DE3752124T2 - Verfahren zur Herstellung von Penem Derivaten und Zwischenprodukte zu dieser Herstellung - Google Patents

Verfahren zur Herstellung von Penem Derivaten und Zwischenprodukte zu dieser Herstellung

Info

Publication number
DE3752124T2
DE3752124T2 DE3752124T DE3752124T DE3752124T2 DE 3752124 T2 DE3752124 T2 DE 3752124T2 DE 3752124 T DE3752124 T DE 3752124T DE 3752124 T DE3752124 T DE 3752124T DE 3752124 T2 DE3752124 T2 DE 3752124T2
Authority
DE
Germany
Prior art keywords
denotes
group
production
hydrogen atom
chem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3752124T
Other languages
English (en)
Other versions
DE3752124D1 (de
Inventor
Steven Coulton
John Barry Harbridge
Neal Frederick Osborne
Graham Walker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB868601119A external-priority patent/GB8601119D0/en
Priority claimed from GB868625017A external-priority patent/GB8625017D0/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of DE3752124D1 publication Critical patent/DE3752124D1/de
Application granted granted Critical
Publication of DE3752124T2 publication Critical patent/DE3752124T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568—Four-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Oscillators With Electromechanical Resonators (AREA)
  • Networks Using Active Elements (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Inks, Pencil-Leads, Or Crayons (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
DE3752124T 1986-01-17 1987-01-09 Verfahren zur Herstellung von Penem Derivaten und Zwischenprodukte zu dieser Herstellung Expired - Lifetime DE3752124T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868601119A GB8601119D0 (en) 1986-01-17 1986-01-17 Compounds & processes
GB868625017A GB8625017D0 (en) 1986-10-18 1986-10-18 Compounds & processes

Publications (2)

Publication Number Publication Date
DE3752124D1 DE3752124D1 (de) 1997-11-13
DE3752124T2 true DE3752124T2 (de) 1998-03-26

Family

ID=26290238

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3752124T Expired - Lifetime DE3752124T2 (de) 1986-01-17 1987-01-09 Verfahren zur Herstellung von Penem Derivaten und Zwischenprodukte zu dieser Herstellung

Country Status (14)

Country Link
EP (1) EP0232966B1 (de)
JP (2) JPH0798822B2 (de)
KR (1) KR880005138A (de)
AT (1) ATE159021T1 (de)
AU (3) AU607693B2 (de)
DE (1) DE3752124T2 (de)
DK (1) DK21287A (de)
FI (1) FI870176A (de)
HU (1) HU198725B (de)
MA (1) MA20852A1 (de)
NO (1) NO870176L (de)
NZ (1) NZ218950A (de)
PL (1) PL263657A1 (de)
PT (1) PT84117B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8711391D0 (en) * 1987-05-14 1987-06-17 Beecham Group Plc Process
DE3839987A1 (de) * 1988-11-26 1990-05-31 Hoechst Ag Penemderivate und verfahren zu ihrer herstellung
GB9116236D0 (en) * 1991-07-27 1991-09-11 Smithkline Beecham Plc Novel compounds
GB9307201D0 (en) * 1993-04-06 1993-05-26 Smithkline Beecham Plc Novel process
AR039774A1 (es) 2002-05-01 2005-03-02 Wyeth Corp 6-alquiliden-penems biciclicos como inhibidores de beta-lactamasas
AR039475A1 (es) 2002-05-01 2005-02-23 Wyeth Corp 6-alquiliden-penems triciclicos como inhibidores de beta-lactamasa
AR039476A1 (es) * 2002-05-01 2005-02-23 Wyeth Corp Proceso para preparar derivados de 6-alquiliden penem

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1368074A (en) * 1971-02-04 1974-09-25 Beecham Group Ltd Substituted beta-lactams and their preparation
DE2343497A1 (de) * 1972-06-22 1975-03-13 Hoechst Ag Verfahren zur herstellung von 4-mercapto-azetidinonen-(2)
EP0042026B1 (de) * 1978-02-02 1986-01-08 Ciba-Geigy Ag 3,4-Disubstituierte Azetidin-2-onverbindungen und Verfahren zu ihrer Herstellung
ZA81306B (en) * 1980-01-21 1982-02-24 Bristol Myers Co Chemical compounds
GB8321677D0 (en) * 1983-08-11 1983-09-14 Erba Farmitalia Preparation of penems
GB8402086D0 (en) * 1984-01-26 1984-02-29 Beecham Group Plc Compounds
GB8500831D0 (en) * 1985-01-14 1985-02-20 Erba Farmitalia Preparing azetidinone intermediates
GB8518422D0 (en) * 1985-07-22 1985-08-29 Beecham Group Plc Compounds

Also Published As

Publication number Publication date
FI870176A0 (fi) 1987-01-16
EP0232966A1 (de) 1987-08-19
MA20852A1 (fr) 1987-10-01
JPS62169792A (ja) 1987-07-25
AU607693B2 (en) 1991-03-14
PT84117A (en) 1987-02-01
KR880005138A (ko) 1988-06-28
AU7826891A (en) 1991-08-29
DK21287A (da) 1987-07-18
DE3752124D1 (de) 1997-11-13
AU7826791A (en) 1991-08-29
EP0232966B1 (de) 1997-10-08
JP2695137B2 (ja) 1997-12-24
AU6758687A (en) 1987-07-23
HUT45260A (en) 1988-06-28
NO870176L (no) 1987-07-20
NZ218950A (en) 1991-04-26
PT84117B (pt) 1989-07-31
DK21287D0 (da) 1987-01-15
ATE159021T1 (de) 1997-10-15
PL263657A1 (en) 1988-07-21
JPH08291139A (ja) 1996-11-05
HU198725B (en) 1989-11-28
JPH0798822B2 (ja) 1995-10-25
FI870176A (fi) 1987-07-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition