DE3751811T2 - Formulations containing LH-RH analogs - Google Patents
Formulations containing LH-RH analogsInfo
- Publication number
- DE3751811T2 DE3751811T2 DE3751811T DE3751811T DE3751811T2 DE 3751811 T2 DE3751811 T2 DE 3751811T2 DE 3751811 T DE3751811 T DE 3751811T DE 3751811 T DE3751811 T DE 3751811T DE 3751811 T2 DE3751811 T2 DE 3751811T2
- Authority
- DE
- Germany
- Prior art keywords
- analogs
- formulations containing
- relates
- aerosol formulations
- suspension aerosol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
Abstract
The invention relates to novel suspension aerosol formulations comprising LHRH analogs.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/934,874 US4851211A (en) | 1986-11-25 | 1986-11-25 | LHRH analog formulations |
US07/114,359 US4897256A (en) | 1986-11-25 | 1987-11-04 | LHRH analog formulations |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3751811D1 DE3751811D1 (en) | 1996-06-20 |
DE3751811T2 true DE3751811T2 (en) | 1996-11-28 |
Family
ID=26812097
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3751811T Expired - Fee Related DE3751811T2 (en) | 1986-11-25 | 1987-11-23 | Formulations containing LH-RH analogs |
DE87117226T Expired - Fee Related DE3785570T2 (en) | 1986-11-25 | 1987-11-23 | Compositions containing LHRH analogs. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE87117226T Expired - Fee Related DE3785570T2 (en) | 1986-11-25 | 1987-11-23 | Compositions containing LHRH analogs. |
Country Status (7)
Country | Link |
---|---|
US (1) | US4897256A (en) |
EP (2) | EP0510731B1 (en) |
JP (1) | JP2533586B2 (en) |
AT (1) | ATE137963T1 (en) |
CA (1) | CA1300009C (en) |
DE (2) | DE3751811T2 (en) |
ES (2) | ES2089301T3 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10214031A1 (en) * | 2002-03-27 | 2004-02-19 | Pharmatech Gmbh | Process for the production and application of micro- and nanoparticles by micronization |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8828477D0 (en) † | 1988-12-06 | 1989-01-05 | Riker Laboratories Inc | Medical aerosol formulations |
US5766573A (en) | 1988-12-06 | 1998-06-16 | Riker Laboratories, Inc. | Medicinal aerosol formulations |
US5225183A (en) * | 1988-12-06 | 1993-07-06 | Riker Laboratories, Inc. | Medicinal aerosol formulations |
US4994439A (en) * | 1989-01-19 | 1991-02-19 | California Biotechnology Inc. | Transmembrane formulations for drug administration |
US5011678A (en) * | 1989-02-01 | 1991-04-30 | California Biotechnology Inc. | Composition and method for administration of pharmaceutically active substances |
WO1994008599A1 (en) * | 1992-10-14 | 1994-04-28 | The Regents Of The University Of Colorado | Ion-pairing of drugs for improved efficacy and delivery |
WO1995003034A1 (en) * | 1993-07-19 | 1995-02-02 | Amgen Inc. | Stabilization of aerosolized proteins |
US5711934A (en) * | 1994-04-11 | 1998-01-27 | Abbott Laboratories | Process for the continuous milling of aerosol pharmaceutical formulations in aerosol propellants |
US5677184A (en) * | 1994-04-19 | 1997-10-14 | Takeda Chemical Industries, Ltd. | CHO cells that express human LH-RH receptor |
US5635159A (en) * | 1994-08-26 | 1997-06-03 | Abbott Laboratories | Aerosol drug formulations containing polyglycolyzed glycerides |
US5635161A (en) * | 1995-06-07 | 1997-06-03 | Abbott Laboratories | Aerosol drug formulations containing vegetable oils |
US7572252B1 (en) * | 1995-06-07 | 2009-08-11 | Alza Corporation | Electrotransport agent delivery method and apparatus |
US6652837B1 (en) | 1996-05-24 | 2003-11-25 | Massachusetts Institute Of Technology | Preparation of novel particles for inhalation |
US5874064A (en) | 1996-05-24 | 1999-02-23 | Massachusetts Institute Of Technology | Aerodynamically light particles for pulmonary drug delivery |
US5932547A (en) * | 1996-07-03 | 1999-08-03 | Alza Corporation | Non-aqueous polar aprotic peptide formulations |
SK284490B6 (en) * | 1996-07-03 | 2005-05-05 | Alza Corporation | Stable non-aqueous formulation and method for its preparation |
US5981489A (en) * | 1996-07-18 | 1999-11-09 | Alza Corporation | Non-aqueous protic peptide formulations |
PT954282E (en) * | 1997-01-16 | 2005-06-30 | Massachusetts Inst Technology | PREPARATION OF PARTICLES FOR INHALATION |
EP1498115A1 (en) * | 1997-01-16 | 2005-01-19 | Massachusetts Institute Of Technology | Preparation of particles for inhalation |
US6099851A (en) * | 1998-06-02 | 2000-08-08 | Weisman; Kenneth M. | Therapeutic uses of leuprolide acetate |
US7678364B2 (en) | 1999-08-25 | 2010-03-16 | Alkermes, Inc. | Particles for inhalation having sustained release properties |
