DE3677445D1 - 2-substituierte-e-kondensierte(1,5-c)-pyrimidine, pharmazeutische zubereitungen und ihre verwendung. - Google Patents

2-substituierte-e-kondensierte(1,5-c)-pyrimidine, pharmazeutische zubereitungen und ihre verwendung.

Info

Publication number
DE3677445D1
DE3677445D1 DE8686810421T DE3677445T DE3677445D1 DE 3677445 D1 DE3677445 D1 DE 3677445D1 DE 8686810421 T DE8686810421 T DE 8686810421T DE 3677445 T DE3677445 T DE 3677445T DE 3677445 D1 DE3677445 D1 DE 3677445D1
Authority
DE
Germany
Prior art keywords
pyrimidine
condensed
substituted
pharmaceutical preparations
preparations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686810421T
Other languages
English (en)
Inventor
John E Dr Francis
Karl O Gelotte
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of DE3677445D1 publication Critical patent/DE3677445D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
DE8686810421T 1985-09-30 1986-09-25 2-substituierte-e-kondensierte(1,5-c)-pyrimidine, pharmazeutische zubereitungen und ihre verwendung. Expired - Lifetime DE3677445D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78223485A 1985-09-30 1985-09-30
US84198686A 1986-03-20 1986-03-20

Publications (1)

Publication Number Publication Date
DE3677445D1 true DE3677445D1 (de) 1991-03-14

Family

ID=27119971

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686810421T Expired - Lifetime DE3677445D1 (de) 1985-09-30 1986-09-25 2-substituierte-e-kondensierte(1,5-c)-pyrimidine, pharmazeutische zubereitungen und ihre verwendung.

Country Status (9)

Country Link
EP (1) EP0217748B1 (de)
CA (1) CA1288097C (de)
DE (1) DE3677445D1 (de)
DK (1) DK168046B1 (de)
ES (1) ES2002012A6 (de)
FI (1) FI84068C (de)
GR (1) GR862456B (de)
IE (1) IE58968B1 (de)
PT (1) PT83453B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06104666B2 (ja) * 1986-09-30 1994-12-21 チバ―ガイギー アクチェンゲゼルシャフト ２―置換―ｅ―縮合―〔１，２，４〕トリアゾロ〔１，５―ｃ〕ピリミジン類及びそれを含有する医薬組成物
IE64917B1 (en) * 1988-02-05 1995-09-20 Riker Laboratories Inc Triazolo[1,5-c]pyrimido[1,4]azines as bronchodilators
US5095015A (en) * 1990-07-24 1992-03-10 Neurogen Corporation Certain azacycloalkyl imidazopyrimidines; a new class of gaba brain receptor ligands
US5185446A (en) * 1990-09-04 1993-02-09 Neurogen Corporation Certain cycloalkyl imidazopyrimidines; a new class of gaba brainreceptor ligands
GB9111130D0 (en) * 1991-05-23 1991-07-17 Ici Plc Azole derivatives
GB9111131D0 (en) * 1991-05-23 1991-07-17 Ici Plc Heterocyclic compounds
GB9125002D0 (en) * 1991-11-25 1992-01-22 Ici Plc Azole derivatives
DE4241562A1 (de) * 1992-12-10 1994-06-16 Basf Ag Neue Triazolopyrimidone, ihre Herstellung und Verwendung
IT1264901B1 (it) * 1993-06-29 1996-10-17 Schering Plough S P A Analoghi eterociclici di 1,2,4-triazolo(15-c)pirimidine ad attivita' antagonista per il recettore a2 dell'adenosina
WO1995003806A1 (fr) * 1993-07-27 1995-02-09 Kyowa Hakko Kogyo Co., Ltd. Remede contre la maladie de parkinson
US5494887A (en) * 1994-07-11 1996-02-27 Dowelanco Ring annulated 5-alkoxy-n-aryl[1,2,4]triazolo[1,5-C]-pyrimidine-2-sulfonamide herbicides
US5792766A (en) * 1996-03-13 1998-08-11 Neurogen Corporation Imidazo 1,5-c! quinazolines; a new class of GABA brain receptor ligands
US5955465A (en) * 1996-03-22 1999-09-21 Neurogen Corporation 1,2,4-triazolo 4,3-c!quinazolin-3-ones and 1,2,4-triazolo 4,3-c!quinazolin-3-thiones
US5677309A (en) * 1996-03-22 1997-10-14 Neurogen Corporation 1,2,4-triazolo 4,3-c! quinazolin-3-ones and 1,2,4-triazolo 4,3-c!quinazolin-3-thiones; a new class of GABA brain receptor ligands
EP1069126B1 (de) * 1998-04-03 2003-05-28 Otsuka Pharmaceutical Factory, Inc. Triazolpurin-derivate, medizinische zusammensetzungen die diese enthalten, den adenosin a3 rezeptor kompatibilisierendes mittel und asthma-medikament
ATE293627T1 (de) 2000-05-26 2005-05-15 Schering Corp Adenosin a2a rezeptor antagonisten
PA8539501A1 (es) 2001-02-14 2002-09-30 Warner Lambert Co Compuestos triazolo como inhibidores de mmp
IL160878A0 (en) 2001-10-15 2004-08-31 Schering Corp Imidazo (4,3-e)-1,2,4-triazolo (1,5-c) pyrimidines as adenosine a2a receptor antagonists
US7196106B2 (en) 2002-11-05 2007-03-27 Merck & Co., Inc Cyanothiophene derivatives, compositions containing such compounds and methods of use
EP2861603B1 (de) 2012-06-18 2018-12-19 Dart NeuroScience (Cayman) Ltd 6-Benzyl-6H-pyrido[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5-on und 6-benzyl-[1,2,4]triazolo[1,5-c]pteridin-5(6H)-on-Derivate als PDE1 Inhibitoren zur Behandlung von neurologischen Störungen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3045015A (en) * 1958-10-03 1962-07-17 Ici Ltd Triazolo-[2, 3-c]-pyrimidines
BE792856A (fr) * 1971-12-17 1973-06-15 Sandoz Sa Nouveaux derives de la triazolo-quinazoline, leur preparation et medicaments contenant ces
US4252945A (en) * 1979-07-11 1981-02-24 E. R. Squibb & Sons, Inc. Process for preparing pyrazolo[1,5-c]-quinazoline derivatives and novel intermediates
DE3146599A1 (de) * 1981-11-25 1983-07-07 Basf Ag, 6700 Ludwigshafen Neue triazolochinazoline, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
EP0181282A1 (de) * 1984-10-01 1986-05-14 Ciba-Geigy Ag Triazolochinazolinverbindungen

Also Published As

Publication number Publication date
CA1288097C (en) 1991-08-27
GR862456B (en) 1987-01-29
PT83453B (pt) 1989-05-12
FI84068C (fi) 1991-10-10
EP0217748A3 (en) 1988-01-07
FI863904A (fi) 1987-03-31
IE862575L (en) 1987-03-30
EP0217748B1 (de) 1991-02-06
ES2002012A6 (es) 1988-07-01
DK464386D0 (da) 1986-09-29
DK168046B1 (da) 1994-01-24
EP0217748A2 (de) 1987-04-08
FI863904A0 (fi) 1986-09-26
FI84068B (fi) 1991-06-28
PT83453A (en) 1986-10-01
DK464386A (da) 1987-03-31
IE58968B1 (en) 1993-12-01

Similar Documents

Publication Publication Date Title
DE3582399D1 (de) Purin-derivate und ihre pharmazeutische verwendung.
DE3677445D1 (de) 2-substituierte-e-kondensierte(1,5-c)-pyrimidine, pharmazeutische zubereitungen und ihre verwendung.
NL300038I2 (nl) Thiazolidinedionderivaten, alsmede bereiding en toepassing daarvan.
DE3785312T2 (de) Substituierte tetrahydropyridinoxime und ihre verwendung als cholinergische heilmittel.
DE68921469T2 (de) Peptidderivate und deren verwendung.
DE3580616D1 (de) Mitomycinderivate, ihre herstellung und diese enthaltende pharmazeutische zubereitungen.
DE3689369T2 (de) Terpen-amino-Alkohole und deren medizinische Verwendung.
DE3685170D1 (de) Histaminderivate enthaltende pharmazeutische zusammensetzung.
DE3869167D1 (de) Phenyltriazol-derivate und insectizid.
DK518687A (da) Imidazo-benzoxazinoner, deres fremstilling og laegemidler indholdende forbindelserne
DE3879811T2 (de) Pharmazeutische Zusammensetzung und ihre Verwendung.
DE68910113D1 (de) Wachstuminhibierendes mittel und dessen verwendung.
DE3576118D1 (de) Pharmazeutische praeparate.
DE3881576T2 (de) Anthracyclinderivate und ihre Verwendung.
DE3688864D1 (de) L-phenylalanindehydrogenase und deren verwendung.
DE3766441D1 (de) Anilinotriazine und deren verwendung.
NO874193D0 (no) Farmasoeytiske preparater.
DE3680771D1 (de) Isoxazolopyridophenoxazin- und isothiazolopyridophenoxazinderivate.
DE3883352D1 (de) Muramylpeptid-derivate und ihre verwendung.
DE3668457D1 (de) N-heterocyclosulfonyl-n'-pyrimidinyl-, n'-triazolyl- und n'-triazinyl-harnstoffe.
DE3689036D1 (de) Lankacidinderivate und ihre Herstellung.
DK388986A (da) 7-oxo-4-thia-1-azabicyclo(3.2.0)hept-2-en-derivater, deres fremstillingog anvendelse
ATE60771T1 (de) 2-substituierte-e-kondensierte(1,5-c>-pyrimidin , pharmazeutische zubereitungen und ihre verwendung.
IT8520591A0 (it) Formulazione farmaceutica.
DE3585143D1 (de) Azulenderivate und deren pharmazeutische verwendung.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee