DD123322A5 - - Google Patents

Info

Publication number
DD123322A5
DD123322A5 DD188797A DD18879775A DD123322A5 DD 123322 A5 DD123322 A5 DD 123322A5 DD 188797 A DD188797 A DD 188797A DD 18879775 A DD18879775 A DD 18879775A DD 123322 A5 DD123322 A5 DD 123322A5
Authority
DD
German Democratic Republic
Application number
DD188797A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of DD123322A5 publication Critical patent/DD123322A5/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom
    • C07C279/26—X and Y being nitrogen atoms, i.e. biguanides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DD188797A 1974-10-11 1975-10-10 DD123322A5 (xx)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1369774A CH602612A5 (xx) 1974-10-11 1974-10-11

Publications (1)

Publication Number Publication Date
DD123322A5 true DD123322A5 (xx) 1976-12-12

Family

ID=4394567

Family Applications (1)

Application Number Title Priority Date Filing Date
DD188797A DD123322A5 (xx) 1974-10-11 1975-10-10

Country Status (26)

Country Link
US (1) US4028402A (xx)
JP (1) JPS51125718A (xx)
AR (1) AR209457A1 (xx)
AT (1) AT343676B (xx)
BE (1) BE834369A (xx)
BR (1) BR7506595A (xx)
CA (1) CA1053258A (xx)
CH (1) CH602612A5 (xx)
CU (1) CU34371A (xx)
DD (1) DD123322A5 (xx)
DE (1) DE2542598A1 (xx)
DK (1) DK140834B (xx)
ES (1) ES441673A1 (xx)
FI (1) FI752626A (xx)
FR (1) FR2287221A1 (xx)
GB (1) GB1473256A (xx)
IE (1) IE41807B1 (xx)
IL (1) IL48116A (xx)
LU (1) LU73557A1 (xx)
NL (1) NL7511890A (xx)
NO (1) NO753447L (xx)
PH (1) PH12279A (xx)
PL (1) PL95259B1 (xx)
SE (1) SE7511357L (xx)
SU (1) SU572200A3 (xx)
ZA (1) ZA755861B (xx)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2401898A1 (fr) * 1977-09-05 1979-03-30 Aec Chim Organ Biolog Nouveau sel de l'acide patoique
DE19616486C5 (de) 1996-04-25 2016-06-30 Royalty Pharma Collection Trust Verfahren zur Senkung des Blutglukosespiegels in Säugern
US20020006899A1 (en) * 1998-10-06 2002-01-17 Pospisilik Andrew J. Use of dipeptidyl peptidase IV effectors for lowering blood pressure in mammals
EP1004304A4 (en) 1996-12-24 2002-10-16 Sumitomo Pharma COMPOSITION WITH ACORBIC ACID
DE19823831A1 (de) * 1998-05-28 1999-12-02 Probiodrug Ges Fuer Arzneim Neue pharmazeutische Verwendung von Isoleucyl Thiazolidid und seinen Salzen
DE19828113A1 (de) 1998-06-24 2000-01-05 Probiodrug Ges Fuer Arzneim Prodrugs von Inhibitoren der Dipeptidyl Peptidase IV
DE19828114A1 (de) 1998-06-24 2000-01-27 Probiodrug Ges Fuer Arzneim Produgs instabiler Inhibitoren der Dipeptidyl Peptidase IV
DE19834591A1 (de) 1998-07-31 2000-02-03 Probiodrug Ges Fuer Arzneim Verfahren zur Steigerung des Blutglukosespiegels in Säugern
US20030176357A1 (en) * 1998-10-06 2003-09-18 Pospisilik Andrew J. Dipeptidyl peptidase IV inhibitors and their uses for lowering blood pressure levels
DE19926233C1 (de) 1999-06-10 2000-10-19 Probiodrug Ges Fuer Arzneim Verfahren zur Herstellung von Thiazolidin
DE19940130A1 (de) * 1999-08-24 2001-03-01 Probiodrug Ges Fuer Arzneim Neue Effektoren der Dipeptidyl Peptidase IV zur topischen Anwendung
CN1287779C (zh) 1999-10-06 2006-12-06 黑川清 羰基压迫降低剂
US20080076811A1 (en) * 2000-01-21 2008-03-27 Bork Balkan Combinations comprising depeptidypeptidase-iv inhibitors and antidiabetic agents
PT1283735E (pt) * 2000-03-31 2009-03-19 Prosidion Ltd Processo para melhoramento da sinalização de ilhéus na diabetes mellitus e para a sua prevenção
FR2809310B1 (fr) 2000-05-26 2004-02-13 Centre Nat Rech Scient Utilisation de derives de biguanide pour fabriquer un medicament ayant un effet cicatrisant
JP2005097117A (ja) * 2000-06-30 2005-04-14 Chugai Pharmaceut Co Ltd 糖尿病治療剤
US7132104B1 (en) 2000-10-27 2006-11-07 Probiodrug Ag Modulation of central nervous system (CNS) dipeptidyl peptidase IV (DPIV) -like activity for the treatment of neurological and neuropsychological disorders
AU2002227898A1 (en) * 2000-10-27 2002-05-06 Probiodrug Ag Method for the treatment of neurological and neuropsychological disorders
US6890905B2 (en) 2001-04-02 2005-05-10 Prosidion Limited Methods for improving islet signaling in diabetes mellitus and for its prevention
US20030130199A1 (en) * 2001-06-27 2003-07-10 Von Hoersten Stephan Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents
DE10150203A1 (de) 2001-10-12 2003-04-17 Probiodrug Ag Peptidylketone als Inhibitoren der DPIV
US7368421B2 (en) 2001-06-27 2008-05-06 Probiodrug Ag Use of dipeptidyl peptidase IV inhibitors in the treatment of multiple sclerosis
JP2005504766A (ja) * 2001-08-16 2005-02-17 プロバイオドラッグ アーゲー プロリンエンドペプチダーゼ阻害剤の、細胞内シグナルカスケード依存性イノシトール（１，４，５）トリホスフェート濃度調節への使用。
US6844316B2 (en) 2001-09-06 2005-01-18 Probiodrug Ag Inhibitors of dipeptidyl peptidase I
NZ534877A (en) 2002-02-28 2006-05-26 Prosidion Ltd Glutaminyl based DPIV inhibitors
US20030232761A1 (en) * 2002-03-28 2003-12-18 Hinke Simon A. Novel analogues of glucose-dependent insulinotropic polypeptide
US20040033051A1 (en) * 2002-08-16 2004-02-19 Ip Kiril Kun Wan Method and system for producing and displaying visual presentations which inhibit off-screen duplication
US20040058876A1 (en) * 2002-09-18 2004-03-25 Torsten Hoffmann Secondary binding site of dipeptidyl peptidase IV (DP IV)
EP1543023B1 (en) * 2002-09-18 2010-03-17 Prosidion Limited Secondary binding site of dipeptidyl peptidase iv (dp iv)
KR20060009902A (ko) 2003-05-05 2006-02-01 프로비오드룩 아게 글루타미닐 및 글루타메이트 사이클라제의 이펙터의 용도
DE602004026289D1 (de) 2003-05-05 2010-05-12 Probiodrug Ag Glutaminylcyclase-hemmer
US7462599B2 (en) * 2003-10-15 2008-12-09 Probiodrug Ag Use of effectors of glutaminyl and glutamate cyclases
US20100099721A1 (en) * 2003-11-03 2010-04-22 Probiodrug Ag Novel compounds for the treatment of neurological disorders
US20050171112A1 (en) * 2003-11-03 2005-08-04 Probiodrug Ag Combinations useful for the treatment of neuronal disorders
CA2554809C (en) 2004-02-05 2014-04-29 Probiodrug Ag Novel n-alkyl thiourea- and thioamide-substituted imidazolyl inhibitors of glutaminyl cyclase
KR100926417B1 (ko) 2007-01-29 2009-11-12 한올제약주식회사 Ｎ,ｎ―디메틸 이미도디카르본이미딕 디아미드의 초산염,그의 제조방법 및 그를 포함하는 약제학적 조성물
WO2008097861A2 (en) * 2007-02-02 2008-08-14 Braincells, Inc. MODULATION OF NEUROGENESIS WITH BIGUANIDES AND GSK3-ß AGENTS
JP5292404B2 (ja) * 2007-09-21 2013-09-18 ハンオル バイオファーマ カンパニー，リミテッド Ｎ，ｎ−ジメチルイミドジカルボンイミド酸ジアミドのジカルボン酸塩、その製造方法、及びその薬剤学的組成物
KR101104912B1 (ko) 2008-01-08 2012-01-12 한올바이오파마주식회사 Ｎ,ｎ―디메틸 이미도디카르본이미딕 디아미드의 니코틴산염, 그의 제조방법 및 그를 포함하는 약제학적 조성물
BRPI0822909B8 (pt) * 2008-06-26 2021-05-25 Laboratorios Silanes S A De C V sal de glicinato de metformina para o controle da glicose sanguínea
US20110021634A1 (en) 2009-06-18 2011-01-27 Patel Pranav Dushyant Processes for preparing metformin hydrochloride
WO2011049400A2 (ko) * 2009-10-23 2011-04-28 한올바이오파마주식회사 N,n-디메틸 이미도디카르본이미딕 디아미드의 산 부가염을 포함하는 항암용 약제학적 조성물
KR101324283B1 (ko) 2010-04-27 2013-11-01 한올바이오파마주식회사 바이구아나이드 화합물의 신규 염, 그의 제조방법, 그를 포함하는 약제학적 조성물
MX2019003725A (es) 2016-09-30 2019-08-12 Laboratorios Silanes S A De C V Glicinato de metformina, composiciones farmaceuticas que comprenden la misma, y metodos de uso de la misma.
US11510886B2 (en) 2016-09-30 2022-11-29 Laboratorios Silanes, S.A. De C.V. Metformin amino acid compounds and methods of using the same
CN106986791A (zh) * 2017-05-11 2017-07-28 杜剑平 一种***的药物化合物及其制备方法和应用
CN107118130A (zh) * 2017-05-11 2017-09-01 杜剑平 一类***的药物化合物及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3179562A (en) * 1961-08-23 1965-04-20 Du Pont Treatment of diabetes with alpha, alpha substituted acetic acid derivatives

Also Published As

Publication number Publication date
DK140834C (xx) 1980-04-28
SE7511357L (sv) 1976-04-12
PL95259B1 (pl) 1977-10-31
IL48116A (en) 1979-07-25
CU34371A (es) 1979-06-01
DK457475A (xx) 1976-04-12
SU572200A3 (ru) 1977-09-05
LU73557A1 (xx) 1977-05-24
BE834369A (fr) 1976-04-12
CH602612A5 (xx) 1978-07-31
ZA755861B (en) 1976-08-25
BR7506595A (pt) 1976-08-17
FI752626A (xx) 1976-04-12
AT343676B (de) 1978-06-12
NO753447L (xx) 1976-04-13
JPS51125718A (en) 1976-11-02
IE41807B1 (en) 1980-03-26
IE41807L (en) 1976-04-11
AR209457A1 (es) 1977-04-29
DK140834B (da) 1979-11-26
US4028402A (en) 1977-06-07
ATA776375A (de) 1977-10-15
CA1053258A (en) 1979-04-24
GB1473256A (en) 1977-05-11
NL7511890A (nl) 1976-04-13
AU8497775A (en) 1977-03-24
FR2287221A1 (fr) 1976-05-07
DE2542598A1 (de) 1976-04-22
ES441673A1 (es) 1977-04-01
IL48116A0 (en) 1975-11-25
PH12279A (en) 1978-12-12

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