US6749835B1 (en) | 1999-08-25 | 2004-06-15 | Advanced Inhalation Research, Inc. | Formulation for spray-drying large porous particles |
DE10043509A1 (en) * | 2000-09-01 | 2002-03-14 | Asta Medica Ag | Solid peptide preparations for inhalation and their manufacture |
EP1345629A2 (en) | 2000-12-29 | 2003-09-24 | Advanced Inhalation Research, Inc. | Particles for inhalation having sustained release properties |
US20030035774A1 (en) * | 2001-07-18 | 2003-02-20 | Adjei Akwete L. | Salt/ion pair medicinal aerosol formulation |
WO2005011658A2 (en) | 2003-02-27 | 2005-02-10 | Wisconsin Alumni Research Foundation | Chroman-derivated anti-androgens for treatment of androgen-mediated disorders |
US7279181B2 (en) * | 2003-06-03 | 2007-10-09 | Ferro Corporation | Method for preparation of particles from solution-in-supercritical fluid or compressed gas emulsions |
WO2005077339A1 (en) * | 2004-02-10 | 2005-08-25 | E.I. Dupont De Nemours And Company | Process for preparing stable sol of pharmaceutical ingredients and hydrofluorocarbon comprising milling the said sol, then transfert it into a canister |
HUE026152T2 (en) * | 2004-04-23 | 2016-05-30 | Philip Morris Products Sa | Aerosol generators and methods for producing aerosols |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1063512A (en) * | 1962-11-30 | 1967-03-30 | Benger Lab Ltd | Aerosols |
US3898329A (en) * | 1971-09-17 | 1975-08-05 | Sami I Said | Vasoactive intestinal peptide, composition and method |
DE2254061A1 (en) * | 1972-11-04 | 1974-05-16 | Hoechst Ag | LH-RELEASING HORMONE FOR NASAL APPLICATION |
GB1454105A (en) * | 1972-11-04 | 1976-10-27 | Hoechst Ag | Preparation containing luteinizing hormone-releasing factor |
FR2320107A1 (en) * | 1975-08-05 | 1977-03-04 | Anvar | NEW IMMUNOLOGICAL ADJUVANTS, PROCESS FOR OBTAINING THEM AND COMPOSITIONS CONTAINING THEM |
US4405598A (en) * | 1976-01-30 | 1983-09-20 | Fisons, Limited | Composition for treating asthma |
DE2750090A1 (en) * | 1976-11-19 | 1978-06-01 | Sandoz Ag | NEW FORMS OF ADMINISTRATION FOR ORGANIC COMPOUNDS |
US4438029A (en) * | 1978-01-19 | 1984-03-20 | Research Corporation | Synthetic peptides |
JPS5819669B2 (en) * | 1978-10-28 | 1983-04-19 | 白井松新薬株式会社 | Novel bioactive peptide compounds and their production methods |
JPS57188526A (en) * | 1981-05-14 | 1982-11-19 | Takeda Chem Ind Ltd | Peptide-containing pharmaceutical preparation |
US4476116A (en) * | 1982-12-10 | 1984-10-09 | Syntex (U.S.A.) Inc. | Polypeptides/chelating agent nasal compositions having enhanced peptide absorption |
JPH0625068B2 (en) * | 1982-12-10 | 1994-04-06 | シンテツクス(ユ−・エス・エ−・)インコ−ポレイテイド | Composition for intranasal administration and method for producing the same |
US4481191A (en) * | 1983-03-30 | 1984-11-06 | The Regents Of The University Of California | Method for controlling blood pressure |
GB8322178D0 (en) * | 1983-08-17 | 1983-09-21 | Sterwin Ag | Preparing aerosol compositions |
-
1987
- 1987-11-04 US US07/114,359 patent/US4897256A/en not_active Expired - Lifetime
- 1987-11-19 CA CA000552274A patent/CA1300009C/en not_active Expired - Fee Related
- 1987-11-23 ES ES92111535T patent/ES2089301T3/en not_active Expired - Lifetime
- 1987-11-23 ES ES198787117226T patent/ES2040727T3/en not_active Expired - Lifetime
- 1987-11-23 DE DE3751811T patent/DE3751811T2/en not_active Expired - Fee Related
- 1987-11-23 EP EP92111535A patent/EP0510731B1/en not_active Expired - Lifetime
- 1987-11-23 DE DE87117226T patent/DE3785570T2/en not_active Expired - Fee Related
- 1987-11-23 EP EP87117226A patent/EP0275404B1/en not_active Expired - Lifetime
- 1987-11-23 AT AT92111535T patent/ATE137963T1/en not_active IP Right Cessation
- 1987-11-25 JP JP62298857A patent/JP2533586B2/en not_active Expired - Fee Related
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10214031A1 (en) * | 2002-03-27 | 2004-02-19 | Pharmatech Gmbh | Process for the production and application of micro- and nanoparticles by micronization |
Also Published As
Publication number | Publication date |
---|---|
DE3785570T2 (en) | 1993-11-18 |
JP2533586B2 (en) | 1996-09-11 |
EP0275404A1 (en) | 1988-07-27 |
JPS63211237A (en) | 1988-09-02 |
ES2040727T3 (en) | 1993-11-01 |
EP0510731B1 (en) | 1996-05-15 |
CA1300009C (en) | 1992-05-05 |
DE3751811D1 (en) | 1996-06-20 |
EP0275404B1 (en) | 1993-04-21 |
ATE137963T1 (en) | 1996-06-15 |
ES2089301T3 (en) | 1996-10-01 |
US4897256A (en) | 1990-01-30 |
EP0510731A1 (en) | 1992-10-28 |
DE3785570D1 (en) | 1993-05-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |