DE1103520B - Process for making a laxative - Google Patents
Process for making a laxativeInfo
- Publication number
- DE1103520B DE1103520B DEM42424A DEM0042424A DE1103520B DE 1103520 B DE1103520 B DE 1103520B DE M42424 A DEM42424 A DE M42424A DE M0042424 A DEM0042424 A DE M0042424A DE 1103520 B DE1103520 B DE 1103520B
- Authority
- DE
- Germany
- Prior art keywords
- laxative
- seeds
- plantago
- water
- making
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008141 laxative Substances 0.000 title claims description 8
- 230000002475 laxative effect Effects 0.000 title claims description 7
- 238000000034 method Methods 0.000 title claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- 241001127637 Plantago Species 0.000 claims description 4
- 238000004519 manufacturing process Methods 0.000 claims description 3
- 210000000582 semen Anatomy 0.000 claims description 3
- 239000011248 coating agent Substances 0.000 claims description 2
- 238000000576 coating method Methods 0.000 claims description 2
- 238000000227 grinding Methods 0.000 claims description 2
- 210000003097 mucus Anatomy 0.000 description 4
- 239000008298 dragée Substances 0.000 description 2
- 210000000936 intestine Anatomy 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 238000010926 purge Methods 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- 241001098499 Lanceolata Species 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- 244000134552 Plantago ovata Species 0.000 description 1
- 235000003421 Plantago ovata Nutrition 0.000 description 1
- PYKYMHQGRFAEBM-UHFFFAOYSA-N anthraquinone Natural products CCC(=O)c1c(O)c2C(=O)C3C(C=CC=C3O)C(=O)c2cc1CC(=O)OC PYKYMHQGRFAEBM-UHFFFAOYSA-N 0.000 description 1
- 150000004056 anthraquinones Chemical class 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 229940125722 laxative agent Drugs 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 230000008855 peristalsis Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000004580 weight loss Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/68—Plantaginaceae (Plantain Family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pretreatment Of Seeds And Plants (AREA)
- Medicines Containing Plant Substances (AREA)
Description
Verfahren zur Herstellung eines Abführinitteis Die Erfindung betrifft ein Verfahren zur Herstellung eines Abführmittels. Es ist bekannt, Semen Psyllii und Semen Plantaginis lanceolata wegen ihres Schleimgehaltes als Abführmittel zu verwenden. Die Samen wirken dadurch als Laxans, daß sie bei Berührung mit Wasser einen Schleim abzusondern vermögen. Dieser Schleim tritt auch bei der Einführung in den Darm aus den Samen aus, quillt auf und erhöht damit die Peristaltik des Darmes. Es handelt sich also nicht um chemische Stoffe mit einer laxierenden Komponente wie die bekannten Anthrachinonabkömmlinge.Method of making a purging device The invention relates to a method of making a laxative. It is known to Semen Psyllii and Semen Plantaginis lanceolata as a laxative because of their mucus content use. The seeds act as a laxative in that they come into contact with water able to secrete a mucus. This mucus also occurs upon introduction into the intestine from the seeds, swells and thus increases the peristalsis of the intestine. So it is not about chemical substances with a laxative component like the well-known anthraquinone derivatives.
Es gelingt, die Wirksamkeit der Erzeugnisse zu erhöhen, wenn man die Samen mahlt. Diese Wirkungssteigerung ist darauf zurückzuführen, daß die feinkörnigen Samenteile den Schleim vollständiger als die unzerkleinerten abgeben und schneller aufquellen. It is possible to increase the effectiveness of the product if one grinds the seeds. This increase in effectiveness is due to the fact that the fine-grained Seed parts release the mucus more completely than the uncomminuted ones and more quickly swell up.
Es wurde nun gefunden, daß man noch zu stärker wirksamen Präparaten gelangt, wenn man wie folgt vorgeht: Die Samen werden feinst gemahlen und mit Wasser versetzt, wobei durch Quellung ein dicker Brei entsteht, der durch an sich bekannte Vorrichtungen, z. B. einem Fleischwolf, in Strangform gebracht und im Vakuum bei mäßiger Wärme getrocknet wird, worauf das Präparat geschrotet und durch Sieben auf eine geeignete Korngröße gebracht wird. Hierbei entstehen naturgemäß auch besonders feine Anteile, die nach einem wesentlichen Merkmal der Erfindung nunmehr unter leichtem Anfeuchten mit wenig Wasser auf das gröbere, beim Schroten anfallende Korn mittels Dragieren aufgetragen werden. It has now been found that even more effective preparations can be achieved if you proceed as follows: The seeds are finely ground and mixed with water offset, whereby a thick pulp is created by swelling, which is known per se Devices, e.g. B. a meat grinder, brought into strand form and in a vacuum moderate heat is dried, whereupon the preparation is crushed and sieved a suitable grain size is brought. Naturally, this also creates special fine fractions, which, according to an essential feature of the invention, are now slightly Moisten with a little water on the coarser grain that occurs during the grinding process Dragging can be applied.
Der Anteil an diesen feinen Siebbestandteilen kann, wenn nötig, willkürlich erhöht werden, um den im folgenden beschriebenen Effekt noch zu verstärken. The proportion of these fine sieve components can, if necessary, be arbitrary can be increased in order to intensify the effect described below.
Ein so vorbereitetes Korn zeigt nicht nur eine schnellere Quellungsgeschwindigkeit, sondern auch eine Erhöhung des gesamten Quellvolumens.A grain prepared in this way not only shows a faster swelling rate, but also an increase in the total swell volume.
Gewöhnlich werden Dragees unter Verwendung von Zucker hergestellt. Da Zucker in Laxantien, insbesondere in Granulat- bzw. Dragéeform nicht immer erwünscht ist, besonders bei Verwendung des Laxans während Abmagerungskuren oder durch Diabetiker, wird das Dragieren zweckmäßig unter Verwendung von Mannit vorgenommen. Dies hat sich auch deswegen als zweckmäßig erwiesen, als die Plantagosamen keine Reservestärke enthalten und damit die Anwendung der Plantagosamen für Abführtabletten beim Diabetiker besonders geeignet ist. Dragees are usually made using sugar. Since sugar in laxatives, especially in granulate or dragee form, is not always desirable especially when using the laxative during weight loss cures or by diabetics, the coating is expediently carried out using mannitol. this has This is also why it has proven to be useful, as the plantago seeds do not have any reserve strength and thus the use of the plantago seeds for purging tablets for diabetics is particularly suitable.
Als besonders zweckmäßig hat sich die Verwendung von Plantago ovata erwiesen. The use of Plantago ovata has proven to be particularly useful proven.
Claims (1)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEM42424A DE1103520B (en) | 1959-08-12 | 1959-08-12 | Process for making a laxative |
FR835556A FR120M (en) | 1959-08-12 | 1960-08-10 | New laxative composition. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEM42424A DE1103520B (en) | 1959-08-12 | 1959-08-12 | Process for making a laxative |
Publications (1)
Publication Number | Publication Date |
---|---|
DE1103520B true DE1103520B (en) | 1961-03-30 |
Family
ID=7304334
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DEM42424A Pending DE1103520B (en) | 1959-08-12 | 1959-08-12 | Process for making a laxative |
Country Status (2)
Country | Link |
---|---|
DE (1) | DE1103520B (en) |
FR (1) | FR120M (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2473311A1 (en) * | 1980-01-16 | 1981-07-17 | Madaus & Co Dr | LAXATIVE BASED ON PLANTAGO SEEDS AND SENSE FRUITS AND PROCESS FOR ITS PREPARATION |
DE202007007143U1 (en) | 2007-05-02 | 2008-06-12 | Madaus Gmbh | New pharmaceutical composition for use as a laxative |
DE102007023397A1 (en) | 2007-05-02 | 2008-11-06 | Madaus Gmbh | New pharmaceutical composition for use as a laxative |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2919449C2 (en) * | 1979-05-15 | 1981-08-06 | Kowalsky, Horst, Dr.med., 5000 Köln | Dietary agent for natural digestive regulation |
US4511561A (en) * | 1980-01-16 | 1985-04-16 | Dr. Madaus & Co. | Laxative composition comprising psyllium seeds and senna fruits |
-
1959
- 1959-08-12 DE DEM42424A patent/DE1103520B/en active Pending
-
1960
- 1960-08-10 FR FR835556A patent/FR120M/en active Active
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2473311A1 (en) * | 1980-01-16 | 1981-07-17 | Madaus & Co Dr | LAXATIVE BASED ON PLANTAGO SEEDS AND SENSE FRUITS AND PROCESS FOR ITS PREPARATION |
DE202007007143U1 (en) | 2007-05-02 | 2008-06-12 | Madaus Gmbh | New pharmaceutical composition for use as a laxative |
DE102007023397A1 (en) | 2007-05-02 | 2008-11-06 | Madaus Gmbh | New pharmaceutical composition for use as a laxative |
WO2008135115A2 (en) | 2007-05-02 | 2008-11-13 | Madaus Gmbh | Novel pharmaceutical composition for use as a laxative |
EP2139505A2 (en) | 2007-05-02 | 2010-01-06 | Madaus GmbH | Novel pharmaceutical composition for use as a laxative |
Also Published As
Publication number | Publication date |
---|---|
FR120M (en) | 1961-01-09 |
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