DE3273982D1 - Compounds having antitumour activity - Google Patents

Compounds having antitumour activity

Info

Publication number
DE3273982D1
DE3273982D1 DE8282304420T DE3273982T DE3273982D1 DE 3273982 D1 DE3273982 D1 DE 3273982D1 DE 8282304420 T DE8282304420 T DE 8282304420T DE 3273982 T DE3273982 T DE 3273982T DE 3273982 D1 DE3273982 D1 DE 3273982D1
Authority
DE
Germany
Prior art keywords
compounds
antitumour activity
antitumour
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282304420T
Other languages
German (de)
Inventor
Gordon William Rewcastle
Graham John Atwell
Bruce Charles Baguley
William Alexander Denny
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Application granted granted Critical
Publication of DE3273982D1 publication Critical patent/DE3273982D1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/64—Acridine or hydrogenated acridine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/06—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C07F9/2454—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/247—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic of aromatic amines (N-C aromatic linkage)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8282304420T 1981-08-21 1982-08-20 Compounds having antitumour activity Expired DE3273982D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NZ198115A NZ198115A (en) 1981-08-21 1981-08-21 9-anilinoacridines;pharmaceutical compositions

Publications (1)

Publication Number Publication Date
DE3273982D1 true DE3273982D1 (en) 1986-12-04

Family

ID=19919716

Family Applications (2)

Application Number Title Priority Date Filing Date
DE8282304420T Expired DE3273982D1 (en) 1981-08-21 1982-08-20 Compounds having antitumour activity
DE198282304420T Pending DE73155T1 (en) 1981-08-21 1982-08-20 ANTITUARY ACTIVITIES.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE198282304420T Pending DE73155T1 (en) 1981-08-21 1982-08-20 ANTITUARY ACTIVITIES.

Country Status (5)

Country Link
US (2) US4479000A (en)
EP (1) EP0073155B1 (en)
JP (1) JPS5843987A (en)
DE (2) DE3273982D1 (en)
NZ (1) NZ198115A (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ200715A (en) * 1982-05-24 1986-06-11 New Zealand Dev Finance Acridine derivatives and pharmaceutical compositions containing such
NZ201084A (en) * 1982-06-25 1985-10-11 New Zealand Dev Finance 4-carboxamidoacridine derivatives and pharmaceutical compositions containing such
EP0338372A3 (en) * 1988-04-22 1991-10-09 American Cyanamid Company Solubilized pro-drugs
AU7579991A (en) * 1990-02-20 1991-09-18 Gilead Sciences, Inc. Pseudonucleosides and pseudonucleotides and their polymers
CZ283038B6 (en) * 1991-01-11 1997-12-17 Laboratoires Glaxo Sa Acridine derivatives, process of their preparation and pharmaceutical preparations in which they are comprised
SG169238A1 (en) * 2004-08-11 2011-03-30 Williamsburg Holdings Llc Noncardiotoxic pharmaceutical compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE575273A (en) * 1958-02-01
US4258191A (en) * 1979-03-29 1981-03-24 The United States Of America As Represented By The Secretary Of Health, Education And Welfare Multi-step process for the production of methanesulfon-m-anisidide, 4'-(9-acridinylamino)-
AU534608B2 (en) * 1979-09-14 1984-02-09 Warner-Lambert Corporation Compounds having antitumour properties

Also Published As

Publication number Publication date
US4479000A (en) 1984-10-23
EP0073155A2 (en) 1983-03-02
EP0073155B1 (en) 1986-10-29
NZ198115A (en) 1985-05-31
EP0073155A3 (en) 1983-05-11
JPS5843987A (en) 1983-03-14
US4537729A (en) 1985-08-27
JPH0132230B2 (en) 1989-06-29
DE73155T1 (en) 1985-02-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee