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Priority to CU20100261ApriorityCriticalpatent/CU20100261A7/en
Publication of CU20100261A7publicationCriticalpatent/CU20100261A7/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
La presente invención proporciona compuestos orgánicos novedosos de la fórmula I: ESPACIO PARA LA FÓRMULA métodos de uso, y composiciones farmacéuticas de los mismos.The present invention provides novel organic compounds of the formula I: SPACE FOR FORMULA methods of use, and pharmaceutical compositions thereof.
Compounds derived from 5-alkynyl-pyrimidines, kinase inhibitors; pharmaceutical compositions containing them; and its use for the treatment and / or prevention of cancer, infections, inflammatory and autoimmune diseases.
Compounds derived from 2-oxo-piperidine and 1,1-dioxide-thiazine, mdm2 inhibitors; pharmaceutical composition that includes them; and its use for the treatment of cancer.
Compounds derived from substituted pyrrolidine-2-carboxamides; mdm2-p53 interaction inhibitors; pharmaceutical composition; and its use for the treatment of cancer, particularly solid tumors.