DE3381040D1 - Verfahren zur trennung von alpha-1-proteinase aus blutplasmafraktionen. - Google Patents

Verfahren zur trennung von alpha-1-proteinase aus blutplasmafraktionen.

Info

Publication number
DE3381040D1
DE3381040D1 DE8383105539T DE3381040T DE3381040D1 DE 3381040 D1 DE3381040 D1 DE 3381040D1 DE 8383105539 T DE8383105539 T DE 8383105539T DE 3381040 T DE3381040 T DE 3381040T DE 3381040 D1 DE3381040 D1 DE 3381040D1
Authority
DE
Germany
Prior art keywords
proteinase
blood plasma
plasma fractions
separating alpha
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8383105539T
Other languages
English (en)
Inventor
Michael H Coan
William J Brockway
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/389,202 external-priority patent/US4379087A/en
Application filed by Miles Inc filed Critical Miles Inc
Application granted granted Critical
Publication of DE3381040D1 publication Critical patent/DE3381040D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8125—Alpha-1-antitrypsin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum
    • Y10S530/831—Cohn fractions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE8383105539T 1982-06-17 1983-06-06 Verfahren zur trennung von alpha-1-proteinase aus blutplasmafraktionen. Expired - Lifetime DE3381040D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/389,202 US4379087A (en) 1982-06-17 1982-06-17 Method of preparing alpha-1-proteinase inhibitor
US06/461,422 US4439358A (en) 1982-06-17 1983-01-27 Method of preparing alpha-1-proteinase inhibitor

Publications (1)

Publication Number Publication Date
DE3381040D1 true DE3381040D1 (de) 1990-02-08

Family

ID=27012590

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383105539T Expired - Lifetime DE3381040D1 (de) 1982-06-17 1983-06-06 Verfahren zur trennung von alpha-1-proteinase aus blutplasmafraktionen.

Country Status (3)

Country Link
US (1) US4439358A (de)
EP (1) EP0097274B1 (de)
DE (1) DE3381040D1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4496689A (en) * 1983-12-27 1985-01-29 Miles Laboratories, Inc. Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
US4684723A (en) * 1985-09-11 1987-08-04 Miles Laboratories, Inc. Method of separating proteins from aqueous solutions
US4656254A (en) * 1985-12-02 1987-04-07 Miles Laboratories, Inc. Method of preparing alpha-1-proteinase inhibitor and antithrombin III
EP0288841B1 (de) * 1987-04-27 1992-12-30 Miles Inc. Verfahren zur Herstellung von hochgereinigtem alpha-1-Proteinase-Inhibitor
US5151358A (en) * 1989-06-13 1992-09-29 Genencor International, Inc. Processes for the recovery of naturally produced chymosin
US5139943A (en) * 1989-06-13 1992-08-18 Genencor International, Inc. Processes for the recovery of microbially produced chymosin
US5290474A (en) * 1990-10-05 1994-03-01 Genencor International, Inc. Detergent composition for treating cotton-containing fabrics containing a surfactant and a cellulase composition containing endolucanase III from trichoderma ssp
CA2093422C (en) * 1990-10-05 2001-04-03 DETERGENT COMPOSITIONS CONTAINING LOW CBH I CONTENT CELLULASE COMPOSITIONS
US5328841A (en) * 1990-10-05 1994-07-12 Genencor International, Inc. Methods for isolating EG III cellulase component and EG III cellulase in polyethylene glycol using inorganic salt and polyethylene glycol
US6284874B1 (en) 1994-06-17 2001-09-04 Alpha Therapeutic Corporation Process for separating α1-proteinase inhibitor from cohn fraction IV1 and IV4 paste
US5616693A (en) * 1996-07-01 1997-04-01 Alpha Therapeutic Corporation Process for seperating alpha-1-proteinase inhibitor from COHN IV1 +1V4 paste
GB2318732A (en) 1996-11-01 1998-05-06 Johnson & Johnson Medical Wound healing compositions containing alpha-1-antitrypsin
AT407114B (de) * 1997-06-10 2000-12-27 Immuno Ag Alpha 1-antitrypsin-präparation sowie verfahren zu deren herstellung
US6093804A (en) * 1998-09-24 2000-07-25 American National Red Cross Method for purification of alpha-1 proteinase inhibitor
US6462180B1 (en) * 1999-11-24 2002-10-08 Bayer Corporation Method of preparing α-1 proteinase inhibitor
AU2001245240A1 (en) 2000-12-14 2002-06-24 Talecris Biotherapeutics, Inc. Method of preparing alpha-1 proteinase inhibitor
US7777006B2 (en) 2002-12-31 2010-08-17 Csl Behring L.L.C. Method for purification of alpha-1-antitrypsin
DK1664123T4 (da) * 2003-09-22 2012-03-05 Kamada Ltd Storskalafremstilling af alfa-1-proteinaseinhibitor og anvendelse deraf
GB0524432D0 (en) * 2005-11-30 2006-01-11 Nhs Blood & Transplant Method
WO2011150284A2 (en) 2010-05-26 2011-12-01 Baxter International Inc. Removal of serine proteases by treatment with finely divided silicon dioxide
AU2010202125B1 (en) 2010-05-26 2010-09-02 Takeda Pharmaceutical Company Limited A method to produce an immunoglobulin preparation with improved yield
US9902753B2 (en) 2012-06-05 2018-02-27 Cj Healthcare Corporation Method of purifying a long-acting human growth hormone

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ180199A (en) * 1976-03-04 1978-11-13 New Zealand Dev Finance Method of testing for the presence of elevated plasma liprotein concentration
US4110077A (en) * 1976-10-08 1978-08-29 Hoffmann-La Roche Inc. Determination of β-lipoproteins in blood serum with polyanethole sulfonate
EP0035204B2 (de) * 1980-03-05 1991-05-22 Miles Inc. Pasteurisierte therapeutisch aktive Proteinzusammensetzungen
EP0067293B1 (de) * 1981-05-01 1986-06-25 Medical Research Institute of San Francisco Verfahren zur Isolierung von Alpha-1-antitrypsin
US4379087A (en) * 1982-06-17 1983-04-05 Cutter Laboratories, Inc. Method of preparing alpha-1-proteinase inhibitor
JPS59128335A (ja) * 1983-01-12 1984-07-24 Fujirebio Inc α↓１−アンチトリプシンの分離取得方法

Also Published As

Publication number Publication date
EP0097274A3 (en) 1986-08-06
EP0097274A2 (de) 1984-01-04
EP0097274B1 (de) 1990-01-03
US4439358A (en) 1984-03-27

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Legal Events

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8364 No opposition during term of opposition