DE3683483D1 - Neue benzothiazinabkoemmlinge. - Google Patents

Neue benzothiazinabkoemmlinge.

Info

Publication number
DE3683483D1
DE3683483D1 DE8686904393T DE3683483T DE3683483D1 DE 3683483 D1 DE3683483 D1 DE 3683483D1 DE 8686904393 T DE8686904393 T DE 8686904393T DE 3683483 T DE3683483 T DE 3683483T DE 3683483 D1 DE3683483 D1 DE 3683483D1
Authority
DE
Germany
Prior art keywords
hydrogen
pct
lower alkyl
nitro
sec
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686904393T
Other languages
English (en)
Inventor
Jun-Ichi Iwao
Tadashi Iso
Masayuki Oya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Santen Pharmaceutical Co Ltd
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/JP1985/000426 external-priority patent/WO1987000837A1/ja
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE3683483D1 publication Critical patent/DE3683483D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/16—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Sheets, Magazines, And Separation Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE8686904393T 1985-07-29 1986-07-21 Neue benzothiazinabkoemmlinge. Expired - Lifetime DE3683483D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/JP1985/000426 WO1987000837A1 (en) 1985-07-29 1985-07-29 Novel benzothiazine derivatives
JP17353185 1985-08-06
PCT/JP1986/000379 WO1987000838A1 (en) 1985-07-29 1986-07-21 Novel benzothiazine derivatives

Publications (1)

Publication Number Publication Date
DE3683483D1 true DE3683483D1 (de) 1992-02-27

Family

ID=15962257

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686904393T Expired - Lifetime DE3683483D1 (de) 1985-07-29 1986-07-21 Neue benzothiazinabkoemmlinge.

Country Status (10)

Country Link
US (1) US4786635A (de)
EP (1) EP0237573B1 (de)
KR (1) KR890004196B1 (de)
AT (1) ATE71622T1 (de)
AU (1) AU587057B2 (de)
DE (1) DE3683483D1 (de)
DK (1) DK158087A (de)
FI (1) FI87352C (de)
NO (1) NO170082C (de)
WO (1) WO1987000838A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3614363A1 (de) * 1986-04-28 1987-10-29 Hoechst Ag Benzothiazinon-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
AT389112B (de) * 1987-10-08 1989-10-25 Hoechst Ag Benzothiazinon-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
AT389113B (de) * 1987-10-08 1989-10-25 Hoechst Ag Neue benzothiazinon-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
US5182276A (en) * 1989-06-16 1993-01-26 Santen Pharmaceutical Co., Ltd. Nootropic agent
DK0492164T3 (da) * 1990-11-29 1996-06-24 Santen Pharmaceutical Co Ltd Terapeutisk middel til glaucoma indeholdende 2-phenyl-3-oxo-2H-1,4-benzothiazinderivater
IL137656A0 (en) * 1998-03-31 2001-10-31 Warner Lambert Co Benzoxazinones/benzothiazinones as serine protease inhibitors
MXPA05001958A (es) 2002-08-19 2005-04-28 Pfizer Prod Inc Terapia de combinacion para enfermedades hiperproliferativas.
CN101090714A (zh) * 2004-07-26 2007-12-19 康泽里克斯公司 通过吸入伊洛前列素和微粒制剂治疗肺动脉高血压症
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
EP2351569B1 (de) 2005-10-26 2012-08-22 Asahi Kasei Pharma Corporation Kombinationstherapie mit Fasudil zur Behandlung von pulmonaler Hypertonie
ATE551059T1 (de) 2005-10-26 2012-04-15 Asahi Kasei Pharma Corp Fasudil in kombination mit bosentan zur behandlung von pulmonaler arterieller hypertonie
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US7919506B2 (en) 2006-03-10 2011-04-05 Pfizer Inc. Dibenzyl amine compounds and derivatives
CN101663262B (zh) 2006-12-01 2014-03-26 百时美施贵宝公司 用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物
US20090069413A1 (en) * 2007-09-09 2009-03-12 Protia, Llc Deuterium-enriched olopatadine
WO2012037665A1 (en) 2010-09-24 2012-03-29 Oral Delivery Technology Ltd. Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions
CN105143203A (zh) 2013-04-17 2015-12-09 辉瑞大药厂 用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
CN113574055B (zh) 2019-01-18 2024-07-23 阿斯利康(瑞典)有限公司 Pcsk9抑制剂及其使用方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5651465A (en) * 1979-10-02 1981-05-09 Yoshitomi Pharmaceut Ind Ltd Benzothiazine derivative
JPS59144775A (ja) * 1983-02-07 1984-08-18 Santen Pharmaceut Co Ltd ヒドロキシフエニルベンゾチアジン誘導体およびその製造法
US4584300A (en) * 1983-02-07 1986-04-22 Santen Pharmaceutical Co., Ltd. Platelet anti-aggregative- and calcium antagonistic -1,4-benzothiazin-3-one derivatives, compositions, and methods of use therefor
JPS59148771A (ja) * 1983-02-09 1984-08-25 Santen Pharmaceut Co Ltd ベンゾチアジン誘導体
DE3347173A1 (de) * 1983-12-27 1985-07-04 Hoechst Ag, 6230 Frankfurt Neue benzothiazin-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
JPS60166674A (ja) * 1984-02-09 1985-08-29 Santen Pharmaceut Co Ltd ベンゾチアジン誘導体
JPH0625186B2 (ja) * 1985-03-19 1994-04-06 参天製薬株式会社 ２−アリ−ルベンゾチアジン誘導体
AU4673285A (en) * 1985-07-29 1987-03-05 Santen Pharmaceutical Co. Ltd. Novel benzothiazine derivatives

Also Published As

Publication number Publication date
FI87352C (fi) 1992-12-28
EP0237573B1 (de) 1992-01-15
AU587057B2 (en) 1989-08-03
NO871314D0 (no) 1987-03-27
FI871322A0 (fi) 1987-03-26
NO170082C (no) 1992-09-09
EP0237573A4 (de) 1987-10-26
DK158087D0 (da) 1987-03-27
ATE71622T1 (de) 1992-02-15
AU6137186A (en) 1987-03-05
FI871322A (fi) 1987-03-26
EP0237573A1 (de) 1987-09-23
US4786635A (en) 1988-11-22
FI87352B (fi) 1992-09-15
DK158087A (da) 1987-03-27
NO170082B (no) 1992-06-01
KR870700613A (ko) 1987-12-30
KR890004196B1 (ko) 1989-10-27
WO1987000838A1 (en) 1987-02-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee