DE3279470D1 - New cephem compounds, processes for their preparation, pharmaceutical compositions containing them and their starting compounds - Google Patents

New cephem compounds, processes for their preparation, pharmaceutical compositions containing them and their starting compounds

Info

Publication number
DE3279470D1
DE3279470D1 DE8282102818T DE3279470T DE3279470D1 DE 3279470 D1 DE3279470 D1 DE 3279470D1 DE 8282102818 T DE8282102818 T DE 8282102818T DE 3279470 T DE3279470 T DE 3279470T DE 3279470 D1 DE3279470 D1 DE 3279470D1
Authority
DE
Germany
Prior art keywords
compounds
processes
preparation
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282102818T
Other languages
English (en)
Inventor
Tsutomu Teraji
Kazuo Sakane
Jiro Goto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE3279470D1 publication Critical patent/DE3279470D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8282102818T 1981-04-03 1982-04-02 New cephem compounds, processes for their preparation, pharmaceutical compositions containing them and their starting compounds Expired DE3279470D1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB8110556 1981-04-03
GB8122896 1981-07-24
GB8132775 1981-10-30

Publications (1)

Publication Number Publication Date
DE3279470D1 true DE3279470D1 (en) 1989-04-06

Family

ID=27261154

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282102818T Expired DE3279470D1 (en) 1981-04-03 1982-04-02 New cephem compounds, processes for their preparation, pharmaceutical compositions containing them and their starting compounds

Country Status (4)

Country Link
EP (1) EP0062321B1 (de)
JP (1) JPH02218685A (de)
DE (1) DE3279470D1 (de)
ES (1) ES511101A0 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3248281A1 (de) * 1982-12-28 1984-06-28 Hoechst Ag, 6230 Frankfurt Kristalisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung
GB8401093D0 (en) * 1984-01-16 1984-02-15 Fujisawa Pharmaceutical Co Cephem compounds
NO165842C (no) * 1984-04-23 1991-04-17 Takeda Chemical Industries Ltd Analogifremgangsmaate for fremstilling av terapeutisk aktive cefem-forbindelser.
US4788185A (en) * 1984-04-23 1988-11-29 Takeda Chemical Industries, Ltd. Cephalosporin compounds
JPS60231683A (ja) * 1984-05-02 1985-11-18 Teijin Ltd セフアロスポリン誘導体その製造法及びそれを有効成分とする抗菌剤
PH22107A (en) * 1984-06-07 1988-06-01 Takeda Chemical Industries Ltd 3-pyrazolo(1,5-a)pyrdinium cephem compounds
IL77458A (en) * 1985-01-14 1990-07-26 Eisai Co Ltd Cephem derivatives,their production and antibacterial compositions containing them and certain novel intermediates therefor
US4698336A (en) * 1985-01-30 1987-10-06 Eisai Co., Ltd. 3-(pyrrolidinio)methyl-3-cephem derivatives
EP0203271B1 (de) * 1985-03-01 1993-05-26 Takeda Chemical Industries, Ltd. Antibakterielle Verbindungen, ihre Herstellung und Verwendung
ATE89826T1 (de) * 1985-03-01 1993-06-15 Takeda Chemical Industries Ltd Antibakterielle verbindungen, ihre herstellung und verwendung.
ATE82976T1 (de) * 1985-09-03 1992-12-15 Otsuka Kagaku Kk Cephalosporinderivate.
US4826834A (en) * 1985-09-27 1989-05-02 Takeda Chemical Industries, Ltd. Cephem compounds
CN86107947A (zh) 1985-11-22 1987-05-27 藤沢药品工业株式会社 新的头孢烯化合物及其制备方法
CA1293719C (en) * 1986-09-22 1991-12-31 Takao Takaya Cephem compounds and processes for preparation thereof
GB8721016D0 (en) * 1987-09-07 1987-10-14 Fujisawa Pharmaceutical Co Cephem compounds
US5210080A (en) * 1987-09-07 1993-05-11 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
IE63094B1 (en) * 1987-09-14 1995-03-22 Fujisawa Pharmaceutical Co Cephem compound and a process for preparation thereof
GB8805642D0 (en) * 1988-03-09 1988-04-07 Fujisawa Pharmaceutical Co New cephem compounds & processes for preparation thereof
US5173485A (en) * 1988-03-09 1992-12-22 Fujisawa Pharmaceutical Company, Ltd. Cephem compounds
US5202315A (en) * 1989-05-11 1993-04-13 Lucky, Ltd. Cephalosporin compounds
US5215982A (en) * 1989-11-10 1993-06-01 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US5194433A (en) * 1990-11-13 1993-03-16 Bristol-Myers Squibb Company Antibiotic c-3 catechol-substituted cephalosporin compounds, compositions and method of use thereof
KR930009796B1 (ko) * 1991-05-25 1993-10-11 주식회사 대웅제약 신규의 세팔로스포린 및 그의 제조방법
KR0157073B1 (ko) * 1992-10-01 1998-11-16 김태훈 세팔로스포린 유도체 및 그의 제조방법
US5654005A (en) * 1995-06-07 1997-08-05 Andrx Pharmaceuticals, Inc. Controlled release formulation having a preformed passageway
TW526202B (en) 1998-11-27 2003-04-01 Shionogi & Amp Co Broad spectrum cephem having benzo[4,5-b]pyridium methyl group of antibiotic activity
US7192943B2 (en) 2003-09-18 2007-03-20 Astellas Pharma Inc. Cephem compounds

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4970990A (de) * 1973-09-29 1974-07-09
ES485440A1 (es) * 1978-10-27 1980-07-01 Glaxo Group Ltd Un procedimiento para la preparacion de antibioticos de ce- falosporina
AU529338B2 (en) * 1978-10-27 1983-06-02 Glaxo Group Limited Cephalosporin compounds
NL7908318A (nl) * 1978-11-15 1980-05-19 Glaxo Group Ltd Nieuwe verbindingen met antibiotische eigenschappen, werkwijze voor de bereiding daarvan, alsmede farmaceutische preparaten die deze bevatten.
IT1207006B (it) * 1978-11-15 1989-05-17 Glaxo Group Ltd Antibiotici cefalosporinici composizioni che li contengono e procedimento per produrli
JPS55105689A (en) * 1978-12-29 1980-08-13 Fujisawa Pharmaceut Co Ltd Novel cephem and cepham compounds, their preparation and preventive and remedy for microbism
BE881870A (fr) * 1979-02-23 1980-08-22 Glaxo Group Ltd Nouvelles cephalosporines qui exercent une activite contre des organismes gram-negatifs
NZ192943A (en) * 1979-02-23 1982-12-21 Glaxo Group Ltd Cephalosporin antibiotics
EP0025017A1 (de) * 1979-08-28 1981-03-11 Ciba-Geigy Ag Polyazathiaverbindungen, Verfahren zu ihrer Herstellung, pharmazeutische Präparate enthaltend solche Verbindungen und Verwendung von letzteren
GR78245B (de) * 1980-09-12 1984-09-26 Ciba Geigy Ag
ZA816321B (en) * 1980-09-12 1982-09-29 Ciba Geigy Ammoniomethyl compounds,processes for their manufacture,pharmaceutical preparations that contain these compounds,and the use of these compounds
JPS584789A (ja) * 1981-04-03 1983-01-11 Fujisawa Pharmaceut Co Ltd 新規セフエム化合物およびその製造法
US4401668A (en) * 1981-10-02 1983-08-30 Eli Lilly And Company Pyrazinium substituted cephalosporins

Also Published As

Publication number Publication date
EP0062321B1 (de) 1989-03-01
JPH02218685A (ja) 1990-08-31
ES8306160A1 (es) 1983-05-01
EP0062321A2 (de) 1982-10-13
EP0062321A3 (en) 1983-11-09
ES511101A0 (es) 1983-05-01
JPH0524159B2 (de) 1993-04-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee