DE330629T1 - Guanidin-derivate mit hypotensiver wirkung, diese enthaltende zusammensetzungen und verfahren zu deren herstellung. - Google Patents

Guanidin-derivate mit hypotensiver wirkung, diese enthaltende zusammensetzungen und verfahren zu deren herstellung.

Info

Publication number: DE330629T1
Authority: DE; Germany
Prior art keywords: production; same; compositions containing; guanidine derivatives; hypotensive effect
Prior art date: 1988-02-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

DE198989830067T

Other languages

English (en)

Inventor

Giuliano I-00136 Rome It Delle Monache

Franco I-00167 Rome It Delle Monache

Bruno I-00066 Manziana-Rome It Botta

Stella Montevideo Uy Bonnevaux Castillo

Romulo Valencia Ve Espinal

Carlo Bracciano-Rome It De Luca

Marco I-52028 Terranuova Bracciolini Carmignani (Ar), It

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Consiglio Nazionale delle Richerche CNR

Original Assignee

Consiglio Nazionale delle Richerche CNR

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-02-24

Filing date

1989-02-17

Publication date

1990-04-12

1989-02-17 Application filed by Consiglio Nazionale delle Richerche CNR filed Critical Consiglio Nazionale delle Richerche CNR

1990-04-12 Publication of DE330629T1 publication Critical patent/DE330629T1/de

Status Pending legal-status Critical Current

Links

ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical class NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 title 1
229940083094 guanine derivative acting on arteriolar smooth muscle Drugs 0.000 title 1
230000001077 hypotensive effect Effects 0.000 title 1
239000000203 mixture Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Plant Substances (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DE198989830067T 1988-02-24 1989-02-17 Guanidin-derivate mit hypotensiver wirkung, diese enthaltende zusammensetzungen und verfahren zu deren herstellung. Pending DE330629T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT47665/88A IT1219846B (it)	1988-02-24	1988-02-24	Nuovi derivati guandinici ad attivita' ipotensia,composizione che li contengono e relativo procedimento di estrazione e purificazione da materiale botanico

Publications (1)

Publication Number	Publication Date
DE330629T1 true DE330629T1 (de)	1990-04-12

Family

ID=11261768

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE198989830067T Pending DE330629T1 (de)	1988-02-24	1989-02-17	Guanidin-derivate mit hypotensiver wirkung, diese enthaltende zusammensetzungen und verfahren zu deren herstellung.

Country Status (7)

Country	Link
US (1)	US5059624A (de)
EP (1)	EP0330629A3 (de)
JP (1)	JPH023661A (de)
DE (1)	DE330629T1 (de)
ES (1)	ES2013585A4 (de)
GR (1)	GR900300066T1 (de)
IT (1)	IT1219846B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5344846A (en) *	1992-12-30	1994-09-06	The United States Of America As Represented By The Department Of Health And Human Services	Compositions and methods for inhibiting deoxyhypusine synthase and the growth of cells
US5424447A (en) *	1993-07-07	1995-06-13	The Medical College Of Wisconsin Research Foundation, Inc.	Heme binding compounds and use thereof
ATE195933T1 (de) *	1994-03-10	2000-09-15	Searle & Co	L-n6-(1-iminoethyl)lysin - derivate und ihre verwendung als no-synthase - inhibitoren
US5514675A (en) *	1994-10-20	1996-05-07	Eli Lilly And Company	Naphthyl bradykinin receptor antagonists
GB9511757D0 (en) *	1995-05-19	1995-08-02	Univ Strathclyde	Agents for reducing weight
US5574059A (en) *	1995-10-27	1996-11-12	Cornell Research Foundation, Inc.	Treating disorders mediated by vascular smooth muscle cell proliferation
FR2802769B1 (fr) *	1999-12-23	2004-01-16	Oreal	Extrait de vegetal du genre leontopodium et compositions le contenant
JP2001199884A (ja) *	2000-01-21	2001-07-24	Seiwa Yakuhin Kk	鎮痛作用剤
JP2002363075A (ja) *	2001-06-05	2002-12-18	Kao Corp	高血圧症予防・治療剤
TW200403215A (en) *	2002-07-04	2004-03-01	Ajinomoto Kk	Ultraviolet-absorbing composition
ITRM20020625A1 (it) *	2002-12-17	2004-06-18	Sigma Tau Ind Farmaceuti	Derivati di guanidine variamente sostituite, loro uso come medicamenti ad attivita' antidiabetica e/o antiobesita'.
DE102008061247A1 (de) *	2008-12-10	2010-06-24	Christian-Albrechts-Universität Zu Kiel	Inhibitoren der Dimethylarginin Dimethylaminohydrolase

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE625179A (de) *
US2734904A (en) *		1956-02-14		Xcxnhxc-nh
FR78162E (fr) *	1960-06-09	1962-06-15	Ciba Geigy	Procédé de préparation de nouvelles alcoylène-imino-alcoyl-guanidines, de leurs sels et composés d'ammonium quaternaires
US3201459A (en) *	1961-11-23	1965-08-17	Farmaceutici Italia	Guanidine
CH433246A (de) *	1962-06-25	1967-04-15	Ciba Geigy	Verfahren zur Herstellung von Guanidinverbindungen
SE321464B (de) *	1962-08-23	1970-03-09	Pharmacia Ab
US3202710A (en) *	1962-12-06	1965-08-24	Rexall Drug Chemical	1-(2-cycloalkyl-2-dilower alkylamino-ethyl) guanidines
US3459792A (en) *	1965-09-27	1969-08-05	Ciba Geigy Corp	Cinnamyloxy guanidines and the salts thereof
US3475459A (en) *	1966-11-23	1969-10-28	Canadian Patents Dev	Hordatine compounds and synthesis
HU178398B (en) *	1979-06-12	1982-04-28	Gyogyszerkutato Intezet	Process for producing new agmatine derivatives of activity against haemagglutination
US4814007A (en) *	1986-01-16	1989-03-21	Henkel Corporation	Recovery of precious metals
US4851441A (en) *	1986-06-26	1989-07-25	Harbor Branch Oceanographic Institution, Inc.	Antiviral guanidine derivatives compositions and their methods of use

1988
- 1988-02-24 IT IT47665/88A patent/IT1219846B/it active
1989
- 1989-02-17 DE DE198989830067T patent/DE330629T1/de active Pending
- 1989-02-17 EP EP19890830067 patent/EP0330629A3/de not_active Withdrawn
- 1989-02-17 ES ES89830067T patent/ES2013585A4/es active Pending
- 1989-02-23 JP JP1045003A patent/JPH023661A/ja active Pending
- 1989-02-24 US US07/315,107 patent/US5059624A/en not_active Expired - Fee Related
1991
- 1991-07-31 GR GR90300066T patent/GR900300066T1/el unknown

Also Published As

Publication number	Publication date
EP0330629A3 (de)	1990-10-31
IT1219846B (it)	1990-05-24
IT8847665A0 (it)	1988-02-24
US5059624A (en)	1991-10-22
EP0330629A2 (de)	1989-08-30
GR900300066T1 (en)	1991-07-31
JPH023661A (ja)	1990-01-09
ES2013585A4 (es)	1990-05-16

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