DE2861502D1 - New indole derivatives, processes for their preparation, and pharmaceutical compositions containing them. - Google Patents

New indole derivatives, processes for their preparation, and pharmaceutical compositions containing them.

Info

Publication number
DE2861502D1
DE2861502D1 DE7878100274T DE2861502T DE2861502D1 DE 2861502 D1 DE2861502 D1 DE 2861502D1 DE 7878100274 T DE7878100274 T DE 7878100274T DE 2861502 T DE2861502 T DE 2861502T DE 2861502 D1 DE2861502 D1 DE 2861502D1
Authority
DE
Germany
Prior art keywords
processes
preparation
pharmaceutical compositions
compositions containing
indole derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE7878100274T
Other languages
German (de)
Inventor
Paul Dr Stadler
Franz Dr Troxler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz Patent GmbH
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Application granted granted Critical
Publication of DE2861502D1 publication Critical patent/DE2861502D1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE7878100274T 1977-07-12 1978-06-29 New indole derivatives, processes for their preparation, and pharmaceutical compositions containing them. Expired DE2861502D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH858977 1977-07-12
CH300878 1978-03-20

Publications (1)

Publication Number Publication Date
DE2861502D1 true DE2861502D1 (en) 1982-02-25

Family

ID=25691930

Family Applications (1)

Application Number Title Priority Date Filing Date
DE7878100274T Expired DE2861502D1 (en) 1977-07-12 1978-06-29 New indole derivatives, processes for their preparation, and pharmaceutical compositions containing them.

Country Status (14)

Country Link
EP (1) EP0000355B1 (en)
JP (1) JPS5436259A (en)
AU (1) AU521641B2 (en)
CA (1) CA1114381A (en)
DE (1) DE2861502D1 (en)
DK (1) DK300978A (en)
ES (1) ES471593A1 (en)
FI (1) FI782138A (en)
IE (1) IE47209B1 (en)
IL (1) IL55116A (en)
IT (1) IT7850140A0 (en)
NZ (1) NZ187813A (en)
PH (1) PH14993A (en)
PT (1) PT68270A (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2960547D1 (en) * 1978-02-24 1981-11-05 Pfizer Ltd 3-(imidazol-1-ylalkyl)indoles as selective inhibitors of thromboxane synthetase,pharmaceutical compositions thereof, and methods for preparing them
US4634713A (en) * 1982-05-28 1987-01-06 Ciba-Geigy Corporation Antihypertensive 3-(ureidocyclohexyleneamino)propane-1,2-diol derivatives
JPH0283380A (en) * 1988-09-21 1990-03-23 Kotobuki Seiyaku Kk Novel diamine derivative, antiarrhythmic agent and production thereof
FR2642422A1 (en) * 1988-12-22 1990-08-03 Roussel Uclaf NOVEL ACYLATED POLYAMINES, PROCESS FOR PREPARING THEM AND THEIR APPLICATION AS FUNGICIDES
DE69430861T2 (en) * 1993-04-07 2003-01-23 Otsuka Pharma Co Ltd N-ACYLATED 4-AMINOPIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS OF PERIPHERAL VESSEL WIDING AGENTS
MY142362A (en) 2004-01-29 2010-11-30 Otsuka Pharma Co Ltd Pharmaceutical composition for promoting angiogenesis
US11764679B2 (en) 2020-01-15 2023-09-19 Solaredge Technologies Ltd. Power device
CN115433164B (en) * 2022-09-14 2023-12-12 南京师范大学 Nicotinamide derivative, preparation method thereof and application thereof in resisting aging and prolonging life

Also Published As

Publication number Publication date
FI782138A (en) 1979-01-13
NZ187813A (en) 1981-03-16
AU3793978A (en) 1980-01-17
DK300978A (en) 1979-01-13
EP0000355A1 (en) 1979-01-24
JPS5436259A (en) 1979-03-16
IE781382L (en) 1979-01-12
IL55116A (en) 1982-02-28
IT7850140A0 (en) 1978-07-03
IL55116A0 (en) 1978-09-29
ES471593A1 (en) 1979-10-01
PH14993A (en) 1982-03-22
EP0000355B1 (en) 1982-01-06
IE47209B1 (en) 1984-01-11
PT68270A (en) 1978-08-01
AU521641B2 (en) 1982-04-22
CA1114381A (en) 1981-12-15

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: SANDOZ-PATENT-GMBH, 7850 LOERRACH, DE

8339 Ceased/non-payment of the annual fee