DE3070768D1 - 1-((substituted-naphthyl)ethyl)-imidazole derivatives, pharmaceutical compositions containing them and methods of making them - Google Patents
1-((substituted-naphthyl)ethyl)-imidazole derivatives, pharmaceutical compositions containing them and methods of making themInfo
- Publication number
- DE3070768D1 DE3070768D1 DE8080300680T DE3070768T DE3070768D1 DE 3070768 D1 DE3070768 D1 DE 3070768D1 DE 8080300680 T DE8080300680 T DE 8080300680T DE 3070768 T DE3070768 T DE 3070768T DE 3070768 D1 DE3070768 D1 DE 3070768D1
- Authority
- DE
- Germany
- Prior art keywords
- naphthyl
- ethyl
- substituted
- making
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/019,202 US4277486A (en) | 1979-03-09 | 1979-03-09 | 1-[(Substituted-naphthyl)ethyl]-imidazole derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3070768D1 true DE3070768D1 (en) | 1985-07-25 |
Family
ID=21791965
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8080300680T Expired DE3070768D1 (en) | 1979-03-09 | 1980-03-06 | 1-((substituted-naphthyl)ethyl)-imidazole derivatives, pharmaceutical compositions containing them and methods of making them |
Country Status (7)
Country | Link |
---|---|
US (1) | US4277486A (de) |
EP (1) | EP0016587B1 (de) |
JP (1) | JPS55122767A (de) |
AT (1) | ATE13882T1 (de) |
CA (1) | CA1153000A (de) |
DE (1) | DE3070768D1 (de) |
ES (1) | ES489353A0 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0092158A3 (de) * | 1982-04-21 | 1985-11-27 | Mitsubishi Kasei Corporation | Thiazolidinderivate und fungizide Zusammensetzungen die sie enthalten |
US4489087A (en) * | 1982-10-13 | 1984-12-18 | Syntex (U.S.A.) Inc. | Spermicidal thioketal substituted N-alkyl imidazoles |
US4590063A (en) * | 1983-06-24 | 1986-05-20 | Adria Laboratories, Inc. | Anticonvulsants |
US4540814A (en) * | 1983-06-24 | 1985-09-10 | Adria Laboratories, Inc. | 1,4-Dimethoxy naphthalenecarboxamide anticonvulsants |
US4870094A (en) * | 1984-05-02 | 1989-09-26 | Uniroyal Chemical Company, Inc. | Substituted imidazoles and triazoles |
JPH03115267A (ja) * | 1989-09-28 | 1991-05-16 | Maruho Kk | プロピオフエノン誘導体、その製造方法、それを含む中枢性筋弛緩剤および抗痙攣剤 |
GB9125791D0 (en) * | 1991-12-04 | 1992-02-05 | Schering Agrochemicals Ltd | Herbicides |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3936470A (en) * | 1975-01-27 | 1976-02-03 | Janssen Pharmaceutica N.V. | 1,3-Dioxolan-2-ylmethylimidazoles |
CA1065873A (en) * | 1975-01-27 | 1979-11-06 | Janssen Pharmaceutica Naamloze Vennootschap | Imidazole derivatives |
US4085209A (en) * | 1975-02-05 | 1978-04-18 | Rohm And Haas Company | Preparation and safening effect of 1-substituted imidazole metal salt complexes |
US4172141A (en) * | 1976-03-17 | 1979-10-23 | Syntex (U.S.A.) Inc. | N-(naphthylethyl)imidazole derivatives |
US4141908A (en) * | 1976-10-15 | 1979-02-27 | Janssen Pharmaceutica N.V. | 2-Aryl-1,3-dioxolanes |
US4150153A (en) * | 1977-05-13 | 1979-04-17 | Syntex (U.S.A.) Inc. | 1-(Naphthylethyl)imidazole derivatives |
US4413003A (en) * | 1977-07-29 | 1983-11-01 | Rohm And Haas Company | β-Hydroxyarylethylimidazoles |
IT1160898B (it) * | 1977-11-04 | 1987-03-11 | Syntex Inc | Derivati dell'1-(naftiletil)-imidazolo,particolarmente utili come anticonvulsivi ed antisecretivi,e procedimento per la loro preparazione |
FR2409990A1 (fr) * | 1977-11-25 | 1979-06-22 | Syntex Inc | Derives de 1-(naphtylethyl)imidazoles et application a titre de medicament |
US4246274A (en) * | 1978-05-10 | 1981-01-20 | Bayer Aktiengesellschaft | Antimycotic hydroxypropyl-imidazoles |
IT1097314B (it) * | 1978-07-26 | 1985-08-31 | Recordati Chem Pharm | Derivati dell'imidazolo ad attivita' anticonvulsivante |
-
1979
- 1979-03-09 US US06/019,202 patent/US4277486A/en not_active Expired - Lifetime
-
1980
- 1980-03-04 CA CA000346988A patent/CA1153000A/en not_active Expired
- 1980-03-06 AT AT80300680T patent/ATE13882T1/de active
- 1980-03-06 DE DE8080300680T patent/DE3070768D1/de not_active Expired
- 1980-03-06 EP EP80300680A patent/EP0016587B1/de not_active Expired
- 1980-03-08 ES ES489353A patent/ES489353A0/es active Granted
- 1980-03-10 JP JP3021080A patent/JPS55122767A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0016587B1 (de) | 1985-06-19 |
US4277486A (en) | 1981-07-07 |
ATE13882T1 (de) | 1985-07-15 |
JPS55122767A (en) | 1980-09-20 |
ES8104241A1 (es) | 1981-04-16 |
CA1153000A (en) | 1983-08-30 |
EP0016587A1 (de) | 1980-10-01 |
ES489353A0 (es) | 1981-04-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8339 | Ceased/non-payment of the annual fee |