DE355415C - Process for the production of durable serum and lymph preparations - Google Patents
Process for the production of durable serum and lymph preparationsInfo
- Publication number
- DE355415C DE355415C DEC28511D DEC0028511D DE355415C DE 355415 C DE355415 C DE 355415C DE C28511 D DEC28511 D DE C28511D DE C0028511 D DEC0028511 D DE C0028511D DE 355415 C DE355415 C DE 355415C
- Authority
- DE
- Germany
- Prior art keywords
- lymph
- durable
- preparations
- serum
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Description
Verfahren zur Herstellung haltbarer Serum- und Lymphepräparate. Die Konservierung von Heilseren und Lymphe wurde bisher durch Zusatz von Phenolen bzw. Glyzerin erstrebt.Process for the production of durable serum and lymph preparations. the Preservation of healing serums and lymph has so far been achieved by adding phenols or Aspires to glycerine.
Es wurde gefunden, daß dieses Ziel durch Zugabe geringer Mengen von Akridinfarbstoffen, wie Trypaflavin u: dgl. besser und sicherer als durch die bisherigen Verfahren erreicht wird. Die konservierende bzw. desinfizierende Kraft der Akridinfarbstoffe ist eine weit höhere als die der genannten Substanzen, die Wirksamkeit der Seren und Lymphen wird durch sie nicht beeinträchtigt, und außerdem sind bei Anwendung dieser Farbstoffe schädliche Nebenwirkungen ausgeschlossen, da sie im Gegensatz zu den Phenolen ungiftig sind. Beispiel: Zur Darstellung von Pockenimpfstoff wird der Kälberrohstoff mit der drei- bis fünffachen Menge sterilisierter iprozentiger Lösung von 3-6-Diamino-io-methylakridiniumcblorid (Neutral-Trypaflavin) vermischt und in üblicher Weise weiterverarbeitet. Die Trypaflavinlymphe unterscheidet sich in ihrem Äußeren von der Glyzerinlymphe durch ihre grüne Farbe und durch ihre dünnflüssige Konsistenz.It has been found that this goal is achieved by adding small amounts of Acridine dyes, such as trypaflavin and the like. Better and safer than the previous ones Procedure is achieved. The preserving or disinfecting power of acridine dyes is a much higher than that of the substances mentioned, the effectiveness of the serums and lymph is not affected by them, and besides, are in application these dyes ruled out harmful side effects as opposed to them are non-toxic to phenols. Example: To represent smallpox vaccine is the calf raw material with three to five times the amount of sterilized I% Solution of 3-6-diamino-io-methylakridiniumcblorid (neutral trypaflavin) mixed and processed in the usual way. The trypaflavin lymph is different in its exterior from the glycerine lymph through its green color and its thin liquid Consistency.
Claims (1)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEC28511D DE355415C (en) | 1919-11-21 | 1919-11-21 | Process for the production of durable serum and lymph preparations |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEC28511D DE355415C (en) | 1919-11-21 | 1919-11-21 | Process for the production of durable serum and lymph preparations |
Publications (1)
Publication Number | Publication Date |
---|---|
DE355415C true DE355415C (en) | 1922-06-26 |
Family
ID=7018664
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DEC28511D Expired DE355415C (en) | 1919-11-21 | 1919-11-21 | Process for the production of durable serum and lymph preparations |
Country Status (1)
Country | Link |
---|---|
DE (1) | DE355415C (en) |
-
1919
- 1919-11-21 DE DEC28511D patent/DE355415C/en not_active Expired
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