CY1122480T1 - Μεθυλικη βαρδοξολονη για τη θεραπεια παχυσαρκιας - Google Patents
Μεθυλικη βαρδοξολονη για τη θεραπεια παχυσαρκιαςInfo
- Publication number
- CY1122480T1 CY1122480T1 CY20201100022T CY201100022T CY1122480T1 CY 1122480 T1 CY1122480 T1 CY 1122480T1 CY 20201100022 T CY20201100022 T CY 20201100022T CY 201100022 T CY201100022 T CY 201100022T CY 1122480 T1 CY1122480 T1 CY 1122480T1
- Authority
- CY
- Cyprus
- Prior art keywords
- methyl
- obesity
- vardoxolone
- treatment
- administration
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Abstract
Η παρούσα εφεύρεση αφορά σε μεθόδους θεραπείας ή/και αποτροπής παχυσαρκίας που περιλαμβάνουν τη χορήγηση αντιοξειδωτικών ρυθμιστών φλεγμονής που περιγράφονται στο παρόν, που συμπεριλαμβάνουν για παράδειγμα μεθυλική βαρδοξολόνη.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32327610P | 2010-04-12 | 2010-04-12 | |
US38909010P | 2010-10-01 | 2010-10-01 | |
PCT/US2011/032156 WO2011130302A2 (en) | 2010-04-12 | 2011-04-12 | Method of treating obesity using antioxidant inflammation modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1122480T1 true CY1122480T1 (el) | 2021-01-27 |
Family
ID=44259866
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20201100022T CY1122480T1 (el) | 2010-04-12 | 2020-01-09 | Μεθυλικη βαρδοξολονη για τη θεραπεια παχυσαρκιας |
Country Status (29)
Country | Link |
---|---|
US (2) | US10105372B2 (el) |
EP (1) | EP2558105B1 (el) |
JP (1) | JP5990160B2 (el) |
KR (1) | KR101819699B1 (el) |
CN (1) | CN102939089B (el) |
AU (1) | AU2011240690C1 (el) |
BR (1) | BR112012026112B1 (el) |
CA (1) | CA2795320C (el) |
CL (1) | CL2012002859A1 (el) |
CY (1) | CY1122480T1 (el) |
DK (1) | DK2558105T3 (el) |
EA (1) | EA026567B1 (el) |
ES (1) | ES2768204T3 (el) |
HR (1) | HRP20192291T1 (el) |
HU (1) | HUE047994T2 (el) |
IL (1) | IL222273B (el) |
LT (1) | LT2558105T (el) |
ME (1) | ME03713B (el) |
MX (1) | MX357596B (el) |
MY (1) | MY163031A (el) |
NZ (1) | NZ602826A (el) |
PL (1) | PL2558105T3 (el) |
PT (1) | PT2558105T (el) |
RS (1) | RS59850B1 (el) |
SG (2) | SG10201808661XA (el) |
SI (1) | SI2558105T1 (el) |
TW (1) | TWI558724B (el) |
WO (1) | WO2011130302A2 (el) |
ZA (1) | ZA201207518B (el) |
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US6326507B1 (en) | 1998-06-19 | 2001-12-04 | Trustees Of Dartmouth College | Therapeutic compounds and methods of use |
MX356760B (es) | 2008-01-11 | 2018-06-12 | Dartmouth College | Triterpenoides sinteticos y metodos de uso en el tratamiento de enfermedad. |
CN102066397B (zh) | 2008-04-18 | 2013-09-11 | 里亚塔医药公司 | 包含抗炎症药效团的化合物以及使用方法 |
US7915402B2 (en) | 2008-04-18 | 2011-03-29 | Reata Pharmaceuticals, Inc. | Antioxidant inflammation modulators: oleanolic acid derivatives with saturation in the C-ring |
WO2009129548A1 (en) | 2008-04-18 | 2009-10-22 | Reata Pharmaceuticals, Inc. | Antioxidant inflammation modulators: c-17 homologated oleanolic acid derivatives |
AU2009237579C1 (en) | 2008-04-18 | 2016-05-12 | Reata Pharmaceuticals Holdings, LLC | Antioxidant inflammation modulators: oleanolic acid derivatives with amino and other modifications at C-17 |
EP2309860B1 (en) | 2008-07-22 | 2014-01-08 | Trustees of Dartmouth College | Monocyclic cyanoenones and methods of use thereof |
PL2558105T3 (pl) * | 2010-04-12 | 2020-04-30 | Reata Pharmaceuticals, Inc. | Metylowany bardoksolon do leczenia otyłości |
EA025568B1 (ru) | 2010-12-17 | 2017-01-30 | Рита Фармасьютикалз, Инк. | Пиразолильные и пиримидинильные трициклические еноны в качестве антиоксидантных модуляторов воспаления |
EA026847B1 (ru) | 2011-03-11 | 2017-05-31 | Рита Фармасьютикалз, Инк. | C4-монометилтритерпеноидные производные и способы их применения |
KR101174701B1 (ko) * | 2011-12-29 | 2012-08-17 | 서울대학교산학협력단 | 진저레논 에이를 포함하는 비만 예방용 식품 조성물, 비만 치료용 약학조성물 및 비만 치료용 동물용 의약품 |
PE20150160A1 (es) | 2012-04-27 | 2015-02-19 | Reata Pharmaceuticals Inc | Derivados de 2,2-difluoropropionamida de bardoxolona metilo, formas polimorficas y metodos de uso de los mismos |
WO2013188818A1 (en) | 2012-06-15 | 2013-12-19 | Reata Pharmaceuticals, Inc. | A-ring epoxidized triterpenoid-based anti-inflammation modulators and methods of use thereof |
US9512094B2 (en) | 2012-09-10 | 2016-12-06 | Reata Pharmaceuticals, Inc. | C17-heteroaryl derivatives of oleanolic acid and methods of use thereof |
WO2014040052A2 (en) | 2012-09-10 | 2014-03-13 | Abbvie Inc. | Glycyrrhetinic acid derivatives and methods of use thereof |
US9278912B2 (en) | 2012-09-10 | 2016-03-08 | Reata Pharmaceuticals, Inc. | C13-hydroxy derivatives of oleanolic acid and methods of use thereof |
UY35023A (es) | 2012-09-10 | 2014-03-31 | Reata Pharmaceuticals Inc | Derivados c17-alcandiilo y alquendiilo del ácido oleanólico y sus métodos de uso |
RS58010B1 (sr) | 2012-09-27 | 2019-02-28 | Childrens Medical Ct Corp | Jedinjenja za lečenje gojaznosti i postupci za njihovu upotrebu |
TW201514192A (zh) | 2013-03-19 | 2015-04-16 | Daiichi Sankyo Co Ltd | 萜類衍生物 |
TW201936625A (zh) | 2013-04-24 | 2019-09-16 | 美商艾伯維有限公司 | 甲基巴多索龍之2,2-二氟丙醯胺衍生物、其多晶形及其使用方法 |
EA201690456A1 (ru) * | 2013-08-23 | 2016-06-30 | Рита Фармасьютикалз, Инк. | Способы лечения и предотвращения эндотелиальной дисфункции с применением бардоксолона метила или его аналогов |
WO2015112792A1 (en) | 2014-01-24 | 2015-07-30 | Abbvie Inc. | Aryl and arylalkyl substituted pyrazolyl and pyrimidinyl tricyclic enones as antioxidant inflammation modulators |
AU2015256178B2 (en) | 2014-05-05 | 2020-02-27 | The Board Of Regents Of The University Of Texas System | Methods and compositions comprising ursolic acid and/or resveratrol for treating obesity, diabetes, or cancer |
ES2770772T3 (es) | 2014-09-10 | 2020-07-03 | Daiichi Sankyo Co Ltd | Composición farmacéutica de liberación sostenida para el tratamiento y prevención de enfermedades oculares |
KR20170117092A (ko) | 2015-02-12 | 2017-10-20 | 리아타 파마슈티컬즈, 아이엔씨. | 항산화 염증 조절제로서의 이미다졸릴 트리사이클릭 에논 |
CN105017374B (zh) * | 2015-07-20 | 2017-03-01 | 山西大学 | 一种齐墩果酸内酯类衍生物及其制备方法和应用 |
US20170056373A1 (en) * | 2015-09-01 | 2017-03-02 | Syracuse University | Ghrelin o-acyltransferase inhibitors |
