DE3817603C2 - - Google Patents
Info
- Publication number
- DE3817603C2 DE3817603C2 DE3817603A DE3817603A DE3817603C2 DE 3817603 C2 DE3817603 C2 DE 3817603C2 DE 3817603 A DE3817603 A DE 3817603A DE 3817603 A DE3817603 A DE 3817603A DE 3817603 C2 DE3817603 C2 DE 3817603C2
- Authority
- DE
- Germany
- Prior art keywords
- blood
- heat exchanger
- connection
- patient
- temperature
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000008280 blood Substances 0.000 claims description 14
- 210000004369 blood Anatomy 0.000 claims description 14
- 238000009217 hyperthermia therapy Methods 0.000 claims description 3
- 230000036760 body temperature Effects 0.000 claims description 2
- 210000003462 vein Anatomy 0.000 claims description 2
- 210000001367 artery Anatomy 0.000 claims 1
- 230000001678 irradiating effect Effects 0.000 claims 1
- 230000005855 radiation Effects 0.000 claims 1
- 230000003115 biocidal effect Effects 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 206010001526 Air embolism Diseases 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 206010016717 Fistula Diseases 0.000 description 1
- 206010020843 Hyperthermia Diseases 0.000 description 1
- 241000011102 Thera Species 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000003890 fistula Effects 0.000 description 1
- 230000036031 hyperthermia Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
- 230000003442 weekly effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/369—Temperature treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3687—Chemical treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/05—General characteristics of the apparatus combined with other kinds of therapy
- A61M2205/051—General characteristics of the apparatus combined with other kinds of therapy with radiation therapy
- A61M2205/053—General characteristics of the apparatus combined with other kinds of therapy with radiation therapy ultraviolet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/36—General characteristics of the apparatus related to heating or cooling
- A61M2205/3606—General characteristics of the apparatus related to heating or cooling cooled
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/36—General characteristics of the apparatus related to heating or cooling
- A61M2205/366—General characteristics of the apparatus related to heating or cooling by liquid heat exchangers
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- External Artificial Organs (AREA)
Description
Die Erfindung geht aus von einer Vorrichtung nach dem Oberbegriff des Anspruchs 1, wie sie z. B. aus der Deutschen medizinischen Wochenschrift Nr. 108 (1983) S. 504 bis 509 bekannt ist.The invention is based on a device according to the preamble of claim 1 as z. B. from the German medical weekly No. 108 (1983) pp. 504 to 509 is known.
Die mit einem solchen Gerät durchführbare konventionelle Hyperthermie-Therapie gilt als anerkanntes medizinisches Heilverfahren, bei dem, genau wie mittels Kurzwelle oder Bädern nach Schlenz, eine thera peutisch erwünschte, partielle Erhöhung der Körper temperatur bewirkt wird, wodurch thermolabile Erreger bei verschied enen Infektionskrankheiten geschwächt oder abgetötet werden.The conventional hyperthermia therapy that can be carried out with such a device is considered to be recognized medical cure, which, just like by means of short waves or baths according to Schlenz, a thera partially desired increase of the body temperature is caused, whereby thermolabile pathogens at different infectious diseases weakened or killed will.
Eine derartige Hyperthermie-Therapie belastet jedoch in starkem Maße den gesamten Organismus, so daß es eine Anzahl von Kontraindikationen zu beachten galt, insbesondere viele Herz- und Kreislauferkrankungen, aber auch ver schiedene pathologische Veränderungen am Bewegungs- und Stütz apparat sowie einige Hauterkrankungen.Such hyperthermia therapy however, weighs heavily the whole organism, making it a number of Contraindications had to be considered, especially many cardiovascular diseases, but also ver various pathological changes in movement and support apparatus as well as some skin diseases.
Danach war es Aufgabe der Erfindung, die Vorrichtung nach dem Oberbegriff des Patentanspruchs 1 so weiterzuentwickeln, daß die Hyperthermie standardisiert und einfach durchgeführt werden kann und die thermische Belastung des Organismus gänzlich wegfällt so daß praktisch keine Kontraindikationen mehr bestehen. Des weiteren soll bei entsprechender Behandlungsdauer das Blut nicht nur partiell, sondern fast vollständig der thermischen Behandlung ausgesetzt werden.Afterwards it was the object of the invention develop the device according to the preamble of claim 1 so that the Hyperthermia standardized and easily performed can be and the thermal load the organism is completely eliminated so that practically none Contraindications exist more. Furthermore should with the appropriate duration of treatment, the blood does not only partially, but almost completely thermal Be suspended.
Diese Aufgabe wird mit der Vorrichtung nach dem Patenanspruch 1 gelöst.This task is performed with the device according to the Patent claim 1 solved.
Bei einer Ausgestaltung der Vorrichtung gemäß dem Anspruch 2 kann das Blut gleich zeitig extrakorporal uv-bestrahlt werden, was die Behandlung zu einer Art "physikalischem Antibiotikum" ohne unumgänglich Neben- und Wechselwirkungen eines chemischen Antibiotikums werden läßt.In an embodiment of the device according to the Claim 2 can be the same blood be extracorporeally UV-irradiated at an early stage, Treatment for a kind of "physical antibiotic" without inevitable side effects and interactions chemical antibiotic.
Im folgenden wird die Vorrichtung an Hand der Zeichnung näher beschrieben.In the following the device is shown on the Drawing described in more detail.
Die Verbindung zwischen Gerät und Patient wird ent weder durch sie sog. Cimino-Fistel (Shunt zw. Art. radialis und V. cephalica antebrachii) oder über beide Arme (links an Art. radialis, rechts an Cubitalvene) hergestellt. Bei Eintritt in das Gerät wird das Blut heparinisiert und durchläuft eine Blutpumpe, wobei die Durchlaufmenge nicht über 15 ml/min liegen darf. Das Blut durchläuft in einer Kunststoff-Schlauchspirale den Wärmetauscher A, dessen Thermiköl-Füllung mittels der durch den Temperatur fühler und Schaltthermostat A gesteuerten Heizspirale A regelbar auf 40-47 Grad C erwärmt wird. Im Anschluß an diese Erwärmung durchläuft das Blut zur Temperatur- Rückführung den Wärmetauscher B, dessen über den Tem peraturfühler und Schaltthermostat B gesteuerte Heiz spirale das Thermiköl auf 37-38 Grad C erwärmt. Dieser Wärmetauscher B wird getrennt schaltbar sein, falls eine Senkung der Temperatur auf die physio logischen Normalwerte therapeutisch unzweckmäßig ist. Ein nachgeschalteter elektronischer Thermostat mit elektromagnetischem Absperrventil gewährleistet, daß auch bei Ausfall einer der vorgeschalteten Tempera turfühler u./o. Schaltthermostate kein übermäßig er wärmtes Blut zurückgeführt wird. Das Blut wird weiter durch einen Flachbehälter geführt, der bei entprechen der Indikation mit UV-Licht bestrahlt werden kann; der Flachbehälter dient hierbei zur Vergrößerung der Bestrahlungsfläche. Danach ist ein handelsüblicher Luftfänger mit Ventil geschaltet, der der Vermeidung von Lufteinschlüssen im Blut dient und somit der Gefahr einer Luftembolie wirksam vorbeugt. Eine weitere, danach geschaltete Vorrichtung ermöglicht vor der Reinfusion die Einleitung von Medikamenten, O₂ oder zur Volumensubstitution über einen handelsüblichen Luer-Anschluß.The connection between the device and the patient is released neither through them so-called Cimino fistula (shunt between Art. radialis and V. cephalica antebrachii) or over both arms (left on art. radialis, right on cubital vein). When entering the The device is heparinized and goes through one Blood pump, the flow rate not exceeding 15 ml / min. The blood runs through one Plastic hose spiral the heat exchanger A, whose Thermal oil filling by means of temperature sensor and switching thermostat A controlled heating coil A adjustable to 40-47 degrees C. In connection at this warming the blood passes through to the temperature Return the heat exchanger B, whose over the tem temperature sensor and switching thermostat B controlled heating spiral the thermal oil heated to 37-38 degrees C. This heat exchanger B will be switchable separately, if a drop in temperature to the physio logical normal values is therapeutically inappropriate. A downstream electronic thermostat with electromagnetic shut-off valve ensures that even if one of the upstream tempera fails door sensor u./o. Switching thermostats no excessive warmed blood is returned. The blood continues to grow passed through a flat container that match at the indication can be irradiated with UV light; the flat container serves to enlarge the Irradiation area. After that is a commercial one Air catcher switched with valve, the avoidance of air pockets in the blood and thus the danger effectively prevents air embolism. Another, then switched device allows before Reinfusion the introduction of medication, O₂ or for volume substitution via a commercially available Luer connector.
Claims (3)
- - einem Anschluß der Vorrichtung an eine Arterie des Patienten zum Entnehmen von Blut,
- - einem Wärmetauscher zum Ändern der Temperatur des Bluts auf einen therapeutisch wirksamen Wert,
- - einer Blutpumpe,
- - und einem Anschluß der Vorrichtung an eine Vene des Patienten zum Rückführen des Bluts,
- a connection of the device to an artery of the patient for taking blood,
- a heat exchanger for changing the temperature of the blood to a therapeutically effective value,
- - a blood pump,
- and a connection of the device to a vein of the patient for returning the blood,
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3817603A DE3817603A1 (en) | 1988-05-24 | 1988-05-24 | Extracorporeal hyperthermia device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3817603A DE3817603A1 (en) | 1988-05-24 | 1988-05-24 | Extracorporeal hyperthermia device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE3817603A1 DE3817603A1 (en) | 1989-11-30 |
| DE3817603C2 true DE3817603C2 (en) | 1992-12-24 |
Family
ID=6355005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE3817603A Granted DE3817603A1 (en) | 1988-05-24 | 1988-05-24 | Extracorporeal hyperthermia device |
Country Status (1)
| Country | Link |
|---|---|
| DE (1) | DE3817603A1 (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT3279B (en) | 1993-05-19 | 1995-05-25 | Kanapenas Rimantas Mykolas | Apparatus for purification of biological fluid from toxical material and virus |
| US5588959A (en) * | 1994-08-09 | 1996-12-31 | University Of Washington | Hemodialysis recirculation measuring method |
| WO1996009843A1 (en) * | 1994-09-26 | 1996-04-04 | Microwave Medical Systems, Inc. | Heat treatment for viral inactivation |
| DE19531935A1 (en) * | 1995-08-17 | 1997-02-20 | Panagiotis Tsolkas | Device for whole body hyperthermia treatment |
| DE19541783C1 (en) * | 1995-11-09 | 1997-03-27 | Fresenius Ag | Method for operating a blood treatment device for determining hemodynamic parameters during an extracorporeal blood treatment and device for determining hemodynamic parameters during an extracorporeal blood treatment |
| US5954659A (en) * | 1996-02-16 | 1999-09-21 | Curley; Michael G. | Method and apparatus for invasively measuring cardiac output by detecting temperature differences of blood heated by radiation |
| DE29719537U1 (en) * | 1997-11-04 | 1997-12-18 | Jostra Medizintechnik AG, 72145 Hirrlingen | Temperature regulating device |
| US20030095890A1 (en) | 2001-09-24 | 2003-05-22 | Shirley Miekka | Methods for sterilizing biological materials containing non-aqueous solvents |
| US6908591B2 (en) * | 2002-07-18 | 2005-06-21 | Clearant, Inc. | Methods for sterilizing biological materials by irradiation over a temperature gradient |
| LT5397B (en) | 2005-03-23 | 2007-01-25 | Rimantas KANAPĖNAS | Mini multipurpose medical laser apparatus |
| LT5996B (en) | 2012-06-21 | 2014-02-25 | Mykolas Rimantas KANAPĖNAS | Portable laser device for treatment |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4181132A (en) * | 1977-05-31 | 1980-01-01 | Parks Leon C | Method and apparatus for effecting hyperthermic treatment |
| DD247846A1 (en) * | 1983-11-23 | 1987-07-22 | Ilmenau Tech Hochschule | DEVICE FOR THERAPEUTICALLY EFFECTIVE ULTRAVIOLET RADIATION HEPARINIZED BLOOD |
| DE8500311U1 (en) * | 1985-01-08 | 1986-05-07 | Niens, Werner, 3394 Langelsheim | Cell made of quartz glass or other material permeable to UV light for irradiation and treatment of blood and other body fluids of humans and animals |
-
1988
- 1988-05-24 DE DE3817603A patent/DE3817603A1/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DE3817603A1 (en) | 1989-11-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP3573534B1 (en) | Apparatus for identifying and manipulating a blood vessel, and corresponding method | |
| DE3817603C2 (en) | ||
| DE60023352T2 (en) | INTERRUPTION FREE FLOW PUMPING DEVICE AND METHOD | |
| DE60000728T2 (en) | DEVICE FOR HEATING IV LIQUID WITH DETECTION OF PRESENCE AND ALIGNMENT OF A CASSETTE | |
| DE69922931T2 (en) | SYSTEM FOR HEAT CONTROL OF A LIVING BODY | |
| DE602004011981T2 (en) | DEVICE FOR CARRYING OUT PERITONEAL DIALYSIS TREATMENT | |
| DE60032491T2 (en) | HEAT EXCHANGERS WITH DISCRETE HEAT EXCHANGERS | |
| DE69331641T2 (en) | CONNECTION DEVICE | |
| US5391142A (en) | Apparatus and method for the extracorporeal treatment of the blood of a patient having a medical condition | |
| DE60127942T2 (en) | DISPOSABLE CASSETTE FOR INTRAVASCULAR HEAT EXCHANGE CATHETERS | |
| CH646063A5 (en) | DEVICE FOR CARRYING OUT A FEVER TREATMENT. | |
| DE69406118T2 (en) | BALLOON CATHETER AND DEVICE FOR PERFUSION WITH THE BALLOON CATHETER | |
| US4787883A (en) | Extracorporal thermo-therapy device and method for curing diseases | |
| Rohde et al. | Four-year experience with the routine use of the programmable Hakim valve in the management of children with hydrocephalus | |
| EP2533827B1 (en) | Device and method for monitoring a vascular access for an extracorporeal blood treatment | |
| DE19531935A1 (en) | Device for whole body hyperthermia treatment | |
| DE1914724U (en) | ORTHOPEDIC DEVICE FOR CALMING AND STRETCHING THE Cervical Vertebrae. | |
| EP0659444B1 (en) | Apparatus for pumping blood | |
| DE60127812T2 (en) | HEAT EXCHANGING CATHETERS WITH SEVERAL LUMENS | |
| EP3723595A1 (en) | Method and apparatus for acquiring the body temperature of a patient | |
| CH615588A5 (en) | Device for the treatment of sensitive liquids, especially of blood | |
| DE69408765T2 (en) | Infusion device | |
| DE2948059A1 (en) | Scalp blood circulation interruption device for hair loss prevention - comprises pressure band placed around head coupled to pressurised air source | |
| DE69519419T2 (en) | Manufacturing method for a blood transfusion device | |
| DE69118381T2 (en) | INFLATABLE CLOTHING TO PRESS OR INFLATABLE MATTRESS |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OM8 | Search report available as to paragraph 43 lit. 1 sentence 1 patent law | ||
| 8110 | Request for examination paragraph 44 | ||
| 8127 | New person/name/address of the applicant |
Owner name: STIEGLITZ, MICHAEL, 6473 GEDERN, DE |
|
| D2 | Grant after examination | ||
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |