DE2910627A1 - Implantat als ersatz fuer spongioes aufgebaute knochen - Google Patents

Implantat als ersatz fuer spongioes aufgebaute knochen

Info

Publication number
DE2910627A1
DE2910627A1 DE19792910627 DE2910627A DE2910627A1 DE 2910627 A1 DE2910627 A1 DE 2910627A1 DE 19792910627 DE19792910627 DE 19792910627 DE 2910627 A DE2910627 A DE 2910627A DE 2910627 A1 DE2910627 A1 DE 2910627A1
Authority
DE
Germany
Prior art keywords
implant
network
threads
bone
fibres
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19792910627
Other languages
English (en)
Inventor
Lothar Dr Med Hanslik
Joachim Prof Dr Med Kemssge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
S&G Implants GmbH
Original Assignee
Schuett & Grundei oHG
Schuett & Grundei Sanitaet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schuett & Grundei oHG, Schuett & Grundei Sanitaet filed Critical Schuett & Grundei oHG
Priority to DE19792910627 priority Critical patent/DE2910627A1/de
Publication of DE2910627A1 publication Critical patent/DE2910627A1/de
Withdrawn legal-status Critical Current

Links

Classifications

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    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
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    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/42Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes
    • A61F2/4202Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes for ankles
    • A61F2002/4212Tarsal bones
    • A61F2002/4215Lateral row of tarsal bones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/42Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes
    • A61F2/4202Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes for ankles
    • A61F2002/4223Implants for correcting a flat foot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0008Fixation appliances for connecting prostheses to the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0069Three-dimensional shapes cylindrical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0082Three-dimensional shapes parallelepipedal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00011Metals or alloys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00161Carbon; Graphite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00179Ceramics or ceramic-like structures

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  • Health & Medical Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Prostheses (AREA)

Description

  • Implantat als Ersatz für spongiös aufgebaute
  • Knochen Die Erfindung bezieht sich auf ein Implantat als Ersatz für spongiös aufgebaute Knochen des menschlichen Knochengerüstes. Solche Knochen sind z. B. die Hand- und Fußwurzelknochen, die den Wachstumsfügen benachbarten Abschnitte der Röhrenknochen, die Wirbelkörper, das Becken, die Schulterblätter und große Teile des Schädels und des Brustkorbes.
  • Bei Knochendefekten, Brüchen, Stauchungsbrüchen oder erforderlich werdenden Versteifungen in Knochengelenken, wo bisher spongiöser Knochen zu ersetzen war, geschieht dies bisher durch Verpflanzung (Transplantation) von Knochen, wobei aber die Tragfähigkeit des verpflanzten Knochens über lange Zeit nicht erwartet werden kann, denn der entnommene Knochen verliert durch den Verpflanzungsvorgang seine Knochenzellen infolge der Trennung vom Blutkreislauf, und nur der mineralische knöcherne Bestandteil verbleibt am Ort der Einpflanzung als ein körpereigenes Gerüst, welches aber nicht tragfähig ist und erst mit der Zeit durch Einsprossen von Bindegewebe zu einer neuen Knochenbildung führt. Dieser Vorgang, nämlich die Einorganisierung eines Knochentransplantats in sein knöchernes Lager benötigt - bis zum Erreichen eines voll tragfähigen Knochens lange Zeit, und zwar etwa 1 Jahr.
  • Die Aufgabe der Erfindung besteht darin, Implantate für spongiös aufgebaute zu ersetzende Knochen oder defekte Knochenteile des menschlichen Knochengerüstes so auszubilden, daß der Knochengerüstteil schon nach kurzer Zeit wieder voll belastbar bzw. funktionsfähig ist.
  • Diese Aufgabe wird nach der Erfindung durch ein Implantat gelöst, welches sich durch ein aus körperverträglichen Fäden oder Fasern räumlich aufgebautes, formstabiles Netzwerk kennzeichnet, welches vorzugsweise durchgehend offenzellige bzw offenporige Struktur aufweist.
  • Wird nach dieser Lösung ein Spongiosadefekt mit einem Körper aus dem formstabilen Netzwerk ausgefüllt, --welches aus körperverträglichen Fasern oder Fäden, insbesondere aus Metallen oder Metallegierungen aufgebaut ist, so wird damit sofort die primäre Stabilität gewährleistet und daß Einsprossen von Bindegewebe in das Netzwerk des Implantates mit anschließender Umbildung in Knochen ermöglicht.
  • Dieses spongiöse Implantat verbleibt auf Dauer in seinem Knochenlager und wird mit der Zeit von Knochen umwachsen.
  • Neben Fäden oder Fasern aus Metallen oder Metallegierungen können in gegebenen Fällen auch solche aus Keramikmaterial, Kohle und/oder Kunststoffen zur Anwendung kommen.
  • Um nach der Erfindung die Form des Netzwerkkörpers zu stabilisieren bzw. zu versteifen, können die Fäden oder Fasern an den Kreuzungsstellen z.B. durch Verschweißen oder auf chemischem Wege verbunden werden. Das Implantat aus dem Netzwerk kann durch Prägen oder Pressen in die gewünschte und erforderliche Form gebracht werden oder dadurch, daß eìn Zuschneiden oder Zerteilen aus einem größeren Netzwerkkörper erfolgt.
  • Nach der Erfindung ist es auch möglich, neben dem spongiösen, aus dem Netzwerk bestehenden Implantat das Anwachsen des Implantats durch spongiöse Knochen zu fördern, die neben dem Netzwerk-Implantat bei der primären Implantation verpflanzt werden, wobei die mechanische Beanspruchung von dem implantierten Netzwerk sofort übernommen werden kann.
  • Die Erfindung wird nachstehend anhand von Zeichnungsbeispielen des neuen Netzwerk-Implantats erörtert.
  • Das Implantat als Ersatz für spongiöse Knochen besteht aus Fasern, Fäden oder dünnen Drähten, die zu einem Netzwerk verflochten oder verfilmt sind und aus körperverträglichem Metall (Titan), Metallegierungen, Keramikmaterial, Kohle und ioder Kunststoff bestehen.
  • Die vernetzten oder verfilzten Fäden oder Fasern werden durch Prägen oder Pressen in die für den jeweiligen Knochendefekt erforderliche stabile Form gebracht oder zu einem größeren Körper formstabil vernetzt oder verfilmt, wobei aus diesem Körper die erforderliche Form herausgeschnitten werden kann. Dabei können die Fäden oder Fasern an den Kreuzungsstellen durch Wärmezufuhr (Verschweißen) oder chemisch verbunden werden, um das Netzwerk formstabil zu versteifen.
  • Ist z.B. nach Figur 1 und 2 ein Stauchungsbruch am Schienbeinkopf bzw. am Fersenbein (linker Teil der Figuren 1 und 2) aufgetreten, so wird zur Aufrichtung des zusammengebrochenen spongiösen Knochens ein Schnitt durchgeführt, und die Knochenteile werden auseinandergespreizt und sodann ein entsprechend aus dem Netzwerk bestehendes spongiöses Implantat, z.B. in Form eines Keiles 1 eingesetzt, wobei der Keil so eingebracht werden kann, daß er in seinem Lager fest verklemmt wird, womit das Prinzip der Ruhestellung durch Distraktion verwirklicht ist,so daß unter Umständen Gipsverbände oder sonstige Stütz- und Haltemaßnahrnen erspart werden. In gleicher Weise kann bei einem# durch Stauchung zusammengebrochenen Fersenbein nach Figur 2 vorgegangen werden.
  • Nach Figur 3 ist ein durch Stauchung zusammengebrochener Wirbelknochendefekt in ähnlicher Weise wie zu Figur 1 und 2 auseinandergesetzt ist, operativ zu beheben, indem ein spongiöses Implantat 2, z.B. in Form eines Quaders, in den auseinander zu spreizenden Wirbelknochen unter festen Einspannungen eingesetzt wird.
  • Wenn feste Verbindungen zwischen zwei spongiösen Knochen herzustellen sind, werden gemäß Figur 4 die Knochenflächen so hergerichtet, wie es z.B'. bei einer Gelenkversteifung erforderlich ist. Es wird dann in den Defekt ein spongiöses Implantat 3 z.B.
  • in Form eines Quaders eingesetzt, unter Umständen gemeinsam mit zu transplantierendem spongiösen Knochen, um das schnellere Umwachsen des spongiösen Implantats mit Knochen zu fördern.
  • Das formstabile spongiöse Implantat 3 wird die Versteifung des Gelenkes wegen der größeren primären Stabilität und Formbeständigkeit besser und sicherer als bisher gewährleisten und läßt eine schnellere funktionelle Beanspruchung erwarten.
  • Bei einer Fußgelenkversteifung entsprechend Figur 5, ist, wie nach Figur 4, ebenfalls so vorzugehen, daß Gelenkflächen entsprechend herzurichten sind, z.B. zu resizieren sind, worauf scheibenförmige spongiöse Implantate 4 evtl. auch gemeinsam mit spongiösem Knochen eingesetzt werden, so daß dann durch Einsprossen von Bindegewebe in das spongiöse Implantat die Bildung von spongiösem Knochen erfolgt und damit die Fußgelenkknochen versteift zusammenwachsen.
  • Nach Figur 6 ist es auch möglich, nach Resektion einer Falschgelenkbildung, z.B. eines Oberschenkels, den Defekt durch Einsetzen eines spongiösen Implantates 5 zwischen die beiden Schenkelteile zu ersetzen, wobei dann die beiden Oberschenkelknochenteile miteinander verschient werden können.
  • Nach einem weiteren Fall ist es auch entsprechend Figur 7 und 8 möglich, durch ein spongiöses Implantat 6 einen starren Kern, z.B. den Schaft einer Gelenkkugelproth#ese (Fig,7) bzw. die Schäfte einer Kniegelenkendoprothese (Fig. 8), einzuhüllen, um dadurch eine großflächige Verbindung zum Lagerknochen zu gewährleisten Damit werden günstigere Voraussetzungen für die zementfreie Implantation von Gelenkprothesen im Bereich der Schäfte von Röhrenknochen geschaffen.
  • Nach einem weiteren Beispiel der Fig. 9 kann ein durch ein Geschwulst 7 zerstörter Knochenteil durch ein Implantat 8 aus einem formstabilen Netzwerk nach der Erfindung ersetzt werden.
  • In allen Anwendungsfällen, die nicht durch die Zeichnungsbeispiele beschränkt sind, in denen das spongiöse Implantat nach der Erfindung zur Anwendung kommt, bleibt das Implantat ständig an der Stelle des zu behebenden Defekts und läßt durch seine primäre Stabilität und seine Formbeständigkeit sofort funktionelle Beanspruchungen zu. Das spongiöse Implantat begünstigt das Einsprossen von Bindegewebe und damit die schnelle~Bildung spongiösen Knochens.

Claims (6)

  1. Patentansprüche 1.)Implantat als Ersatz für spongiösen Knochen, gekennzeichnet durch ein aus körperverträglichen Fäden oder Fasern räumlich aufgebautes, formstabiles Netzwerk.
  2. 2. Implantat nach Anspruch 1, dadurch gekennzeichnet, daß die Fäden bzw. Fasern wahlweise aus Metall, Metallegierungen, Keramik, Kohle und/oder Kunststoffen bestehen.
  3. 3. Implantat nach Anspruch 1 oder 2, dadurch gekennzeichnet, daß das Netzwerk in sich durch Verbindung der Fäden an den Kreuzungsstellen versteift ist.
  4. 4. Implantat nach einem der Ansprüche 1 bis 3, dadurch gekennzeichnet, daß das Netzwerk in einer offenen Fassung untergebracht ist.
  5. 5. Implantat nach einem der Ansprüche 1 bis 4, gekennzeichnet durch einen aus dem Netzwerk durch Prägen oder Pressen hergestellten Formkörper, der unmittelbar oder nach Beschneiden oder Zerteilung das Implantat bildet.
  6. 6. Implantat nach einem der Ansprüche 1 bis 5, dadurch gekennzeichnet, daß das Netzwerk in die Form eines Keiles, Quaders, einer Scheibe oder einer einen Kern umgebundenden Hülle gebracht ist.
DE19792910627 1979-03-17 1979-03-17 Implantat als ersatz fuer spongioes aufgebaute knochen Withdrawn DE2910627A1 (de)

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Cited By (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3106917A1 (de) * 1981-02-25 1982-11-25 Schuett & Grundei Med Tech Implantat als ersatz fuer spongioese knochen und verfahren zu seiner herstellung
EP0123426A2 (de) * 1983-03-23 1984-10-31 Kureha Kagaku Kogyo Kabushiki Kaisha Biologisch verträgliches zusammengestelltes Material für Implantate und künstliche Organe für den menschlichen Körper
DE3524020A1 (de) * 1985-03-30 1986-10-02 M A N Technologie GmbH, 8000 München Verfahren zur behandlung von knochenersatz-implantaten
WO1987007827A1 (en) * 1986-06-19 1987-12-30 S + G Implants Gmbh Implant for securing two adjacent vertebrae
EP0338981A1 (de) * 1988-04-22 1989-10-25 Mathys AG Bettlach Markraumsperre
EP0366018A1 (de) * 1988-10-24 1990-05-02 Krysmann, Waldemar, Dr.rer.nat. Metallspongiosa und Verfahren zu ihrer Herstellung
DE3838568A1 (de) * 1988-11-14 1990-05-17 Inst Textil & Faserforschung Gelenkprothese
US5035711A (en) * 1983-03-24 1991-07-30 Kabushiki Kaisya Advance Kaihatsu Kenkyujo Transcutaneously implantable element
US5080673A (en) * 1988-02-03 1992-01-14 Intermedics Orthopedics, Inc. Glenoid prosthesis and method of use
EP0489684A1 (de) * 1990-12-05 1992-06-10 SULZER Medizinaltechnik AG Implantat zum Aufbau von Knochengewebe
DE4208247C1 (de) * 1992-03-14 1993-10-14 Eska Medical Gmbh & Co Implantat als Knochenersatz
EP0631763A1 (de) * 1993-07-01 1995-01-04 SULZER Medizinaltechnik AG Füllkörper aus Metall für Knochenhohlräume
FR2741525A1 (fr) * 1995-11-24 1997-05-30 Voydeville Gilles Cale correctrice orthopedique
US5755809A (en) * 1995-06-07 1998-05-26 Implex Corporation Femoral head core channel filling prothesis
US5993716A (en) * 1990-10-19 1999-11-30 Draenert; Klaus Material and process for its preparation
WO2001049219A1 (en) * 2000-01-06 2001-07-12 Tutogen Medical Gmbh Implant of bone matter
US6554863B2 (en) 1998-08-03 2003-04-29 Synthes Intervertebral allograft spacer
US6632247B2 (en) 2000-03-22 2003-10-14 Synthes (Usa) Implants formed of coupled bone
US6645206B1 (en) 1995-03-27 2003-11-11 Sdgi Holdings, Inc. Interbody fusion device and method for restoration of normal spinal anatomy
EP1371346A1 (de) * 2002-06-14 2003-12-17 Baumgart, Rainer, Dipl.-Ing. Dr. med. Implantierbare Prothese
US6776800B2 (en) 2001-02-28 2004-08-17 Synthes (U.S.A.) Implants formed with demineralized bone
USRE38614E1 (en) 1998-01-30 2004-10-05 Synthes (U.S.A.) Intervertebral allograft spacer
US7066961B2 (en) 1988-06-28 2006-06-27 Gary Karlin Michelson Spinal implant
FR2887760A1 (fr) * 2005-06-30 2007-01-05 Kasios Soc Par Actions Simplif Nouvelle cale destinee a l'osteotomie tibiale ou femorale
US7503933B2 (en) 1995-06-07 2009-03-17 Warsaw Orthopedic, Inc. Lordotic interbody spinal fusion implants
US7691148B2 (en) 1995-06-07 2010-04-06 Warsaw Orthopedic, Inc. Frusto-conical spinal implant
US7828800B2 (en) 1995-06-07 2010-11-09 Warsaw Orthopedic, Inc. Threaded frusto-conical interbody spinal fusion implants
US7837732B2 (en) 2003-11-20 2010-11-23 Warsaw Orthopedic, Inc. Intervertebral body fusion cage with keels and implantation methods
US8043377B2 (en) 2006-09-02 2011-10-25 Osprey Biomedical, Inc. Implantable intervertebral fusion device
ITMO20110115A1 (it) * 2011-05-16 2012-11-17 Caselli Stefano Supporto osteoinduttivo
US9456856B2 (en) 2013-09-26 2016-10-04 Warsaw Orthopedic, Inc. Intrabody osteotomy implant and methods of use
US11931106B2 (en) 2019-09-13 2024-03-19 Treace Medical Concepts, Inc. Patient-specific surgical methods and instrumentation
US11986251B2 (en) 2019-09-13 2024-05-21 Treace Medical Concepts, Inc. Patient-specific osteotomy instrumentation

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DE836999C (de) * 1949-11-26 1952-04-17 Ferrosan As Prothesenkoerper und Verfahren zu ihrer Herstellung
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DE836999C (de) * 1949-11-26 1952-04-17 Ferrosan As Prothesenkoerper und Verfahren zu ihrer Herstellung
DE2142820A1 (de) * 1970-08-26 1972-03-02 Gulf Oil Corp., San Diego, Calif. (V.StA.) Protheseglied

Cited By (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3106917A1 (de) * 1981-02-25 1982-11-25 Schuett & Grundei Med Tech Implantat als ersatz fuer spongioese knochen und verfahren zu seiner herstellung
EP0123426A2 (de) * 1983-03-23 1984-10-31 Kureha Kagaku Kogyo Kabushiki Kaisha Biologisch verträgliches zusammengestelltes Material für Implantate und künstliche Organe für den menschlichen Körper
EP0123426A3 (en) * 1983-03-23 1985-10-23 Kureha Kagaku Kogyo Kabushiki Kaisha Biocompatible composite material for implants and artificial organs for the human body
US5035711A (en) * 1983-03-24 1991-07-30 Kabushiki Kaisya Advance Kaihatsu Kenkyujo Transcutaneously implantable element
DE3524020A1 (de) * 1985-03-30 1986-10-02 M A N Technologie GmbH, 8000 München Verfahren zur behandlung von knochenersatz-implantaten
WO1987007827A1 (en) * 1986-06-19 1987-12-30 S + G Implants Gmbh Implant for securing two adjacent vertebrae
US5080673A (en) * 1988-02-03 1992-01-14 Intermedics Orthopedics, Inc. Glenoid prosthesis and method of use
EP0338981A1 (de) * 1988-04-22 1989-10-25 Mathys AG Bettlach Markraumsperre
US7066961B2 (en) 1988-06-28 2006-06-27 Gary Karlin Michelson Spinal implant
EP0366018A1 (de) * 1988-10-24 1990-05-02 Krysmann, Waldemar, Dr.rer.nat. Metallspongiosa und Verfahren zu ihrer Herstellung
DE3838568A1 (de) * 1988-11-14 1990-05-17 Inst Textil & Faserforschung Gelenkprothese
US5993716A (en) * 1990-10-19 1999-11-30 Draenert; Klaus Material and process for its preparation
EP0489684A1 (de) * 1990-12-05 1992-06-10 SULZER Medizinaltechnik AG Implantat zum Aufbau von Knochengewebe
US5147402A (en) * 1990-12-05 1992-09-15 Sulzer Brothers Limited Implant for ingrowth of osseous tissue
DE4208247C1 (de) * 1992-03-14 1993-10-14 Eska Medical Gmbh & Co Implantat als Knochenersatz
EP0631763A1 (de) * 1993-07-01 1995-01-04 SULZER Medizinaltechnik AG Füllkörper aus Metall für Knochenhohlräume
US5665119A (en) * 1993-07-01 1997-09-09 Sulzer Medizinaltechnik Ag Filling member made from metal for bone cavities
US6645206B1 (en) 1995-03-27 2003-11-11 Sdgi Holdings, Inc. Interbody fusion device and method for restoration of normal spinal anatomy
US7942933B2 (en) 1995-06-07 2011-05-17 Warsaw Orthopedic, Inc. Frusto-conical spinal implant
US7789914B2 (en) 1995-06-07 2010-09-07 Warsaw Orthopedic, Inc. Implant having arcuate upper and lower bearing surfaces along a longitudinal axis
US8858638B2 (en) 1995-06-07 2014-10-14 Warsaw Orthopedic, Inc. Spinal implant
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