DE19975048I2 - 7- (3-disubstituted amino) phenyl pyrazolo 1,5-a-pyrimidine - Google Patents

7- (3-disubstituted amino) phenyl pyrazolo 1,5-a-pyrimidine

Info

Publication number
DE19975048I2
DE19975048I2 DE1999175048 DE19975048C DE19975048I2 DE 19975048 I2 DE19975048 I2 DE 19975048I2 DE 1999175048 DE1999175048 DE 1999175048 DE 19975048 C DE19975048 C DE 19975048C DE 19975048 I2 DE19975048 I2 DE 19975048I2
Authority
DE
Germany
Prior art keywords
alkyl
pyrimidine
disubstituted amino
dimethylformamide
reflux
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE1999175048
Other languages
German (de)
Inventor
John Paul Dusza
Andrew Stephen Tomcufcik
Jay Donald Albright
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/732,986 external-priority patent/US4626538A/en
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of DE19975048I2 publication Critical patent/DE19975048I2/en
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11B—INFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
    • G11B5/00—Recording by magnetisation or demagnetisation of a record carrier; Reproducing by magnetic means; Record carriers therefor
    • G11B5/48—Disposition or mounting of heads or head supports relative to record carriers ; arrangements of heads, e.g. for scanning the record carrier to increase the relative speed
    • G11B5/58—Disposition or mounting of heads or head supports relative to record carriers ; arrangements of heads, e.g. for scanning the record carrier to increase the relative speed with provision for moving the head for the purpose of maintaining alignment of the head relative to the record carrier during transducing operation, e.g. to compensate for surface irregularities of the latter or for track following
    • G11B5/584—Disposition or mounting of heads or head supports relative to record carriers ; arrangements of heads, e.g. for scanning the record carrier to increase the relative speed with provision for moving the head for the purpose of maintaining alignment of the head relative to the record carrier during transducing operation, e.g. to compensate for surface irregularities of the latter or for track following for track following on tapes
    • G11B5/588—Disposition or mounting of heads or head supports relative to record carriers ; arrangements of heads, e.g. for scanning the record carrier to increase the relative speed with provision for moving the head for the purpose of maintaining alignment of the head relative to the record carrier during transducing operation, e.g. to compensate for surface irregularities of the latter or for track following for track following on tapes by controlling the position of the rotating heads
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11B—INFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
    • G11B15/00—Driving, starting or stopping record carriers of filamentary or web form; Driving both such record carriers and heads; Guiding such record carriers or containers therefor; Control thereof; Control of operating function
    • G11B15/18—Driving; Starting; Stopping; Arrangements for control or regulation thereof
    • G11B15/1808—Driving of both record carrier and head
    • G11B15/1816—Programmed access in sequence to indexed parts of operating tapes cooperating with rotating heads
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11B—INFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
    • G11B15/00—Driving, starting or stopping record carriers of filamentary or web form; Driving both such record carriers and heads; Guiding such record carriers or containers therefor; Control thereof; Control of operating function
    • G11B15/18—Driving; Starting; Stopping; Arrangements for control or regulation thereof
    • G11B15/1808—Driving of both record carrier and head
    • G11B15/1825—Driving of both record carrier and head driving or moving the head in a direction which cuts across the direction of travel of the tape, e.g. for helicoïdal scanning
    • G11B15/1833—Driving of both record carrier and head driving or moving the head in a direction which cuts across the direction of travel of the tape, e.g. for helicoïdal scanning with head driven in a plane, cyclically around an axis, e.g. on headwheel
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11B—INFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
    • G11B15/00—Driving, starting or stopping record carriers of filamentary or web form; Driving both such record carriers and heads; Guiding such record carriers or containers therefor; Control thereof; Control of operating function
    • G11B15/18—Driving; Starting; Stopping; Arrangements for control or regulation thereof
    • G11B15/1808—Driving of both record carrier and head
    • G11B15/1875—Driving of both record carrier and head adaptations for special effects or editing
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11B—INFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
    • G11B5/00—Recording by magnetisation or demagnetisation of a record carrier; Reproducing by magnetic means; Record carriers therefor
    • G11B5/008—Recording on, or reproducing or erasing from, magnetic tapes, sheets, e.g. cards, or wires
    • G11B5/00813—Recording on, or reproducing or erasing from, magnetic tapes, sheets, e.g. cards, or wires magnetic tapes
    • G11B5/00817—Recording on, or reproducing or erasing from, magnetic tapes, sheets, e.g. cards, or wires magnetic tapes on longitudinal tracks only, e.g. for serpentine format recording
    • G11B5/00839—Recording on, or reproducing or erasing from, magnetic tapes, sheets, e.g. cards, or wires magnetic tapes on longitudinal tracks only, e.g. for serpentine format recording using cyclically driven heads providing segmented tracks

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDURE FOR PREPARING PYRAZOLE (1,5-A) PYRIMIDINES. IT INCLUDES: A) REACTING (II) WITH DIMETHYLFORMAMIDE DIMETHYLACETHOLE AT REFLUX, TO OBTAIN A (A); B) TREAT A (A) WITH SODIUM HYDRIDE IN DIMETHYLFORMAMIDE, TO GENERATE AN ANION; C) MAKE THE ANION REACT WITH FORMULA ALKYL HALIDE (R5X), TO GIVE A (III) AND D) TREAT (III) WITH (IV) IN GLACIAL ACETIC ACID AND REFLUX, TO OBTAIN A (I). BEING: (A), N- (3- (3-DIMETILAMINO) -1-OXO-2-PROPENIL) FENIL) ALCANAMIDA; R1, H, HAL OR CIANO; R2, H OR C 1 TO 4 ALKYL; R3, (V); R5, H, C 1A 6 ALKYL AND OTHERS; R6, ALKYL, C 1 TO 6, CYCLOALKYL FROM C 3 TO 6 AND OTHERS AND X, BR O I. ARE USED AS ANSIOLYTICS AND ANTISEPTICS. *FORMULA* (Machine-translation by Google Translate, not legally binding)
DE1999175048 1985-05-13 1986-04-21 7- (3-disubstituted amino) phenyl pyrazolo 1,5-a-pyrimidine Active DE19975048I2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/732,986 US4626538A (en) 1983-06-23 1985-05-13 [7-(3-disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidines

Publications (1)

Publication Number Publication Date
DE19975048I2 true DE19975048I2 (en) 2001-06-13

Family

ID=24945743

Family Applications (2)

Application Number Title Priority Date Filing Date
DE1999175048 Active DE19975048I2 (en) 1985-05-13 1986-04-21 7- (3-disubstituted amino) phenyl pyrazolo 1,5-a-pyrimidine
DE3689294T Expired - Lifetime DE3689294T2 (en) 1985-05-13 1986-04-21 [7- (3-disubstituted amino) phenyl] pyrazolo [1,5-a] pyrimidines.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE3689294T Expired - Lifetime DE3689294T2 (en) 1985-05-13 1986-04-21 [7- (3-disubstituted amino) phenyl] pyrazolo [1,5-a] pyrimidines.

Country Status (16)

Country Link
JP (1) JPH0784468B2 (en)
KR (1) KR900001887B1 (en)
AT (1) ATE97414T1 (en)
AU (1) AU587617B2 (en)
CA (1) CA1270825A (en)
DE (2) DE19975048I2 (en)
DK (1) DK170534B1 (en)
ES (1) ES8900165A1 (en)
FI (1) FI83324C (en)
HK (1) HK127795A (en)
IE (1) IE61755B1 (en)
IL (1) IL78700A (en)
NZ (1) NZ216052A (en)
PH (1) PH24037A (en)
SG (1) SG30590G (en)
ZA (1) ZA863499B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1198824C (en) * 1999-09-02 2005-04-27 纽罗克里恩生物科学有限公司 Polymorphs of N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-alpha]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
DE10004790B4 (en) * 2000-02-01 2004-09-09 Lts Lohmann Therapie-Systeme Ag Method for producing sewn or embroidered three-dimensional textile structure utilized for e.g. table cloth, involves connecting points on lattice structure with threads to form thread arrangement under which lattice structure is not visible
ES2222813B1 (en) * 2003-07-24 2005-12-16 Ferrer Internacional, S.A. N- (3- (3-SUBSTITUTES-PIRAZOLO (1,5-A) PIRIMIDIN-7-IL) -PENYL) -SULPHONAMIDS AND RELATED COMPOSITIONS AND METHODS

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4178449A (en) * 1978-04-17 1979-12-11 American Cyanamid Company Pyrazolo[1,5-a]pyrimidines and imidazo-[1,5-a]pyrimidines
NZ208554A (en) * 1983-06-23 1987-06-30 American Cyanamid Co (aryl and heteroaryl)-(7-(aryl and heteroaryl)-pyrazolo (1,5-a) pyrimidin-3-yl)-methanone derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
PH24037A (en) 1990-02-09
NZ216052A (en) 1989-04-26
SG30590G (en) 1995-09-18
FI83324B (en) 1991-03-15
IL78700A (en) 1989-06-30
JPS61260083A (en) 1986-11-18
IE61755B1 (en) 1994-11-30
CA1270825A (en) 1990-06-26
FI83324C (en) 1991-06-25
JPH0784468B2 (en) 1995-09-13
IL78700A0 (en) 1986-08-31
KR860009017A (en) 1986-12-19
ES8900165A1 (en) 1989-03-01
AU587617B2 (en) 1989-08-24
ES554887A0 (en) 1989-03-01
DK170534B1 (en) 1995-10-16
KR900001887B1 (en) 1990-03-26
FI861973A (en) 1986-11-14
DK218286D0 (en) 1986-05-12
DK218286A (en) 1986-11-14
AU5736086A (en) 1986-11-20
ATE97414T1 (en) 1993-12-15
HK127795A (en) 1995-08-18
IE861247L (en) 1986-11-13
ZA863499B (en) 1987-11-12
DE3689294D1 (en) 1993-12-23
FI861973A0 (en) 1986-05-12
DE3689294T2 (en) 1994-06-09

Similar Documents

Publication Publication Date Title
DE69028136D1 (en) Alkoxyiminoacetamide derivatives and their use as antifungal agents
EA199900953A1 (en) SUBSTITUTED PYRAZOLES AS AN INHIBITORS p38 KINASE
EG15458A (en) Improvements in or relating to 3-aryloxy-3-phenylpropylamines
DE69529121D1 (en) Use of CRF antagonists
NZ233735A (en) Heterocyclic substituted aminophenol derivatives
FI74002B (en) FOERFARANDE FOER FRAMSTAELLNING AV - KARBOLINDERIVAT.
ES2007177A6 (en) 1-(6-amino-9-purinyl)- beta -D-ribofuranuronic acid amides and thioamides
ES8505927A1 (en) Intermediates for the preparation of 1-(phenyl)-1-hydroxy-2-amino-3-fluoro propane derivatives.
DE19975048I2 (en) 7- (3-disubstituted amino) phenyl pyrazolo 1,5-a-pyrimidine
DE59404557D1 (en) Hetero-tricyclic-substituted phenyl-cyclohexane-carboxylic acid derivatives
ES8505947A1 (en) Preparation of 1-substituted azetidin-3-ol and acid halid thereof.
ATE138066T1 (en) PREPARATION OF 5,7-DIHYDROXY-1,2,4-TRIAZOLO(1,5- A>PYRIMIDINE-2-SULFONANILIDES
ES2009463A6 (en) New 2-propanol derivatives, their preparation and their application as medicaments
SU1297421A1 (en) HYDROCHLORIDES OF 3-SUBSTITUTED 2-ETHYL-4-METHYLPYRAZOLO (1,5-a) -BENZIMIDAZOLE, HAVING ANTIARRHTHMIC ACTIVITY
ES8205773A1 (en) Procedure for the obtaining of 2 (1H) -piridinones (Machine-translation by Google Translate, not legally binding)
ES8600206A1 (en) Procedure for the preparation of derived alkylenodiamines (Machine-translation by Google Translate, not legally binding)

Legal Events

Date Code Title Description
8364 No opposition during term of opposition