DE3578786D1 - Als sonden zum nachweis von schaedlichen, in chromosom-dns enthaltenen genen zu verwendende deoxyribonukleinsaeuremolekuele. - Google Patents
Als sonden zum nachweis von schaedlichen, in chromosom-dns enthaltenen genen zu verwendende deoxyribonukleinsaeuremolekuele.Info
- Publication number
- DE3578786D1 DE3578786D1 DE8585300065T DE3578786T DE3578786D1 DE 3578786 D1 DE3578786 D1 DE 3578786D1 DE 8585300065 T DE8585300065 T DE 8585300065T DE 3578786 T DE3578786 T DE 3578786T DE 3578786 D1 DE3578786 D1 DE 3578786D1
- Authority
- DE
- Germany
- Prior art keywords
- deoxyribonucleic acid
- acid molecule
- detecting
- damagous
- chromosome
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/571,911 US4681840A (en) | 1984-01-18 | 1984-01-18 | Deoxyribonucleic acid molecules useful as probes for detecting oncogenes incorporated into chromosomal DNA |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3578786D1 true DE3578786D1 (de) | 1990-08-30 |
Family
ID=24285562
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8585300065T Expired - Lifetime DE3578786D1 (de) | 1984-01-18 | 1985-01-04 | Als sonden zum nachweis von schaedlichen, in chromosom-dns enthaltenen genen zu verwendende deoxyribonukleinsaeuremolekuele. |
Country Status (9)
Country | Link |
---|---|
US (1) | US4681840A (de) |
EP (1) | EP0152999B1 (de) |
JP (2) | JPS61501203A (de) |
AT (1) | ATE54943T1 (de) |
AU (1) | AU580753B2 (de) |
CA (1) | CA1240629A (de) |
DE (1) | DE3578786D1 (de) |
DK (1) | DK173700B1 (de) |
WO (1) | WO1985003297A1 (de) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL76997A0 (en) * | 1984-11-14 | 1986-04-29 | Oncogene Science Inc | Probes and methods useful for detecting chromosomal translocation |
US5721098A (en) * | 1986-01-16 | 1998-02-24 | The Regents Of The University Of California | Comparative genomic hybridization |
US5447841A (en) | 1986-01-16 | 1995-09-05 | The Regents Of The Univ. Of California | Methods for chromosome-specific staining |
US6280929B1 (en) | 1986-01-16 | 2001-08-28 | The Regents Of The University Of California | Method of detecting genetic translocations identified with chromosomal abnormalities |
US6872817B1 (en) | 1986-01-16 | 2005-03-29 | The Regents Of The Univ. Of California | Method of staining target interphase chromosomal DNA |
US7115709B1 (en) * | 1986-01-16 | 2006-10-03 | The Regents Of The University Of California | Methods of staining target chromosomal DNA employing high complexity nucleic acid probes |
US6475720B1 (en) | 1986-01-16 | 2002-11-05 | The Regents Of The University Of California | Chromosome-specific staining to detect genetic rearrangements associated with chromosome 3 and/or chromosome 17 |
US5756696A (en) * | 1986-01-16 | 1998-05-26 | Regents Of The University Of California | Compositions for chromosome-specific staining |
US5066792A (en) * | 1987-09-04 | 1991-11-19 | Board Of Regents University Of Texas | Gene probe for detection of specific human leukemias |
US4874853A (en) * | 1988-04-18 | 1989-10-17 | City Of Hope | Synthetic oligonucleotides useful in diagnosis of chronic myelogenous leukemia |
US5057410A (en) * | 1988-08-05 | 1991-10-15 | Cetus Corporation | Chimeric messenger RNA detection methods |
JPH02109982A (ja) * | 1988-10-18 | 1990-04-23 | Teijin Ltd | 遺伝子断片,プローブ及びそれを用いる染色体異常検出方法 |
US6203977B1 (en) * | 1988-11-15 | 2001-03-20 | Yale University | Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization |
US5075217A (en) * | 1989-04-21 | 1991-12-24 | Marshfield Clinic | Length polymorphisms in (dC-dA)n ·(dG-dT)n sequences |
US8592155B2 (en) * | 1989-07-19 | 2013-11-26 | The Regents Of The University Of California | Method of detecting genetic deletions identified with chromosomal abnormalities |
US5851764A (en) * | 1990-10-25 | 1998-12-22 | The Trustees Of Columbia University In The City Of New York | Human prostate tumor inducing gene-1 and uses thereof |
US6159751A (en) * | 1990-10-25 | 2000-12-12 | The Trustees Of Columbia University In The City Of New York | Development of DNA probes and immunological reagents of human tumor associated antigens |
JP3256227B2 (ja) * | 1990-10-25 | 2002-02-12 | ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク | Dnaプローブの開発およびヒト腫瘍関連抗原の免疫学的試薬 |
WO1992016660A1 (en) * | 1991-03-22 | 1992-10-01 | Sloan-Kettering Institute For Cancer Research | Methods for detection and treatment of cancer |
CA2103377A1 (en) * | 1991-06-18 | 1992-12-19 | Bruno Calabretta | Selective inhibition of leukemic cell proliferation by bcr-abl antisense oligonucleotides |
US6025126A (en) | 1991-10-28 | 2000-02-15 | Arch Development Corporation | Methods and compositions for the detection of chromosomal aberrations |
US7534567B2 (en) * | 1992-03-04 | 2009-05-19 | The Regents Of The University Of California | Detection of nucleic acid sequence differences by comparative genomic hybridization |
DE69330750T2 (de) * | 1992-03-04 | 2002-07-04 | Univ California | Vergleichende genomhybridisierung |
US5976790A (en) * | 1992-03-04 | 1999-11-02 | The Regents Of The University Of California | Comparative Genomic Hybridization (CGH) |
US6689561B1 (en) * | 1994-04-14 | 2004-02-10 | The Regents Of The University Of California | Tumor suppressor gene and methods for detection of cancer, monitoring of tumor progression and cancer treatment |
US6689864B1 (en) * | 1994-04-14 | 2004-02-10 | The Regents Of The University Of California | Cyclin dependent kinase 4 inhibitor |
US5639600A (en) * | 1994-08-05 | 1997-06-17 | The Regents Of The University Of California | Diagnosis and treatment of cell proliferative disease having clonal macrophage involvement |
US5830645A (en) * | 1994-12-09 | 1998-11-03 | The Regents Of The University Of California | Comparative fluorescence hybridization to nucleic acid arrays |
US6007994A (en) * | 1995-12-22 | 1999-12-28 | Yale University | Multiparametric fluorescence in situ hybridization |
EP0878552A1 (de) * | 1997-05-13 | 1998-11-18 | Erasmus Universiteit Rotterdam | Molekularer Nachweis von chromosomalen Veränderungen |
US6849400B1 (en) | 1997-07-23 | 2005-02-01 | Gen-Probe Incorporated | Methods for detecting and measuring spliced nucleic acids |
ATE423622T1 (de) | 1998-05-01 | 2009-03-15 | Gen Probe Inc | Automatisches isolierungs- und amplifizierungsverfahren für eine zielnukleinsäuresequenz |
EP1078098A1 (de) * | 1998-05-04 | 2001-02-28 | Dako A/S | Verfahren und sonden zur detektion chromosomaler aberrationen |
WO2002093130A2 (en) * | 2001-05-14 | 2002-11-21 | Cancer Genetics, Inc. | Methods of analyzing chromosomal translocations using fluorescence in situ hybridization (fish) |
WO2005079474A2 (en) * | 2004-02-17 | 2005-09-01 | The Regents Of The University Of California | Detection of nucleic acid sequence differences by comparative genomic hybridization |
EP2322940B1 (de) | 2005-03-10 | 2014-10-29 | Gen-Probe Incorporated | Systeme und Verfahren zur Durchführung von Tests zum Nachweis oder zur Quantifizierung von Analyten in Proben |
EP1909108B1 (de) | 2005-03-10 | 2019-05-29 | Gen-Probe Incorporated | Systeme und Verfahren zur Durchführung von Tests zum Nachweis oder zur Quantifizierung von Analyten |
KR100902081B1 (ko) * | 2007-05-15 | 2009-06-09 | 삼성전자주식회사 | 탄소 나노튜브의 전극 사이 배치 방법, 탄소나노튜브-탐식자 복합체를 이용한 생체분자 검출 장치와 그방법 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4535058A (en) * | 1982-10-01 | 1985-08-13 | Massachusetts Institute Of Technology | Characterization of oncogenes and assays based thereon |
US4490472A (en) * | 1982-06-17 | 1984-12-25 | Imreg, Inc. | Sensitive tests for malignancies based on DNA detection |
US4542096A (en) * | 1983-02-25 | 1985-09-17 | President And Fellows Of Harvard College | Detecting rearranged human c-myc DNA fragments associated with oncogenes |
-
1984
- 1984-01-18 US US06/571,911 patent/US4681840A/en not_active Expired - Lifetime
-
1985
- 1985-01-04 EP EP85300065A patent/EP0152999B1/de not_active Expired - Lifetime
- 1985-01-04 AT AT85300065T patent/ATE54943T1/de not_active IP Right Cessation
- 1985-01-04 DE DE8585300065T patent/DE3578786D1/de not_active Expired - Lifetime
- 1985-01-08 JP JP60500519A patent/JPS61501203A/ja active Pending
- 1985-01-08 CA CA000471634A patent/CA1240629A/en not_active Expired
- 1985-01-08 WO PCT/US1985/000014 patent/WO1985003297A1/en unknown
- 1985-01-08 AU AU38802/85A patent/AU580753B2/en not_active Expired
- 1985-09-17 DK DK198504204A patent/DK173700B1/da not_active IP Right Cessation
-
1997
- 1997-01-14 JP JP9017432A patent/JPH09308485A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0152999A2 (de) | 1985-08-28 |
JPH09308485A (ja) | 1997-12-02 |
EP0152999B1 (de) | 1990-07-25 |
ATE54943T1 (de) | 1990-08-15 |
JPS61501203A (ja) | 1986-06-19 |
DK173700B1 (da) | 2001-07-02 |
AU3880285A (en) | 1985-08-09 |
DK420485D0 (da) | 1985-09-17 |
US4681840A (en) | 1987-07-21 |
WO1985003297A1 (en) | 1985-08-01 |
CA1240629A (en) | 1988-08-16 |
EP0152999A3 (en) | 1985-10-09 |
AU580753B2 (en) | 1989-02-02 |
DK420485A (da) | 1985-09-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |