DE3683483D1 - Neue benzothiazinabkoemmlinge. - Google Patents
Neue benzothiazinabkoemmlinge.Info
- Publication number
- DE3683483D1 DE3683483D1 DE8686904393T DE3683483T DE3683483D1 DE 3683483 D1 DE3683483 D1 DE 3683483D1 DE 8686904393 T DE8686904393 T DE 8686904393T DE 3683483 T DE3683483 T DE 3683483T DE 3683483 D1 DE3683483 D1 DE 3683483D1
- Authority
- DE
- Germany
- Prior art keywords
- hydrogen
- pct
- lower alkyl
- nitro
- sec
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/16—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Sheets, Magazines, And Separation Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/JP1985/000426 WO1987000837A1 (en) | 1985-07-29 | 1985-07-29 | Novel benzothiazine derivatives |
JP17353185 | 1985-08-06 | ||
PCT/JP1986/000379 WO1987000838A1 (en) | 1985-07-29 | 1986-07-21 | Novel benzothiazine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3683483D1 true DE3683483D1 (de) | 1992-02-27 |
Family
ID=15962257
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8686904393T Expired - Lifetime DE3683483D1 (de) | 1985-07-29 | 1986-07-21 | Neue benzothiazinabkoemmlinge. |
Country Status (10)
Country | Link |
---|---|
US (1) | US4786635A (de) |
EP (1) | EP0237573B1 (de) |
KR (1) | KR890004196B1 (de) |
AT (1) | ATE71622T1 (de) |
AU (1) | AU587057B2 (de) |
DE (1) | DE3683483D1 (de) |
DK (1) | DK158087A (de) |
FI (1) | FI87352C (de) |
NO (1) | NO170082C (de) |
WO (1) | WO1987000838A1 (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3614363A1 (de) * | 1986-04-28 | 1987-10-29 | Hoechst Ag | Benzothiazinon-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung |
AT389112B (de) * | 1987-10-08 | 1989-10-25 | Hoechst Ag | Benzothiazinon-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung |
AT389113B (de) * | 1987-10-08 | 1989-10-25 | Hoechst Ag | Neue benzothiazinon-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung |
US5182276A (en) * | 1989-06-16 | 1993-01-26 | Santen Pharmaceutical Co., Ltd. | Nootropic agent |
DK0492164T3 (da) * | 1990-11-29 | 1996-06-24 | Santen Pharmaceutical Co Ltd | Terapeutisk middel til glaucoma indeholdende 2-phenyl-3-oxo-2H-1,4-benzothiazinderivater |
IL137656A0 (en) * | 1998-03-31 | 2001-10-31 | Warner Lambert Co | Benzoxazinones/benzothiazinones as serine protease inhibitors |
MXPA05001958A (es) | 2002-08-19 | 2005-04-28 | Pfizer Prod Inc | Terapia de combinacion para enfermedades hiperproliferativas. |
CN101090714A (zh) * | 2004-07-26 | 2007-12-19 | 康泽里克斯公司 | 通过吸入伊洛前列素和微粒制剂治疗肺动脉高血压症 |
US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
EP2351569B1 (de) | 2005-10-26 | 2012-08-22 | Asahi Kasei Pharma Corporation | Kombinationstherapie mit Fasudil zur Behandlung von pulmonaler Hypertonie |
ATE551059T1 (de) | 2005-10-26 | 2012-04-15 | Asahi Kasei Pharma Corp | Fasudil in kombination mit bosentan zur behandlung von pulmonaler arterieller hypertonie |
US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
US7919506B2 (en) | 2006-03-10 | 2011-04-05 | Pfizer Inc. | Dibenzyl amine compounds and derivatives |
CN101663262B (zh) | 2006-12-01 | 2014-03-26 | 百时美施贵宝公司 | 用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物 |
US20090069413A1 (en) * | 2007-09-09 | 2009-03-12 | Protia, Llc | Deuterium-enriched olopatadine |
WO2012037665A1 (en) | 2010-09-24 | 2012-03-29 | Oral Delivery Technology Ltd. | Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions |
CN105143203A (zh) | 2013-04-17 | 2015-12-09 | 辉瑞大药厂 | 用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物 |
WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
CN113574055B (zh) | 2019-01-18 | 2024-07-23 | 阿斯利康(瑞典)有限公司 | Pcsk9抑制剂及其使用方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5651465A (en) * | 1979-10-02 | 1981-05-09 | Yoshitomi Pharmaceut Ind Ltd | Benzothiazine derivative |
JPS59144775A (ja) * | 1983-02-07 | 1984-08-18 | Santen Pharmaceut Co Ltd | ヒドロキシフエニルベンゾチアジン誘導体およびその製造法 |
US4584300A (en) * | 1983-02-07 | 1986-04-22 | Santen Pharmaceutical Co., Ltd. | Platelet anti-aggregative- and calcium antagonistic -1,4-benzothiazin-3-one derivatives, compositions, and methods of use therefor |
JPS59148771A (ja) * | 1983-02-09 | 1984-08-25 | Santen Pharmaceut Co Ltd | ベンゾチアジン誘導体 |
DE3347173A1 (de) * | 1983-12-27 | 1985-07-04 | Hoechst Ag, 6230 Frankfurt | Neue benzothiazin-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung |
JPS60166674A (ja) * | 1984-02-09 | 1985-08-29 | Santen Pharmaceut Co Ltd | ベンゾチアジン誘導体 |
JPH0625186B2 (ja) * | 1985-03-19 | 1994-04-06 | 参天製薬株式会社 | 2−アリ−ルベンゾチアジン誘導体 |
AU4673285A (en) * | 1985-07-29 | 1987-03-05 | Santen Pharmaceutical Co. Ltd. | Novel benzothiazine derivatives |
-
1986
- 1986-07-21 KR KR1019870700275A patent/KR890004196B1/ko not_active IP Right Cessation
- 1986-07-21 AU AU61371/86A patent/AU587057B2/en not_active Ceased
- 1986-07-21 US US07/034,164 patent/US4786635A/en not_active Expired - Fee Related
- 1986-07-21 WO PCT/JP1986/000379 patent/WO1987000838A1/ja active IP Right Grant
- 1986-07-21 AT AT86904393T patent/ATE71622T1/de not_active IP Right Cessation
- 1986-07-21 EP EP86904393A patent/EP0237573B1/de not_active Expired - Lifetime
- 1986-07-21 DE DE8686904393T patent/DE3683483D1/de not_active Expired - Lifetime
-
1987
- 1987-03-26 FI FI871322A patent/FI87352C/fi not_active IP Right Cessation
- 1987-03-27 NO NO871314A patent/NO170082C/no not_active IP Right Cessation
- 1987-03-27 DK DK158087A patent/DK158087A/da unknown
Also Published As
Publication number | Publication date |
---|---|
FI87352C (fi) | 1992-12-28 |
EP0237573B1 (de) | 1992-01-15 |
AU587057B2 (en) | 1989-08-03 |
NO871314D0 (no) | 1987-03-27 |
FI871322A0 (fi) | 1987-03-26 |
NO170082C (no) | 1992-09-09 |
EP0237573A4 (de) | 1987-10-26 |
DK158087D0 (da) | 1987-03-27 |
ATE71622T1 (de) | 1992-02-15 |
AU6137186A (en) | 1987-03-05 |
FI871322A (fi) | 1987-03-26 |
EP0237573A1 (de) | 1987-09-23 |
US4786635A (en) | 1988-11-22 |
FI87352B (fi) | 1992-09-15 |
DK158087A (da) | 1987-03-27 |
NO170082B (no) | 1992-06-01 |
KR870700613A (ko) | 1987-12-30 |
KR890004196B1 (ko) | 1989-10-27 |
WO1987000838A1 (en) | 1987-02-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |