DE3366683D1 - Perfluoro-1-azatricyclic amine compound - Google Patents

Perfluoro-1-azatricyclic amine compound

Info

Publication number
DE3366683D1
DE3366683D1 DE8383303509T DE3366683T DE3366683D1 DE 3366683 D1 DE3366683 D1 DE 3366683D1 DE 8383303509 T DE8383303509 T DE 8383303509T DE 3366683 T DE3366683 T DE 3366683T DE 3366683 D1 DE3366683 D1 DE 3366683D1
Authority
DE
Germany
Prior art keywords
perfluoro
amine compound
azatricyclic
azatricyclic amine
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8383303509T
Other languages
English (en)
Inventor
Kazumasa Yokoyama
Chikara Fukaya
Yoshio Tsuda
Taizo Ono
Yoshio Arakawa
Yoshihisa Inoue
Youichiro Naito
Tadakazu Suyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
Original Assignee
Green Cross Corp Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP13766582A external-priority patent/JPS5927889A/ja
Priority claimed from JP13766382A external-priority patent/JPS5927893A/ja
Priority claimed from JP13766482A external-priority patent/JPS5927888A/ja
Application filed by Green Cross Corp Japan filed Critical Green Cross Corp Japan
Application granted granted Critical
Publication of DE3366683D1 publication Critical patent/DE3366683D1/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/20—Processes
    • C25B3/27—Halogenation
    • C25B3/28—Fluorination

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Materials Engineering (AREA)
  • Metallurgy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
DE8383303509T 1982-08-07 1983-06-17 Perfluoro-1-azatricyclic amine compound Expired DE3366683D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP13766582A JPS5927889A (ja) 1982-08-07 1982-08-07 パ−フルオロ三員環アミン化合物
JP13766382A JPS5927893A (ja) 1982-08-07 1982-08-07 パ−フルオロ三員環アミン化合物
JP13766482A JPS5927888A (ja) 1982-08-07 1982-08-07 パ−フルオロ三員環アミン化合物

Publications (1)

Publication Number Publication Date
DE3366683D1 true DE3366683D1 (de) 1986-11-13

Family

ID=27317504

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383303509T Expired DE3366683D1 (de) 1982-08-07 1983-06-17 Perfluoro-1-azatricyclic amine compound

Country Status (4)

Country Link
US (5) US4542147A (de)
EP (1) EP0103358B1 (de)
CA (1) CA1219258A (de)
DE (1) DE3366683D1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4865836A (en) * 1986-01-14 1989-09-12 Fluoromed Pharmaceutical, Inc. Brominated perfluorocarbon emulsions for internal animal use for contrast enhancement and oxygen transport
US4987154A (en) * 1986-01-14 1991-01-22 Alliance Pharmaceutical Corp. Biocompatible, stable and concentrated fluorocarbon emulsions for contrast enhancement and oxygen transport in internal animal use
US5684050A (en) * 1986-01-24 1997-11-04 Hemagen/Pfc Stable emulsions of highly fluorinated organic compounds
US5514720A (en) * 1986-07-09 1996-05-07 Hemagen/Pfc Stable emulsions of highly fluorinated organic compounds
US5243044A (en) * 1986-08-25 1993-09-07 International Therapeutics, Inc. Compounds of perfluoro[3,3,3]propellene and perfluoro hexamethylenetetramine
US5171755A (en) * 1988-04-29 1992-12-15 Hemagen/Pfc Emulsions of highly fluorinated organic compounds
US5403575A (en) * 1991-12-12 1995-04-04 Hemagen/Pfc Highly fluorinated, chloro-substituted organic compound-containing emulsions and methods of using them
US5614170A (en) * 1994-11-30 1997-03-25 Hemagen/Pfc Paramagnetic complexes of N-alkyl-N-hydroxylamides of organic acids and emulsions containing same for magnetic resonance imaging (MRI)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5331209B2 (de) * 1973-10-05 1978-09-01
US4105798A (en) * 1976-07-19 1978-08-08 Sun Ventures, Inc. Perfluoro polycyclic compounds for use as synthetic blood and perfusion media
US4186253A (en) * 1978-10-10 1980-01-29 The Green Cross Corporation Perfusate for preserving organ to be transplanted and preserving method
US4252827A (en) * 1979-05-23 1981-02-24 The Green Cross Corporation Oxygen-transferable fluorocarbon emulsion
CA1187882A (en) * 1981-11-27 1985-05-28 Kazumasa Yokoyama Perfluoro compound and emulsion thereof
JPS5892680A (ja) * 1981-11-27 1983-06-02 Green Cross Corp:The パ−フルオロビシクロ化合物
JPS58170782A (ja) * 1982-01-22 1983-10-07 アイ・エス・シ−・ケミカルズ・リミテツド 過弗素化複素環式化合物およびこれを含むエマルシヨン
US4530926A (en) * 1982-06-29 1985-07-23 The Green Cross Corporation Perfluorotricyclic amines as oxygen carriers
JPS5946218A (ja) * 1982-09-09 1984-03-15 Green Cross Corp:The フルオロカ−ボン乳化製剤
US4535085A (en) * 1983-03-29 1985-08-13 The Green Cross Corporation Perfluorotricyclic amines as oxygen carriers

Also Published As

Publication number Publication date
US4613605A (en) 1986-09-23
EP0103358A1 (de) 1984-03-21
US4542147A (en) 1985-09-17
CA1219258A (en) 1987-03-17
US4605650A (en) 1986-08-12
EP0103358B1 (de) 1986-10-08
US4604385A (en) 1986-08-05
US4654337A (en) 1987-03-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee