DE3789833T2 - Isoliertes Phenylalanindehydrogenase-Gen und Verfahren zur Herstellung von Phenylalanindeshydrogenase. - Google Patents

Isoliertes Phenylalanindehydrogenase-Gen und Verfahren zur Herstellung von Phenylalanindeshydrogenase.

Info

Publication number
DE3789833T2
DE3789833T2 DE3789833T DE3789833T DE3789833T2 DE 3789833 T2 DE3789833 T2 DE 3789833T2 DE 3789833 T DE3789833 T DE 3789833T DE 3789833 T DE3789833 T DE 3789833T DE 3789833 T2 DE3789833 T2 DE 3789833T2
Authority
DE
Germany
Prior art keywords
phenylalanine dehydrogenase
isolated
producing
gene
dehydrogenase gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3789833T
Other languages
English (en)
Other versions
DE3789833D1 (de
Inventor
Yasuo Hibino
Yasuhisa Asano
Noriko Okazaki
Naganori Numao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Central Glass Co Ltd
Sagami Chemical Research Institute
Tosoh Corp
Original Assignee
Central Glass Co Ltd
Sagami Chemical Research Institute
Tosoh Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP61280654A external-priority patent/JPS63157986A/ja
Application filed by Central Glass Co Ltd, Sagami Chemical Research Institute, Tosoh Corp filed Critical Central Glass Co Ltd
Publication of DE3789833D1 publication Critical patent/DE3789833D1/de
Application granted granted Critical
Publication of DE3789833T2 publication Critical patent/DE3789833T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0016—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1)
    • C12N9/0018—Phenylalanine dehydrogenase (1.4.1.20)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0026—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5)
    • C12N9/0028—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5) with NAD or NADP as acceptor (1.5.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/222—Phenylalanine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
DE3789833T 1986-08-12 1987-08-12 Isoliertes Phenylalanindehydrogenase-Gen und Verfahren zur Herstellung von Phenylalanindeshydrogenase. Expired - Fee Related DE3789833T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP18785286 1986-08-12
JP61280654A JPS63157986A (ja) 1986-08-12 1986-11-27 遺伝子組換によるｌ−フエニルアラニンの製造方法

Publications (2)

Publication Number Publication Date
DE3789833D1 DE3789833D1 (de) 1994-06-23
DE3789833T2 true DE3789833T2 (de) 1994-09-01

Family

ID=26504605

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3789833T Expired - Fee Related DE3789833T2 (de) 1986-08-12 1987-08-12 Isoliertes Phenylalanindehydrogenase-Gen und Verfahren zur Herstellung von Phenylalanindeshydrogenase.

Country Status (3)

Country Link
US (2) US4970157A (de)
EP (1) EP0256514B1 (de)
DE (1) DE3789833T2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0806482A3 (de) * 1992-03-17 1998-01-28 Unitika Ltd. Verfahren und Reagenz zur enzymatischen Analyse
GB9321764D0 (en) * 1993-10-21 1993-12-15 Health Lab Service Board Phenylalanine dehydrogenase production
JP3716427B2 (ja) * 1994-06-14 2005-11-16 味の素株式会社 α−ケトグルタル酸デヒドロゲナーゼ遺伝子
US6358714B1 (en) * 1995-04-03 2002-03-19 The Nutrasweet Company Materials and methods for the production of D-phenylalanine
US5851810A (en) * 1995-06-05 1998-12-22 Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University Nucleic acid encoding rhodococcus phenylalanine dehydrogenase
US6468781B1 (en) * 1999-07-08 2002-10-22 Bristol-Myers Squibb Company Stereoselective reductive amination of ketones
JP2002330763A (ja) * 2001-05-02 2002-11-19 Ajinomoto Co Inc 発酵法による目的物質の製造法
US8003367B2 (en) * 2004-03-16 2011-08-23 Ajinomoto Co., Inc. Method for producing L-amino acids by fermentation using bacteria having enhanced expression of xylose utilization genes
WO2006015885A1 (en) * 2004-08-13 2006-02-16 University College Dublin, National University Of Ireland, Dublin Amino acid dehydrogenase-derived biocatalysts
EP1918375B1 (de) * 2005-08-02 2015-03-11 Kaneka Corporation D-aminosäure-oxidase und verfahren zur herstellung von l-aminosäure, 2-oxosäure oder cyclischem imin
PE20080168A1 (es) * 2006-03-23 2008-02-25 Bristol Myers Squibb Co Preparacion enzimatica de (s)-aminoacido a partir del (r,s)-aminoacido o a partir del ceto acido
US9273332B2 (en) 2006-10-12 2016-03-01 Kaneka Corporation Method for production of L-amino acid
JPWO2010067578A1 (ja) 2008-12-09 2012-05-17 株式会社カネカ 新規なアミノ酸脱水素酵素、およびｌ−アミノ酸、２−オキソ酸、又はｄ−アミノ酸の製造方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS561890A (en) * 1979-06-15 1981-01-10 Ajinomoto Co Inc Preparation of l-phenylalanine by fermentation
JPS58134994A (ja) * 1982-02-05 1983-08-11 Ajinomoto Co Inc 発酵法によるｌ−フエニルアラニンの製造法
JPH0732710B2 (ja) * 1983-05-28 1995-04-12 協和醗酵工業株式会社 フエニ−ルアラニンの製造法
DE3307095A1 (de) * 1983-03-01 1984-09-06 Degussa Ag, 6000 Frankfurt Mikrobiologisch hergestellte l-phenylalanin-dehydrogenase, verfahren zu ihrer gewinnung und ihre verwendung
EP0137646A1 (de) * 1983-08-16 1985-04-17 Genentech, Inc. Rekombinantes Verfahren zur Herstellung von L-Aminosäuren, rekombinante Expressionsvektoren und transformierte Mikroorganismen zur Verwendung in diesem Verfahren
JPS6066984A (ja) * 1983-09-22 1985-04-17 Ajinomoto Co Inc 発酵法によるｌ−フェニルアラニンの製造法
JPS60160890A (ja) * 1984-01-30 1985-08-22 Kyowa Hakko Kogyo Co Ltd Ｌ−フエニルアラニンの製造法
JPS60164493A (ja) * 1984-02-08 1985-08-27 Kyowa Hakko Kogyo Co Ltd Ｌ−フェニルアラニンの製造法
US4849345A (en) * 1985-04-17 1989-07-18 Sagami Chemical Research Center L-phenylalanine dehydrogenase and use thereof
FR2583432B1 (fr) * 1985-06-13 1988-11-04 Inst Francais Du Petrole Procede de production enzymatique de l-a-aminoacides a partir d'a-cetoacides
EP0212972A3 (de) * 1985-08-20 1988-10-05 Allelix Inc. Verfahren zur biologischen Umwandlung

Also Published As

Publication number Publication date
DE3789833D1 (de) 1994-06-23
EP0256514B1 (de) 1994-05-18
EP0256514A3 (en) 1989-03-15
US4970157A (en) 1990-11-13
EP0256514A2 (de) 1988-02-24
US5015582A (en) 1991-05-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee