DE3688311D1 - Verfahren zum zuechten von rekombinanten zellen. - Google Patents

Verfahren zum zuechten von rekombinanten zellen.

Info

Publication number
DE3688311D1
DE3688311D1 DE8686114159T DE3688311T DE3688311D1 DE 3688311 D1 DE3688311 D1 DE 3688311D1 DE 8686114159 T DE8686114159 T DE 8686114159T DE 3688311 T DE3688311 T DE 3688311T DE 3688311 D1 DE3688311 D1 DE 3688311D1
Authority
DE
Germany
Prior art keywords
recombinant cells
growing recombinant
growing
cells
recombinant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686114159T
Other languages
English (en)
Other versions
DE3688311T2 (de
Inventor
Norio Shimizu
Shinichi Fukuzono
Nobuko Nishimura
Kiyoshi Fujimori
Yoji Odawara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hitachi Ltd
Original Assignee
Hitachi Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hitachi Ltd filed Critical Hitachi Ltd
Publication of DE3688311D1 publication Critical patent/DE3688311D1/de
Application granted granted Critical
Publication of DE3688311T2 publication Critical patent/DE3688311T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/10Protozoa; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2468Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on beta-galactose-glycoside bonds, e.g. carrageenases (3.2.1.83; 3.2.1.157); beta-agarase (3.2.1.81)
    • C12N9/2471Beta-galactosidase (3.2.1.23), i.e. exo-(1-->4)-beta-D-galactanase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01023Beta-galactosidase (3.2.1.23), i.e. exo-(1-->4)-beta-D-galactanase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DE86114159T 1985-10-14 1986-10-13 Verfahren zum Züchten von rekombinanten Zellen. Expired - Fee Related DE3688311T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP60226785A JPH07110232B2 (ja) 1985-10-14 1985-10-14 遺伝子組換え大腸菌の遺伝子生産物を採取する方法および装置

Publications (2)

Publication Number Publication Date
DE3688311D1 true DE3688311D1 (de) 1993-05-27
DE3688311T2 DE3688311T2 (de) 1993-10-28

Family

ID=16850574

Family Applications (1)

Application Number Title Priority Date Filing Date
DE86114159T Expired - Fee Related DE3688311T2 (de) 1985-10-14 1986-10-13 Verfahren zum Züchten von rekombinanten Zellen.

Country Status (5)

Country Link
US (1) US5445948A (de)
EP (1) EP0219791B1 (de)
JP (1) JPH07110232B2 (de)
KR (1) KR890004020B1 (de)
DE (1) DE3688311T2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE84568T1 (de) * 1985-08-15 1993-01-15 Amgen Inc Gaerverfahren zur herstellung von hepatitisimpfstoff.
IL82746A (en) * 1986-06-06 1994-10-07 Genentech Inc A process for producing a biologically active tissue plasminogen activator
JP2676511B2 (ja) * 1987-03-23 1997-11-17 株式会社日立製作所 酢酸を指標とした培養方法及びその装置
CA1322735C (en) * 1987-11-07 1993-10-05 Shinichiro Haze Microorganism having low acetate forming capability, and process for production of useful substrate using same
JPH0227993A (ja) * 1988-07-15 1990-01-30 Nippon Shinyaku Co Ltd hEGFの製法
US5955323A (en) * 1996-08-01 1999-09-21 American Home Products Corporation Automated high-yield fermentation of plasmid DNA in Escherichia coli
US20030017554A1 (en) * 2000-11-15 2003-01-23 Mechthild Rieping Process for the fermentative preparation of L-amino acids using strains of the enterobacteriaceae family
US20030054503A1 (en) * 2001-04-03 2003-03-20 Degussa Ag Process for the production of L-amino acids using strains of the family enterobacteriaceae that contain an attenuated dgsA gene
EP1407022B1 (de) * 2001-07-18 2009-09-02 Evonik Degussa GmbH Verfahren zur herstellung von l-aminosäuren durch enterobakteriaceae-stämmen mit verstärkter exprimierung des rsea-gens
JPWO2003016907A1 (ja) * 2001-08-17 2004-12-02 エーザイ株式会社 生体試料中のラミニン5抗原の測定試薬及び測定方法
EP1498475A1 (de) * 2003-07-18 2005-01-19 Meristem Therapeutics S.A. Bioreaktor und Verfahren zur kontinuierlichen Züchtung von Pflanzenzellen
GB0704025D0 (en) * 2007-03-02 2007-04-11 Ekb Technology Ltd Inhibitory product removal

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS49126882A (de) * 1973-04-19 1974-12-04
US4282255A (en) * 1979-06-28 1981-08-04 State Of Oregon, By And Through The Oregon State Board Of Higher Education On Behalf Of Oregon State University Method and starter compositions for the growth of acid producing bacteria and bacterial compositions produced thereby
US4420398A (en) * 1981-08-13 1983-12-13 American National Red Cross Filteration method for cell produced antiviral substances
JPS58141796A (ja) * 1982-02-18 1983-08-23 Kyowa Hakko Kogyo Co Ltd ペプチドの製造法
ZA839242B (en) * 1982-12-15 1984-09-26 Bio Response Inc A method and system for culturing and treating substances disposed in a flowing culture fluid
BG49718A3 (en) * 1983-07-15 1992-01-15 Bio Technology General Corp Method for preparing of polypeptid with superoxiddismutasne activitty
EP0165613B1 (de) * 1984-06-22 1992-01-15 Hitachi, Ltd. Verfahren zum Kontrollieren der Züchtung von Rekombinanten
JPH078231B2 (ja) * 1985-03-25 1995-02-01 株式会社日立製作所 培養制御方法及び培養制御装置

Also Published As

Publication number Publication date
EP0219791B1 (de) 1993-04-21
EP0219791A2 (de) 1987-04-29
JPS6287086A (ja) 1987-04-21
EP0219791A3 (en) 1988-09-07
KR890004020B1 (ko) 1989-10-16
JPH07110232B2 (ja) 1995-11-29
US5445948A (en) 1995-08-29
KR870004130A (ko) 1987-05-07
DE3688311T2 (de) 1993-10-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee