DE292149C - - Google Patents
Info
- Publication number
- DE292149C DE292149C DENDAT292149D DE292149DA DE292149C DE 292149 C DE292149 C DE 292149C DE NDAT292149 D DENDAT292149 D DE NDAT292149D DE 292149D A DE292149D A DE 292149DA DE 292149 C DE292149 C DE 292149C
- Authority
- DE
- Germany
- Prior art keywords
- ether
- alcohol
- water
- solution
- preparations
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- RTZKZFJDLAIYFH-UHFFFAOYSA-N diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 16
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 8
- 238000002360 preparation method Methods 0.000 claims description 7
- 150000001447 alkali salts Chemical class 0.000 claims description 4
- 150000001298 alcohols Chemical class 0.000 claims description 3
- 239000002244 precipitate Substances 0.000 claims description 2
- 150000003839 salts Chemical class 0.000 claims description 2
- 239000011780 sodium chloride Substances 0.000 claims description 2
- 238000000034 method Methods 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 7
- CSCPPACGZOOCGX-UHFFFAOYSA-N acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 4
- 239000000843 powder Substances 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- FBPFZTCFMRRESA-KAZBKCHUSA-N D-Mannitol Natural products OC[C@@H](O)[C@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KAZBKCHUSA-N 0.000 description 2
- UNXHWFMMPAWVPI-QWWZWVQMSA-N D-Threitol Natural products OC[C@@H](O)[C@H](O)CO UNXHWFMMPAWVPI-QWWZWVQMSA-N 0.000 description 2
- UNXHWFMMPAWVPI-ZXZARUISSA-N Erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 description 2
- 239000004386 Erythritol Substances 0.000 description 2
- 229940009714 Erythritol Drugs 0.000 description 2
- FBPFZTCFMRRESA-KVTDHHQDSA-N Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 2
- UHOVQNZJYSORNB-UHFFFAOYSA-N benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 2
- 235000019414 erythritol Nutrition 0.000 description 2
- 235000010355 mannitol Nutrition 0.000 description 2
- 239000000594 mannitol Substances 0.000 description 2
- HEBKCHPVOIAQTA-QWWZWVQMSA-N Arabitol Chemical compound OC[C@@H](O)C(O)[C@H](O)CO HEBKCHPVOIAQTA-QWWZWVQMSA-N 0.000 description 1
- QFFVPLLCYGOFPU-UHFFFAOYSA-N Barium chromate Chemical compound [Ba+2].[O-][Cr]([O-])(=O)=O QFFVPLLCYGOFPU-UHFFFAOYSA-N 0.000 description 1
- FBPFZTCFMRRESA-GUCUJZIJSA-N Galactitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-GUCUJZIJSA-N 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000011872 intimate mixture Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
Description
KAISERLICHESIMPERIAL
PATENTAMT.PATENT OFFICE.
Es wurde gefunden, daß man feste, haltbare Präparate von Alkalisalzen des 4It has been found that solid, durable preparations of alkali salts of the 4th
3 · 31-diaminoarsenobenzols gewinnt, indem man Lösungen dieser Salze mit mehrwertigen Al· koholen, wie Mannit, Dulcit, Erythrit, Arabit usw., versetzt und sodann aus solcher Lösung durch Zugabe von indifferenten Mitteln, wie Alkohol und Äther, die neuen Präparate fällt und abtrennt. In denselben liegen nicht neue chemische Verbindungen, sondern innige Gemenge der genannten Alkalisalze mit den mehrwertigen Alkoholen vor. Die neuen Präparate sind zitronengelbe, in Wasser leicht und mit alkalischer Reaktion lösliche, in Alkohol und Äther schwer lösliche Pulver. Im Vergleich zu den reinen Alkalisalzen des Diaminodioxyarsenobenzols sind die neuen Präparate haltbar, namentlich dann, wenn sie unter Luftabschluß aufbewahrt werden.3 · 3 1 -diaminoarsenobenzene is obtained by adding polyhydric alcohols to solutions of these salts, such as mannitol, dulcitol, erythritol, arabitol, etc., and then from such a solution by adding inert agents such as alcohol and ether, the new preparations falls and separates. They do not contain new chemical compounds, but intimate mixtures of the alkali salts mentioned with the polyhydric alcohols. The new preparations are lemon-yellow powders that are easily soluble in water and with an alkaline reaction, and poorly soluble in alcohol and ether. Compared to the pure alkali salts of diaminodioxyarsenobenzene, the new preparations are stable, especially if they are kept in the absence of air.
Zur Darstellung der neuen Präparate verfährt man wie folgt:To display the new preparations, proceed as follows:
i. 47,5 g 4 · 4^DiOXy-S · 31-diaminoarsenobenzolchlorhydrat werden in 200 ecm Wasser gelöst und mit der theoretischen Menge zehnfach normaler Natronlauge versetzt (= 40 ecm). Zu dieser Lösung fügt man 17,2 g Mannit, gelöst in 75 ecm Wasser.i. 47.5 g of 4 · 4 ^ DiOXy-S · 3 1 -diaminoarsenobenzene chlorohydrate are dissolved in 200 ecm of water and mixed with the theoretical amount of ten times normal sodium hydroxide solution (= 40 ecm). 17.2 g of mannitol, dissolved in 75 ecm of water, are added to this solution.
Mischt man die so hergestellte Lösung mit 4 1 absolutem Alkohol und 4 1 Äther, so fällt ein gelbes Pulver aus, das in Wasser leicht, in Alkohol, Äther, Aceton schwer löslich ist.If the solution prepared in this way is mixed with 4 liters of absolute alcohol and 4 liters of ether, it precipitates a yellow powder, which is easily soluble in water but sparingly soluble in alcohol, ether, acetone.
2- 47»5 S 4' 41OiOXy-S · 31-diaminoarsenobenzolchlorhydrat werden in 240 ecm Wasser gelöst, mit 40 ecm zehnfach normaler Na O H versetzt und zu der alkalischen Lösung 12,2 g Erythrit in 40 g Wasser zugegeben. Beim Einfließenlassen der Lösung in Alkohol oder Äther, oder Älkohol-Äthergemisch wird ein gelbes Pulver gefällt, welches sich leicht in Wasser, schwer in Alkohol, Äther, Benzol, Aceton usw. löst. 2-47 »5 S 4 '4-1 OiOXy S · 3 1 -diaminoarsenobenzolchlorhydrat be dissolved in 240 cc of water, mixed with 40 cc of ten times normal Na OH and 12.2 g of erythritol in 40 g of water was added to the alkaline solution. When the solution is poured into alcohol or ether, or a mixture of alcohol and ether, a yellow powder is precipitated which dissolves easily in water, difficult in alcohol, ether, benzene, acetone, etc.
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE292149C true DE292149C (en) |
Family
ID=546954
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DENDAT292149D Active DE292149C (en) |
Country Status (1)
| Country | Link |
|---|---|
| DE (1) | DE292149C (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991011179A1 (en) * | 1990-01-24 | 1991-08-08 | National Research Development Corporation | Aerosol carriers |
| US5376386A (en) * | 1990-01-24 | 1994-12-27 | British Technology Group Limited | Aerosol carriers |
| US5935897A (en) * | 1995-09-12 | 1999-08-10 | Basf Aktiengesellschaft | Monomodal and polymodal catalyst supports and catalysts having narrow pore size distributions and their production |
| US7867937B2 (en) | 2006-12-15 | 2011-01-11 | Exxonmobil Research And Engineering Company | Drying device for producing small quantities of controlled particle size catalysts which are appropriate for use in fluidized bed operations such as fluid catalytic cracking |
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0
- DE DENDAT292149D patent/DE292149C/de active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991011179A1 (en) * | 1990-01-24 | 1991-08-08 | National Research Development Corporation | Aerosol carriers |
| US5376386A (en) * | 1990-01-24 | 1994-12-27 | British Technology Group Limited | Aerosol carriers |
| US5935897A (en) * | 1995-09-12 | 1999-08-10 | Basf Aktiengesellschaft | Monomodal and polymodal catalyst supports and catalysts having narrow pore size distributions and their production |
| US7867937B2 (en) | 2006-12-15 | 2011-01-11 | Exxonmobil Research And Engineering Company | Drying device for producing small quantities of controlled particle size catalysts which are appropriate for use in fluidized bed operations such as fluid catalytic cracking |
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