CZ347597A3 - Estery karbapenemových sloučenin a farmaceutický prostředek s jejich obsahem - Google Patents

Estery karbapenemových sloučenin a farmaceutický prostředek s jejich obsahem Download PDF

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Publication number
CZ347597A3
CZ347597A3 CZ973475A CZ347597A CZ347597A3 CZ 347597 A3 CZ347597 A3 CZ 347597A3 CZ 973475 A CZ973475 A CZ 973475A CZ 347597 A CZ347597 A CZ 347597A CZ 347597 A3 CZ347597 A3 CZ 347597A3
Authority
CZ
Czechia
Prior art keywords
compound
ethyl
methyl
formula
mixture
Prior art date
Application number
CZ973475A
Other languages
Czech (cs)
English (en)
Inventor
George Burton
Stephen Frederick Moss
Alfred John Eglington
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9508957.9A external-priority patent/GB9508957D0/en
Priority claimed from GBGB9508955.3A external-priority patent/GB9508955D0/en
Priority claimed from GBGB9508956.1A external-priority patent/GB9508956D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of CZ347597A3 publication Critical patent/CZ347597A3/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/14—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/02—Preparation
    • C07D477/06—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C07D477/08—Modification of a carboxyl group directly attached in position 2, e.g. esterification
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CZ973475A 1995-05-03 1996-05-02 Estery karbapenemových sloučenin a farmaceutický prostředek s jejich obsahem CZ347597A3 (cs)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9508957.9A GB9508957D0 (en) 1995-05-03 1995-05-03 Novel compounds
GBGB9508955.3A GB9508955D0 (en) 1995-05-03 1995-05-03 Novel compounds
GBGB9508956.1A GB9508956D0 (en) 1995-05-03 1995-05-03 Novel compounds

Publications (1)

Publication Number Publication Date
CZ347597A3 true CZ347597A3 (cs) 1998-08-12

Family

ID=27267696

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ973475A CZ347597A3 (cs) 1995-05-03 1996-05-02 Estery karbapenemových sloučenin a farmaceutický prostředek s jejich obsahem

Country Status (22)

Country Link
EP (1) EP0823910A1 (tr)
JP (1) JPH11504910A (tr)
KR (1) KR19990008355A (tr)
CN (1) CN1185783A (tr)
AR (1) AR005416A1 (tr)
AU (1) AU5813996A (tr)
BG (1) BG102014A (tr)
BR (1) BR9608313A (tr)
CA (1) CA2217990A1 (tr)
CZ (1) CZ347597A3 (tr)
EA (1) EA199700293A1 (tr)
HU (1) HUP9801066A3 (tr)
IL (1) IL118092A0 (tr)
MA (1) MA23853A1 (tr)
MX (1) MX9708421A (tr)
NO (1) NO974994D0 (tr)
OA (1) OA10632A (tr)
PE (1) PE50697A1 (tr)
PL (1) PL323141A1 (tr)
SK (1) SK146497A3 (tr)
TR (1) TR199701286T1 (tr)
WO (1) WO1996034868A1 (tr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2902659A1 (fr) 2006-06-23 2007-12-28 Pierre Fabre Medicament Sa Ester de dha et son utilisation dans le traitement et la prevention des maladies cardiovasculaires
WO2013157583A1 (ja) * 2012-04-18 2013-10-24 大日本住友製薬株式会社 新規カルバペネム化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1593524A (en) * 1976-11-19 1981-07-15 Merck & Co Inc 1-carba-2-penem-3-carboxylic acids
CA1212105A (en) * 1980-04-30 1986-09-30 Shoji Ikeda Ampicillin esters and production thereof
AU7467194A (en) * 1993-08-18 1995-03-14 Sankyo Company Limited Crystalline carbapenem derivatives
WO1995011905A1 (en) * 1993-10-29 1995-05-04 Smithkline Beecham Plc 2-(pyrazol-3-yl)carbapenem derivatives

Also Published As

Publication number Publication date
PE50697A1 (es) 1997-12-18
WO1996034868A1 (en) 1996-11-07
EA199700293A1 (ru) 1998-06-25
OA10632A (en) 2002-09-16
MX9708421A (es) 1998-02-28
MA23853A1 (fr) 1996-12-31
BR9608313A (pt) 1999-01-26
BG102014A (en) 1998-11-30
TR199701286T1 (tr) 1998-02-21
PL323141A1 (en) 1998-03-16
EP0823910A1 (en) 1998-02-18
JPH11504910A (ja) 1999-05-11
KR19990008355A (ko) 1999-01-25
SK146497A3 (en) 1998-05-06
NO974994L (no) 1997-10-30
CN1185783A (zh) 1998-06-24
AU5813996A (en) 1996-11-21
NO974994D0 (no) 1997-10-30
IL118092A0 (en) 1996-09-12
HUP9801066A2 (hu) 1998-08-28
HUP9801066A3 (en) 1999-01-28
AR005416A1 (es) 1999-06-23
CA2217990A1 (en) 1996-11-07

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Legal Events

Date Code Title Description
PD00 Pending as of 2000-06-30 in czech republic