DE3062310D1 - Pyrimidone derivatives, processes for their preparation and pharmaceutical compositions containing them - Google Patents

Pyrimidone derivatives, processes for their preparation and pharmaceutical compositions containing them

Info

Publication number
DE3062310D1
DE3062310D1 DE8080300478T DE3062310T DE3062310D1 DE 3062310 D1 DE3062310 D1 DE 3062310D1 DE 8080300478 T DE8080300478 T DE 8080300478T DE 3062310 T DE3062310 T DE 3062310T DE 3062310 D1 DE3062310 D1 DE 3062310D1
Authority
DE
Germany
Prior art keywords
processes
preparation
pharmaceutical compositions
compositions containing
pyrimidone derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8080300478T
Other languages
English (en)
Inventor
Thomas Henry Brown
Graham John Durant
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith Kline and French Laboratories Ltd
Original Assignee
Smith Kline and French Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline and French Laboratories Ltd filed Critical Smith Kline and French Laboratories Ltd
Application granted granted Critical
Publication of DE3062310D1 publication Critical patent/DE3062310D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE8080300478T 1979-02-21 1980-02-20 Pyrimidone derivatives, processes for their preparation and pharmaceutical compositions containing them Expired DE3062310D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7906070 1979-02-21

Publications (1)

Publication Number Publication Date
DE3062310D1 true DE3062310D1 (en) 1983-04-21

Family

ID=10503327

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8080300478T Expired DE3062310D1 (en) 1979-02-21 1980-02-20 Pyrimidone derivatives, processes for their preparation and pharmaceutical compositions containing them

Country Status (18)

Country Link
US (1) US4521418A (de)
EP (1) EP0015138B1 (de)
JP (1) JPS55115883A (de)
AR (1) AR224392A1 (de)
AT (1) AT377260B (de)
AU (1) AU536194B2 (de)
DD (1) DD149217A5 (de)
DE (1) DE3062310D1 (de)
DK (1) DK74680A (de)
ES (1) ES488772A0 (de)
FI (1) FI800515A (de)
GR (1) GR74009B (de)
IE (1) IE49270B1 (de)
NO (1) NO800463L (de)
PL (1) PL222115A1 (de)
PT (1) PT70850A (de)
RO (1) RO79711A (de)
ZA (1) ZA801002B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4227271A (en) * 1979-08-09 1980-10-14 Kulka Thomas S Foot supporting strap for hospital bed
US4383343A (en) * 1979-08-09 1983-05-17 Kulka Thomas S Foot supporting strap for hospital bed
NZ202797A (en) * 1981-12-28 1985-08-30 Lilly Co Eli Pyrimidine derivatives and pharmaceutical compositions
CA1211111A (en) * 1982-02-15 1986-09-09 Isao Yanagisawa Process for preparing novel pyrimidone compounds
US4808589A (en) * 1982-02-20 1989-02-28 Smith Kline & French Laboratories Limited Pyrimidone derivatives
US4444381A (en) * 1982-05-11 1984-04-24 Wayne Sherwyn J Operating table accessory, particularly for lumbar laminectomies
DE3220118A1 (de) * 1982-05-28 1983-12-01 Bayer Ag, 5090 Leverkusen Alkylenverbrueckte guanidinothiazolderivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE3306102C1 (de) * 1983-02-22 1984-08-02 Ludwig Heumann & Co GmbH, 8500 Nürnberg Pyridin-Pyrimidinon-Derivate,Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
GB8320505D0 (en) * 1983-07-29 1983-09-01 Smith Kline French Lab Chemical compounds
US4772704A (en) * 1983-09-21 1988-09-20 Bristol-Myers Company 2,5-disubstituted-4(3H)-pyrimidones having histamine H2 -receptor antagonist activity
GB8421427D0 (en) * 1984-08-23 1984-09-26 Smith Kline French Lab Chemical compounds
IT1178026B (it) * 1984-10-05 1987-09-03 Medosan Ind Biochimi Derivati del 2-amino-tiazolo
JO1410B1 (en) * 1984-11-03 1986-11-30 سميث كلاين اند فرينش لابوراتوريز ليمتد Vehicles
JP2807577B2 (ja) * 1990-06-15 1998-10-08 エーザイ株式会社 環状アミド誘導体
US5611097A (en) * 1995-08-17 1997-03-18 Dumke; Dan Foot stop for beds
EP4196793A1 (de) 2020-08-11 2023-06-21 Université de Strasbourg Auf lebermakrophagen abzielende h2-blocker zur prävention und behandlung von lebererkrankungen und krebs

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3980781A (en) * 1966-03-31 1976-09-14 Imperial Chemical Industries Limited Fungicidal composition and method containing 2-amino-pyrimidines
GB1223686A (en) * 1967-02-24 1971-03-03 Ici Ltd Salts of pyrimidine derivatives and the use thereof as fungicides
GB1419994A (en) * 1973-05-03 1976-01-07 Smith Kline French Lab Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them
IN146736B (de) * 1975-10-02 1979-08-25 Smith Kline French Lab
US4145546A (en) * 1975-10-02 1979-03-20 Smith Kline & French Laboratories Limited 4-Pyrimidone compounds
US4154834A (en) * 1975-12-29 1979-05-15 Smith Kline & French Laboratories Limited Substituted isocytosines having histamine H2 -antagonist activity
US4216318A (en) * 1975-12-29 1980-08-05 Smith Kline & French Laboratories Limited Heterocyclic alkyl 4-pyrimidones
MW5076A1 (en) * 1975-12-29 1978-02-08 Smith Kline French Lab Pharmacologicalle active compounds
IE47044B1 (en) * 1977-04-20 1983-12-14 Ici Ltd Guanidine derivatives
DE2817078C2 (de) * 1977-04-20 1995-06-14 Zeneca Ltd Guanidinderivate
US4165378A (en) * 1977-04-20 1979-08-21 Ici Americas Inc. Guanidine derivatives of imidazoles and thiazoles
DE2961923D1 (en) * 1978-01-18 1982-03-11 Ici Plc Antisecretory guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them
US4374836A (en) * 1978-10-16 1983-02-22 Imperial Chemical Industries Ltd. Antisecretory heterocyclic derivatives, process for their manufacture and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
EP0015138B1 (de) 1983-03-16
ES8103078A1 (es) 1981-02-16
AR224392A1 (es) 1981-11-30
NO800463L (no) 1980-08-22
PT70850A (en) 1980-03-01
FI800515A (fi) 1980-08-22
ATA98280A (de) 1984-07-15
IE800337L (en) 1980-08-21
PL222115A1 (de) 1980-12-01
AU536194B2 (en) 1984-04-19
GR74009B (de) 1984-06-06
ES488772A0 (es) 1981-02-16
AT377260B (de) 1985-02-25
AU5579180A (en) 1980-08-28
ZA801002B (en) 1981-03-25
US4521418A (en) 1985-06-04
RO79711A (ro) 1982-08-17
EP0015138A1 (de) 1980-09-03
DD149217A5 (de) 1981-07-01
IE49270B1 (en) 1985-09-04
DK74680A (da) 1980-08-22
JPS55115883A (en) 1980-09-06

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee