DE3750668D1 - 7-[3-(Aminomethyl)-3-alkyl-1-pyrrolidinyl]chinolin-3-carbonsäure-Derivate und diese enthaltende pharmazeutische Zusammensetzungen. - Google Patents

7-[3-(Aminomethyl)-3-alkyl-1-pyrrolidinyl]chinolin-3-carbonsäure-Derivate und diese enthaltende pharmazeutische Zusammensetzungen.

Info

Publication number
DE3750668D1
DE3750668D1 DE3750668T DE3750668T DE3750668D1 DE 3750668 D1 DE3750668 D1 DE 3750668D1 DE 3750668 T DE3750668 T DE 3750668T DE 3750668 T DE3750668 T DE 3750668T DE 3750668 D1 DE3750668 D1 DE 3750668D1
Authority
DE
Germany
Prior art keywords
aminomethyl
pyrrolidinyl
alkyl
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3750668T
Other languages
English (en)
Inventor
John Michael Domagala
Susan Elizabeth Hagen
Joseph Peter Sanchez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Application granted granted Critical
Publication of DE3750668D1 publication Critical patent/DE3750668D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE3750668T 1986-07-28 1987-07-27 7-[3-(Aminomethyl)-3-alkyl-1-pyrrolidinyl]chinolin-3-carbonsäure-Derivate und diese enthaltende pharmazeutische Zusammensetzungen. Expired - Lifetime DE3750668D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88999486A 1986-07-28 1986-07-28
US07/039,438 US4771055A (en) 1986-07-28 1987-04-21 7-[[3-(aminomethyl)-3-alkyl]-1-pyrrolidinyl]-quinoline-carboxylic acids

Publications (1)

Publication Number Publication Date
DE3750668D1 true DE3750668D1 (de) 1994-11-24

Family

ID=26716130

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3750668T Expired - Lifetime DE3750668D1 (de) 1986-07-28 1987-07-27 7-[3-(Aminomethyl)-3-alkyl-1-pyrrolidinyl]chinolin-3-carbonsäure-Derivate und diese enthaltende pharmazeutische Zusammensetzungen.

Country Status (14)

Country Link
US (1) US4771055A (de)
EP (1) EP0255908B1 (de)
JP (2) JPH082896B2 (de)
KR (1) KR950008050B1 (de)
AT (1) ATE113043T1 (de)
AU (1) AU595631B2 (de)
CA (1) CA1324141C (de)
DE (1) DE3750668D1 (de)
DK (1) DK170799B1 (de)
FI (1) FI873248A (de)
NO (1) NO873125L (de)
NZ (1) NZ221021A (de)
PH (1) PH24681A (de)
PT (1) PT85411B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4822801A (en) * 1984-07-20 1989-04-18 Warner-Lambert Company 4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivative as antibacterial agents
EP0242789A3 (de) * 1986-04-25 1990-09-05 Dainippon Pharmaceutical Co., Ltd. Chinolinderivate und Verfahren zu ihrer Herstellung
US5591744A (en) * 1987-04-16 1997-01-07 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
US5173484A (en) * 1988-02-05 1992-12-22 Bayer Aktiengesellschaft Quinolone- and naphthyridone carboxylic acid derivatives, process for their production, antibacterial compositions and feed additives containing them
DE3814517A1 (de) * 1988-02-05 1989-08-17 Bayer Ag Chinolon- und naphthyridoncarbonsaeurederivate, verfahren zu ihrer herstellung und sie enthaltende antibakterielle mittel und futterzusatzstoffe
DE68920773T2 (de) * 1988-05-19 1995-05-18 Chugai Pharmaceutical Co Ltd Chinoloncarbonsäure-Derivate.
US5039682A (en) * 1988-06-21 1991-08-13 Pfizer Inc. 6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acid derivatives and intermediates therefor
US5103040A (en) * 1988-06-21 1992-04-07 Pfizer Inc. 6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acid derivatives and intermediates therefor
US5233091A (en) * 1988-06-21 1993-08-03 Pfizer Inc. 6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acid derivatives and intermediates therefor
JPH0674261B2 (ja) * 1988-06-21 1994-09-21 塩野義製薬株式会社 キノロンカルボン酸誘導体
US5104868A (en) * 1988-06-21 1992-04-14 Pfizer Inc. Tricyclic derivatives of 7-substituted-6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acids and esters
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
CA1332605C (en) * 1988-10-03 1994-10-18 Yasuhiro Nishitani Pyridonecarboxylic acids
ES2147721T3 (es) 1990-04-18 2000-10-01 Procter & Gamble Pharma Quinolonil lactamas antimicrobianas.
DE4104870A1 (de) * 1991-02-17 1992-08-27 Bayer Ag Verwendung von 3,(4)-substituierten pyrrolidinen als katalysatoren fuer das polyisocyanatpolyadditionsverfahren, verfahren zu ihrer herstellung sowie verfahren zur herstellung von polyurethan(harnstoff)en
TW252107B (de) * 1993-08-27 1995-07-21 Hokuriku Pharmacetical Co Ltd
EP0806421A4 (de) * 1995-01-24 1998-04-15 Hokuriku Pharmaceutical Derivate der chinolincarbonsäure
US6211375B1 (en) 1996-04-19 2001-04-03 Wakunaga Pharmaceutical Co., Ltd. Pyridonecarboxylic acid derivatives or salts thereof and antibacterial agents containing the same as the active ingredient
ID16655A (id) * 1996-04-24 1997-10-30 Daiichi Seiyaku Co Turunan-turunan sikloalkilaminometilpirolidina
AU2004272414B2 (en) 2003-09-10 2009-05-28 Kyorin Pharmaceutical Co., Ltd. 7-(4-substituted 3- cyclopropylaminomethyl-1- pyrrolidinyl) quinolonecarboxylic acid derivative
WO2008143343A1 (ja) * 2007-05-24 2008-11-27 Kyorin Pharmaceutical Co., Ltd. １４位置換基に複素芳香環カルボン酸構造を有するムチリン誘導体

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4665079A (en) * 1984-02-17 1987-05-12 Warner-Lambert Company Antibacterial agents
IE55898B1 (en) * 1982-09-09 1991-02-14 Warner Lambert Co Antibacterial agents
NZ208470A (en) * 1983-07-18 1988-06-30 Abbott Lab 6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid derivatives and antibacterial compositions containing such
CS274601B2 (en) * 1983-07-27 1991-09-15 Dainippon Pharmaceutical Co Method of 1,8-naphthyridine derivative production
EP0154780B1 (de) * 1984-01-26 1990-04-11 Abbott Laboratories Antibakterielle Chinolinderivate
DE3420743A1 (de) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-6,8-dihalogen-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
IE58742B1 (en) * 1984-07-20 1993-11-05 Warner Lambert Co Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds
JPH0670032B2 (ja) * 1984-11-22 1994-09-07 大日本製薬株式会社 アミノピロリジン誘導体、そのエステルおよびその塩

Also Published As

Publication number Publication date
JP2628541B2 (ja) 1997-07-09
EP0255908A3 (en) 1989-10-25
PT85411B (pt) 1990-06-29
NZ221021A (en) 1991-06-25
DK390587D0 (da) 1987-07-27
DK390587A (da) 1988-01-29
EP0255908B1 (de) 1994-10-19
JPH082896B2 (ja) 1996-01-17
FI873248A0 (fi) 1987-07-24
JPH08169876A (ja) 1996-07-02
DK170799B1 (da) 1996-01-22
US4771055A (en) 1988-09-13
AU7608387A (en) 1988-02-04
FI873248A (fi) 1988-01-29
PH24681A (en) 1990-09-07
JPS6379885A (ja) 1988-04-09
AU595631B2 (en) 1990-04-05
NO873125L (no) 1988-01-29
KR950008050B1 (ko) 1995-07-24
CA1324141C (en) 1993-11-09
ATE113043T1 (de) 1994-11-15
NO873125D0 (no) 1987-07-27
EP0255908A2 (de) 1988-02-17
KR880001633A (ko) 1988-04-25
PT85411A (en) 1987-08-01

Similar Documents

Publication Publication Date Title
DE3750668D1 (de) 7-[3-(Aminomethyl)-3-alkyl-1-pyrrolidinyl]chinolin-3-carbonsäure-Derivate und diese enthaltende pharmazeutische Zusammensetzungen.
DK543787A (da) Naphthyridin-, quinolin- og benzoxazincarboxylsyreforbindelser med antibakteriel aktivitet
NO176356C (no) Analogifremgangsmåte for fremstilling av nye terapeutisk aktive pyrazolopyridinforbindelser
NZ227680A (en) Quinoline and naphthyridine derivatives, intermediates and pharmaceutical compositions
FI872864A0 (fi) Menetelmä farmaseuttisesti aktiivisten bentsimidatsolijohdannaisten valmistamiseksi
NO180719C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive A-nor-steroid-3-carboxylsyrederivater
TR199801642T2 (xx) Tedavide faydal� olan karbamik asitlerin azabisiklik esterleri.
PH23256A (en) A process for the preparation of quinolone carboxylic acid derivatives
DK0612731T3 (da) Nye quinolon- og naphthyridoncarboxylsyrederivater
NO163331C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive 6,7-disubstituerte 1-cyklopropyl-1,4-dihydro-4-okso-1,8-naftyridin-3-karboksylsyrer.
DK454685A (da) Pyrazolo(3,4-b)-pyridinamider
NO900342L (no) Fremgangsmaate for fremstilling av terapeutisk aktive 3-fenyl-5,6-dihydrobenz(c)akridin-7-karboxylsyrer og beslektede forbindelser.
NO901171D0 (no) Fremgangsmaate til fremstilling av substituerte azetidinylpyridonkarboksylsyrederivater.
FI893677A0 (fi) Menetelmä terapeuttisesti käyttökelpoisten 6-fluori-3,5-dihydroksikarboksyylihappojen ja niiden johdannaisten valmistamiseksi
SE8601799D0 (sv) (-)-1beta-ethyl-1alfa-hydroxymethyl-1,2,3,4,6,7,12,12balfa-octahydroindolo/2,3-a/quinolizine, process for its preparation and pharmaceutical compositions containing same
DE68903019D1 (de) 4,5,6,7-tetrahydroisothiazolo (4,5-c)pyridin-derivate und isomere.
IT1229846B (it) Esteri di catecolammine.
IT1224404B (it) Composti attivi sul sistema cardiovascolare

Legal Events

Date Code Title Description
8332 No legal effect for de