DE3046324A1 - Microbicide effective against microbes which affect the lungs - contains calcium hypochlorite and water which produce hypochlorous acid, which produces iso:hypochlorous acid which releases active oxygen - Google Patents
Microbicide effective against microbes which affect the lungs - contains calcium hypochlorite and water which produce hypochlorous acid, which produces iso:hypochlorous acid which releases active oxygenInfo
- Publication number
- DE3046324A1 DE3046324A1 DE19803046324 DE3046324A DE3046324A1 DE 3046324 A1 DE3046324 A1 DE 3046324A1 DE 19803046324 DE19803046324 DE 19803046324 DE 3046324 A DE3046324 A DE 3046324A DE 3046324 A1 DE3046324 A1 DE 3046324A1
- Authority
- DE
- Germany
- Prior art keywords
- hypochlorous acid
- lungs
- microbicide
- water
- calcium hypochlorite
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/20—Elemental chlorine; Inorganic compounds releasing chlorine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
"Verfahren zur Herstellung eines Präparates zur Vernichtung von Mikroben, welche die Lunge befallen" Die Erfindung betrifft ein Verfahren zur Herstellung eines Präparates zur Vernichtung von Mikroben, welche die Lunge befallen."Process for the production of a preparation for the destruction of microbes, affecting the lungs "The invention relates to a method of manufacture a preparation for killing microbes that attack the lungs.
Es handelt sich um ein weißes hygroskopisches Pulver mit schwachem Chlorgeruch. Physikalische und chemische Eigenschaften sind aus jedem chemischen Nachschlagewerk zu ersehen.It is a white, hygroscopic powder with a faint Chlorine smell. Physical and chemical properties are made up of every chemical Reference book to be seen.
Im fertigen Zustand wird dieses Präparat in der Textilindustrie und in anderen Bereichen als Bleichmittel verwendet.In the finished state, this preparation is used in the textile industry and used in other fields as bleach.
Die chemische Zusammensetzung des Präparates und der Funktionsmechanismus wen durch nachstehende Formeln erleutert.The chemical composition of the preparation and the mechanism of operation whom is explained by the following formulas.
Hypochloridum calcium Ca (OCl)2 -20Cl + OH unterchlorige Säure 1) Ril + HOC2> = ROH + HCi 2) RH + HOCl = H2O + RCl Die zwei Formeln 1) und 2) sind die Ergänzung für die obengenannte Formel. Das -R- lat in der Chemie die gleiche Bedeutung wie -X- in der Mathematik. Diese Formeln zeigen die chemische Reaktion von Oxydation und Reduktion mit unterchloriger Säure.Hypochloridum calcium Ca (OCl) 2 -20Cl + OH hypochlorous acid 1) Ril + HOC2> = ROH + HCi 2) RH + HOCl = H2O + RCl The two formulas 1) and 2) are the supplement to the above formula. The -R- has the same meaning in chemistry as -X- in mathematics. These formulas show the chemical reaction of oxidation and reduction with hypochlorous acid.
Bei einem PH-Wert von ca. 7 ist in der Lösung isounterchlorige Säure a) Elektronen-Konfiguration b) Strukturformel unterchlorige Säure Iso-unterchlorige Säure bildet die Tendenz zur Ausscheidung eines aktiven Sauerstoffatoms, das einen Dakteriiciden Effekt aufwcist. At a pH value of approx. 7 is in the solution iso-chlorous acid a) Electron configuration b) structural formula Hypochlorous acid Iso-hypochlorous acid tends to excrete an active oxygen atom, which has a bacteriicidal effect.
Iso-unterchiorige Säure Pharmakologische Eigenschaften: Wie aus vorstehendem ersichtlich, hat das aktivierte Sauerstoffatom bei Berührung mit biologischen Umgebungen eine starke osydierende Wirkung mit ausgebildetem bakteriicidem Effekt auf die meisten grampositiven Mikroben und auf die anaerobe Flora. Dieses Präparat ist ein starkes antibakterielles Mittel, und führt nicht zur Gewöhnung der Mikroben und auch nicht zu allergetischen Erscheinungen. Die klinische Anwendung ist eine zweifach gefilterte 0,2 %-ige wässrige Lösung in einer Mertge von 20 bis 50 ml intravenös gespritzt. Nach der Injektion muß die Vene mit einer physiologischen Lösung gespült werden, um eine Venenentzündung zu vermeiden. Eine Therapie besteht aus 15 bis "O Injektionen.Iso-subchiorous acid Pharmacological properties: As from above As can be seen, the activated oxygen atom has when in contact with biological environments a strong oxidizing effect with an established bacteriicidal effect on most of them gram positive microbes and anaerobic flora. This supplement is a strong one antibacterial agent, and does not lead to the habituation of the microbes either to allergic phenomena. The clinical application is filtered twice 0.2% aqueous solution in a Mertge of 20 to 50 ml injected intravenously. After the injection, the vein must be flushed with a physiological solution, to avoid phlebitis. One therapy consists of 15 to "O injections.
Das Präparat zerfällt bei der Verarbeitung im Organismus bis zu den Endprodukten, die aus der Formel ersichtlich sind.The preparation disintegrates during processing in the organism up to the End products that can be seen from the formula.
Die Anwendung des Präparates erfolgt bei chronischen Leiden, eitrigen Prozesse der Lunge, chronischer Lungenentzündung, Bronchoektasie, chronischen Lungenabszessen, Lungenbrand. Die Erfolgsquote lag bei Versuchen stets höher, als der Heileffekt bei der Anwendung von Antibiotika. Besonders aktuell ist die Anwendung dieses Präparates bei Patienten mit einer antibiotikaresistenten Flora, oder allergischen Reaktionen.The preparation is used in chronic, purulent ailments Processes of the lungs, chronic pneumonia, bronchoectasia, chronic lung abscesses, Lung burn. The success rate in attempts was always higher than the healing effect when using antibiotics. The use of this preparation is particularly topical in patients with an antibiotic-resistant flora, or allergic reactions.
Außer den angegebenen Anwendungsfällen kann das erfindungsgemäße Präparat auch bei Osteomielit, akuter Wundeiterung und aneoroben Infektionen verabreicht werden. Die außergewöhnlich niedrigen Herstellungskosten lassen dieses Präparat bei Massenaffektionen als animikrobe Prophylaxe z.B. bei Strahlenunfällen erscheinen.In addition to the specified applications, the preparation according to the invention can also administered for osteomilitis, acute wound enlargement and aneorobic infections will. The exceptionally low manufacturing costs let this preparation appear as an anti-bacterial prophylaxis in the case of mass affections, e.g. in the event of radiation accidents.
Claims (1)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19803046324 DE3046324A1 (en) | 1980-12-09 | 1980-12-09 | Microbicide effective against microbes which affect the lungs - contains calcium hypochlorite and water which produce hypochlorous acid, which produces iso:hypochlorous acid which releases active oxygen |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19803046324 DE3046324A1 (en) | 1980-12-09 | 1980-12-09 | Microbicide effective against microbes which affect the lungs - contains calcium hypochlorite and water which produce hypochlorous acid, which produces iso:hypochlorous acid which releases active oxygen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3046324A1 true DE3046324A1 (en) | 1982-12-16 |
Family
ID=6118678
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19803046324 Withdrawn DE3046324A1 (en) | 1980-12-09 | 1980-12-09 | Microbicide effective against microbes which affect the lungs - contains calcium hypochlorite and water which produce hypochlorous acid, which produces iso:hypochlorous acid which releases active oxygen |
Country Status (1)
| Country | Link |
|---|---|
| DE (1) | DE3046324A1 (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001013926A2 (en) * | 1999-08-23 | 2001-03-01 | Sterilox Medical (Europe) Limited | Superoxidized water based on hypochlorous acid for the treatment of wounds |
| WO2008112940A1 (en) * | 2007-03-13 | 2008-09-18 | Oculus Innovative Sciences, Inc. | Antimicrobial solutions containing dichlorine monoxide and methods of making and using the same |
| US8840873B2 (en) | 2005-03-23 | 2014-09-23 | Oculus Innovative Sciences, Inc. | Method of treating second and third degree burns using oxidative reductive potential water solution |
| US9782434B2 (en) | 2006-01-20 | 2017-10-10 | Sonoma Pharmaceuticals, Inc. | Methods of treating or preventing inflammation and hypersensitivity with oxidative reductive potential water solution |
| US10342825B2 (en) | 2009-06-15 | 2019-07-09 | Sonoma Pharmaceuticals, Inc. | Solution containing hypochlorous acid and methods of using same |
-
1980
- 1980-12-09 DE DE19803046324 patent/DE3046324A1/en not_active Withdrawn
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001013926A2 (en) * | 1999-08-23 | 2001-03-01 | Sterilox Medical (Europe) Limited | Superoxidized water based on hypochlorous acid for the treatment of wounds |
| WO2001013926A3 (en) * | 1999-08-23 | 2001-09-13 | Sterilox Medical Europ Ltd | Superoxidized water based on hypochlorous acid for the treatment of wounds |
| US7276255B2 (en) | 1999-08-23 | 2007-10-02 | Sterilox Medical (Europe) Limited | Wound and ulcer treatment with super-oxidized water |
| US8632823B2 (en) | 1999-08-23 | 2014-01-21 | Puricore, Inc. | Treatment of infected tissues with hypochlorous acid |
| US8840873B2 (en) | 2005-03-23 | 2014-09-23 | Oculus Innovative Sciences, Inc. | Method of treating second and third degree burns using oxidative reductive potential water solution |
| US9782434B2 (en) | 2006-01-20 | 2017-10-10 | Sonoma Pharmaceuticals, Inc. | Methods of treating or preventing inflammation and hypersensitivity with oxidative reductive potential water solution |
| WO2008112940A1 (en) * | 2007-03-13 | 2008-09-18 | Oculus Innovative Sciences, Inc. | Antimicrobial solutions containing dichlorine monoxide and methods of making and using the same |
| JP2010521489A (en) * | 2007-03-13 | 2010-06-24 | オキュラス イノヴェイティヴ サイエンシズ、インコーポレイテッド | Antibacterial solution containing dichlorine monoxide and method for producing and using the same |
| AU2008224968B2 (en) * | 2007-03-13 | 2013-08-22 | Oculus Innovative Sciences, Inc. | Antimicrobial solutions containing dichlorine monoxide and methods of making and using the same |
| US8784900B2 (en) | 2007-03-13 | 2014-07-22 | Oculus Innovative Sciences, Inc. | Antimicrobial solutions containing dichlorine monoxide and methods of making and using the same |
| US9486479B2 (en) | 2007-03-13 | 2016-11-08 | Oculus Innovative Sciences, Inc. | Antimicrobial solutions containing dichloride monoxide and methods of making and using the same |
| US10342825B2 (en) | 2009-06-15 | 2019-07-09 | Sonoma Pharmaceuticals, Inc. | Solution containing hypochlorous acid and methods of using same |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OAV | Applicant agreed to the publication of the unexamined application as to paragraph 31 lit. 2 z1 | ||
| 8139 | Disposal/non-payment of the annual fee |