DE20003349U1 - Vorrichtung für die thermische Behandlung von biologischem Gewebe - Google Patents
Vorrichtung für die thermische Behandlung von biologischem GewebeInfo
- Publication number
- DE20003349U1 DE20003349U1 DE20003349U DE20003349U DE20003349U1 DE 20003349 U1 DE20003349 U1 DE 20003349U1 DE 20003349 U DE20003349 U DE 20003349U DE 20003349 U DE20003349 U DE 20003349U DE 20003349 U1 DE20003349 U1 DE 20003349U1
- Authority
- DE
- Germany
- Prior art keywords
- puncture shaft
- puncture
- shaft
- handpiece
- laser
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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Classifications
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- A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
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- A61B8/0833—Detecting organic movements or changes, e.g. tumours, cysts, swellings involving detecting or locating foreign bodies or organic structures
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medical Informatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Optics & Photonics (AREA)
- Radiology & Medical Imaging (AREA)
- Electromagnetism (AREA)
- Otolaryngology (AREA)
- Biophysics (AREA)
- Laser Surgery Devices (AREA)
Description
10
Anwendung finden die oben beschriebenen Systeme zur Verödung von Weichteiltumoren in unterschiedlichen Organen, insbesondere in Leber, Prostata und Gehirn.
Bei dem bisher üblichen minimal-invasiven Vorgehen erfolgt als erstes die Punktion des Tumors durch die Haut hindurch unter lokaler Betäubung und bildgebender Kontrolle mittels Röntgen-Computertomographie oder Magnetresonanz-Tomographie. Sodann wird in einem weiteren Arbeitsschritt der flexible Hüllkatheter im Punktionskanal mittels Schleusensystem positioniert und anschließend der eigentliche Laserapplikator eingeführt.
Als nachteilig bei dem beschriebenen Vorgehen hat sich jedoch herausgestellt, daß bei stark durchbluteten Organen wie der Leber oder der Niere ein Großteil der eingebrachten Energie durch den Blutstrom wieder abtransportiert wird und somit verloren geht, so daß gerade bei sehr großen Tumoren häufig mehrere synchrone 5 oder asynchrone Laserapplikationen erforderlich sind.
5
35
In einem bevorzugten Ausführungsbeispiel wird durch die Verwendung von Quarzglas bzw. Saphir als transparentem Hohlzylinder im Vergleich zu den bestehenden Systemen ein um den Faktor vier verbesserter Abtransport überschüssiger Wärme aus dem Gewebe ermöglicht. Weiterhin wurde erkannt, daß durch den hohen Schmelzpunkt von Glas die thermische Zerstörschwelle deutlich heraufgesetzt wird, so daß die Laserverödung sicherer durchgeführt werden kann. Um dem Anwender eine Orientierung zu ermöglichen und eine reproduzierbare Position des Punktionsschaftes im Körpergewebe zu gewährleisten, ist der Stabilisierungsmantel vorzugsweise mit äquidistanten Markierungen versehen.
In einer Variante wird dem Fluid in bekannter Weise eine streuende Substanz zugesetzt, um die Abstrahleigenschaften des weiter unten beschriebenen Diffusorelementes zu verbessern. In einer speziellen Ausführungsform kann sogar auf das Diffusorelement ganz verzichtet werden und die aus dem Lichtwellenleiter prograd austretende Strahlung durch die im Fluid gelöste lichtstreuende Substanz homogen verteilt werden. In einer weiteren Variante wird dem Fluid ein Ultraschallkontrastmittel zugesetzt, um die Lokalisation des gesamten durchströmten Schaftes im Körpergewebe bei Verwendung des bildgebenden Ultraschalls zu erleichtern. In einer weiteren Ausführungsform wird dem Fluid ein 0 Magnetresonanz-Kontrastmittel zugesetzt, um die Lokalisation bei Verwendung im vorzugsweise offenen Magnetresonanz-Tomographen zu erleichtern.
In einer weiteren Ausführungsvariante wird anstelle der Temperatur die sogenannte Autofluoreszenz des Gewebes bei Anregung im Wellenlängenbereich 200 bis 700 nm als Vitalparameter für die Beurteilung der vollständigen thermischen GewebeVerödung genutzt. Das verstärkte oder abgeschwächte Auftreten bestimmter Fluoreszenzbanden (z.B. NADH-Fluoreszenz) ist ein Maß für den vitalen Gewebezustand und kann zur Steuerung bzw. Regelung der Laserausgangsleistung verwendet werden.
100 | Lasersystem |
101 | externer Lichtwellenleiter |
102 | Handstück der Applikationsvorrichtung |
103 | Punktionsschaft der Applikationsvorrichtung |
104 | Körpergewebe |
105 | Vorratsbehälter |
106 | zuführender Schlauch |
107 | Pumpe |
108 | rückführender Schlauch |
109 | Auffangbehälter |
110 | Ultraschallscanner |
111 | Ultraschallgerät |
112 | Meßsonde |
113 | Führungsarm |
114 | Meßeinrichtung |
115 | Regelstrecke |
116 | Isotherme |
117 | Adapter |
1 | transparenter Hohlzylinder |
2,2' | starrer Stabilisierungsmantel |
3 | distales Ende des Stabilisierungsmantels |
4,4' | Anschlußstück |
5 | Schlauch |
6 | Fluid |
7,7' | ,7'' Spitze |
8 | Diffusorelement |
9 | interner Lichtwellenleiter |
10 | Markierungen |
11 | Anschlußstutzen |
12 | Anschlußstutzen |
13 | Verteilungssystem |
14 | Dichtring |
«9« · · Φ Φ ΦΦ ΦΦ ΦΦ · · ΦΦΦ* ΦΦΦΦΦ ΦΦ Φ Φ *
• » · ········ Φ · · · » · · .· • « ··« · · Φ &phgr; Φ Φ Φ Φ ΦΦΦΦΦ ΦΦ Φ 9·« · · &phgr; Φ Φ Φ Φ Φ Φ ΦΦΦΦ ♦·· ΦΦΦ 9 &phgr; Φ ΦΦΦΦΦΦΦΦΦΦΦ· * ·ΦΦ 9ΦΦ 9··Φ ΦΦΦΦ ΦΦ ΦΦ ♦· Φ· ·· * ·· ** *** |
15 | Überwurfmutter |
16 | spiralförmige Nut |
17 | Fixierstift |
18 | Ultraschall Markierung |
19 | Klebeverbindung |
20 | Klebeverbindung |
21 | Koppelstelle |
22 | Adapter |
23 | Knickschutz |
24 | Sterilüberzug |
25 | Schutzkappe |
26 | Öffnung |
27 | Befestigungselement |
28 | Markierungen |
29 | Fixierschraube |
30 | Klemmring |
31 | Nut |
Claims (25)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE20003349U DE20003349U1 (de) | 2000-02-24 | 2000-02-24 | Vorrichtung für die thermische Behandlung von biologischem Gewebe |
DE10008557A DE10008557A1 (de) | 2000-02-24 | 2000-02-24 | Vorrichtung zur thermischen Behandlung von biologischen Gewebe |
PCT/EP2001/002112 WO2001062171A1 (de) | 2000-02-24 | 2001-02-23 | Vorrichtung zur thermischen behandlung von biologischem gewebe |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE20003349U DE20003349U1 (de) | 2000-02-24 | 2000-02-24 | Vorrichtung für die thermische Behandlung von biologischem Gewebe |
DE10008557A DE10008557A1 (de) | 2000-02-24 | 2000-02-24 | Vorrichtung zur thermischen Behandlung von biologischen Gewebe |
Publications (1)
Publication Number | Publication Date |
---|---|
DE20003349U1 true DE20003349U1 (de) | 2000-06-08 |
Family
ID=26004499
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE20003349U Expired - Lifetime DE20003349U1 (de) | 2000-02-24 | 2000-02-24 | Vorrichtung für die thermische Behandlung von biologischem Gewebe |
DE10008557A Withdrawn DE10008557A1 (de) | 2000-02-24 | 2000-02-24 | Vorrichtung zur thermischen Behandlung von biologischen Gewebe |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE10008557A Withdrawn DE10008557A1 (de) | 2000-02-24 | 2000-02-24 | Vorrichtung zur thermischen Behandlung von biologischen Gewebe |
Country Status (2)
Country | Link |
---|---|
DE (2) | DE20003349U1 (de) |
WO (1) | WO2001062171A1 (de) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1929972A1 (de) * | 2006-12-05 | 2008-06-11 | I.A.L.T. S.c.r.l. | Ein Satz optischer Fasern zur perkutanen ablativen Behandlung |
WO2010028833A1 (de) * | 2008-09-11 | 2010-03-18 | Starmedtec Gmbh | Laser-handstück sowie verfahren zu seiner herstellung |
EP2672912A1 (de) * | 2011-02-07 | 2013-12-18 | Srinivasan, Pattanam | Fasereingebettete hohlnadel zur perkutanen verabreichung von laserenergie |
US9044594B2 (en) | 2010-02-21 | 2015-06-02 | C Laser, Inc. | Laser generator for deep tissue laser treatments using low intensity laser therapy causing selective destruction of nociceptive nerves |
US9149647B2 (en) | 2008-12-14 | 2015-10-06 | C Laser, Inc. | Method for deep tissue laser treatments using low intensity laser therapy causing selective destruction of Nociceptive nerves |
US9265576B2 (en) | 2010-02-21 | 2016-02-23 | C Laser, Inc. | Laser generator for medical treatment |
US10206742B2 (en) | 2010-02-21 | 2019-02-19 | C Laser, Inc. | Fiber embedded hollow spikes for percutaneous delivery of laser energy |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE202005017518U1 (de) * | 2005-11-04 | 2007-03-08 | Kämpfert, Marco | Stabendoskop |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2403063A1 (fr) * | 1977-09-15 | 1979-04-13 | Ki Gi | Instrument cryochirurgical |
US4693244A (en) * | 1984-05-22 | 1987-09-15 | Surgical Laser Technologies, Inc. | Medical and surgical laser probe I |
DE3813227A1 (de) * | 1987-05-25 | 1989-01-12 | Messerschmitt Boelkow Blohm | Einrichtung zur zirkumferenziellen bestrahlung von objekten |
US5169396A (en) * | 1990-06-08 | 1992-12-08 | Kambiz Dowlatshahi | Method for interstitial laser therapy |
DE4137983C2 (de) * | 1990-12-19 | 1997-03-06 | Schott Glaswerke | Applikationsvorrichtung für die Behandlung biologischer Gewebe mit Laserstrahlung |
WO1992017243A2 (en) * | 1991-04-05 | 1992-10-15 | Indigo Medical, Incorporated | Apparatus using a laser lucent needle |
DE4237286A1 (de) * | 1992-04-06 | 1994-05-05 | Laser Medizin Zentrum Ggmbh Be | Verfahren und Vorrichtung zur Effizienzsteigerung eines optischen Arbeitsschaftes zur Photo-Thermotherapie |
DE4211526A1 (de) * | 1992-04-06 | 1993-10-07 | Berlin Laser Medizin Zentrum | Optischer Arbeitsschaft zur Photo-Thermotherapie |
US5373571A (en) * | 1993-03-16 | 1994-12-13 | Spectran Specialty Optics Company | Fiber optic diffuser tip |
DE4403134A1 (de) * | 1993-05-14 | 1995-08-03 | Laser Medizin Zentrum Ggmbh Be | Kombinationsvorrichtung zur thermischen Verödung biologischen Gewebes |
US5383466A (en) * | 1993-05-14 | 1995-01-24 | Becton, Dickinson And Company | Instrument having enhanced ultrasound visibility |
AU725320B2 (en) * | 1994-09-09 | 2000-10-12 | Cardiofocus, Inc. | Phototherapeutic apparatus |
US6113589A (en) * | 1995-12-21 | 2000-09-05 | Laser Industries Ltd. | Fiber and a device incorporating the fiber therein for use in treating tissue volumes |
DE19614780C2 (de) * | 1996-04-04 | 2001-02-22 | Somatex Medizintechnische Inst | Laserapplikationsset |
DE19702898A1 (de) * | 1996-04-04 | 1998-07-23 | Somatex Medizintechnische Inst | Laser-Applikationskatheter |
DE19739456B4 (de) * | 1997-09-03 | 2008-01-03 | Trumpf Medizin Systeme Gmbh + Co. Kg | Applikationsvorrichtung für die Behandlung von Körpergewebe mittels Licht |
-
2000
- 2000-02-24 DE DE20003349U patent/DE20003349U1/de not_active Expired - Lifetime
- 2000-02-24 DE DE10008557A patent/DE10008557A1/de not_active Withdrawn
-
2001
- 2001-02-23 WO PCT/EP2001/002112 patent/WO2001062171A1/de active Application Filing
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1929972A1 (de) * | 2006-12-05 | 2008-06-11 | I.A.L.T. S.c.r.l. | Ein Satz optischer Fasern zur perkutanen ablativen Behandlung |
WO2008068789A1 (en) * | 2006-12-05 | 2008-06-12 | Elesta S.R.L. | A kit of optical fibers for percutaneous ablative treatment |
US8265446B2 (en) | 2006-12-05 | 2012-09-11 | Elesta S.R.L. | Kit of optical fibers for percutaneous ablative treatment |
WO2010028833A1 (de) * | 2008-09-11 | 2010-03-18 | Starmedtec Gmbh | Laser-handstück sowie verfahren zu seiner herstellung |
US9149647B2 (en) | 2008-12-14 | 2015-10-06 | C Laser, Inc. | Method for deep tissue laser treatments using low intensity laser therapy causing selective destruction of Nociceptive nerves |
US9693825B2 (en) | 2008-12-14 | 2017-07-04 | C Laser, Inc. | Fiber embedded hollow needle for percutaneous delivery of laser energy |
US9044594B2 (en) | 2010-02-21 | 2015-06-02 | C Laser, Inc. | Laser generator for deep tissue laser treatments using low intensity laser therapy causing selective destruction of nociceptive nerves |
US9265576B2 (en) | 2010-02-21 | 2016-02-23 | C Laser, Inc. | Laser generator for medical treatment |
US9782221B2 (en) | 2010-02-21 | 2017-10-10 | C Laser, Inc. | Treatment using low intensity laser therapy |
US10206742B2 (en) | 2010-02-21 | 2019-02-19 | C Laser, Inc. | Fiber embedded hollow spikes for percutaneous delivery of laser energy |
EP2672912A1 (de) * | 2011-02-07 | 2013-12-18 | Srinivasan, Pattanam | Fasereingebettete hohlnadel zur perkutanen verabreichung von laserenergie |
EP2672912A4 (de) * | 2011-02-07 | 2014-09-17 | Pattanam Srinivasan | Fasereingebettete hohlnadel zur perkutanen verabreichung von laserenergie |
Also Published As
Publication number | Publication date |
---|---|
DE10008557A1 (de) | 2001-10-25 |
WO2001062171A1 (de) | 2001-08-30 |
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