DE3582649D1 - Magnetisch empfindlicher reagenstraeger und verfahren zur herstellung. - Google Patents

Magnetisch empfindlicher reagenstraeger und verfahren zur herstellung.

Info

Publication number
DE3582649D1
DE3582649D1 DE8585307513T DE3582649T DE3582649D1 DE 3582649 D1 DE3582649 D1 DE 3582649D1 DE 8585307513 T DE8585307513 T DE 8585307513T DE 3582649 T DE3582649 T DE 3582649T DE 3582649 D1 DE3582649 D1 DE 3582649D1
Authority
DE
Germany
Prior art keywords
production
magnetically sensitive
sensitive reagent
reagent
magnetically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8585307513T
Other languages
English (en)
Inventor
Beri Cohen
Tak K Wong
Bartholomew Hargitay
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Technicon Instruments Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technicon Instruments Corp filed Critical Technicon Instruments Corp
Application granted granted Critical
Publication of DE3582649D1 publication Critical patent/DE3582649D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/005—Pretreatment specially adapted for magnetic separation
    • B03C1/01—Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/14—Enzymes or microbial cells immobilised on or in an inorganic carrier
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/5434—Magnetic particles using magnetic particle immunoreagent carriers which constitute new materials per se
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545—Synthetic resin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/10—Magnetic particle immunoreagent carriers the magnetic material being used to coat a pre-existing polymer particle but not being present in the particle core
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/20—Magnetic particle immunoreagent carriers the magnetic material being present in the particle core

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Inorganic Chemistry (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Soft Magnetic Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE8585307513T 1984-11-01 1985-10-17 Magnetisch empfindlicher reagenstraeger und verfahren zur herstellung. Expired - Fee Related DE3582649D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US66751484A 1984-11-01 1984-11-01

Publications (1)

Publication Number Publication Date
DE3582649D1 true DE3582649D1 (de) 1991-05-29

Family

ID=24678527

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585307513T Expired - Fee Related DE3582649D1 (de) 1984-11-01 1985-10-17 Magnetisch empfindlicher reagenstraeger und verfahren zur herstellung.

Country Status (5)

Country Link
EP (1) EP0180384B1 (de)
JP (1) JP2554250B2 (de)
AU (1) AU595165B2 (de)
CA (1) CA1314769C (de)
DE (1) DE3582649D1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770459A (en) * 1986-04-30 1998-06-23 Igen International, Inc. Methods and apparatus for improved luminescence assays using particle concentration, electrochemical generation of chemiluminescence detection
JPH0737989B2 (ja) * 1986-07-04 1995-04-26 東ソー株式会社 免疫反応の測定方法および装置
US6881589B1 (en) 1987-04-30 2005-04-19 Bioveris Corporation Electrochemiluminescent localizable complexes for assay compositions
US5935779A (en) * 1988-11-03 1999-08-10 Igen International Inc. Methods for improved particle electrochemiluminescence assay
US4921809A (en) * 1987-09-29 1990-05-01 Findley Adhesives, Inc. Polymer coated solid matrices and use in immunoassays
US5962218A (en) * 1988-11-03 1999-10-05 Igen International Inc. Methods and apparatus for improved luminescence assays
US5705402A (en) * 1988-11-03 1998-01-06 Igen International, Inc. Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets
US5798083A (en) * 1988-11-03 1998-08-25 Igen International, Inc. Apparatus for improved luminescence assays using particle concentration and chemiluminescence detection
US5746974A (en) * 1988-11-03 1998-05-05 Igen International, Inc. Apparatus for improved luminescence assays using particle concentration, electrochemical generation of chemiluminescence and chemiluminescence detection
US5779976A (en) * 1988-11-03 1998-07-14 Igen International, Inc. Apparatus for improved luminescence assays
WO1991009678A1 (en) * 1989-12-22 1991-07-11 Omni Quest Corporation Organo-metallic coated particles for use in separations
ZA92804B (en) 1991-02-06 1992-12-30 Igen Inc Methods and apparatus for improved luminescence assays
WO1996000394A1 (en) * 1994-06-23 1996-01-04 Ciba Corning Diagnostics Corp. Process for the preparation of magnetic particles used in biological analyses
US5744367A (en) * 1994-11-10 1998-04-28 Igen International, Inc. Magnetic particle based electrochemiluminescent detection apparatus and method
DE19508772C2 (de) * 1995-03-01 1998-01-29 Schering Ag Verfahren und Verbindungen zur Detektion von Analyten mittels Remanenzmessung und deren Verwendung
AU5920696A (en) * 1995-05-18 1996-11-29 Igen, Inc. Method for derivitizing electrodes and assay methods using s uch derivitized electrodes
DE69815282T2 (de) 1997-12-25 2004-05-06 Tosoh Corp., Shinnanyo Magnetischer Träger, seine Herstellung, und Verfahren zum Extrahieren von Nukleinsäuren
JP2002517085A (ja) * 1998-05-26 2002-06-11 バー−イラン ユニバーシティ 磁性金属酸化物ナノ粒子の核生成および成長ならびにその使用
FR2800635B1 (fr) 1999-11-05 2002-07-26 Bio Merieux Nanospheres composites, conjugues derives, procede de preparation et leurs utilisations
FR2800636A1 (fr) * 1999-11-05 2001-05-11 Bio Merieux Particules composites, conjugues derives, leur procede de preparation et utilisations
AU6380001A (en) * 2000-03-24 2001-10-03 Qiagen Gmbh Porous ferro- or ferrimagnetic glass particles for isolating molecules
EP1160206A1 (de) * 2000-05-31 2001-12-05 Nisshinbo Industries, Inc. Träger für Mikroorganismen, Verfahren zur Herstellung des Trägers und Verfahren zu dessen Verwendung
EP1893990B1 (de) 2005-06-03 2018-05-02 Board of Regents of the University of Texas System Elektrochemie und elektrogenerierte chemolumineszenz mit einer faradayschen einzelelektrode
JPWO2007126151A1 (ja) * 2006-04-28 2009-09-17 日立マクセル株式会社 機能性粒子およびそれを用いた標的物質の分離方法
WO2010089138A1 (en) 2009-02-09 2010-08-12 Caprotec Bioanalytics Gmbh Devices, systems and methods for separating magnetic particles
CN103116026B (zh) * 2013-01-29 2015-04-15 南昌大学 一种基于Fe3O4纳米材料免疫磁分离的食源性致病菌快速检测方法
PT107379A (pt) * 2013-12-23 2015-10-13 Faculdade De Ciências E Tecnologia Da Universidade Nova De Lisboa Extração líquido-líquido magnética para a purificação e separação de substâncias

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2334106A1 (fr) * 1975-12-02 1977-07-01 Pasteur Institut Gel magnetique convenant pour dosages immunoenzymatiques
GB1575805A (en) * 1976-03-12 1980-10-01 Technicon Instr Automatic diagnostic apparatus
US4115534A (en) * 1976-08-19 1978-09-19 Minnesota Mining And Manufacturing Company In vitro diagnostic test
US4169804A (en) * 1976-08-19 1979-10-02 Minnesota Mining And Manufacturing Company Magnetically responsive composite microparticle
AU527144B2 (en) * 1978-02-13 1983-02-17 Technicon Instruments Corportion Magnetically attractable material
US4297337A (en) * 1979-04-13 1981-10-27 Corning Glass Works Solid-phase immunoassays using magnetic glass
US4452773A (en) * 1982-04-05 1984-06-05 Canadian Patents And Development Limited Magnetic iron-dextran microspheres
NO155316C (no) * 1982-04-23 1987-03-11 Sintef Fremgangsmaate for fremstilling av magnetiske polymerpartikler.
JPS59195161A (ja) * 1983-04-21 1984-11-06 Fujirebio Inc 磁性粒子及びその製造法
JPS6055265A (ja) * 1983-09-06 1985-03-30 Fujirebio Inc 磁性粒子を用いた抗原、抗体の測定方法

Also Published As

Publication number Publication date
JP2554250B2 (ja) 1996-11-13
JPS61181967A (ja) 1986-08-14
EP0180384B1 (de) 1991-04-24
AU595165B2 (en) 1990-03-29
EP0180384A3 (en) 1987-09-30
CA1314769C (en) 1993-03-23
AU4902985A (en) 1986-05-08
EP0180384A2 (de) 1986-05-07

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee