DE3678564D1 - Tryptamin-derivate, ihre herstellung und anwendung in heilmitteln. - Google Patents

Tryptamin-derivate, ihre herstellung und anwendung in heilmitteln.

Info

Publication number
DE3678564D1
DE3678564D1 DE8686309647T DE3678564T DE3678564D1 DE 3678564 D1 DE3678564 D1 DE 3678564D1 DE 8686309647 T DE8686309647 T DE 8686309647T DE 3678564 T DE3678564 T DE 3678564T DE 3678564 D1 DE3678564 D1 DE 3678564D1
Authority
DE
Germany
Prior art keywords
sub
alkyl
production
integer
zero
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686309647T
Other languages
English (en)
Inventor
William Alexander Oxford
David Edmund Bays
Ian Harold Coates
Colin Frederick Webb
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DE3678564D1 publication Critical patent/DE3678564D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16Tryptamines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE8686309647T 1985-12-11 1986-12-11 Tryptamin-derivate, ihre herstellung und anwendung in heilmitteln. Expired - Fee Related DE3678564D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858530507A GB8530507D0 (en) 1985-12-11 1985-12-11 Chemical compounds

Publications (1)

Publication Number Publication Date
DE3678564D1 true DE3678564D1 (de) 1991-05-08

Family

ID=10589593

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686309647T Expired - Fee Related DE3678564D1 (de) 1985-12-11 1986-12-11 Tryptamin-derivate, ihre herstellung und anwendung in heilmitteln.

Country Status (9)

Country Link
US (1) US4870096A (de)
EP (1) EP0237678B1 (de)
JP (1) JPS62195363A (de)
AT (1) ATE62225T1 (de)
AU (1) AU584483B2 (de)
CA (1) CA1281334C (de)
DE (1) DE3678564D1 (de)
GB (1) GB8530507D0 (de)
ZA (1) ZA869351B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8431426D0 (en) * 1984-12-13 1985-01-23 Glaxo Group Ltd Chemical compounds
US5225431A (en) * 1987-10-23 1993-07-06 Burroughs Wellcome Co. Therapeutic substituted indole compounds and compositions thereof
CA2042295A1 (fr) * 1990-05-15 1991-11-16 Jacques Chauveau Derives de mediateurs endogenes, leurs sels, procede de preparation, applications, et compositions les renfermant
GB9013845D0 (en) * 1990-06-21 1990-08-15 Glaxo Group Ltd Process
GB9211277D0 (en) 1992-05-28 1992-07-15 Glaxo Group Inc Pharmaceutical compositions
KR960701865A (ko) * 1993-04-22 1996-03-28 데이비드 존. 우드 편두통에 사용하는 5-HT1 유사 효능제인 인돌 유도체(Indole Derivatives as 5-HT, -Like Agonists for Use in Migraine)
US5504101A (en) * 1994-05-06 1996-04-02 Allelix Biopharmaceuticals, Inc. 5-HT-1D receptor ligands
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
US7351719B2 (en) 2002-10-31 2008-04-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds
US7592373B2 (en) 2003-12-23 2009-09-22 Boehringer Ingelheim International Gmbh Amide compounds with MCH antagonistic activity and medicaments comprising these compounds
DE10360745A1 (de) * 2003-12-23 2005-07-28 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Amid-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel
US7524862B2 (en) 2004-04-14 2009-04-28 Boehringer Ingelheim International Gmbh Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds
DE102004017934A1 (de) 2004-04-14 2005-11-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA795239B (en) * 1978-10-12 1980-11-26 Glaxo Group Ltd Heterocyclic compounds
GB2082175B (en) * 1980-08-12 1984-05-02 Glaxo Group Ltd Heterocyclic compounds
SE454880B (sv) * 1980-08-12 1988-06-06 Glaxo Group Ltd 3-aminoalkyl-1h-indol-5-acetamider, forfarande for framstellning av dessa och en farmaceutisk komposition for behandling av migren
ZW19381A1 (en) * 1980-08-12 1983-03-09 Glaxo Group Ltd Heterocyclic compounds
GB8332437D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Chemical compounds
GB8431426D0 (en) * 1984-12-13 1985-01-23 Glaxo Group Ltd Chemical compounds
GB8600397D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
GB8614287D0 (en) * 1986-06-12 1986-07-16 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
US4870096A (en) 1989-09-26
JPS62195363A (ja) 1987-08-28
EP0237678B1 (de) 1991-04-03
ZA869351B (en) 1988-07-27
AU6644586A (en) 1987-06-18
GB8530507D0 (en) 1986-01-22
CA1281334C (en) 1991-03-12
EP0237678A1 (de) 1987-09-23
ATE62225T1 (de) 1991-04-15
AU584483B2 (en) 1989-05-25

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee