DE1103520B - Process for making a laxative - Google Patents

Process for making a laxative

Info

Publication number
DE1103520B
DE1103520B DEM42424A DEM0042424A DE1103520B DE 1103520 B DE1103520 B DE 1103520B DE M42424 A DEM42424 A DE M42424A DE M0042424 A DEM0042424 A DE M0042424A DE 1103520 B DE1103520 B DE 1103520B
Authority
DE
Germany
Prior art keywords
laxative
seeds
plantago
water
making
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DEM42424A
Other languages
German (de)
Inventor
Dr Rolf Madaus
Dr Alfred Kuhn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Madaus Holding GmbH
Original Assignee
Dr Madaus GmbH and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Madaus GmbH and Co filed Critical Dr Madaus GmbH and Co
Priority to DEM42424A priority Critical patent/DE1103520B/en
Priority to FR835556A priority patent/FR120M/en
Publication of DE1103520B publication Critical patent/DE1103520B/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/68Plantaginaceae (Plantain Family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482Cassia, e.g. golden shower tree

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pretreatment Of Seeds And Plants (AREA)
  • Medicines Containing Plant Substances (AREA)

Description

Verfahren zur Herstellung eines Abführinitteis Die Erfindung betrifft ein Verfahren zur Herstellung eines Abführmittels. Es ist bekannt, Semen Psyllii und Semen Plantaginis lanceolata wegen ihres Schleimgehaltes als Abführmittel zu verwenden. Die Samen wirken dadurch als Laxans, daß sie bei Berührung mit Wasser einen Schleim abzusondern vermögen. Dieser Schleim tritt auch bei der Einführung in den Darm aus den Samen aus, quillt auf und erhöht damit die Peristaltik des Darmes. Es handelt sich also nicht um chemische Stoffe mit einer laxierenden Komponente wie die bekannten Anthrachinonabkömmlinge.Method of making a purging device The invention relates to a method of making a laxative. It is known to Semen Psyllii and Semen Plantaginis lanceolata as a laxative because of their mucus content use. The seeds act as a laxative in that they come into contact with water able to secrete a mucus. This mucus also occurs upon introduction into the intestine from the seeds, swells and thus increases the peristalsis of the intestine. So it is not about chemical substances with a laxative component like the well-known anthraquinone derivatives.

Es gelingt, die Wirksamkeit der Erzeugnisse zu erhöhen, wenn man die Samen mahlt. Diese Wirkungssteigerung ist darauf zurückzuführen, daß die feinkörnigen Samenteile den Schleim vollständiger als die unzerkleinerten abgeben und schneller aufquellen. It is possible to increase the effectiveness of the product if one grinds the seeds. This increase in effectiveness is due to the fact that the fine-grained Seed parts release the mucus more completely than the uncomminuted ones and more quickly swell up.

Es wurde nun gefunden, daß man noch zu stärker wirksamen Präparaten gelangt, wenn man wie folgt vorgeht: Die Samen werden feinst gemahlen und mit Wasser versetzt, wobei durch Quellung ein dicker Brei entsteht, der durch an sich bekannte Vorrichtungen, z. B. einem Fleischwolf, in Strangform gebracht und im Vakuum bei mäßiger Wärme getrocknet wird, worauf das Präparat geschrotet und durch Sieben auf eine geeignete Korngröße gebracht wird. Hierbei entstehen naturgemäß auch besonders feine Anteile, die nach einem wesentlichen Merkmal der Erfindung nunmehr unter leichtem Anfeuchten mit wenig Wasser auf das gröbere, beim Schroten anfallende Korn mittels Dragieren aufgetragen werden. It has now been found that even more effective preparations can be achieved if you proceed as follows: The seeds are finely ground and mixed with water offset, whereby a thick pulp is created by swelling, which is known per se Devices, e.g. B. a meat grinder, brought into strand form and in a vacuum moderate heat is dried, whereupon the preparation is crushed and sieved a suitable grain size is brought. Naturally, this also creates special fine fractions, which, according to an essential feature of the invention, are now slightly Moisten with a little water on the coarser grain that occurs during the grinding process Dragging can be applied.

Der Anteil an diesen feinen Siebbestandteilen kann, wenn nötig, willkürlich erhöht werden, um den im folgenden beschriebenen Effekt noch zu verstärken. The proportion of these fine sieve components can, if necessary, be arbitrary can be increased in order to intensify the effect described below.

Ein so vorbereitetes Korn zeigt nicht nur eine schnellere Quellungsgeschwindigkeit, sondern auch eine Erhöhung des gesamten Quellvolumens.A grain prepared in this way not only shows a faster swelling rate, but also an increase in the total swell volume.

Gewöhnlich werden Dragees unter Verwendung von Zucker hergestellt. Da Zucker in Laxantien, insbesondere in Granulat- bzw. Dragéeform nicht immer erwünscht ist, besonders bei Verwendung des Laxans während Abmagerungskuren oder durch Diabetiker, wird das Dragieren zweckmäßig unter Verwendung von Mannit vorgenommen. Dies hat sich auch deswegen als zweckmäßig erwiesen, als die Plantagosamen keine Reservestärke enthalten und damit die Anwendung der Plantagosamen für Abführtabletten beim Diabetiker besonders geeignet ist. Dragees are usually made using sugar. Since sugar in laxatives, especially in granulate or dragee form, is not always desirable especially when using the laxative during weight loss cures or by diabetics, the coating is expediently carried out using mannitol. this has This is also why it has proven to be useful, as the plantago seeds do not have any reserve strength and thus the use of the plantago seeds for purging tablets for diabetics is particularly suitable.

Als besonders zweckmäßig hat sich die Verwendung von Plantago ovata erwiesen. The use of Plantago ovata has proven to be particularly useful proven.

Claims (1)

PATENTANSPRUCH: Verfahren zur Herstellung eines Abführmittels aus Plantago-Arten, dadurch gekcnnzeidinct, daß man Plantagosamen, vorzugsweise Semen Plantaginis ovatae, mahlt, mit Wasser anteigt, den dabei entstehenden hochviskosen Brei durch an sich bekannte Vorrichtungen in Strangform bringt und anschließend trocknet, hierauf die Masse durch Schroten zerkleinert und zu zwei Fraktionen siebt, deren feinere mit Korngrößen unter 1 mm nach Anteigen mit wenig Wasser zum Dragieren der groberen Fraktion verwendet. PATENT CLAIM: Process for the production of a laxative from Plantago species, characterized by the fact that plantago seeds, preferably semen Plantaginis ovatae, grinds, pastes with water, the resulting highly viscous Brings pulp into strand form by means known per se and then dries, then the mass is crushed by grinding and sifted into two fractions, the finer ones with grain sizes below 1 mm after pasting with a little water for coating the coarser fraction used.
DEM42424A 1959-08-12 1959-08-12 Process for making a laxative Pending DE1103520B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DEM42424A DE1103520B (en) 1959-08-12 1959-08-12 Process for making a laxative
FR835556A FR120M (en) 1959-08-12 1960-08-10 New laxative composition.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEM42424A DE1103520B (en) 1959-08-12 1959-08-12 Process for making a laxative

Publications (1)

Publication Number Publication Date
DE1103520B true DE1103520B (en) 1961-03-30

Family

ID=7304334

Family Applications (1)

Application Number Title Priority Date Filing Date
DEM42424A Pending DE1103520B (en) 1959-08-12 1959-08-12 Process for making a laxative

Country Status (2)

Country Link
DE (1) DE1103520B (en)
FR (1) FR120M (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2473311A1 (en) * 1980-01-16 1981-07-17 Madaus & Co Dr LAXATIVE BASED ON PLANTAGO SEEDS AND SENSE FRUITS AND PROCESS FOR ITS PREPARATION
DE202007007143U1 (en) 2007-05-02 2008-06-12 Madaus Gmbh New pharmaceutical composition for use as a laxative
DE102007023397A1 (en) 2007-05-02 2008-11-06 Madaus Gmbh New pharmaceutical composition for use as a laxative

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2919449C2 (en) * 1979-05-15 1981-08-06 Kowalsky, Horst, Dr.med., 5000 Köln Dietary agent for natural digestive regulation
US4511561A (en) * 1980-01-16 1985-04-16 Dr. Madaus & Co. Laxative composition comprising psyllium seeds and senna fruits

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2473311A1 (en) * 1980-01-16 1981-07-17 Madaus & Co Dr LAXATIVE BASED ON PLANTAGO SEEDS AND SENSE FRUITS AND PROCESS FOR ITS PREPARATION
DE202007007143U1 (en) 2007-05-02 2008-06-12 Madaus Gmbh New pharmaceutical composition for use as a laxative
DE102007023397A1 (en) 2007-05-02 2008-11-06 Madaus Gmbh New pharmaceutical composition for use as a laxative
WO2008135115A2 (en) 2007-05-02 2008-11-13 Madaus Gmbh Novel pharmaceutical composition for use as a laxative
EP2139505A2 (en) 2007-05-02 2010-01-06 Madaus GmbH Novel pharmaceutical composition for use as a laxative

Also Published As

Publication number Publication date
FR120M (en) 1961-01-09

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