DE3672816D1 - Kontrastmittel fuer nmr-abbildung. - Google Patents

Kontrastmittel fuer nmr-abbildung.

Info

Publication number
DE3672816D1
DE3672816D1 DE8686905361T DE3672816T DE3672816D1 DE 3672816 D1 DE3672816 D1 DE 3672816D1 DE 8686905361 T DE8686905361 T DE 8686905361T DE 3672816 T DE3672816 T DE 3672816T DE 3672816 D1 DE3672816 D1 DE 3672816D1
Authority
DE
Germany
Prior art keywords
contrast agent
nmr imaging
nmr
imaging
contrast
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686905361T
Other languages
English (en)
Inventor
John Sadler
Thomas Harding
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guerbet SA
Original Assignee
Guerbet SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guerbet SA filed Critical Guerbet SA
Application granted granted Critical
Publication of DE3672816D1 publication Critical patent/DE3672816D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/20—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations containing free radicals, e.g. trityl radical for overhauser
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DE8686905361T 1985-09-11 1986-09-11 Kontrastmittel fuer nmr-abbildung. Expired - Lifetime DE3672816D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858522535A GB8522535D0 (en) 1985-09-11 1985-09-11 Contrast agent
PCT/GB1986/000540 WO1987001594A1 (en) 1985-09-11 1986-09-11 Contrast agent for nmr imaging

Publications (1)

Publication Number Publication Date
DE3672816D1 true DE3672816D1 (de) 1990-08-23

Family

ID=10585033

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686905361T Expired - Lifetime DE3672816D1 (de) 1985-09-11 1986-09-11 Kontrastmittel fuer nmr-abbildung.

Country Status (6)

Country Link
US (1) US5250672A (de)
EP (1) EP0236411B1 (de)
JP (1) JPH0714887B2 (de)
DE (1) DE3672816D1 (de)
GB (1) GB8522535D0 (de)
WO (1) WO1987001594A1 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3709851A1 (de) * 1987-03-24 1988-10-06 Silica Gel Gmbh Adsorptions Te Nmr-diagnostische fluessigkeitszusammensetzungen
PH27135A (en) * 1987-06-23 1993-03-16 Hafslund Nycomed Innovation Method of electron spin resonance enhanced magnetic resonance imaging
GB8801646D0 (en) * 1988-01-26 1988-02-24 Nycomed As Chemical compounds
GB8813425D0 (en) * 1988-06-07 1988-07-13 Hall L D Magnetic resonance imaging
GB8817137D0 (en) * 1988-07-19 1988-08-24 Nycomed As Compositions
US5314681A (en) * 1988-12-23 1994-05-24 Nycomed Innovation Ab Composition of positive and negative contrast agents for electron spin resonance enhanced magnetic resonance imaging
US5344640A (en) * 1991-10-22 1994-09-06 Mallinckrodt Medical, Inc. Preparation of apatite particles for medical diagnostic imaging
US5264204A (en) * 1992-04-30 1993-11-23 Mallinckrodt Medical, Inc. Hydrophilic free radicals for magnetic resonance imaging
US5767089A (en) * 1993-08-16 1998-06-16 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
US5840701A (en) * 1993-08-16 1998-11-24 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
US5804561A (en) * 1993-08-16 1998-09-08 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
US5725839A (en) * 1993-08-16 1998-03-10 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules for ERI or MRI
US5824781A (en) * 1993-08-16 1998-10-20 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
US5817632A (en) * 1993-08-16 1998-10-06 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
US5741893A (en) * 1993-08-16 1998-04-21 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
US5807831A (en) * 1993-08-16 1998-09-15 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
TW381022B (en) 1993-08-16 2000-02-01 Hsia Jen Chang Compositions and methods utilizing nitroxides to avoid oxygen toxicity, particularly in stabilized, polymerized, conjugated, or encapsulated hemoglobin used as a red cell substitute
US5863518A (en) * 1994-10-21 1999-01-26 Nihon Medi-Physics Co., Ltd. Diagnostic imaging agent with backbone with modified sugar chain end
US6149891A (en) * 1995-05-31 2000-11-21 Israel Humanitarian Foundation Ltd. X-ray contrast medium and method for protecting against harmful effects thereof
DE19758118A1 (de) * 1997-12-17 1999-07-01 Schering Ag Polyrotaxane
US6113880A (en) * 1997-12-17 2000-09-05 Schering Aktiengesellschaft Polyrotaxane derivatives for x-ray and nuclear magnetic resonance imaging
US6056939A (en) * 1998-08-28 2000-05-02 Desreux; Jean F. Self-assembling heteropolymetallic chelates as imaging agents and radiopharmaceuticals
EP1031354A3 (de) 1999-01-19 2003-02-05 Rohm And Haas Company Polymere MRI Kontrastmittel
NZ519462A (en) * 1999-12-10 2004-03-26 Gerald M Rosen Use of poly-nitroxyl-functionalized dendrimers as contrast enhancing agents in MRI imaging of joints
EP1283728A2 (de) * 2000-05-23 2003-02-19 Amersham Health AS Kontrastmitteln
US20030045461A1 (en) * 2001-09-06 2003-03-06 Jen-Chang Hsia Composition and methods of esterified nitroxides gated with carboxylic acids
US8669236B2 (en) 2005-05-12 2014-03-11 The General Hospital Corporation Biotinylated compositions
US20080038190A1 (en) * 2006-08-11 2008-02-14 Simpson Thomas J Composition apparatus and method for use in imaging
EP2890788A1 (de) 2012-08-31 2015-07-08 The General Hospital Corporation Biotinkomplexe zur behandlung und diagnose von morbus alzheimer
US9718957B2 (en) 2015-01-30 2017-08-01 International Business Machines Corporation Biodegradable organic radical-functionalized polycarbonates for medical applications
US10918742B2 (en) 2016-03-25 2021-02-16 Nanoprobes, Inc. Iodine-based particles
CN114539432A (zh) * 2022-01-21 2022-05-27 安徽农业大学 一种自旋标记淀粉及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3966744A (en) * 1971-01-11 1976-06-29 Syva Company Spin labeled compounds
US3966764A (en) * 1972-07-10 1976-06-29 Syva Company Ligand determination of spin labeled compounds by receptor displacement-amphetamine analogs
DE3129906C3 (de) * 1981-07-24 1996-12-19 Schering Ag Paramagnetische Komplexsalze, deren Herstellung und Mittel zur Verwendung bei der NMR-Diagnostik
GB8413849D0 (en) * 1984-05-31 1984-07-04 Amersham Int Plc Nmr contrast agents

Also Published As

Publication number Publication date
EP0236411B1 (de) 1990-07-18
EP0236411A1 (de) 1987-09-16
GB8522535D0 (en) 1985-10-16
WO1987001594A1 (en) 1987-03-26
JPH0714887B2 (ja) 1995-02-22
US5250672A (en) 1993-10-05
JPS63500867A (ja) 1988-03-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee