CY1107368T1 - Νεα παραγωγα 4-βενζυλιδενο-πιπεριδινης - Google Patents
Νεα παραγωγα 4-βενζυλιδενο-πιπεριδινηςInfo
- Publication number
- CY1107368T1 CY1107368T1 CY20081100349T CY081100349T CY1107368T1 CY 1107368 T1 CY1107368 T1 CY 1107368T1 CY 20081100349 T CY20081100349 T CY 20081100349T CY 081100349 T CY081100349 T CY 081100349T CY 1107368 T1 CY1107368 T1 CY 1107368T1
- Authority
- CY
- Cyprus
- Prior art keywords
- benzylidene
- piperidine derivatives
- new
- nmda
- analgesics
- Prior art date
Links
- QMQNIKYRPSFQKB-UHFFFAOYSA-N 4-benzylidenepiperidine Chemical class C1CNCCC1=CC1=CC=CC=C1 QMQNIKYRPSFQKB-UHFFFAOYSA-N 0.000 title abstract 2
- HOKKHZGPKSLGJE-GSVOUGTGSA-N N-Methyl-D-aspartic acid Chemical compound CN[C@@H](C(O)=O)CC(O)=O HOKKHZGPKSLGJE-GSVOUGTGSA-N 0.000 abstract 1
- 102000034527 Retinoid X Receptors Human genes 0.000 abstract 1
- 108010038912 Retinoid X Receptors Proteins 0.000 abstract 1
- 229940035676 analgesics Drugs 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 239000002464 receptor antagonist Substances 0.000 abstract 1
- 229940044551 receptor antagonist Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Abstract
Η παρούσα εφεύρεση αναφέρεται σε νέα παράγωγα 4-βενζυλιδενο-πιπεριδίνης του τύπου (I), χρήσιμα ως NMDA, σε μια συγκεκριμένη υπομονάδα NR2B που περιέχει ανταγωνιστές υποδοχέων και αναλγητικά.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0401522A HUP0401522A2 (en) | 2004-07-29 | 2004-07-29 | New 4-benzylidene-piperidine derivatives, pharmaceutical compositions containing the same and process for their preparation |
| EP05763197A EP1773810B1 (en) | 2004-07-29 | 2005-07-21 | New 4-benzylidene-piperidin derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1107368T1 true CY1107368T1 (el) | 2012-12-19 |
Family
ID=89985407
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20081100349T CY1107368T1 (el) | 2004-07-29 | 2008-03-27 | Νεα παραγωγα 4-βενζυλιδενο-πιπεριδινης |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US8008326B2 (el) |
| EP (1) | EP1773810B1 (el) |
| JP (1) | JP4814880B2 (el) |
| KR (1) | KR20070058428A (el) |
| CN (1) | CN1989128A (el) |
| AP (1) | AP2074A (el) |
| AT (1) | ATE387440T1 (el) |
| AU (1) | AU2005266159B2 (el) |
| BR (1) | BRPI0513902A (el) |
| CA (1) | CA2574148A1 (el) |
| CY (1) | CY1107368T1 (el) |
| DE (1) | DE602005005064T2 (el) |
| DK (1) | DK1773810T3 (el) |
| EA (1) | EA011241B1 (el) |
| ES (1) | ES2302214T3 (el) |
| GE (1) | GEP20084492B (el) |
| HK (1) | HK1105966A1 (el) |
| HR (1) | HRP20080127T3 (el) |
| HU (1) | HUP0401522A2 (el) |
| IL (1) | IL179484A0 (el) |
| MA (1) | MA28816B1 (el) |
| MX (1) | MX2007001055A (el) |
| NO (1) | NO20071108L (el) |
| NZ (1) | NZ552137A (el) |
| PL (1) | PL1773810T3 (el) |
| PT (1) | PT1773810E (el) |
| RS (1) | RS50573B (el) |
| SI (1) | SI1773810T1 (el) |
| TN (1) | TNSN07018A1 (el) |
| UA (1) | UA87862C2 (el) |
| WO (1) | WO2006010964A1 (el) |
| ZA (1) | ZA200700320B (el) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1988077A4 (en) | 2006-02-23 | 2009-09-02 | Shionogi & Co | NUCLEIC HETEROCYCLIC DERIVATIVES SUBSTITUTED BY CYCLIC GROUPS |
| CN101426381A (zh) * | 2006-04-21 | 2009-05-06 | 西诺米克斯公司 | 含有高效鲜味调料的可食用组合物及其制备方法 |
| WO2007146550A2 (en) * | 2006-06-08 | 2007-12-21 | Bristol-Myers Squibb Company | Alkene piperidine derivatives as antiviral agents |
| EA201170007A1 (ru) * | 2008-07-08 | 2011-08-30 | Рихтер Гедеон Нирт. | Новая кристаллическая форма 2-[4-(4-фторбензил)пиперидин-1-ил]-2-оксо-n-(2-оксо-2,3-дигидробензоксазол-6-ил)ацетамида |
| IN2012DN06631A (el) | 2010-02-16 | 2015-10-23 | Pfizer | |
| EP2615084B1 (en) | 2010-09-07 | 2016-01-06 | Taiho Pharmaceutical Co., Ltd. | Prostaglandin d synthase inhibitory piperidine compounds |
| US20120322824A1 (en) * | 2011-01-04 | 2012-12-20 | Surratt Christopher K | Cocaine Antagonist/Antidepressant Pharmaceutical Preparations |
| JP6042968B2 (ja) | 2012-04-20 | 2016-12-14 | ユセベ ファルマ ソシエテ アノニム | パーキンソン病の処置方法 |
| WO2016030443A1 (en) | 2014-08-28 | 2016-03-03 | Asceneuron Sa | Glycosidase inhibitors |
| DK3389658T3 (da) * | 2015-12-18 | 2021-01-11 | Merck Sharp & Dohme | Glycosidasehæmmere og anvendelser deraf |
| KR20180132629A (ko) | 2016-02-25 | 2018-12-12 | 아셰뉴론 에스아 | 글리코시다제 저해제 |
| ES2879351T3 (es) | 2016-02-25 | 2021-11-22 | Asceneuron Sa | Sales de derivados de piperazina obtenidas por adición de ácidos |
| US11261183B2 (en) | 2016-02-25 | 2022-03-01 | Asceneuron Sa | Sulfoximine glycosidase inhibitors |
| MA43680A (fr) | 2016-02-25 | 2018-11-28 | Asceneuron Sa | Inhibiteurs de glycosidases |
| US9486444B1 (en) | 2016-03-21 | 2016-11-08 | King Saud University | Anti-cancer compound |
| US11213525B2 (en) | 2017-08-24 | 2022-01-04 | Asceneuron Sa | Linear glycosidase inhibitors |
| US11795165B2 (en) | 2018-08-22 | 2023-10-24 | Asceneuron Sa | Tetrahydro-benzoazepine glycosidase inhibitors |
| WO2020039029A1 (en) | 2018-08-22 | 2020-02-27 | Asceneuron S. A. | Spiro compounds as glycosidase inhibitors |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA9610738B (en) * | 1995-12-22 | 1997-06-24 | Warner Lambert Co | Subtype selective nmda receptor ligands and the use thereof |
| TW498067B (en) * | 1996-07-19 | 2002-08-11 | Hoffmann La Roche | 4-hydroxy-piperidine derivatives |
| CA2220649C (en) | 1996-12-03 | 2007-02-13 | F. Hoffmann-La Roche Ag | 4-hydroxy-piperidine derivatives |
| MXPA04000737A (es) | 2001-07-24 | 2004-07-08 | Richter Gedeon Vegyeszet | Derivados de piperidina como antagonistas receptores de nmda. |
-
2004
- 2004-07-29 HU HU0401522A patent/HUP0401522A2/hu unknown
-
2005
- 2005-07-21 AT AT05763197T patent/ATE387440T1/de active
- 2005-07-21 PL PL05763197T patent/PL1773810T3/pl unknown
- 2005-07-21 SI SI200530213T patent/SI1773810T1/sl unknown
- 2005-07-21 CA CA002574148A patent/CA2574148A1/en not_active Abandoned
- 2005-07-21 MX MX2007001055A patent/MX2007001055A/es active IP Right Grant
- 2005-07-21 AP AP2006003839A patent/AP2074A/en active
- 2005-07-21 UA UAA200702171A patent/UA87862C2/ru unknown
- 2005-07-21 ES ES05763197T patent/ES2302214T3/es active Active
- 2005-07-21 PT PT05763197T patent/PT1773810E/pt unknown
- 2005-07-21 AU AU2005266159A patent/AU2005266159B2/en not_active Ceased
- 2005-07-21 BR BRPI0513902-3A patent/BRPI0513902A/pt not_active IP Right Cessation
- 2005-07-21 KR KR1020077000262A patent/KR20070058428A/ko not_active Application Discontinuation
- 2005-07-21 DK DK05763197T patent/DK1773810T3/da active
- 2005-07-21 EP EP05763197A patent/EP1773810B1/en active Active
- 2005-07-21 JP JP2007523160A patent/JP4814880B2/ja not_active Expired - Fee Related
- 2005-07-21 US US11/658,789 patent/US8008326B2/en not_active Expired - Fee Related
- 2005-07-21 NZ NZ552137A patent/NZ552137A/xx not_active IP Right Cessation
- 2005-07-21 CN CNA2005800243746A patent/CN1989128A/zh active Pending
- 2005-07-21 EA EA200700367A patent/EA011241B1/ru not_active IP Right Cessation
- 2005-07-21 DE DE602005005064T patent/DE602005005064T2/de active Active
- 2005-07-21 RS RSP-2008/0123A patent/RS50573B/sr unknown
- 2005-07-21 GE GEAP20059892A patent/GEP20084492B/en unknown
- 2005-07-21 WO PCT/HU2005/000077 patent/WO2006010964A1/en active Application Filing
-
2006
- 2006-11-22 IL IL179484A patent/IL179484A0/en unknown
-
2007
- 2007-01-11 ZA ZA200700320A patent/ZA200700320B/en unknown
- 2007-01-17 TN TNP2007000018A patent/TNSN07018A1/en unknown
- 2007-02-22 MA MA29703A patent/MA28816B1/fr unknown
- 2007-02-27 NO NO20071108A patent/NO20071108L/no not_active Application Discontinuation
- 2007-10-17 HK HK07111209A patent/HK1105966A1/xx not_active IP Right Cessation
-
2008
- 2008-03-20 HR HR20080127T patent/HRP20080127T3/xx unknown
- 2008-03-27 CY CY20081100349T patent/CY1107368T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1107368T1 (el) | Νεα παραγωγα 4-βενζυλιδενο-πιπεριδινης | |
| EA200700365A1 (ru) | Производные индол-2-карбоксамидина как антагонисты nmda рецептора | |
| CY1118630T1 (el) | Στερεες μορφες 3-(6-(1-(2,2-διφθοροβενζο[d][1,3]διοξολ-5-υλο)-κυκλοπροπανοκαρβοξαμ1δο)-3-μεθυλοπυριδιν-3-υλο)-βενζοϊκου οξεος | |
| CY1109015T1 (el) | Διφαινυλ ενωσεις χρησιμες ως ανταγωνιστες μουσκαρινικου υποδοχεα | |
| ATE422198T1 (de) | Arylsulfonylnaphthalinderivate als 5ht2a- antagonisten | |
| NO20052739D0 (no) | CCR5-antagonister som medikamenter | |
| CY1110064T1 (el) | Παραγωγα φαινυλ-πιπεραζινης ως αναστολεις επαναπροσληψης σεροτονινης | |
| NO20051260L (no) | Arylsubstituerte diazabicykloalkaner som nikotinacetylcholinagonister | |
| ATE493386T1 (de) | Trans-3-aza-bicyclo-ä3.1.0ü-hexan-derivate | |
| DE602008002934D1 (de) | 2-cyclopropylthiazolderivate | |
| DK1599478T3 (da) | Dihydropteridinoner, fremgangsmåde til fremstilling af disse og anvendelse af disse som lægemiddel | |
| ATE496051T1 (de) | Pyrazolotetrahydropyridinderivate als orexinrezeptorantagonisten | |
| NO20032253D0 (no) | Piperazinylpyrazinforbindelser som antagonister av serotonin 5-HT2-reseptorer | |
| CY1109998T1 (el) | Ενδυναμωτες υποδοχεων γλουταμινικου | |
| CY1105994T1 (el) | Aναδιαταγμενες πεντανολες, μεθοδος για την παραγωγη αυτων και η χρηση αυτων ως αντιφλεγμονωδων | |
| SMAP200600024A (it) | 2,6-Biseteroaril-4-amminopirimidine come antagonisti del recettore dell'adenosia | |
| NO20083582L (no) | Pyridin-2-karboksamide derivater | |
| DK1833791T3 (da) | 2,3,4,9-tetrahydor-1H-carbazolderivater som CRTH2 receptorantagonister | |
| CY1108321T1 (el) | Καινοφανη παραγωγα δικαρβοξυλικου οξεος | |
| NO20081001L (no) | Derivater av karboksamid som antagonister for muskarinisk reseptor | |
| NO20090779L (no) | 5,6-bisaryl-2-pyridin-karboksamidderivater, fremstilling og anvendelse derav i terapeutika som uretosin II receptorantagonister | |
| GEP20084494B (en) | New heterocyclic carboxylic acid amide derivatives | |
| DE602004004278D1 (de) | 4-cycloalkylaminopyrazolopyrimidin als nmda/nr2b-antagonisten | |
| DK1648882T3 (da) | 3-fluor-piperidiner som NMDA/NR2B-antagonister | |
| EA200700364A1 (ru) | Производные амида кинуреновой кислоты как антагонисты nr2b подтипа рецептора nmda |