-10-04 | サイオス ノバ インコーポレイテッド | 組換え繊維芽細胞成長因子 |
-
1988
- 1988-03-01 DE DE3852561T patent/DE3852561T2/de not_active Expired - Lifetime
- 1988-03-01 EP EP88103047A patent/EP0288687B1/de not_active Expired - Lifetime
- 1988-03-01 AT AT88103047T patent/ATE116373T1/de not_active IP Right Cessation
-
1992
- 1992-07-15 US US07/915,025 patent/US5478740A/en not_active Expired - Lifetime
-
1995
- 1995-12-05 US US08/567,748 patent/US5858779A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0288687A2 (de) | 1988-11-02 |
US5858779A (en) | 1999-01-12 |
ATE116373T1 (de) | 1995-01-15 |
US5478740A (en) | 1995-12-26 |
EP0288687B1 (de) | 1994-12-28 |
DE3852561T2 (de) | 1995-07-13 |
EP0288687A3 (en) | 1989-05-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |