CS212264B2 - Method of making the 5-m-tolyloxyuracile - Google Patents

Method of making the 5-m-tolyloxyuracile Download PDF

Info

Publication number
CS212264B2
CS212264B2 CS774680A CS468077A CS212264B2 CS 212264 B2 CS212264 B2 CS 212264B2 CS 774680 A CS774680 A CS 774680A CS 468077 A CS468077 A CS 468077A CS 212264 B2 CS212264 B2 CS 212264B2
Authority
CS
Czechoslovakia
Prior art keywords
tolyloxyuracil
acid
compound
sodium
gastric
Prior art date
Application number
CS774680A
Other languages
Czech (cs)
English (en)
Inventor
Christopher Andrew Lipinski
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of CS212264B2 publication Critical patent/CS212264B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CS774680A 1976-07-16 1977-07-13 Method of making the 5-m-tolyloxyuracile CS212264B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/706,123 US4080454A (en) 1976-07-16 1976-07-16 5-M-Tolyloxyuracil, anti-ulcer agent

Publications (1)

Publication Number Publication Date
CS212264B2 true CS212264B2 (en) 1982-03-26

Family

ID=24836300

Family Applications (1)

Application Number Title Priority Date Filing Date
CS774680A CS212264B2 (en) 1976-07-16 1977-07-13 Method of making the 5-m-tolyloxyuracile

Country Status (29)

Country Link
US (1) US4080454A (fi)
JP (1) JPS5337673A (fi)
AR (1) AR213652A1 (fi)
AT (1) AT351561B (fi)
BE (1) BE856710A (fi)
CA (1) CA1061788A (fi)
CH (1) CH622512A5 (fi)
CS (1) CS212264B2 (fi)
DD (1) DD131556A5 (fi)
DE (1) DE2731736A1 (fi)
DK (1) DK139029B (fi)
EG (1) EG12762A (fi)
ES (1) ES460686A1 (fi)
FI (1) FI772183A (fi)
FR (1) FR2358399A1 (fi)
GB (1) GB1542178A (fi)
GR (1) GR68686B (fi)
HU (1) HU177713B (fi)
IL (1) IL52409A (fi)
LU (1) LU77764A1 (fi)
NL (1) NL7707729A (fi)
NO (1) NO772489L (fi)
PH (1) PH13190A (fi)
PL (1) PL103783B1 (fi)
PT (1) PT66808B (fi)
SE (1) SE421125B (fi)
SU (1) SU673169A3 (fi)
YU (1) YU171677A (fi)
ZA (1) ZA773927B (fi)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55158095A (en) * 1979-05-25 1980-12-09 Zenkosha Tokei Kk Controller for washing machine
JPS5822406U (ja) * 1981-08-04 1983-02-12 トキコ株式会社 消音器
US7776870B2 (en) 2005-08-22 2010-08-17 Melior Pharmaceuticals I, Inc. Methods for modulating Lyn kinase activity and treating related disorders
WO2008103692A2 (en) * 2007-02-20 2008-08-28 Melior Pharmaceuticals I, Inc. Methods of identifying activators of lyn kinase
CA2693809A1 (en) * 2007-07-23 2009-01-29 Melior Discovery, Inc. Methods of activating irs-1 and akt
US8552184B2 (en) * 2008-07-03 2013-10-08 Melior Pharmaceuticals I, Inc. Compounds and methods for treating disorders related to glucose metabolism
WO2011150300A1 (en) * 2010-05-28 2011-12-01 Melior Pharmaceuticals I, Inc. Prevention of pancreatic beta cell degeneration
EP3609500A4 (en) 2017-04-10 2020-08-19 Melior Pharmaceuticals I, Inc. ADIPOCYTE TREATMENT
AU2019223911A1 (en) 2018-02-21 2020-07-23 Melior Pharmaceuticals I, Inc. Treatment of liver diseases

Also Published As

Publication number Publication date
PH13190A (en) 1980-01-16
AT351561B (de) 1979-08-10
BE856710A (fr) 1978-01-11
JPS5337673A (en) 1978-04-06
CA1061788A (en) 1979-09-04
ZA773927B (en) 1978-05-30
CH622512A5 (fi) 1981-04-15
SU673169A3 (ru) 1979-07-05
NO772489L (no) 1978-01-17
PL199633A1 (pl) 1978-04-10
FI772183A (fi) 1978-01-17
SE421125B (sv) 1981-11-30
DK139029B (da) 1978-12-04
LU77764A1 (fi) 1978-02-02
GR68686B (fi) 1982-02-01
PL103783B1 (pl) 1979-07-31
JPS5512017B2 (fi) 1980-03-29
PT66808B (en) 1978-12-21
DK139029C (fi) 1979-05-07
FR2358399A1 (fr) 1978-02-10
DE2731736A1 (de) 1978-01-26
SE7707471L (sv) 1978-01-17
AU2663877A (en) 1978-05-18
IL52409A (en) 1979-11-30
GB1542178A (en) 1979-03-14
ES460686A1 (es) 1978-12-01
DD131556A5 (de) 1978-07-05
HU177713B (en) 1981-12-28
IL52409A0 (en) 1977-08-31
DK318177A (fi) 1978-01-17
ATA509277A (de) 1979-01-15
EG12762A (en) 1979-12-31
PT66808A (en) 1977-08-01
AR213652A1 (es) 1979-02-28
US4080454A (en) 1978-03-21
FR2358399B1 (fi) 1980-10-17
YU171677A (en) 1982-06-30
NL7707729A (nl) 1978-01-18

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