CY1115938T1 - Νεα συνθεση για αυξηση της bio-διαθεσιμοτητας της νεουρτουρινης (neurturin) - Google Patents
Νεα συνθεση για αυξηση της bio-διαθεσιμοτητας της νεουρτουρινης (neurturin)Info
- Publication number
- CY1115938T1 CY1115938T1 CY20151100013T CY151100013T CY1115938T1 CY 1115938 T1 CY1115938 T1 CY 1115938T1 CY 20151100013 T CY20151100013 T CY 20151100013T CY 151100013 T CY151100013 T CY 151100013T CY 1115938 T1 CY1115938 T1 CY 1115938T1
- Authority
- CY
- Cyprus
- Prior art keywords
- neurturin
- bio
- availability
- increasing
- new composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/717—Celluloses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Inorganic Chemistry (AREA)
- Marine Sciences & Fisheries (AREA)
- Endocrinology (AREA)
- Transplantation (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Η παρούσα εφεύρεση σχετίζεται με συνθέσεις με παράγοντες ανάπτυξης πρωτεΐνης, ειδικότερα νεουρτουρίνης (neurturin) σαν δραστικών συστατικών και πολύ-ανιονικών εκδόχων χαμηλού μοριακού βάρους που έχουν αυξημένη βίο-διαθεσιμότητα.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06013135A EP1872790A1 (en) | 2006-06-26 | 2006-06-26 | New formulation for increasing bioavailability of neurturin |
EP07764869.9A EP2040736B1 (en) | 2006-06-26 | 2007-06-26 | New formulation for increasing bioavailability of neurturin |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1115938T1 true CY1115938T1 (el) | 2017-01-25 |
Family
ID=37440830
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20151100013T CY1115938T1 (el) | 2006-06-26 | 2015-01-07 | Νεα συνθεση για αυξηση της bio-διαθεσιμοτητας της νεουρτουρινης (neurturin) |
Country Status (9)
Country | Link |
---|---|
US (3) | US20090258829A1 (el) |
EP (3) | EP1872790A1 (el) |
CY (1) | CY1115938T1 (el) |
DK (1) | DK2040736T3 (el) |
ES (1) | ES2527093T3 (el) |
PL (1) | PL2040736T3 (el) |
PT (1) | PT2040736E (el) |
SI (1) | SI2040736T1 (el) |
WO (1) | WO2008000447A1 (el) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050222070A1 (en) | 2002-05-29 | 2005-10-06 | Develogen Aktiengesellschaft Fuer Entwicklungsbiologische Forschung | Pancreas-specific proteins |
ES2329583T3 (es) | 2003-11-27 | 2009-11-27 | Develogen Aktiengesellschaft | Metodo para prevenir y tratar la diabetes con neurturina. |
JP2011503019A (ja) * | 2007-11-05 | 2011-01-27 | デベローゲン アクティーゲンゲゼルゲゼルシャフト | 薬学的使用のための新規のニュールツリン複合体 |
US8445432B2 (en) | 2009-10-30 | 2013-05-21 | Ntf Therapeutics Inc | Neurturin molecules |
US9127083B2 (en) | 2009-10-30 | 2015-09-08 | Ntf Therapeutics, Inc. | Neurturin molecules |
CN106727289A (zh) * | 2016-11-11 | 2017-05-31 | 上海雅本化学有限公司 | 一种磺达肝癸钠组合物注射液及其制备方法 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4518584A (en) | 1983-04-15 | 1985-05-21 | Cetus Corporation | Human recombinant interleukin-2 muteins |
DE3572982D1 (en) | 1984-03-06 | 1989-10-19 | Takeda Chemical Industries Ltd | Chemically modified lymphokine and production thereof |
ATE135370T1 (de) | 1988-12-22 | 1996-03-15 | Kirin Amgen Inc | Chemisch modifizierte granulocytenkolonie erregender faktor |
EP1241258A3 (en) | 1989-10-16 | 2003-12-10 | Amgen Inc. | Stem cell factor |
AU1052492A (en) * | 1991-01-31 | 1992-08-06 | Farmitalia Carlo Erba S.R.L. | Synergistic composition comprising a fibroblast growth factor and a sulfated polylsaccharide, for use as antiviral agent |
HU220795B1 (hu) | 1991-09-20 | 2002-05-28 | Amgen Inc. | Gliasejtvonal-eredetű neurotróf faktorfehérjék, továbbá berendezések és gyógyászati készítmények idegsejtkárosodás megelőzésére és kezelésére |
US5464815A (en) * | 1993-09-08 | 1995-11-07 | Genentech, Inc. | Inhibition of heparin-binding |
US5739307A (en) | 1995-08-28 | 1998-04-14 | Washington University | Polynucleotide encoding neurturin neurotrophic factor |
US6043221A (en) | 1997-07-30 | 2000-03-28 | Amgen Inc. | Method for preventing and treating hearing loss using a neuturin protein product |
FR2812551B1 (fr) * | 2000-08-07 | 2003-03-28 | Virsol | Forme pharmaceutique comprenant un materiau support a base de methylidene malonate et un facteur de regulation cellulaire |
JP2005503141A (ja) | 2001-07-24 | 2005-02-03 | ノボ ノルディスク アクティーゼルスカブ | アシル化ポリペプチドを作出するための方法 |
JP2005527614A (ja) | 2002-05-29 | 2005-09-15 | デヴェロゲン アクチエンゲゼルシャフト フュア エントヴィックルングスビオローギッシェ フォルシュング | 膵臓特異性タンパク質 |
ES2329583T3 (es) * | 2003-11-27 | 2009-11-27 | Develogen Aktiengesellschaft | Metodo para prevenir y tratar la diabetes con neurturina. |
BRPI0710800A2 (pt) * | 2006-04-25 | 2012-01-17 | Univ California | administração de fatores de crescimento para o tratamento de distúrbios de snc |
-
2006
- 2006-06-26 EP EP06013135A patent/EP1872790A1/en not_active Withdrawn
-
2007
- 2007-06-26 US US12/304,555 patent/US20090258829A1/en not_active Abandoned
- 2007-06-26 ES ES07764869.9T patent/ES2527093T3/es active Active
- 2007-06-26 PT PT77648699T patent/PT2040736E/pt unknown
- 2007-06-26 PL PL07764869T patent/PL2040736T3/pl unknown
- 2007-06-26 WO PCT/EP2007/005652 patent/WO2008000447A1/en active Application Filing
- 2007-06-26 SI SI200731576T patent/SI2040736T1/sl unknown
- 2007-06-26 EP EP07764869.9A patent/EP2040736B1/en not_active Not-in-force
- 2007-06-26 EP EP11162700A patent/EP2371379A3/en not_active Withdrawn
- 2007-06-26 DK DK07764869.9T patent/DK2040736T3/en active
-
2012
- 2012-08-27 US US13/595,706 patent/US20130053313A1/en not_active Abandoned
-
2013
- 2013-09-26 US US14/038,652 patent/US20140162948A1/en not_active Abandoned
-
2015
- 2015-01-07 CY CY20151100013T patent/CY1115938T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
WO2008000447A1 (en) | 2008-01-03 |
EP2371379A3 (en) | 2012-12-26 |
PL2040736T3 (pl) | 2015-04-30 |
US20130053313A1 (en) | 2013-02-28 |
EP2371379A2 (en) | 2011-10-05 |
US20090258829A1 (en) | 2009-10-15 |
SI2040736T1 (sl) | 2015-03-31 |
DK2040736T3 (en) | 2015-01-12 |
PT2040736E (pt) | 2014-12-31 |
EP2040736B1 (en) | 2014-12-10 |
US20140162948A1 (en) | 2014-06-12 |
EP2040736A1 (en) | 2009-04-01 |
EP1872790A1 (en) | 2008-01-02 |
ES2527093T3 (es) | 2015-01-20 |
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