DE3672816D1 - Kontrastmittel fuer nmr-abbildung. - Google Patents
Kontrastmittel fuer nmr-abbildung.Info
- Publication number
- DE3672816D1 DE3672816D1 DE8686905361T DE3672816T DE3672816D1 DE 3672816 D1 DE3672816 D1 DE 3672816D1 DE 8686905361 T DE8686905361 T DE 8686905361T DE 3672816 T DE3672816 T DE 3672816T DE 3672816 D1 DE3672816 D1 DE 3672816D1
- Authority
- DE
- Germany
- Prior art keywords
- contrast agent
- nmr imaging
- nmr
- imaging
- contrast
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002872 contrast media Substances 0.000 title 1
- 238000003384 imaging method Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/20—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations containing free radicals, e.g. trityl radical for overhauser
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
Landscapes
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB858522535A GB8522535D0 (en) | 1985-09-11 | 1985-09-11 | Contrast agent |
PCT/GB1986/000540 WO1987001594A1 (en) | 1985-09-11 | 1986-09-11 | Contrast agent for nmr imaging |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3672816D1 true DE3672816D1 (de) | 1990-08-23 |
Family
ID=10585033
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8686905361T Expired - Lifetime DE3672816D1 (de) | 1985-09-11 | 1986-09-11 | Kontrastmittel fuer nmr-abbildung. |
Country Status (6)
Country | Link |
---|---|
US (1) | US5250672A (de) |
EP (1) | EP0236411B1 (de) |
JP (1) | JPH0714887B2 (de) |
DE (1) | DE3672816D1 (de) |
GB (1) | GB8522535D0 (de) |
WO (1) | WO1987001594A1 (de) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3709851A1 (de) * | 1987-03-24 | 1988-10-06 | Silica Gel Gmbh Adsorptions Te | Nmr-diagnostische fluessigkeitszusammensetzungen |
PH27135A (en) * | 1987-06-23 | 1993-03-16 | Hafslund Nycomed Innovation | Method of electron spin resonance enhanced magnetic resonance imaging |
GB8801646D0 (en) * | 1988-01-26 | 1988-02-24 | Nycomed As | Chemical compounds |
GB8813425D0 (en) * | 1988-06-07 | 1988-07-13 | Hall L D | Magnetic resonance imaging |
GB8817137D0 (en) * | 1988-07-19 | 1988-08-24 | Nycomed As | Compositions |
US5314681A (en) * | 1988-12-23 | 1994-05-24 | Nycomed Innovation Ab | Composition of positive and negative contrast agents for electron spin resonance enhanced magnetic resonance imaging |
US5344640A (en) * | 1991-10-22 | 1994-09-06 | Mallinckrodt Medical, Inc. | Preparation of apatite particles for medical diagnostic imaging |
US5264204A (en) * | 1992-04-30 | 1993-11-23 | Mallinckrodt Medical, Inc. | Hydrophilic free radicals for magnetic resonance imaging |
US5767089A (en) * | 1993-08-16 | 1998-06-16 | Hsia; Jen-Chang | Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules |
US5840701A (en) * | 1993-08-16 | 1998-11-24 | Hsia; Jen-Chang | Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules |
US5804561A (en) * | 1993-08-16 | 1998-09-08 | Hsia; Jen-Chang | Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules |
US5725839A (en) * | 1993-08-16 | 1998-03-10 | Hsia; Jen-Chang | Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules for ERI or MRI |
US5824781A (en) * | 1993-08-16 | 1998-10-20 | Hsia; Jen-Chang | Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules |
US5817632A (en) * | 1993-08-16 | 1998-10-06 | Hsia; Jen-Chang | Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules |
US5741893A (en) * | 1993-08-16 | 1998-04-21 | Hsia; Jen-Chang | Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules |
US5807831A (en) * | 1993-08-16 | 1998-09-15 | Hsia; Jen-Chang | Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules |
TW381022B (en) | 1993-08-16 | 2000-02-01 | Hsia Jen Chang | Compositions and methods utilizing nitroxides to avoid oxygen toxicity, particularly in stabilized, polymerized, conjugated, or encapsulated hemoglobin used as a red cell substitute |
US5863518A (en) * | 1994-10-21 | 1999-01-26 | Nihon Medi-Physics Co., Ltd. | Diagnostic imaging agent with backbone with modified sugar chain end |
US6149891A (en) * | 1995-05-31 | 2000-11-21 | Israel Humanitarian Foundation Ltd. | X-ray contrast medium and method for protecting against harmful effects thereof |
DE19758118A1 (de) * | 1997-12-17 | 1999-07-01 | Schering Ag | Polyrotaxane |
US6113880A (en) * | 1997-12-17 | 2000-09-05 | Schering Aktiengesellschaft | Polyrotaxane derivatives for x-ray and nuclear magnetic resonance imaging |
US6056939A (en) * | 1998-08-28 | 2000-05-02 | Desreux; Jean F. | Self-assembling heteropolymetallic chelates as imaging agents and radiopharmaceuticals |
EP1031354A3 (de) | 1999-01-19 | 2003-02-05 | Rohm And Haas Company | Polymere MRI Kontrastmittel |
NZ519462A (en) * | 1999-12-10 | 2004-03-26 | Gerald M Rosen | Use of poly-nitroxyl-functionalized dendrimers as contrast enhancing agents in MRI imaging of joints |
EP1283728A2 (de) * | 2000-05-23 | 2003-02-19 | Amersham Health AS | Kontrastmitteln |
US20030045461A1 (en) * | 2001-09-06 | 2003-03-06 | Jen-Chang Hsia | Composition and methods of esterified nitroxides gated with carboxylic acids |
US8669236B2 (en) | 2005-05-12 | 2014-03-11 | The General Hospital Corporation | Biotinylated compositions |
US20080038190A1 (en) * | 2006-08-11 | 2008-02-14 | Simpson Thomas J | Composition apparatus and method for use in imaging |
EP2890788A1 (de) | 2012-08-31 | 2015-07-08 | The General Hospital Corporation | Biotinkomplexe zur behandlung und diagnose von morbus alzheimer |
US9718957B2 (en) | 2015-01-30 | 2017-08-01 | International Business Machines Corporation | Biodegradable organic radical-functionalized polycarbonates for medical applications |
US10918742B2 (en) | 2016-03-25 | 2021-02-16 | Nanoprobes, Inc. | Iodine-based particles |
CN114539432A (zh) * | 2022-01-21 | 2022-05-27 | 安徽农业大学 | 一种自旋标记淀粉及其制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3966744A (en) * | 1971-01-11 | 1976-06-29 | Syva Company | Spin labeled compounds |
US3966764A (en) * | 1972-07-10 | 1976-06-29 | Syva Company | Ligand determination of spin labeled compounds by receptor displacement-amphetamine analogs |
DE3129906C3 (de) * | 1981-07-24 | 1996-12-19 | Schering Ag | Paramagnetische Komplexsalze, deren Herstellung und Mittel zur Verwendung bei der NMR-Diagnostik |
GB8413849D0 (en) * | 1984-05-31 | 1984-07-04 | Amersham Int Plc | Nmr contrast agents |
-
1985
- 1985-09-11 GB GB858522535A patent/GB8522535D0/en active Pending
-
1986
- 1986-09-11 DE DE8686905361T patent/DE3672816D1/de not_active Expired - Lifetime
- 1986-09-11 US US07/048,091 patent/US5250672A/en not_active Expired - Fee Related
- 1986-09-11 JP JP61504771A patent/JPH0714887B2/ja not_active Expired - Lifetime
- 1986-09-11 EP EP86905361A patent/EP0236411B1/de not_active Expired - Lifetime
- 1986-09-11 WO PCT/GB1986/000540 patent/WO1987001594A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
EP0236411B1 (de) | 1990-07-18 |
EP0236411A1 (de) | 1987-09-16 |
GB8522535D0 (en) | 1985-10-16 |
WO1987001594A1 (en) | 1987-03-26 |
JPH0714887B2 (ja) | 1995-02-22 |
US5250672A (en) | 1993-10-05 |
JPS63500867A (ja) | 1988-03-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |