DE3576498D1 - 2-sulfamoyl-1h-indole-derivate zur behandlung von hohem intraocularem druck. - Google Patents

2-sulfamoyl-1h-indole-derivate zur behandlung von hohem intraocularem druck.

Info

Publication number
DE3576498D1
DE3576498D1 DE8585400439T DE3576498T DE3576498D1 DE 3576498 D1 DE3576498 D1 DE 3576498D1 DE 8585400439 T DE8585400439 T DE 8585400439T DE 3576498 T DE3576498 T DE 3576498T DE 3576498 D1 DE3576498 D1 DE 3576498D1
Authority
DE
Germany
Prior art keywords
sulfamoyl
intraocular pressure
indole derivatives
treating high
high intraocular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8585400439T
Other languages
English (en)
Inventor
Kenneth L Shepard
Samuel L Graham
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of DE3576498D1 publication Critical patent/DE3576498D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE8585400439T 1984-03-14 1985-03-07 2-sulfamoyl-1h-indole-derivate zur behandlung von hohem intraocularem druck. Expired - Fee Related DE3576498D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US58938584A 1984-03-14 1984-03-14

Publications (1)

Publication Number Publication Date
DE3576498D1 true DE3576498D1 (de) 1990-04-19

Family

ID=24357786

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585400439T Expired - Fee Related DE3576498D1 (de) 1984-03-14 1985-03-07 2-sulfamoyl-1h-indole-derivate zur behandlung von hohem intraocularem druck.

Country Status (3)

Country Link
EP (1) EP0155214B1 (de)
JP (1) JPH0625105B2 (de)
DE (1) DE3576498D1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0189690B1 (de) * 1984-12-12 1989-03-01 Merck & Co. Inc. Substituierte aromatische Sulfonamide, ihre Herstellung und diese enthaltende ophthalmische Zubereitungen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR241136A1 (es) * 1981-07-13 1991-11-29 Merck E Co Inc Procedimiento para preparar esteres de 6-hidroxi-2-benzotiazolsulfonamida para tratamiento topicode presion intraocular elevada"
BR8204028A (pt) * 1981-07-16 1983-07-05 Du Pont Composto herbicida composicao adequada e processo para controlar o crescimento de vegetacao indesejada
US4386098A (en) * 1981-11-03 1983-05-31 Merck & Co., Inc. 6-Hydroxy-2-benzothiazolesulfonamide for the topical treatment of elevated intraocular pressure

Also Published As

Publication number Publication date
EP0155214A2 (de) 1985-09-18
JPS60204760A (ja) 1985-10-16
JPH0625105B2 (ja) 1994-04-06
EP0155214A3 (en) 1986-02-12
EP0155214B1 (de) 1990-03-14

Similar Documents

Publication Publication Date Title
DE3584013D1 (de) Zubereitung zur behandlung von psoriasis.
DE68907909D1 (de) Praeparat zur behandlung von erektionsstoerungen.
DE3581514D1 (de) Film zur behandlung von halbleiterwaffeln.
DE3580918D1 (de) Anordnung zur behandlung von bildern.
ES520195A0 (es) Procedimiento para preparar nuevos derivados de 3-ceto- 4,9,19-nor-esteroides.
DE3769066D1 (de) Hydantoin-derivate zur behandlung von komplikationen bei diabetes.
DE3579419D1 (de) Einstufiges hydrobehandlungsverfahren.
NO903449D0 (no) Fremgangsmaate for aa behandle underjordiske formasjoner.
DE68919629D1 (de) Verfahren zum Herstellen von selbstjustierendem Wolframlsilizid.
DE3584538D1 (de) Verfahren zur behandlung von textilien.
DE68903208D1 (de) Verfahren zur thermischen behandlung von laktoferrin.
DE3770361D1 (de) Azolderivate, geeignet zur bekaempfung von pflanzen-krankheiten.
IS2902A7 (is) Aðferð til framleiðslu á 1,8-dihydroxy-10-acyl-9-anthrones, sérstaklega til meðferðar á psoriasis
BA97167B1 (bs) Postupak za pripravu 7,16-dioksa-2 aza-10-0-kladinozil-12-0 desozaminil-4,5-dihidroksi-6-etil 3,5,9,11,13,15-heksametilbiciklo (11.2.1)heksadeka-1 (2)-en-8-ona
PT80152A (de) Methode zur behandlung des glaukoms vok
IT1209526B (it) Metodo per il trattamento enzimatico di polpa pre-spremuta.
ATE6255T1 (de) Verfahren zur herstellung von 2,3,5trichlorpyridin.
HUT36783A (en) Process for preparing 1,7-diphenyl-3-methyl-aza-7-cyano-8-methyl-nonane
DE58901165D1 (de) Verfahren zur herstellung von 2,4-dihydroxybenzoesaeure.
DE3576498D1 (de) 2-sulfamoyl-1h-indole-derivate zur behandlung von hohem intraocularem druck.
DE3280210D1 (de) Vorratskathode und verfahren zum herstellen derselben.
ATE41927T1 (de) Phenylalkylamine - bioregulatoren.
ATE9800T1 (de) Verfahren zur herstellung von 4-amino-6tert.butyl-3-mercapto-1,2,4-triazin-5-on.
DE68907914D1 (de) Verfahren zur behandlung von brandwunden.
IT8321507A0 (it) Procedimento di preparazione fermentativa di l-leucina.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee