DE3786174T2 - Weiche steroide mit anti-entzündungswirkung. - Google Patents

Weiche steroide mit anti-entzündungswirkung.

Info

Publication number
DE3786174T2
DE3786174T2 DE87907186T DE3786174T DE3786174T2 DE 3786174 T2 DE3786174 T2 DE 3786174T2 DE 87907186 T DE87907186 T DE 87907186T DE 3786174 T DE3786174 T DE 3786174T DE 3786174 T2 DE3786174 T2 DE 3786174T2
Authority
DE
Germany
Prior art keywords
beta
agents
hydroxyandrost
alkoxy
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE87907186T
Other languages
English (en)
Other versions
DE3786174D1 (de
Inventor
Nicholas S Bodor
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of DE3786174D1 publication Critical patent/DE3786174D1/de
Application granted granted Critical
Publication of DE3786174T2 publication Critical patent/DE3786174T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/006—Ketals at position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
DE87907186T 1987-10-13 1987-10-13 Weiche steroide mit anti-entzündungswirkung. Expired - Fee Related DE3786174T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP87907186A EP0334853B1 (de) 1987-10-13 1987-10-13 Weiche steroide mit anti-entzündungswirkung
PCT/US1987/002590 WO1989003390A1 (en) 1987-10-13 1987-10-13 Soft steroids having anti-inflammatory activity

Publications (2)

Publication Number Publication Date
DE3786174D1 DE3786174D1 (de) 1993-07-15
DE3786174T2 true DE3786174T2 (de) 1993-10-21

Family

ID=22202600

Family Applications (1)

Application Number Title Priority Date Filing Date
DE87907186T Expired - Fee Related DE3786174T2 (de) 1987-10-13 1987-10-13 Weiche steroide mit anti-entzündungswirkung.

Country Status (4)

Country Link
EP (1) EP0334853B1 (de)
AT (1) ATE90355T1 (de)
DE (1) DE3786174T2 (de)
WO (1) WO1989003390A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4018168A1 (de) * 1990-06-01 1991-12-05 Schering Ag Ausgangsverbindungen fuer die herstellung von 10ss-h-steroiden und ein verfahren zur herstellung dieser ausgangsverbindungen
US6777399B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
GB0019172D0 (en) 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
US6858596B2 (en) 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
CO5310534A1 (es) 2000-08-05 2003-08-29 Glaxo Group Ltd Nuevos derivados de androstano anti-inflamatorios
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
US20040138187A1 (en) * 2002-08-28 2004-07-15 Reading Christopher L. Therapeutic treatment methods
GB0316290D0 (en) 2003-07-11 2003-08-13 Glaxo Group Ltd Novel compounds
CN100450488C (zh) * 2003-11-03 2009-01-14 诺顿·希尔思凯尔有限公司 用于干粉吸入剂的软类固醇组合物
US7579335B2 (en) 2005-01-10 2009-08-25 Glaxo Group Limited Androstane 17α-carbonate derivatives for use in the treatment of allergic and inflammatory conditions
PT105723B (pt) * 2011-05-26 2014-03-24 Hovione Farmaci Ncia S A Método para a preparação de compostos orgânicos biologicamente activos
US8900626B2 (en) 2011-06-20 2014-12-02 Senju Usa, Inc. Transdermal drug delivery system and method of using the same
US20150376225A1 (en) * 2013-01-23 2015-12-31 Sphaera Pharma Pvtd. Ltd. Novel compounds of 11beta-hydroxy-steroids for use in mitochondria biogenesis and diseases associated with mitochondrial dysfunction or depletion
WO2016013030A2 (en) 2014-07-23 2016-01-28 Sphaera Pharma Pvt. Ltd. Hydroxysteroid compounds, their intermediates, process of preparation, composition and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3558675A (en) * 1969-06-30 1971-01-26 Merck & Co Inc Steroid carbonates and process
GB1438940A (en) * 1972-07-19 1976-06-09 Glaxo Lab Ltd 17beta-haloalkoxycarbonyl-17alpha-oxysteroids
US4093721A (en) * 1974-08-30 1978-06-06 Glaxo Laboratories Limited Pharmaceutical compositions of 6α,9α-difluoro-androst-4-ene-17β-carboxylates and derivatives thereof
US4263289A (en) * 1978-04-05 1981-04-21 Syntex (U.S.A.) Inc. Thio etianic acid derivatives
SE449106B (sv) * 1980-07-10 1987-04-06 Otsuka Pharma Co Ltd Steroid med anti-inflammatorisk verkan samt komposition innehallande denna

Also Published As

Publication number Publication date
DE3786174D1 (de) 1993-07-15
ATE90355T1 (de) 1993-06-15
EP0334853B1 (de) 1993-06-09
EP0334853A1 (de) 1989-10-04
EP0334853A4 (de) 1990-02-26
WO1989003390A1 (en) 1989-04-20

Similar Documents

Publication Publication Date Title
DE3786174T2 (de) Weiche steroide mit anti-entzündungswirkung.
OA07116A (fr) Esters aromatiques hétérocycliques de stéroïdes, leur préparation et compositions pharmaceutiques les contenant.
DK73594A (da) Fremgangsmåde til fremstilling af 17-substituerede 4-aza-5,7-androstadien-3-on-derivater
ATE79544T1 (de) Zusammensetzungen zur behandlung von hypercholesterinaemie.
ATE106867T1 (de) 13-trans-retinsäureester.
DK0606012T3 (da) Sammensætninger indeholdende cholesterylestere af umættede fedtsyrer
ES2059789T3 (es) Esteroides sustituidos con acido fosfinico como inhibidores de la esteroide-5 alfa-reductasa.
FR2421912A1 (fr) Derives d'acide thio-etianique, leur procede de production et medicament les contenant
AU618443B2 (en) The use of the active substance azelastine in combatting psoriasis disorders and inflammatory disorders
NO166939C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive carboxylsyrederivater.
PT90363A (pt) Metodo para o tratamento de doencas auto-imunes em mamiferos utilizando como agentes imunosupressores acidos 4-quinolinocarboxilicos e seus derivados
ZA899670B (en) Phosphonic acid substituted steroids as steroid 5-alpha-reductase inhibitors
IE802589L (en) Anti-inflammatory pharmaceutical composition containing¹rosmarinic acid
DE3468021D1 (en) Imidazol-2-yl mercapto alkanoic acids, process for producing the same and pharmaceutical preparations containing the same
DE69133077D1 (de) Herstellung von ST1435 enthaltenden pharmazeutischen Zusammensetzungen zur topischen Verwendung
SE7602279L (sv) Terpenoidestrar av steroider
ES2044170T3 (es) Sal de estroncio, su procedimiento de preparacion y las composiciones farmaceuticas que la contienen.
FR2561919B1 (fr) Composition pharmaceutique constituee d'une part, a titre de principe actif, par la 9a,11b-dichloro 16a-methyl 21-oxycarbonyldicyclohexyl methyloxy pregna-1,4-diene 3,20-dione et d'autre part, par un excipient pharmaceutique inerte apte a permettre l'action du produit dans le rectum ou le colon
PT86228A (de) Verfahren zur herstellung von 6alpha,9alpha-difluor-11beta,17alpha-dihydroxy-16alpha-methil-4-pregnen-3,20-dion und dessen derivate
DE3780105D1 (de) 13alpha-alkylgonan-delta9(11)-5,10-epoxide.
Maeda Studies on relations of temperature of topically used cortico-steroid hormone (beta-methasone) to its therapeutic effect Part I. Clinical investigation on acute otitis media cases
FI945119A0 (fi) Menetelmä 3(S)-metyyliheptaanihapon valmistamiseksi ja välituotteet
FR2598616B1 (fr) Composition pharmaceutique destinee au traitement des phenomenes d'inflammation chez les mammiferes
BE877242A (fr) Esters d'acides steroidaux (16 alpha, 17-beta)naphtaleno- et cyclohexene-21-carboxyliques, a proprietes anti-inflammatoires
IT8848445A0 (it) Composizione farmaceutica comprendente acido p-acetammidobenzoico e zidovudina per il trattamento dell'aids e sindromi correlate

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee