DE3583830D1 - Nortriptylinderivate, verfahren zu ihrer herstellung, deren konjugate mit antigenischen proteinen und enzymen, antikoerper davon und verwandte verfahren zur bestimmung. - Google Patents

Nortriptylinderivate, verfahren zu ihrer herstellung, deren konjugate mit antigenischen proteinen und enzymen, antikoerper davon und verwandte verfahren zur bestimmung.

Info

Publication number
DE3583830D1
DE3583830D1 DE8585303601T DE3583830T DE3583830D1 DE 3583830 D1 DE3583830 D1 DE 3583830D1 DE 8585303601 T DE8585303601 T DE 8585303601T DE 3583830 T DE3583830 T DE 3583830T DE 3583830 D1 DE3583830 D1 DE 3583830D1
Authority
DE
Germany
Prior art keywords
determination
conjugates
nortriptyline
antibodies
enzymes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8585303601T
Other languages
English (en)
Inventor
Mae Wan-Leng Hu
Prithipal Singh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Application granted granted Critical
Publication of DE3583830D1 publication Critical patent/DE3583830D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9466Antidepressants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pyrrole Compounds (AREA)
DE8585303601T 1984-05-23 1985-05-22 Nortriptylinderivate, verfahren zu ihrer herstellung, deren konjugate mit antigenischen proteinen und enzymen, antikoerper davon und verwandte verfahren zur bestimmung. Expired - Lifetime DE3583830D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/613,709 US4795822A (en) 1984-05-23 1984-05-23 Nortriptyline conjugates to antigenic proteins and enzymes

Publications (1)

Publication Number Publication Date
DE3583830D1 true DE3583830D1 (de) 1991-09-26

Family

ID=24458404

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585303601T Expired - Lifetime DE3583830D1 (de) 1984-05-23 1985-05-22 Nortriptylinderivate, verfahren zu ihrer herstellung, deren konjugate mit antigenischen proteinen und enzymen, antikoerper davon und verwandte verfahren zur bestimmung.

Country Status (6)

Country Link
US (1) US4795822A (de)
EP (1) EP0167256B1 (de)
JP (3) JPH0689039B2 (de)
AT (1) ATE66534T1 (de)
CA (1) CA1279592C (de)
DE (1) DE3583830D1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601141A1 (fr) * 1986-07-02 1988-01-08 Centre Nat Rech Scient Produit de couplage a base d'haptene, utile notamment comme substance immunogene, anticorps correspondants et applications
US5407835A (en) * 1991-07-31 1995-04-18 Abbott Laboratories Reagents and methods for the quantification of amitriptyline or nortriptyline in biological fluids
US6803040B1 (en) * 1995-08-22 2004-10-12 Biosite, Inc. Derivatives of tricyclic antidepressants and protein and polypeptide tricyclic antidepressant derivative conjugates and labels
US6368814B1 (en) * 2000-12-22 2002-04-09 Roche Diagnostics Corporation Tricyclic antidepressant derivatives and immunoassay

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2412700A (en) * 1944-06-10 1946-12-17 Eastman Kodak Co Thioglycolic amides
FR1368709A (fr) * 1959-10-27 1964-08-07 Merck & Co Inc Dérivés du dibenzo [a, d] [1, 4] cycloheptadiène
BR6461109D0 (pt) * 1963-07-25 1973-07-19 Merck & Co Inc Processos de preparacao de derivados de dibenzo ciclo heptenos
CA890423A (en) * 1968-11-08 1972-01-11 A. Davis Martin Process for preparing dibenzo (a,d)-cycloheptene derivatives
CA875549A (en) 1968-12-03 1971-07-13 Ayerst, Mckenna And Harrison Limited Process for preparing amitriptyline and related compounds
CH541545A (de) * 1970-10-09 1973-09-15 Hoffmann La Roche Verfahren zur Herstellung von tricyclischen Iminen
US4329502A (en) * 1978-08-28 1982-05-11 Syva Company Propranolol antigen conjugates and antibodies
US4241177A (en) * 1978-08-28 1980-12-23 Syva Company Propanolol antigen conjugates and antibodies
US4223013A (en) * 1978-12-29 1980-09-16 Syva Company Amitriptyline conjugates to antigenic proteins and enzymes
US4307245A (en) * 1978-12-29 1981-12-22 Syva Company Amitriptyline conjugates to antigenic proteins and enzymes
US4495281A (en) * 1982-10-21 1985-01-22 Miles Laboratories, Inc. Tricyclic antidepressant drug immunogens, antibodies, labeled conjugates, and related derivatives

Also Published As

Publication number Publication date
US4795822A (en) 1989-01-03
JP2609083B2 (ja) 1997-05-14
EP0167256B1 (de) 1991-08-21
JP2526359B2 (ja) 1996-08-21
JPS6141A (ja) 1986-01-06
JPH08105894A (ja) 1996-04-23
CA1279592C (en) 1991-01-29
JPH06201694A (ja) 1994-07-22
ATE66534T1 (de) 1991-09-15
EP0167256A1 (de) 1986-01-08
JPH0689039B2 (ja) 1994-11-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Free format text: BARZ, P., DIPL.-CHEM. DR.RER.NAT., PAT.-ANW., 80803 MUENCHEN