CY1110841T1 - Σταθεροποιημενος φαρμακευτικος παραγοντας λευκοτριενιου β4 (ltb4) - Google Patents
Σταθεροποιημενος φαρμακευτικος παραγοντας λευκοτριενιου β4 (ltb4)Info
- Publication number
- CY1110841T1 CY1110841T1 CY20101100940T CY101100940T CY1110841T1 CY 1110841 T1 CY1110841 T1 CY 1110841T1 CY 20101100940 T CY20101100940 T CY 20101100940T CY 101100940 T CY101100940 T CY 101100940T CY 1110841 T1 CY1110841 T1 CY 1110841T1
- Authority
- CY
- Cyprus
- Prior art keywords
- ltb4
- lefcotrien
- stabilized
- formulation
- life
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Η παρούσα εφεύρεση σχετίζεται με νέο φαρμακευτικό σκεύασμα που περιλαμβάνει παράγοντα LΤΒ4 σε αλκαλικό pH, αποτελεσματικό στη σταθεροποίηση του παράγοντα LΤΒ4 και παρέχει σκεύασμα με αυξημένη διάρκεια ζωής. Το σκεύασμα της παρούσας εφεύρεσης έχει αυξημένη διάρκεια ζωής κατά προτίμηση τουλάχιστον 24 μήνες.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61096204P | 2004-09-20 | 2004-09-20 | |
US63500904P | 2004-12-13 | 2004-12-13 | |
US63548204P | 2004-12-14 | 2004-12-14 | |
EP05786891A EP1796730B1 (en) | 2004-09-20 | 2005-09-20 | Stabilized leukotriene b4 (ltb4) agent pharmaceutical |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1110841T1 true CY1110841T1 (el) | 2015-06-10 |
Family
ID=35902513
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20101100940T CY1110841T1 (el) | 2004-09-20 | 2010-10-20 | Σταθεροποιημενος φαρμακευτικος παραγοντας λευκοτριενιου β4 (ltb4) |
Country Status (23)
Country | Link |
---|---|
US (1) | US8664271B2 (el) |
EP (1) | EP1796730B1 (el) |
JP (1) | JP4767256B2 (el) |
KR (1) | KR101109735B1 (el) |
CN (1) | CN101039698B (el) |
AT (1) | ATE474603T1 (el) |
AU (1) | AU2005286161B2 (el) |
BR (1) | BRPI0516957A (el) |
CA (1) | CA2581156C (el) |
CY (1) | CY1110841T1 (el) |
DE (1) | DE602005022462D1 (el) |
DK (1) | DK1796730T3 (el) |
EA (1) | EA012982B1 (el) |
ES (1) | ES2349410T3 (el) |
HK (1) | HK1103652A1 (el) |
NO (1) | NO20071977L (el) |
NZ (1) | NZ553982A (el) |
PL (1) | PL1796730T3 (el) |
PT (1) | PT1796730E (el) |
SI (1) | SI1796730T1 (el) |
TW (1) | TWI361078B (el) |
UA (1) | UA96257C2 (el) |
WO (1) | WO2006032977A2 (el) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1840114A1 (en) * | 2006-03-30 | 2007-10-03 | LTB4 Sweden AB | Crystalline Leukotriene B4 |
CN102435443B (zh) * | 2011-09-08 | 2014-04-02 | 中国汽车技术研究中心 | 汽车催化器快速老化数据采集*** |
JP6483593B2 (ja) * | 2015-03-06 | 2019-03-13 | アークレイ株式会社 | 血液検査装置および血液検査方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0179959A1 (en) * | 1982-04-20 | 1986-05-07 | Merck Frosst Canada Inc. | Conjugates of leukotrienes with proteins |
US4568559A (en) * | 1984-02-06 | 1986-02-04 | Biotek, Inc. | Composite core coated microparticles and process of preparing same |
GB2189698A (en) * | 1986-04-30 | 1987-11-04 | Haessle Ab | Coated omeprazole tablets |
US4876505A (en) * | 1988-05-27 | 1989-10-24 | Westinghouse Electric Corp. | Apparatus and method for monitoring steam turbine shroud clearance |
US5789441A (en) * | 1996-02-15 | 1998-08-04 | Virocell Inc. | Leukotriene B4 as an antiviral and anti-neoplastic agent |
US20040132820A1 (en) | 1996-02-15 | 2004-07-08 | Jean Gosselin | Agents with leukotriene B4-like antiviral (DNA) and anti-neoplastic activities |
US5780055A (en) * | 1996-09-06 | 1998-07-14 | University Of Maryland, Baltimore | Cushioning beads and tablet comprising the same capable of forming a suspension |
US5909734A (en) * | 1996-12-03 | 1999-06-08 | Regents Of The University Of Michigan | Administration of products of the 5-lipoxygenase metabolic pathway to enhance antimicrobial defense |
US7914800B2 (en) * | 2001-07-05 | 2011-03-29 | Ltb4 Sweden Ab | LTB4 as vaccine adjuvant |
US20030232858A1 (en) | 2002-06-14 | 2003-12-18 | Barker Ronnie C. | Use of hydroxyeicosatetraenoic acid compounds to treat dry mouth |
-
2005
- 2005-09-20 ES ES05786891T patent/ES2349410T3/es active Active
- 2005-09-20 KR KR1020077009102A patent/KR101109735B1/ko not_active IP Right Cessation
- 2005-09-20 BR BRPI0516957-7A patent/BRPI0516957A/pt not_active IP Right Cessation
- 2005-09-20 AU AU2005286161A patent/AU2005286161B2/en not_active Ceased
- 2005-09-20 US US11/231,359 patent/US8664271B2/en not_active Expired - Fee Related
- 2005-09-20 WO PCT/IB2005/002781 patent/WO2006032977A2/en active Application Filing
- 2005-09-20 UA UAA200704260A patent/UA96257C2/uk unknown
- 2005-09-20 SI SI200531135T patent/SI1796730T1/sl unknown
- 2005-09-20 NZ NZ553982A patent/NZ553982A/en not_active IP Right Cessation
- 2005-09-20 DK DK05786891.1T patent/DK1796730T3/da active
- 2005-09-20 CA CA2581156A patent/CA2581156C/en not_active Expired - Fee Related
- 2005-09-20 AT AT05786891T patent/ATE474603T1/de active
- 2005-09-20 PL PL05786891T patent/PL1796730T3/pl unknown
- 2005-09-20 TW TW094132426A patent/TWI361078B/zh active
- 2005-09-20 CN CN2005800317006A patent/CN101039698B/zh not_active Expired - Fee Related
- 2005-09-20 DE DE602005022462T patent/DE602005022462D1/de active Active
- 2005-09-20 EP EP05786891A patent/EP1796730B1/en not_active Not-in-force
- 2005-09-20 EA EA200700676A patent/EA012982B1/ru not_active IP Right Cessation
- 2005-09-20 JP JP2007531861A patent/JP4767256B2/ja not_active Expired - Fee Related
- 2005-09-20 PT PT05786891T patent/PT1796730E/pt unknown
-
2007
- 2007-04-18 NO NO20071977A patent/NO20071977L/no not_active Application Discontinuation
- 2007-11-08 HK HK07112199.7A patent/HK1103652A1/xx not_active IP Right Cessation
-
2010
- 2010-10-20 CY CY20101100940T patent/CY1110841T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
HK1103652A1 (en) | 2007-12-28 |
US20060063837A1 (en) | 2006-03-23 |
TWI361078B (en) | 2012-04-01 |
DE602005022462D1 (de) | 2010-09-02 |
ES2349410T3 (es) | 2011-01-03 |
CA2581156C (en) | 2011-07-12 |
WO2006032977A2 (en) | 2006-03-30 |
AU2005286161B2 (en) | 2010-09-09 |
EP1796730B1 (en) | 2010-07-21 |
PL1796730T3 (pl) | 2010-12-31 |
JP4767256B2 (ja) | 2011-09-07 |
WO2006032977A3 (en) | 2006-07-13 |
CA2581156A1 (en) | 2006-03-30 |
US8664271B2 (en) | 2014-03-04 |
CN101039698A (zh) | 2007-09-19 |
BRPI0516957A (pt) | 2008-09-30 |
DK1796730T3 (da) | 2010-11-01 |
KR101109735B1 (ko) | 2012-02-17 |
SI1796730T1 (sl) | 2010-12-31 |
EP1796730A2 (en) | 2007-06-20 |
EA012982B1 (ru) | 2010-02-26 |
NZ553982A (en) | 2009-09-25 |
CN101039698B (zh) | 2011-11-09 |
AU2005286161A1 (en) | 2006-03-30 |
PT1796730E (pt) | 2010-10-26 |
EA200700676A1 (ru) | 2007-10-26 |
KR20070085277A (ko) | 2007-08-27 |
UA96257C2 (uk) | 2011-10-25 |
TW200626175A (en) | 2006-08-01 |
NO20071977L (no) | 2007-04-18 |
JP2008513431A (ja) | 2008-05-01 |
ATE474603T1 (de) | 2010-08-15 |
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