CA2998681C (en) | 2015-09-23 | 2024-02-06 | Reata Pharmaceuticals, Inc. | C4-modified oleanolic acid derivatives for inhibition of il-17 and other uses |
US11207333B2 (en) | 2016-09-08 | 2021-12-28 | Regenera Pharma Ltd. | Compositions comprising triterpenoids and uses thereof for treating optic neuropathy |
BR112019009256A2 (pt) | 2016-11-08 | 2019-07-16 | Reata Pharmaceuticals Inc | métodos para tratar síndrome de alport usando bardoxolona metil ou análogos do mesmo |
TWI831738B (zh) | 2016-12-16 | 2024-02-11 | 美商瑞塔醫藥有限責任公司 | 用於抑制RORγ及其他用途的嘧啶三環烯酮衍生物 |
CN116018136A (zh) * | 2020-04-29 | 2023-04-25 | 百爱及生物医药公司 | 用于治疗衰老相关病症的缺氧诱导因子脯氨酰羟化酶抑制剂 |
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2011
- 2011-04-12 PL PL11715645T patent/PL2558105T3/pl unknown
- 2011-04-12 WO PCT/US2011/032156 patent/WO2011130302A2/en active Application Filing
- 2011-04-12 EA EA201291031A patent/EA026567B1/ru not_active IP Right Cessation
- 2011-04-12 DK DK11715645.5T patent/DK2558105T3/da active
- 2011-04-12 ES ES11715645T patent/ES2768204T3/es active Active
- 2011-04-12 PT PT117156455T patent/PT2558105T/pt unknown
- 2011-04-12 MY MYPI2012004530A patent/MY163031A/en unknown
- 2011-04-12 RS RS20200073A patent/RS59850B1/sr unknown
- 2011-04-12 JP JP2013505061A patent/JP5990160B2/ja active Active
- 2011-04-12 LT LTEP11715645.5T patent/LT2558105T/lt unknown
- 2011-04-12 MX MX2012011892A patent/MX357596B/es active IP Right Grant
- 2011-04-12 BR BR112012026112-6A patent/BR112012026112B1/pt active IP Right Grant
- 2011-04-12 CA CA2795320A patent/CA2795320C/en active Active
- 2011-04-12 EP EP11715645.5A patent/EP2558105B1/en active Active
- 2011-04-12 CN CN201180028997.6A patent/CN102939089B/zh active Active
- 2011-04-12 HU HUE11715645A patent/HUE047994T2/hu unknown
- 2011-04-12 AU AU2011240690A patent/AU2011240690C1/en active Active
- 2011-04-12 US US13/085,338 patent/US10105372B2/en active Active
- 2011-04-12 ME MEP-2020-4A patent/ME03713B/me unknown
- 2011-04-12 TW TW100112717A patent/TWI558724B/zh not_active IP Right Cessation
- 2011-04-12 NZ NZ602826A patent/NZ602826A/en unknown
- 2011-04-12 SG SG10201808661XA patent/SG10201808661XA/en unknown
- 2011-04-12 SG SG2012075834A patent/SG184830A1/en unknown
- 2011-04-12 KR KR1020127029558A patent/KR101819699B1/ko active IP Right Grant
- 2011-04-12 SI SI201131840T patent/SI2558105T1/sl unknown
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2012
- 2012-10-08 ZA ZA2012/07518A patent/ZA201207518B/en unknown
- 2012-10-09 IL IL222273A patent/IL222273B/en active IP Right Grant
- 2012-10-12 CL CL2012002859A patent/CL2012002859A1/es unknown
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2018
- 2018-09-13 US US16/130,242 patent/US11911395B2/en active Active
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2019
- 2019-12-19 HR HRP20192291TT patent/HRP20192291T1/hr unknown
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2020
- 2020-01-09 CY CY20201100022T patent/CY1122480T1/el unknown
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