DE202005020103U1 - Food auxiliary agent, useful for preventing prostate complaints, comprises pomegranate flour, pomegranate extract, rye powder, agraricus-agaric powder, rosemary powder, saw palmetto extract, white tea extract and curcumin extract - Google Patents

Food auxiliary agent, useful for preventing prostate complaints, comprises pomegranate flour, pomegranate extract, rye powder, agraricus-agaric powder, rosemary powder, saw palmetto extract, white tea extract and curcumin extract Download PDF

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DE202005020103U1
DE202005020103U1 DE202005020103U DE202005020103U DE202005020103U1 DE 202005020103 U1 DE202005020103 U1 DE 202005020103U1 DE 202005020103 U DE202005020103 U DE 202005020103U DE 202005020103 U DE202005020103 U DE 202005020103U DE 202005020103 U1 DE202005020103 U1 DE 202005020103U1
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extract
powder
pomegranate
white tea
curcumin
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CHINA VITAL MED E K
CHINA VITAL MED EK
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives

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  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Botany (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Food auxiliary agent (A) (in the form of capsule or powder) useful for preventing prostate complaints, comprises pomegranate flour, pomegranate extract (40% ellagic acid), rye powder, agraricus-agaric powder, rosemary powder, saw palmetto extract, white tea extract and curcumin extract. ACTIVITY : Cytostatic. MECHANISM OF ACTION : None given.

Description

Die vorliegende Erfindung betrifft ein Nahrungsergänzungsmittel zur Verwendung oder zur Vorbeugung bei Prostatabeschwerden.The The present invention relates to a nutritional supplement for use or to prevent prostate discomfort.

Die gutartige Vergrößerung der Prostata, medizinisch Benigne Prostatahyperplasie (BPH) genannt, entsteht mit zunehmendem Alter. Dabei handelt es sich um eine Zunahme des Prostatavolumens bedingt durch gutartige, hormonbedingte Zellwucherungen im Prostatagewebe. Dabei kommt es zu Harnabflussstörungen beziehungsweise zum Harn-Rückstau. Die akute Prostatitis ist eine entzündliche Erkrankung der Prostata. Bakterien und Parasiten gelangen durch die Harnröhre oder auf dem Blutweg in die Prostata und verursachen eine akute eitrige Infektion. Bei der chronischen Prostatitis handelt es sich um eine bakteriell bedingte Prostataentzündung, die aus einer nicht ausgeheilten akuten Prostatitis entstanden ist. Prostatasteine und Prostatakrebs sind weitere Krankheiten und Beschwerden, die sehr häufig auftreten.The benign enlargement of the Prostate, medically called Benign Prostatic Hyperplasia (BPH), arises with increasing age. This is an increase in the Prostate volume due to benign, hormone-induced cell proliferation in prostate tissue. This leads to urinary drainage disorders or to the urine backwater. Acute prostatitis is an inflammatory disease of the prostate. Bacteria and parasites enter through the urethra or on the bloodstream the prostate and cause an acute purulent infection. In the Chronic prostatitis is a bacterial prostatitis, the originated from an unhealed acute prostatitis. Prostate stones and prostate cancer are other diseases and ailments, the very common occur.

Es ist bekannt, dass Substanzen des Granatapfels sowohl präventive als auch heilende Wirkung bei Krebserkrankungen haben können. Des Weiteren ist bekannt, dass Roggenpollen und -extrakte zur Behandlung der altersbedingten Vergrößerung der Prostata eingesetzt werden. Schließlich werden die Früchte der Sägepalme unter anderem zur Besserung der klinischen Parameter bei benigner Prostatahypertrophie eingesetzt. Es ergibt sich dabei ein positiver Einfluss auf Nykturie, Pollakisurie, Uroflow, Restharnmenge. Weißem Tee werden die besten krebsvorbeugenden Inhaltsstoffe von allen Teesorten nachgesagt.It It is known that pomegranate substances are both preventive as well as have healing properties in cancers. Of Furthermore, it is known that rye pollen and extracts for treatment the age - related enlargement of the Prostate be used. Finally, the fruits of the saw palmetto among other things, to improve the clinical parameters in benigner Prostatic hypertrophy used. This results in a positive Influence on Nocturia, Pollakisuria, Uroflow, residual urine amount. White tea Become the Best Cancer Preventive Ingredients of All Teas rumored.

Aufgabe der vorliegenden Erfindung war es, ein Nahrungsergänzungsmittel bereitzustellen, welches eine generell vorbeugende und heilende bzw. lindernde Wirkung bei Prostatabeschwerden aufweist.task The present invention was a dietary supplement to provide a generally preventive and curative or soothing effect on prostate problems.

Gelöst wird diese Aufgabe durch einen Nahrungsergänzungsmittel mit den Merkmalen des Schutzanspruchs 1.Is solved this task through a dietary supplement with the characteristics of the protection claim 1.

Vorteilhafte Ausgestaltungen sind in den Unteransprüchen beschrieben.advantageous Embodiments are described in the subclaims.

Ein erfindungsgemäßes Nahrungsergänzungsmittel zur Verwendung oder zur Vorbeugung bei Prostatabeschwerden als Kapsel- oder Pulverdarreichung umfasst eine Kombination aus

  • (a) Granatapfelmehl;
  • (b) Granatapfelextrakt (40% Ellagsäure);
  • (c) Roggenpulver;
  • (d) Agraricus-Pilzpulver;
  • (e) Rosmarinpulver;
  • (f) Sägepalmenextrakt,
  • (g) Weißer-Tee-Extrakt; und
  • (h) Curcumin-Extrakt.
A nutritional supplement according to the invention for the use or prevention of prostate problems as capsule or powder administration comprises a combination of
  • (a) pomegranate flour;
  • (b) pomegranate extract (40% ellagic acid);
  • (c) rye powder;
  • (d) agricultured mushroom powder;
  • (e) rosemary powder;
  • (f) saw palmetto extract,
  • (g) white tea extract; and
  • (h) curcumin extract.

In einer vorteilhaften Zusammensetzung enthält das erfindungsgemäßeIn an advantageous composition contains the inventive

Nahrungsergänzungsmittel die genannten Bestandteile in folgenden Mengen (pro 100 g: (a) Granatapfelmehl 10 – 25 g; (b) Granatapfelextrakt (40% Ellagsäure) 10 – 25 g; (c) Roggenpulver 5 – 15 g; (d) Agraricus-Pilzpulver 5 – 15 g; (e) Rosmarinpulver 2 – 10 g; (f) Sägepalmenextrakt 0,5 – 5 g; (g) Weißer-Tee-Extrakt 0,5 – 5 g; und (h) Curcumin-Extrakt 0,5 – 5 g. Nutritional supplement the said ingredients in the following quantities (per 100 g: (a) Pomegranate flour 10 - 25 g; (b) pomegranate extract (40% ellagic acid) 10 - 25 g; (c) rye powder 5 - 15 g; (d) Agraricus mushroom powder 5 - 15 g; (e) rosemary powder 2 - 10 g; (f) saw palmetto extract 0.5 - 5 g; (g) White tea extract 0.5 - 5 g; and (h) curcumin extract 0.5 - 5 g.

Überraschenderweise hat sich gezeigt, dass durch die genannte Kombination der Inhaltsstoffe bzw. Wirkstoffe im erfindungsgemäßen Nahrungsergänzungsmittel die genannten Prostatabeschwerden in signifikant nachweisbaren Umfang gelindert werden konnten. Dadurch kann das Nahrungsergänzungsmittel auch zur Vorbeugung gegen diese Beschwerden angewendet werden. Insbesondere die im Grantapfel in hohen Konzentrationen anzutreffende Ellagsäure zeigt eine krebsvorbeugende, insbesondere prostatakrebsvorbeugende Wirkung. Entsprechendes gilt für den Weißen-Tee-Extrakt. Verantwortlich hierfür ist der Inhaltsstoff Epigallocatechingallat (EGCG), ein Hauptbestandteil der Gerbstoffe. EGCG zeigt bei entsprechend hoher Dosis eine antikarzinogene Wirkung bei Tumoren und Metastasen. Der Weiße-Tee-Extrakt enthält dabei bis zu 30% EGCG. Der Zusatz an Agraricus-Pilzpulver und Rosmarinpulver wirkt dabei durchblutungsfördernd, der Curcumin-Extrakt weist cytotoxische Eigenschaften auf, eine Induzierung von Tumoren unterbinden kann.Surprisingly, it has been shown that the above-mentioned combination of ingredients or active ingredients in dietary supplements according to the invention said prostate complaints could be alleviated to a significantly detectable extent. Thus, the dietary supplement can also be used to prevent these symptoms. In particular, the ellagic acid found in the cultivated apple in high concentrations shows a cancer-preventing, in particular prostate cancer-preventing effect. The same applies to the white tea extract. Responsible for this is the ingredient Epi gallocatechin gallate (EGCG), a major component of tannins. EGCG shows an anti-carcinogenic effect on tumors and metastases at a correspondingly high dose. The white tea extract contains up to 30% EGCG. The addition of Agraricus mushroom powder and rosemary powder acts to promote blood circulation, the curcumin extract has cytotoxic properties, can prevent an induction of tumors.

Für die Herstellung des Granatapfelmehls wird die gesamte Frucht verwendet. Es ist aber auch möglich nur Pulver der Kerne oder der Schale zu verwenden. Der Granatapfelextrakt enthält 20 – 40% Ellagsäure. Zur Herstellung des Rosmarinpulvers und des Sägepalmenextraktes werden die jeweiligen Pflanzenblätter verwendet.For the production of pomegranate flour, the entire fruit is used. But it is also possible to use only powder of the kernels or the shell. The pomegranate extract contains 20 - 40% Ellagic acid. to Production of rosemary powder and saw palmetto extract are becoming respective plant leaves used.

In einer weiteren vorteilhaften Zusammensetzung weist das erfindungsgemäße Nahrungsergänzungsmittel weiterhin die Vitamine C und E auf. Dabei kann das Nahrungsergänzungsmittel pro 100 g 5 – 15 g Vitamin C und 2 – 10 g Vitamin E enthalten. Zudem kann das Nahrungsergänzungsmittel pro 100 g 2 – 10 g Zinkgluconat und 0,01 – 0,05 g Natriumselenit enthalten. Durch die Vitaminzugaben werden einerseits Antioxidantien in ausreichender Menge dem Körper zur Verfügung gestellt. Andererseits wird die gleichzeitige Zugabe von Zinkgluconat Zink als lebenswichtiges Spurenelement dem Körper zugeführt und deckt so einen erhöhten Bedarf an Zink, insbesondere bei Erkrankungen der Prostata. Selen wirkt zusam men mit Vitamin E Fänger freier Radikale und schützt somit die Zellen vor aggressiven Sauerstoffverbindungen. Durch diese zellschützende Funktion kann es krebsvorbeugend wirken
In einer erfindungsgemäßen Ausgestaltung des Nahrungsergänzungsmittels wird dieses in pulvriger oder fester Form in der Kapsel, insbesondere in einer Cellulosekapsel eingebunden. Dabei kann das Nahrungsergänzungsmittel pro 100 g 10 – 20 g Hydroxypropylmethylcellulose enthalten. Anteile an Magnesiumstearat (0,5 – 1,5 g/100 g) dienen als Gleitmittel zur vereinfachten Einnahme des Nahrungsergänzungsmittels.In a further advantageous composition, the dietary supplement according to the invention furthermore comprises vitamins C and E. The dietary supplement may contain 5 to 15 g of vitamin C and 2 to 10 g of vitamin E per 100 g. In addition, the dietary supplement per 100 g may contain 2-10 g of zinc gluconate and 0.01-0.05 g of sodium selenite. By the addition of vitamins, on the one hand, antioxidants are provided in sufficient quantity to the body. On the other hand, the simultaneous addition of zinc gluconate zinc as a vital trace element is supplied to the body and thus covers an increased demand for zinc, especially in diseases of the prostate. Selenium works together with vitamin E scavenger free radicals and thus protects the cells from aggressive oxygen compounds. Due to this cell-protective function, it can be cancer-preventive
In an embodiment of the dietary supplement according to the invention, the latter is incorporated in powdered or solid form in the capsule, in particular in a cellulose capsule. The dietary supplement may contain 10-20 g of hydroxypropylmethylcellulose per 100 g. Levels of magnesium stearate (0.5 - 1.5 g / 100 g) serve as a lubricant for simplified intake of the dietary supplement.

Es ist aber auch denkbar, das Nahrungsergänzungsmittel in flüssiger Form bereitzustellen.It But it is also conceivable, the dietary supplement in liquid form provide.

Ein Ausführungsbeispiel der erfindungsgemäßen Nahrungsergänzungsmittel in Kapselform weist folgende Zusammensetzung pro 100 g auf: 16,70 g Granatapfelmehl, 15,03 g Hydroxypropylmethylcellulose, 14,61 g Granatapfelextrakt (40% Ellagsäure), 11,69 g Roggenpollen, 9,19 g Agraricus-Pilzpulver, 7,52 g Vitamin C, 6,68 g Rosmarinpulver, 5,97 g alpha-Tocopherylacetat, 4,66 g Zinkgluconat, 2,51 g Sägepalmenextrakt (25%), 1,67 g Weißer-Tee-Extrakt (30% EGCG), 1,25 g Curcumin-Extrakt (95%), 0,84 g Magnesiumstearat und 0,02 g Natriumselenit. Als Extraktionsmittel für die Extrakte oder Trockenextrakte eignen sich Ethanol-Wasser-Mischungen oder Methanol-Wasser-Mischungen.One embodiment the dietary supplement according to the invention in capsule form has the following composition per 100 g: 16.70 pomegranate flour, 15.03 g hydroxypropyl methylcellulose, 14.61 g Pomegranate extract (40% ellagic acid), 11.69 g of rye pollen, 9.19 g of agro-fungus powder, 7.52 g of vitamin C, 6.68 g Rosemary powder, 5.97 g alpha-tocopheryl acetate, 4.66 g zinc gluconate, 2.51 g saw palmetto extract (25%), 1.67 g white tea extract (30% EGCG), 1.25 g of curcumin extract (95%), 0.84 g of magnesium stearate and 0.02 g of sodium selenite. As extractant for the extracts or dry extracts are suitable ethanol-water mixtures or Methanol-water mixtures.

Claims (9)

Nahrungsergänzungsmittel zur Verwendung oder zur Vorbeugung bei Prostatabeschwerden als Kapsel- oder Pulverdarreichung umfassend eine Kombination aus: (a) Granatapfelmehl; (b) Granatapfelextrakt (40% Ellagsäure); (c) Roggenpulver; (d) Agraricus-Pilzpulver; (e) Rosmarinpulver; (f) Sägepalmenextrakt, (g) Weißer-Tee-Extrakt; und (h) Curcumin-Extrakt.Dietary supplements for use or prevention in prostate problems as a capsule or Powder delivery comprising a combination of: (a) pomegranate flour; (B) Pomegranate extract (40% ellagic acid); (C) Rogge powder; (d) agricultured mushroom powder; (e) rosemary powder; (F) Saw Palmetto, (G) White tea extract; and (h) curcumin extract. Nahrungsergänzungsmittel nach Anspruch 1 enthaltend folgende Inhaltsstoffe pro 100 g: (a) Granatapfelmehl 10 – 25 g; (b) Granatapfelextrakt (40% Ellagsäure) 10 – 25 g; (c) Roggenpulver 5 – 15 g; (d) Agraricus-Pilzpulver 5 – 15 g; (e) Rosmarinpulver 2 – 10 g; (f) Sägepalmenextrakt 0,5 – 5 g;
(g) Weißer-Tee-Extrakt 0,5 – 5 g; und (h) Curcumin-Extrakt 0,5 – 5 g.
Dietary supplement according to claim 1 containing the following ingredients per 100 g: (a) Pomegranate flour 10 - 25 g; (b) pomegranate extract (40% ellagic acid) 10 - 25 g; (c) rye powder 5 - 15 g; (d) Agraricus mushroom powder 5 - 15 g; (e) rosemary powder 2 - 10 g; (f) saw palmetto extract 0.5 - 5 g;
(g) White tea extract 0.5 - 5 g; and (h) curcumin extract 0.5 - 5 g.
Nahrungsergänzungsmittel nach Anspruch 1 oder 2, gekennzeichnet durch dass das Nahrungsergänzungsmittel die Vitamine C und E enthält.Nutritional supplement according to claim 1 or 2, characterized in that the food supplement containing vitamins C and E. Nahrungsergänzungsmittel nach Anspruch 3 enthaltend folgende Inhaltsstoffe pro 100 g: 5 – 15 g Vitamin C und 2 – 10 g Vitamin E.Dietary supplements according to claim 3 containing the following ingredients per 100 g: 5 - 15 g of vitamin C and 2 - 10 g Vitamin E. Nahrungsergänzungsmittel nach einem der vorhergehenden Ansprüche, dadurch gekennzeichnet dass das Nahrungsergänzungsmittel Zinkgluconat enthält.Dietary supplements according to one of the preceding claims, characterized that the nutritional supplement Contains zinc gluconate. Nahrungsergänzungsmittel nach Anspruch 5 enthaltend folgende Inhaltsstoffe pro 100 g: 2 – 10 g Zinkgluconat.Dietary supplements according to claim 5 containing the following ingredients per 100 g: 2 - 10 g zinc gluconate. Nahrungsergänzungsmittel nach einem der Ansprüche 1 bis 6, dadurch gekennzeichnet, dass das Nahrungsergänzungsmittel in pulvriger oder fester Form in der Kapsel, insbesondere in einer Cellulosekapsel eingebunden ist.Dietary supplements according to one of the claims 1 to 6, characterized in that the dietary supplement in powdery or solid form in the capsule, especially in one Cellulose capsule is involved. Nahrungsergänzungsmittel nach Anspruch 7 enthaltend folgende Inhaltsstoffe pro 100 g: 10 – 20 g Hydroxypropylmethylcellulose.Dietary supplements according to claim 7 containing the following ingredients per 100 g: 10-20 g of hydroxypropylmethylcellulose. Nahrungsergänzungsmittel nach einem der vorhergehenden Ansprüche enthaltend folgende Inhaltsstoffe pro 100 g: 0,01 – 0,05 g Natriumselenit.Dietary supplements according to one of the preceding claims comprising the following ingredients per 100 g: 0.01-0.05 g sodium selenite.
DE202005020103U 2005-12-23 2005-12-23 Food auxiliary agent, useful for preventing prostate complaints, comprises pomegranate flour, pomegranate extract, rye powder, agraricus-agaric powder, rosemary powder, saw palmetto extract, white tea extract and curcumin extract Expired - Lifetime DE202005020103U1 (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009007360A1 (en) * 2007-07-10 2009-01-15 Unilever Plc Stable and consumable compositions
WO2010012651A2 (en) * 2008-07-31 2010-02-04 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Composition useful for the prevention or reduction of the progression of prostate cancer
WO2011124573A1 (en) * 2010-04-09 2011-10-13 Unilever Plc Oral care compositions
US8574602B2 (en) 2009-04-20 2013-11-05 Conopco, Inc. Stabilized cationic ammonium compounds for topical compositions
ES2440168A1 (en) * 2012-07-27 2014-01-27 Vitalgrana Pomegranate, S.L Pomegranate flour and its obtaining procedure (Machine-translation by Google Translate, not legally binding)
US8765793B2 (en) 2009-09-15 2014-07-01 Conopco, Inc. Compositions with skin benefit compounds and chelator stabilized cationic ammonium compounds

Cited By (17)

* Cited by examiner, † Cited by third party
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US8945655B2 (en) 2007-07-10 2015-02-03 Conopco, Inc. Stable and consumable compositions
EA018366B1 (en) * 2007-07-10 2013-07-30 Унилевер Н.В. Consumable green tea beverage and method for making same
WO2009007360A1 (en) * 2007-07-10 2009-01-15 Unilever Plc Stable and consumable compositions
WO2010012651A2 (en) * 2008-07-31 2010-02-04 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Composition useful for the prevention or reduction of the progression of prostate cancer
WO2010012651A3 (en) * 2008-07-31 2010-04-01 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Composition useful for the prevention or reduction of the progression of prostate cancer
AU2009276035B2 (en) * 2008-07-31 2015-10-01 Alfasigma S.p.A Composition useful for the prevention or reduction of the progression of prostate cancer
US20110262417A1 (en) * 2008-07-31 2011-10-27 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Composition useful for the prevention or reduction of the progression of prostate cancer
JP2011529465A (en) * 2008-07-31 2011-12-08 シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ Composition effective to prevent or reduce progression of prostate cancer
CN102112141B (en) * 2008-07-31 2013-03-06 希格马托制药工业公司 Composition useful for prevention or reduction of progression of prostate cancer
US9084812B2 (en) 2008-07-31 2015-07-21 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A Composition useful for the prevention or reduction of the progression of prostate cancer
US8758835B2 (en) 2008-07-31 2014-06-24 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Composition useful for the prevention or reduction of the progression of prostate cancer
EA019814B1 (en) * 2008-07-31 2014-06-30 Сигма-Тау Индустрие Фармасьютике Риуните С.П.А. Composition useful for the prevention or reduction of the progression of prostate cancer
US8574602B2 (en) 2009-04-20 2013-11-05 Conopco, Inc. Stabilized cationic ammonium compounds for topical compositions
US8765793B2 (en) 2009-09-15 2014-07-01 Conopco, Inc. Compositions with skin benefit compounds and chelator stabilized cationic ammonium compounds
US8916139B2 (en) 2010-04-09 2014-12-23 Conopco, Inc. Oral care compositions
WO2011124573A1 (en) * 2010-04-09 2011-10-13 Unilever Plc Oral care compositions
ES2440168A1 (en) * 2012-07-27 2014-01-27 Vitalgrana Pomegranate, S.L Pomegranate flour and its obtaining procedure (Machine-translation by Google Translate, not legally binding)

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