DE3750350D1 - Verfahren zur Herstellung von phosphonischen Säuren. - Google Patents

Verfahren zur Herstellung von phosphonischen Säuren.

Info

Publication number: DE3750350D1
Authority: DE; Germany
Prior art keywords: arylalkyl; lower alkyl; preparing; acid; preparation
Prior art date: 1986-05-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE3750350T

Other languages

English (en)

Other versions

DE3750350T2 (de

Inventor

John Kurian Thottathil

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

ER Squibb and Sons LLC

Original Assignee

ER Squibb and Sons LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-05-12

Filing date

1987-05-01

Publication date

1994-09-15

1987-05-01 Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC

1994-09-15 Application granted granted Critical

1994-09-15 Publication of DE3750350D1 publication Critical patent/DE3750350D1/de

1994-12-22 Publication of DE3750350T2 publication Critical patent/DE3750350T2/de

2007-05-02 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

238000000034 method Methods 0.000 title abstract 3
150000003009 phosphonic acids Chemical class 0.000 title 1
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 3
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
OZAIFHULBGXAKX-UHFFFAOYSA-N 2-(2-cyanopropan-2-yldiazenyl)-2-methylpropanenitrile Chemical compound N#CC(C)(C)N=NC(C)(C)C#N OZAIFHULBGXAKX-UHFFFAOYSA-N 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
125000003710 aryl alkyl group Chemical group 0.000 abstract 2
ACVYVLVWPXVTIT-UHFFFAOYSA-N phosphinic acid Chemical compound O[PH2]=O ACVYVLVWPXVTIT-UHFFFAOYSA-N 0.000 abstract 2
XRBCRPZXSCBRTK-UHFFFAOYSA-N phosphonous acid Chemical class OPO XRBCRPZXSCBRTK-UHFFFAOYSA-N 0.000 abstract 2
KWSLGOVYXMQPPX-UHFFFAOYSA-N 5-[3-(trifluoromethyl)phenyl]-2h-tetrazole Chemical compound FC(F)(F)C1=CC=CC(C2=NNN=N2)=C1 KWSLGOVYXMQPPX-UHFFFAOYSA-N 0.000 abstract 1
239000005541 ACE inhibitor Substances 0.000 abstract 1
ABLZXFCXXLZCGV-UHFFFAOYSA-N Phosphorous acid Chemical compound OP(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 abstract 1
OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract 1
230000002378 acidificating effect Effects 0.000 abstract 1
150000001336 alkenes Chemical class 0.000 abstract 1
125000005907 alkyl ester group Chemical group 0.000 abstract 1
229940044094 angiotensin-converting-enzyme inhibitor Drugs 0.000 abstract 1
239000003153 chemical reaction reagent Substances 0.000 abstract 1
239000003999 initiator Substances 0.000 abstract 1
JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 abstract 1
239000003960 organic solvent Substances 0.000 abstract 1
239000011574 phosphorus Substances 0.000 abstract 1
229910052698 phosphorus Inorganic materials 0.000 abstract 1
238000010992 reflux Methods 0.000 abstract 1
229910001379 sodium hypophosphite Inorganic materials 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1
125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/48—Phosphonous acids [RP(OH)2] including [RHP(=O)(OH)]; Thiophosphonous acids including [RP(SH)2], [RHP(=S)(SH)]; Derivatives thereof

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DE3750350T 1986-05-12 1987-05-01 Verfahren zur Herstellung von phosphonischen Säuren. Expired - Fee Related DE3750350T2 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US86179486A	1986-05-12	1986-05-12

Publications (2)

Publication Number	Publication Date
DE3750350D1 true DE3750350D1 (de)	1994-09-15
DE3750350T2 DE3750350T2 (de)	1994-12-22

Family

ID=25336780

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE3750350T Expired - Fee Related DE3750350T2 (de)	1986-05-12	1987-05-01	Verfahren zur Herstellung von phosphonischen Säuren.

Country Status (6)

Country	Link
EP (1)	EP0246015B1 (de)
JP (1)	JP2525408B2 (de)
AT (1)	ATE109786T1 (de)
CA (1)	CA1298855C (de)
DE (1)	DE3750350T2 (de)
IE (1)	IE64616B1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5647995A (en) *	1994-04-29	1997-07-15	Nalco Chemical Company	Method for the control of calcium carbonate scale using compounds prepared from acetylenic compounds and inorganic phosphite salts and their derivatives
EP1218387B1 (de) *	1999-09-16	2003-05-07	Lupin Limited	Verbesserte regioselektive synthese von phosphonigsäuren

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL145897B (nl) *	1948-04-12		Union Carbide Corp	Werkwijze voor het bereiden van korrelvormige wasmiddelen.
SU525700A1 (ru) *	1974-07-04	1976-08-25	Московский Ордена Ленина И Ордена Трудового Красного Знамени Государственный Педагогический Институт Им.В.И.Ленина	Способ одновременного получени алкилфосфонистых и диалкилфосфиновых кислот
US4590014A (en) *	1984-09-06	1986-05-20	Economics Laboratory, Inc.	Synthesis of alkyl phosphinate salts

1987
- 1987-04-28 CA CA000535803A patent/CA1298855C/en not_active Expired - Lifetime
- 1987-05-01 EP EP87303962A patent/EP0246015B1/de not_active Expired - Lifetime
- 1987-05-01 DE DE3750350T patent/DE3750350T2/de not_active Expired - Fee Related
- 1987-05-01 AT AT87303962T patent/ATE109786T1/de not_active IP Right Cessation
- 1987-05-11 IE IE121887A patent/IE64616B1/en not_active IP Right Cessation
- 1987-05-11 JP JP62114398A patent/JP2525408B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE3750350T2 (de)	1994-12-22
IE64616B1 (en)	1995-08-23
ATE109786T1 (de)	1994-08-15
JP2525408B2 (ja)	1996-08-21
EP0246015A3 (en)	1989-08-16
EP0246015A2 (de)	1987-11-19
IE871218L (en)	1987-11-12
JPS638392A (ja)	1988-01-14
CA1298855C (en)	1992-04-14
EP0246015B1 (de)	1994-08-10

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Legal Events

Date	Code	Title	Description
1995-09-07	8364	No opposition during term of opposition
2006-03-16	8339	Ceased/non-payment of the annual fee