DE3677851D1 - Verfahren zur steigerung der produktion von rekombinantem protein in hefearten der gattung saccharomyces. - Google Patents

Verfahren zur steigerung der produktion von rekombinantem protein in hefearten der gattung saccharomyces.

Info

Publication number
DE3677851D1
DE3677851D1 DE8686401739T DE3677851T DE3677851D1 DE 3677851 D1 DE3677851 D1 DE 3677851D1 DE 8686401739 T DE8686401739 T DE 8686401739T DE 3677851 T DE3677851 T DE 3677851T DE 3677851 D1 DE3677851 D1 DE 3677851D1
Authority
DE
Germany
Prior art keywords
saccharomyces
years
generation
increasing
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE8686401739T
Other languages
English (en)
Inventor
Ronald W Ellis
Donna L Montgomery
Loren D Schultz
James R Broach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25065526&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3677851(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of DE3677851D1 publication Critical patent/DE3677851D1/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE8686401739T 1985-08-05 1986-08-04 Verfahren zur steigerung der produktion von rekombinantem protein in hefearten der gattung saccharomyces. Revoked DE3677851D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76259685A 1985-08-05 1985-08-05

Publications (1)

Publication Number Publication Date
DE3677851D1 true DE3677851D1 (de) 1991-04-11

Family

ID=25065526

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686401739T Revoked DE3677851D1 (de) 1985-08-05 1986-08-04 Verfahren zur steigerung der produktion von rekombinantem protein in hefearten der gattung saccharomyces.

Country Status (3)

Country Link
EP (1) EP0211767B1 (de)
JP (1) JPS6232878A (de)
DE (1) DE3677851D1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0277770A1 (de) * 1987-02-02 1988-08-10 Merck & Co. Inc. Alpha-Mating-Faktor-Promotor, modifiziert durch Entfernung der "pre-pro-secretory-leader"-Sequenz
JP2008132832A (ja) * 2006-11-27 2008-06-12 Isuzu Motors Ltd 車両のキャブロック機構

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU584580B2 (en) * 1982-09-08 1989-06-01 Smith Kline - Rit Hepatitis B virus vaccine
CA1341116C (en) * 1983-02-22 2000-10-17 Rae Lyn Burke Yeast expression systems with vectors having gapdh or pyk promoters and synthesis or foreign protein
WO1986007091A1 (en) * 1985-05-21 1986-12-04 Biotechnica International, Inc. Yeast expressing glucoamylase

Also Published As

Publication number Publication date
JPS6232878A (ja) 1987-02-12
EP0211767B1 (de) 1991-03-06
EP0211767A1 (de) 1987-02-25

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8331 Complete revocation